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Stanford Bioengineers Create Rewritable Digital Data Storage In DNA

An anonymous reader writes "You don't hear too much about biological computing but in research published this week in the Proceedings of the National Academy of Sciences, scientists reveal they have devised the genetic equivalent of a binary digit (full article, freely available) — a 'bit' in data parlance. 'It took us three years and 750 tries to make it work, but we finally did it,' according to Jerome Bonnet, of research which describes, a method for repeatedly encoding, storing and erasing digital data within the DNA of living cells."

56 comments

  1. No more thumb drives to lose! by constpointertoconst · · Score: 4, Funny

    Sweet. This means I no longer have to worry about losing my thumb drive - I'd just plug myself in!

    Now, where should I put the pr0n folder...

    1. Re:No more thumb drives to lose! by SomePgmr · · Score: 1

      Reminds me of that Klingon from the exchange program smuggling data.. er... sensitive information off the Enterprise.

    2. Re:No more thumb drives to lose! by zlives · · Score: 1

      what kind of DRM do i have to install...

    3. Re:No more thumb drives to lose! by Anonymous Coward · · Score: 1

      Gives new meaning to the term "thumb drive"

    4. Re:No more thumb drives to lose! by mcgrew · · Score: 4, Interesting

      I was thinking of the same episode. It's weird how we've surpassed almost all of the science fiction of my youth, let alone that written before I was born. In 1966 everything in Star Trek was pure fantasy -- doors that opened all by themselves, space shuttles, talking voice-activated computers with flat screens, communicators, McCoy's sick bay (you kids can't imagine how primitive medicine was in 1966), Uhura's bluetooth earpiece... all fantasy that nobody ever expected to actually see in their lifetimes. Yet the only things from STOS we don't have today is matter replicators and warp drives.

      I live in the science fiction future of my youth!

    5. Re:No more thumb drives to lose! by Em+Adespoton · · Score: 2

      Just make sure to protect it; you wouldn't want to get a virus....

    6. Re:No more thumb drives to lose! by Anonymous Coward · · Score: 1

      We do have the MakerBot and other additive manufacturing. Granted for solids it only makes objects out of meltable materials: Plastic, metal, gelatin, wax, chocolate.

      No progress on that Warp drive though.

    7. Re:No more thumb drives to lose! by K.+S.+Kyosuke · · Score: 1

      Now, where should I put the pr0n folder...

      Most people put it into the Y folder of their 23rd chromosome pair. You know, porn being mostly (though not completely) the guy thing.

      --
      Ezekiel 23:20
    8. Re:No more thumb drives to lose! by Anonymous Coward · · Score: 0

      Now, where should I put the pr0n folder...

      Elastic Storage!

    9. Re:No more thumb drives to lose! by Anonymous Coward · · Score: 1

      "Yet the only things from STOS we don't have today is matter replicators and warp drives." .... and instant transport tech. , particle weapons (that actually work), stun rays, force field/shielding tech., instant skin+bone healing tech., cloaking technology.....
      Are you sure you remember this stuff ??

    10. Re:No more thumb drives to lose! by arth1 · · Score: 2

      "Yet the only things from STOS we don't have today is matter replicators and warp drives." .... and instant transport tech. , particle weapons (that actually work), stun rays, force field/shielding tech., instant skin+bone healing tech., cloaking technology.....

      Where are my transporter beams? Artificial gravity? Moneyless society? And blue and green ladies in spandex miniskirts...?

    11. Re:No more thumb drives to lose! by Anonymous Coward · · Score: 0

      Gee Bob! Are you glad to see me or is that an EXIF in your pants? BTW, what's that spreadsheet growing on your forehead?

    12. Re:No more thumb drives to lose! by Anonymous Coward · · Score: 0

      Did they ever debunk the 2001 setup where you just rotate everything constantly or is that an engineering problem?

    13. Re:No more thumb drives to lose! by Anonymous Coward · · Score: 0

      sorry I was talking about artifical gravity.

    14. Re:No more thumb drives to lose! by Intrepid+imaginaut · · Score: 1

      Forget all that, think about the possibilities of inherited genetic memory! Imagine being born with the knowledge of a PhD in ten different fields and being able to speak fifty languages. All we'd need is a way to access the information stored in the DNA. This may in fact become essential as the amount of time it takes to gain mastery in a field exceeds the human lifespan, as it eventually will. And each new generation could be upgraded with the achievements of the last, the technological and cultural advancements of the human race would be accelerated immensely.

      The darker side of course is implanted genetic propaganda, brainwashed from birth and unable to ever break the cycle, human robots. Thats slightly different though since its not knowledge but rather behaviour.

