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Scientists Grow Replacement Human Teeth In Mouse Kidneys

sciencehabit writes "When an adult loses a tooth, there's no hope of growing a new one—unless you've got a mouse kidney handy. In a new study, researchers injected human gum tissue extracted during oral surgery into the molars of fetal mice. After giving the cells a week to get used to each other, the scientists implanted the chimeric concoction into the protective tissue surrounding the kidneys of living mice. There, 20% of the cells developed into objects recognizable as teeth, complete with the root structures missing from artificial tooth implants. The next step is to transplant these so-called 'bio-teeth' back into human mouths and see if they grow into something that we can chew on—or rather, with."

6 of 117 comments (clear)

  1. They wash them by i+kan+reed · · Score: 5, Funny

    No need to worry about how gross that sounds, they wash them before putting them in, using a special sterilizing soap grown from a rat's testicles.

    1. Re:They wash them by tippe · · Score: 4, Funny

      Nicholson [pointing a gun at DiCaprio]: I taste a rat!
      DiCaprio: Those are you're new implants, boss!
      Nicholson [putting gun away]: Oh yeah. It's going to take some time to get used to these...

  2. Really, a fake tooth is fine, thanks by Anonymous Coward · · Score: 4, Funny

    As tempting as putting something in my mouth grown from a mouse's kidney sounds, I'll just take a crown or some bridgework, thanks.

  3. It sounds good but by Chrisq · · Score: 5, Funny

    It sounds good but the instruction was to grow human kidneys in rats teeth. It was a real Do'h moment when the researcher reread his brief!

  4. Re:Why not just grow it in our mouth. by Mystakaphoros · · Score: 5, Funny

    My guess is that it's a little easier to euthanize a mouse when something goes horribly, horribly wrong.

  5. Re:Why not just grow it in our mouth. by saveferrousoxide · · Score: 4, Funny

    I don't know...maybe it's just me, but teeth growing out of my kidney sounds like something gone horribly, horribly wrong...