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New Links Found Between Bacteria and Cancer

Shipud writes "A recent study by a group at the University of Maryland School of Medicine shows that bacterial DNA gets transferred to human cells, in a process known as lateral gene transfer, or LGT. LGT is known to occur quite commonly between bacteria, including bacteria of different species. In fact, that is how antibiotic resistance is transferred so quickly. The team has shown that certain types of tumor cells acquire bacterial DNA that may play a role in tumor progression. Another group at the University of North Carolina, Chapel Hill has shown that gut inflammation leads to a radical change in the microbial population there, which encourages growth of E. coli that can disrupt the inflamed cells' DNA, leading to cancer. Both studies enable us to ask new questions such as: how does inflammation change the landscape for bacterial colonization? Can bacteria indeed harness inflammation — and then cancer — to flourish and remove competitors from their newly found ecosystem? And can we use this information to fight cancer?"

3 of 159 comments (clear)

  1. lateral transfer / evolution by davids-world.com · · Score: 3, Interesting

    Oh, thanks. I've just learned something. I have used resistance to antibiotics as an example of real-time observable evolution. If it is actually lateral transfer, then this example won't hold. Good to know!

    1. Re:lateral transfer / evolution by Anonymous Coward · · Score: 2, Interesting

      The genes for resistance still have to be evolved by some bacterium. The gene transfer just helps with spreading those genes far and wide.

    2. Re:lateral transfer / evolution by Anonymous Coward · · Score: 2, Interesting

      That's interesting. So maybe if a woman has children from two men, the second child may end up having some DNA from the father of the first, passed through the mother.