    15. Re:No more thumb drives to lose! by arth1 · · Score: 1

      ... but why? You'd still not land the blue and green ladies in spandex miniskirts.

  2. If you don't know... by Anonymous Coward · · Score: 0

    we sure won't help you! (we wouldn't even if you did know!)

  3. Digital storage? by Anonymous Coward · · Score: 1

    I RTFA'ed about 3 times. I'm a biologist. I don't get it. It's much more interesting from a biological perspective than a digital media perspective, where it is functionally useless. You're never going to see a "cell drive" in computers. And copying data (by cell division) can take hours.

    1. Re:Digital storage? by SpzToid · · Score: 2, Interesting

      I also RTFA'ed a few times, and so far, all I can demise is that we're screwed. Skynet wins. But then again, I Am Not A Biologist. (IANAB).

      Hawking said this would happen, btw.

      --
      You can't be ahead of the curve, if you're stuck in a loop.
    2. Re:Digital storage? by Anonymous Coward · · Score: 0

      nor a linguist. you mean "surmise"...

  4. Any word on effects by DontLickJesus · · Score: 1

    Placing pieces of data in DNA /must/ affect the creature. Any word on localizing or minimizing those effects?

    --
    Where genius and insanity become confused true wisdom is found
    1. Re:Any word on effects by LordNicholas · · Score: 3, Insightful

      Not if they're non-coding strings of DNA that aren't involved with gene expression.

    2. Re:Any word on effects by DontLickJesus · · Score: 3, Funny

      Yeah, but what's the fun in that?

      --
      Where genius and insanity become confused true wisdom is found
    3. Re:Any word on effects by bityz · · Score: 1
      The bit they are triggering is responsible for changing the color of fluorescence. From TFA:

      They used RAD to modify a particular section of DNA within microbes that determines how the one-celled organisms will fluoresce under ultraviolet light. The microbes glow red or green depending upon the orientation of the section of DNA.

    4. Re:Any word on effects by Anonymous Coward · · Score: 0

      What would the result of a format be? Not to mention partitioning...

  5. Pfft... by Anonymous Coward · · Score: 1

    ...Johnny Mnemonic was doing that 20 years ago...

    1. Re:Pfft... by zlives · · Score: 1

      haha i had the same thought

  6. Oh, so that's what it is? by Anonymous Coward · · Score: 0

    I always wondered what a "bit" was. I'm glad the summary was able to explain the "digital parlance" to me....

  7. Johnny Mnemonic by ClosedEyesSeeing · · Score: 1

    So, when do I start getting paid to carry people's data around in my head?

    1. Re:Johnny Mnemonic by Anonymous Coward · · Score: 0

      So, when do I start getting paid to carry people's data around in my head?

      As soon as you land a job and move out of your parents' basement.

  8. The last piece! by FreedomOfThought · · Score: 1

    Finally! I can make my Artificial Intelligence algorithms into a living thing!

  9. Finally! by aglider · · Score: 2

    I can backup my BDs in my urine and feces!

    --
    Sent as ripples into the electromagnetic field. No single photon has been harmed in the process.
  10. 2fer on viruses by CoderFool · · Score: 5, Insightful

    This digital data storage could get both technological and biological viruses! I wonder what the crossover will be like... You thought bird flu jumping to pigs then humans was bad....

    1. Re:2fer on viruses by TheInternetGuy · · Score: 1

      This digital data storage could get both technological and biological viruses! I wonder what the crossover will be like... You thought bird flu jumping to pigs then humans was bad....

      Yeah I know, the Symantec stock just jumped like giddy old mare.

      --
      If my comment didn't sound as good in your head as it did in mine, then I guess we all know who's to blame
  11. Kilroy 2.0 ... by Anonymous Coward · · Score: 0

    is Everywhere!
    John Alpha already used this technology!!

  12. So what does that mean for our 'junk' DNA? by Anonymous Coward · · Score: 0

    So what if this has been done before already?

    From this article:
    http://www.psrast.org/junkdna.htm

    More than 98 percent of all DNA, was called "Junk DNA" by molecular biologists, because they were unable to ascribe any function to it. They assumed that it was just "molecular garbage". If it were "junk", the sequence of the "syllables", i.e. the nucleotides in DNA should be completely random.

    However it has been found that the sequence of the syllables is not random at all and has a striking resemblance with the structure of human language (ref. Flam, F. "Hints of a language in junk DNA", Science 266:1320, 1994, see quote below). Therefore, scientists now generally believe that this DNA must contain some kind of coded information. But the code and its function is yet completely unknown.

    1. Re:So what does that mean for our 'junk' DNA? by PhilHibbs · · Score: 1

      Assuming that "junk dna" would be random is like assuming that the junk mail in my bin is just random letters of the alphabet.

