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Scientists Turn Skin Cells Into Beating Heart Muscle

An anonymous reader writes "By taking skin cells and turning them into stem cells, a technique that is already well known, researchers at Technion Israel Institute of Technology were able to generate beating heart cells — a medical first. 'We have shown that it's possible to take skin cells from an elderly patient with advanced heart failure and end up with his own beating cells in a laboratory dish that are healthy and young — the equivalent to the stage of his heart cells when he was just born,' Lior Gepstein, study author and professor of medicine said."

11 of 121 comments (clear)

  1. A question for the bio geeks.. by wbr1 · · Score: 4, Interesting

    By taking skin cells and turning them into stem cells as the precursor to other cell lines that match the patients genetic makeup. are you increasing the chances of cancer?
    In my certainly uninformed view, skin cells are exposed to more radiation, thus more likely to have replication errors in their DNA, then adding the stress of modifying the cell to another form, I wonder what that does to it from a replication standpoint. It is nice to have fresh heat muscle I am sure, but to suddenly find yourself with melanoma in the heart would be a bummer.

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    1. Re:A question for the bio geeks.. by cvtan · · Score: 4, Funny

      That means you could literally make a politician out of a horses ass!

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    2. Re:A question for the bio geeks.. by Kurofuneparry · · Score: 5, Informative

      Biochemist medical student here. Propagating genetic errors is certainly a concern here, but the same concerns exist for genetic transfer in breeding generally. While skin cell are exposed to more radiation, the cells preferred for sampling here are typically from buccal (mouth) sources or are relatively deeper than the layers where most melanoma form.
      Honestly, the more prime concerns are with imperfect "stemming" or imperfect conversion to heart cells.
      Then again ... I'm and idiot ....

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    3. Re:A question for the bio geeks.. by geekoid · · Score: 5, Insightful

      No.

      If it were true, so what? You need a heart replacement or you will die, soon. If the procedure might give you cancer in 20 years, isn't that still a good trade?

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    4. Re:A question for the bio geeks.. by RabidReindeer · · Score: 4, Insightful

      That means you could literally make a politician out of a horses ass!

      That's just a circular exercise. You end up with the same thing you started with.

    5. Re:A question for the bio geeks.. by ColdWetDog · · Score: 4, Informative

      At any rate, this is early on in the program. Nobody is making new hearts just yet. Cancer certainly is an issue but only one of many potential problems.

      The abstract in case anybody cares. The real article is behind the usual paywall. Grrr.

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  2. Re:immortality by Anonymous Coward · · Score: 5, Insightful

    Over population is a problem ...

    Overpopulation is not a problem. That is a myth that has been perpetuated since the latter half of the 18th century. Do the math.

    Only problem is, you can replace everything in the body except the brain.

    Perhaps even the brain... someday. There's nothing inherently mystical or supernatural about the brain that must make it impossible to transfer knowledge and identity from one to the other. We just don't know how... yet.

    I see a future of hybrid human technology species

    Without a doubt. I anticipate that it will start becoming a regular occurrence for people to augment their physical and even mental abilities with machines well before the end of this century.

  3. Re:More of this, please by WillDraven · · Score: 4, Interesting

    Personally, I'm hoping that we get back on track with space travel, and then I can upload myself into an interstellar space probe. If nano-tech gets good enough, you could maybe even reconstitute a physical body if you find someplace interesting to land. With an electronic mind, you could alter your perception of time so the boring parts of floating between stars for years would only last a few minutes subjectively.

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  4. Re:More of this, please by Spiked_Three · · Score: 4, Funny

    My head is ugly. I want all new please.

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  5. Re:Where's George Bush? by Spiked_Three · · Score: 4, Funny

    they cloned him as Mitt Romney and he is on the way, patience.

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  6. Re:More of this, please by Adriax · · Score: 4, Funny

    The toggle for the host computer's perception speed had better resemble a 386SX-16 turbo button or I wouldn't even bother.

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