Early Exposure To Germs Has Lasting Benefits

ananyo writes "Exposure to germs in childhood is thought to help strengthen the immune system and protect children from developing allergies and asthma, but the pathways by which this occurs have been unclear. Now, researchers have identified a mechanism in mice that may explain the role of exposure to microbes in the development of asthma and ulcerative colitis, a common form of inflammatory bowel disease. The researchers show that in mice, exposure to microbes in early life can reduce the body's inventory of invariant natural killer T (iNKT) cells, which help to fight infection but can also turn on the body, causing a range of disorders such as asthma or inflammatory bowel disease (abstract). The study supports the 'hygiene hypothesis,' which contends that such auto-immune diseases are more common in the developed world where the prevalence of antibiotics and antibacterials reduce children's exposure to microbes."

Comments

Of course it is

[ravenspear]

Humanity (or human like creatures) survived for several hundred thousand years without modern medicine. If the body was not capable of developing defenses to disease we wouldn't still be here.

Re:Of course it is

[Anonymous Coward]

On the other hand, the average life span of human being was around 30 years in those early days at best. It is modern medicine and general quality of life that extends that to 70+ years.

Re:Sorry

[MaxEmerika]

Getting sick isn't the point. In fact, it might be exposure to relatively harmless microbes that helps stave off auto-immune disorders. The problem is that antibacterials/antimicrobials kill everything, not just the bugs that pose a threat.