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HIV Vaccine Safe Enough To Pass Phase 1 Human Trials
An anonymous reader sends this excerpt from Western University in Canada:
"The first human applied clinical study (SAV CT 01) using a genetically modified killed whole-virus vaccine (SAV001-H) to evaluate its safety and tolerability was initiated in March 2012. This study is a randomized, observer-blinded, placebo-controlled study of killed whole HIV-1 vaccine (SAV001-H) following intramuscular (IM) administration. Infected men and women, 18-50 years of age, have been enrolled in this study and randomized into two treatment groups to administer killed whole HIV-1 vaccine (SAV001-H) or placebo. Sumagen announced today the patient enrollment has progressed smoothly and there have been no adverse effects observed including local reactions, signs/symptoms and laboratory toxicities after SAV001-H injection in all enrolled patients to date. With these interim results, the SAV001-H has proven safety and tolerability in humans and given Sumagen confidence for the next clinical trials to prove its immunogenicity and efficacy evaluation."
Along with the anti-vaccine nutters?
Clearly using real HIV viruses must be very risky and dangerous
Don't want first post on the sign up list.
That I can tell women that I have the AIDS vaccine at the bar, and can give it to them through intra-muscular administration.
It is not found in mankind prior the last 100 years.
The test for HIV tests for antibodies... So the human body already makes antibodies against HIV... So how are the antibodies for this vaccine different? *These* work? How?
I find it interesting that all the subjects were already HIV positive. It looks like this study only shows that it is ok to inject into a human, not that it does anything useful.
Why is a vaccine useful to (and being tested on) someone already infected?
How exactly does one year of study validate the prevention of such a slowly progressing disease?
Has anyone found any details on the genetic modification. Because ... HIV is not alive, a virus is only a blueprint for itself, which the cell starts to copy. And this copying process than leads to side effects depending on what the virus information contains - the symptoms.
So a "whole virus" that is "killed" is plain nonsense.
And as there are only extremely rare cases where there are therapeutically relevant anti-HIV antibodies ever (usually the restriction is T cell based or CCR5 mutations) ... a vaccine that is supposed to induce antibodies with a full virus makes no sense whatsoever.
They're testing whether or not it's safe, not whether it will be effective.
I hear it can cure you of HIV, but then makes you gay. You then get AIDS and die. It's deadly, bro.
It's a feature!
Do it yourself, because no one else will do it yourself. [beta blockade 10-17 Feb]
dont stick your penis in an unknown and untested wet hole.... or a used needle into your body. quite easy and cheap isnt it?
This isn't rocket science people
Hmm, this will inevitably lead to a second population explosion in Africa.
This whole subject is a complete hoax. HIV / AIDS are political -- not medical -- diseases targeted at getting "undesirable" segments of the population to ingest expensive and deadly chemicals marketed as pharmaceutical drugs.
For more information, visit http://tinyurl.com/am8v2w4
There are *lots* of HIV vaccines in development, many reaching phase I and others going further. There's even one recent phase III showing some evidence of a preventative effect.
For a review check: http://www.ncbi.nlm.nih.gov/pubmed/22710904
I'm going to cheer for these folks.
It's been almost 20 years since i lost friends. :-(
I'm here for the experience, not the Hyperbole.
From Sumagen's website:
"Sumagen’s HIV/AIDS vaccine is also supported for its R&D cost from the HIV/AIDS vaccine development fund, jointly launched by the Bill and Melinda Gates Foundation and the government of Canada."
This is what it should say, "not an anonymous reader writes". Another one of those paid pharma stories and
this is not even the target segment, the world knows Slashdot Geeks don't get laid ever. Anyhow most of Geeknet's
business is to place paid for articles on sites they own such as slashdot and this is what happened
As far as the 'vaccine' itself is concerned, be my guest let them shoot you up with this crap I will not give you a
cent when I see you begging at the traffic light because of all the neurological damage it dealt you.
There is no (Canadian) Western University. It's the University of Western Ontario, sometimes called "Western" for short, but never Western University. It's also only western if you're from southern Ontario since its actually located in the south east corner of the province.
If you will fuck anything that moves and says yes - well you are engaging in risky behavior.
Definitely. The low-risk choice is to find something that says no, then make it stop moving.
I'll just give you a personal example. My brother lost his job. As a result, he was unable to pay child support. This means he can't register his car or have a professional license. (think "home contractor" or "termite services" or "lock smith" or "welder", depending on the state) OK, so how exactly is he supposed to get a job? Was the intent to prevent him from ever recovering?
Furthermore, why does she get to decide anyway? I don't know if he wanted an abortion, but why wouldn't he get equal rights? The playing field is not remotely level here. Fairness demands that she accept full financial responsibility if she chooses to keep the child.
Unfairness in the courts is self-evident when you look at who tends to get custody and who tends to file for divorce. It's nearly all women. Men don't often file for divorce, even when they hate the lady, because men know they will lose and lose and lose. Women file because they know they will win.
If this problem hasn't already hit somebody you care about, consider yourself lucky... for now. Your blissful ignorance is unlikely to last a lifetime.
I mean when you see we got bin laden thru such a vaccination program... That does not help cement the trust into doctors.
Yeah, that ought to be enough. Let's rush it through before any long-term effects get noticed.
Search Dr Sebi on youtube, he had been curing cancer for more than a decade just by herbs.
Spending money on things like this is a waste. HIV is a harmless virus that has existed in humans at least 100 years before AIDS started killing us off in the 80s. AIDS drugs actually do more to cause AIDS than HIV which does nothing especially since your body developes antibodies as soon as you're infected making it dormant at the worst.
You want to get rid of HIV and other disease, then you'll have to wait for National Health Care since your inusrance isn't going to pay for it.
I don't think they understand what a vaccine is?
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Stay tuned for some shock and awe coming right up after this messages!