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Scientists Move Closer To a Universal Flu Vaccine

Hugh Pickens writes writes "Vaccines for most diseases typically work for years or decades but with the flu, next fall it will be time to get another dose. Now Carl Zimmer writes that a flurry of recent studies on the virus has brought some hope for a change as flu experts foresee a time when seasonal flu shots are a thing of the past, replaced by long-lasting vaccines. 'That's the goal: two shots when you're young, and then boosters later in life' says Dr. Gary Nabel, predicting that scientists would reach that goal before long: 'in our lifetime, for sure, unless you're 90 years old.' Today's flu vaccines protect people from the virus by letting them make antibodies in advance but a traditional flu vaccine can protect against only flu viruses with a matching hemagglutinin protein. If a virus evolves a different shape, the antibodies cannot latch on, and it escapes destruction. Scientists have long wondered whether they could escape this evolutionary cycle with a universal flu vaccine that would to attack a part of the virus that changes little from year to year so now researchers are focusing on target antigens which are highly conserved between different influenza A virus subtypes. 'Universal vaccination with universal vaccines would put an end to the threat of global disaster that pandemic influenza can cause,' says Dr. Sara Gilbert."

4 of 205 comments (clear)

  1. Vaccines !=drugs by Kupfernigk · · Score: 0, Offtopic
    You are confusing completely different things. Vaccines have generally been extremely safe and effective, despite some arseholes trying to spread fud about them for commercial gain (you can easily find who I mean). Drugs...recent drugs have tended to be ineffective and a lot has been spent on dodgy trials and high pressure salesmanship.

    Having said that I was laid out for two days solid by this year's flu vaccine and really would like to see a better one.

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    From scarped cliff or quarried stone she cries "A thousand types are gone, I care for nothing, no not one."
  2. Re:good vaccine by bertok · · Score: 1, Offtopic

    exercise and vitamins and good food.

    Oh good, advice from a Slashdot armchair physician.

    Unfortunately, what you don't know can quite literally kill you: the influenza virus can do more damage to young healthy people than the infirm, and some strains infect over 30% of the population, irrespective vitamin pills or yoga classes.

    Read up on the 1918 flu pandemic and then cytokine storms to gain a glimmer of understanding into why research into a flu vaccine is more important than almost any public safety measure you can think of. Short of nuclear war, there's not a lot of things that are likely to wipe out a significant fraction of the human race, but the flu is one of them. We're practically overdue for a strain deadly enough to kill more people in a year than WWI and WWII combined.

    I'd like to see you try to keep your attitude towards healthy living as the best defense against a viral plague when the government starts hauling away the bodies of your neighbors by the truckload.

  3. In related news.. by Drathos · · Score: 1, Offtopic

    This just in! Nature moves closer to a flu immune to the "universal" vaccine.

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    End of line..
  4. Re: Gladly by Anonymous Coward · · Score: 0, Offtopic

    The DOD's anthrax vaccine scandal comes to mind. Funny how the owner of Biport, a big Clinton donor, was able to get his plant reopened after the FDA closed it.