    2. Re:So what does that mean for our 'junk' DNA? by Anonymous Coward · · Score: 0

      The analogy is bad. Junk mail is written by an intelligent person. If "junk dna" is truly junk DNA, with no evolutionary advantage or disadvantage, I'd expect random mutations to make it random DNA over time. this presuposes that it is truly not impacting evolutionary success one way or another and a long time period. But it is what I'd expect.

  13. Copyright infringment! by bityz · · Score: 1
    From the article

    Bonnet has now tested RAD modules in single microbes that have doubled more than 100 times and the switch has held. He has likewise switched the latch and watched a cell double 90 times, and set it back. The latch will even store information when the enzymes are not present. In short, RAD works. It is reliable and it is rewritable.

    When the microbes double, the bit is copied. Just wait until the RIAA finds out!

  14. Slowest data storage ever by Latinhypercube · · Score: 1

    And it only takes a week to write 8 bits of data

    1. Re:Slowest data storage ever by bityz · · Score: 1
      According to TFA, this is a single reliable bit.

      So far they can only write one bit eight times.

    2. Re:Slowest data storage ever by Em+Adespoton · · Score: 1

      Yes... but then all they need is another microbe where they can't write that bit. String them together to get your storage. Replicate ad nauseam....

    3. Re:Slowest data storage ever by bityz · · Score: 1

      true, now we just need a way to order the microbes

  15. Bandwidth by TuringTest · · Score: 2

    a 'bit' in data parlance. 'It took us three years and 750 tries to make it work, but we finally did it'

    There, and I thought my ISP's bandwitdh was awful.

    --
    Singularity: a belief in the "God" idea with the "demiurge" relation inverted.
  16. Hmm by Anonymous Coward · · Score: 0

    I feel that this is the first step towards integrating with the Zerg Hive.

    Rush! Kekekekekekekekekekekeke.

  17. Blood Music by Brannoncyll · · Score: 3, Interesting

    This reminds me of a fantastic book called Blood Music by the science fiction author Greg Bear. In the book a geneticist working on biochip development develops a system for storing and transmitting information between single cells using DNA and RNA. He creates cells that are able to communicate and incorporate elements of RNA and as such optimise themselves to overcome environmental challenges. He soon sees the emergence of rudimentary intelligence on a cellular basis, but is shut down before he can pursue his experiments further. He smuggles his creations out of the lab by injecting them into his own body, which proves to be a perfect environment for the development of full intelligence....

    1. Re:Blood Music by Anonymous Coward · · Score: 1

      erm... sci-fi? Ever heard of http://en.wikipedia.org/wiki/Bacterial_conjugation as an example of horizontal transfer of genetic information? It's real and it's one of the reason we have major trouble with resistent super bacteriae like O/MRSA and VRE.

    2. Re:Blood Music by Anonymous Coward · · Score: 0

      The one of the broadest definitions of 'science fiction' is 'fiction with science as the subject'.

      The sciencey bits don't have to be perfectly fictional. It's okay.

  18. Stargate Goa'uld by Anonymous Coward · · Score: 0

    Demonstration of genetic memory concept of the Goa'uld from Stargate?

  19. Neat by HeckRuler · · Score: 1

    So how long before we get a driver that can turn this data into biological functions? Say, over-riding the optical and aural sensors on demand.
    I want to be able to rickroll my grandchildren. DAILY.

  20. interesting by Anonymous Coward · · Score: 0

    Maybe they could bio engineer a smart slash dot poster, one that doesn't have to put their politics into everything. One that doesn't bash the US every chance they get and think its funny saying things like faux news, like every news site is honest in America isn't hell bent on some agenda? One that doesn't constantly bash capitalism while collecting a check made from profits. Or maybe one who stops comparing the Tea party to nut cases while holding up OWNS as non criminals. Hell even a smart one who doesn't believe in the great Global Warming religious scandal lie?

    1. Re:interesting by xevioso · · Score: 1

      Except that all those things are true.

  21. Does this mean I need to buy the Beatles again? by Anonymous Coward · · Score: 0

    Damn it.

  22. Star Trek NG by nickmalthus · · Score: 2

    This article reminds me of the STNG episode "The Chase"

    --
    If a nation expects to be ignorant and free, in a state of civilization, it expects what never was and never will be-T J
  23. Great ... for illegal pissers! by freaker_TuC · · Score: 1

    Pissing in a cup will show traces of illegal content usage!

    Those downloading movies and music in their DNA, think twice ..

    --
    --- I am known for the ones who want to find me on the net. Is that a privacy risk or a privilege? One might wonder..