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Activity of Whole Fish Brains Mapped Second To Second

ananyo writes "Researchers have imaged an entire vertebrate brain at the level of single neurons for the first time. A team of scientists based at the Janelia Farm Research Campus in Ashburn, Virginia, were able to record activity across the whole brain of a fish embryo almost every second, detecting 80% of its 100,000 neurons. The work is a first step towards mapping the activity of a whole human brain — which contains about 85,000 times more neurons than the zebrafish brain. The imaging system relies on a genetically engineered zebrafish (Danio rerio). The fish's neurons make a protein that fluoresces in response to fluctuations in the concentration of calcium ions, which occur when nerve cells fire. A microscope sends sheets of light rather than a conventional beam through the fish's brain, and a detector captures the signals like a viewer watching a cinema screen. The system records activity from the full brain every 1.3 seconds."

3 of 56 comments (clear)

  1. Fish's last thought recorded by Grayhand · · Score: 5, Funny

    "Oh look, a hook!"

    1. Re:Fish's last thought recorded by Anonymous Coward · · Score: 4, Funny

      in case someone thinks i'm serious about fish thinking deep thoughts

      Admittedly lab aquariums are pretty shallow, but some fish live and think a kilometre below sea level. Those are some pretty deep thoughts.

  2. Re:Obviously.. by MachDelta · · Score: 3, Funny

    Let me guess... Linux user?