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Is the World's Largest Virus a Genetic Time Capsule?

gbrumfiel writes "Researchers in France have discovered the world's largest virus and given it a terrifying name: Pandoravirus. NPR reports it doesn't pose a threat to people, but its genetic code could hint at an unusual origin. The team believes that the virus may carry the genes from a long-dead branch of the tree of life, one that possibly even started on Mars or somewhere else. Other scientists are skeptical, but everyone agrees that the new giant virus is pretty cool."

30 of 111 comments (clear)

  1. Just a little by Anonymous Coward · · Score: 2, Insightful

    The team believes that the virus may carry the genes from a long-dead branch of the tree of life, one that possibly even started on Mars or somewhere else.

    Other scientists are skeptical

    No shit? That's one heck of an extraordinary claim right there. It'd be very fascinating if true, but that's going to need some strong evidence backing it. Either way, a virus of its size is still quite interesting.

    1. Re:Just a little by Samantha+Wright · · Score: 5, Informative

      This kind of questioning showed up when the Mimivirus, the first (?) giant amoeba virus appeared, including the bit about degenerating into a virus as a survival strategy. It turned out that all of its genes came directly from the amoebae it was infecting; it's basically just really bad at reproducing. While it would be really neat to discover the remnants of a lost superphylum or kingdom, viruses mutate much too quickly for any informative signal to be preserved.

      The reality is that we've only sequenced a tiny fraction of the Earth's biodiversity. There's a lot of stuff out there that's just more of the same, especially at the microbe level. The farther back you go, the lower the likelihood of finding a surviving isolate, which is why isolated biomes like Lake Vostok and the drilling site in Northern Ontario are so important.

      --
      Bio questions? Ask me to start a Q&A journal. Computer analogies available for most topics!
    2. Re:Just a little by icebike · · Score: 3, Insightful

      The team believes that the virus may carry the genes from a long-dead branch of the tree of life, one that possibly even started on Mars or somewhere else.

      Other scientists are skeptical

      No shit? That's one heck of an extraordinary claim right there. It'd be very fascinating if true, but that's going to need some strong evidence backing it. Either way, a virus of its size is still quite interesting.

      Dna in the virus. Composed of the same nucleotides found in all life on earth.
      So either all life on earth originated on mars (or somewhere), or these viruses originated on earth.

      One case makes them simply interesting, the other makes for much better headlines and vastly more grant money.

      --
      Sig Battery depleted. Reverting to safe mode.
    3. Re:Just a little by jamesh · · Score: 3, Interesting

      The team believes that the virus may carry the genes from a long-dead branch of the tree of life, one that possibly even started on Mars or somewhere else.

      Other scientists are skeptical

      No shit? That's one heck of an extraordinary claim right there. It'd be very fascinating if true, but that's going to need some strong evidence backing it. Either way, a virus of its size is still quite interesting.

      Easy to prove. Just compare the genetic material in the virus to all the other life we've found on Mars (or somewhere else).

    4. Re:Just a little by nine-times · · Score: 3, Insightful

      Reading the article, I'm not sure if the scientist made the claim:

      That life could have even come from another planet, like Mars. "At this point we cannot actually disprove or disregard this type of extreme scenario," he says.

      So it seems like maybe the reporter posits that it came from Mars, and the scientist said, "Well we can't disprove that right now."

    5. Re: Just a little by jbengt · · Score: 2

      Most viruses do carry RNA. But I believe retroviruses carry RNA also, and use reverse transcriptase to make DNA from the RNA, and then use regular transcription to make RNA for the virus. Retroviruses are just about impossible to get rid of if they integrate the DNA they make into the host genome along the way. According to Wikipedia, DNA viruses that first make RNA in the cell and then use reverse transcriptase to make DNA for the virus are called pararetroviruses.

    6. Re:Just a little by RDW · · Score: 3, Informative

      It's a bit more complicated than that:

      https://en.wikipedia.org/wiki/Baltimore_classification

  2. Macrovirus? by EzInKy · · Score: 2

    Is it as large as this one?

    --
    Time is what keeps everything from happening all at once.
    1. Re:Macrovirus? by Samantha+Wright · · Score: 2

      I always thought those looked more like diatoms, though I guess that doesn't sell as well.

      --
      Bio questions? Ask me to start a Q&A journal. Computer analogies available for most topics!
    2. Re:Macrovirus? by EzInKy · · Score: 3, Funny

      There is a difference?

      --
      Time is what keeps everything from happening all at once.
  3. "Pretty cool" !! by ze_jua · · Score: 2

    I agree with this judgment. It's precise, explicit. Scientific. I find that the LHC and the ISS are pretty cool stuff :-)

  4. One micrometer by Kwyj1b0 · · Score: 2

    It should have been in the summary, but the virus is about a micrometer in length. Which is cool, and huge. Just imagine - a a group of a few thousand, and it becomes visible to the naked eye.

    1. Re:One micrometer by TapeCutter · · Score: 3, Interesting

      Coincidentally, there was a Brian Cox doco on last night that mentioned the world's smallest insect, a wasp that measures 0.4mm, my 54yo eyes couldn't detect them but he described them as "very fine specs of dust". So a rough estimate says a young pair of eyes could pick out a group of less than 500 individuals. According to the same doco, if you exclude viruses from the tree of life then there is roughly 22 orders of magnitude between the largest trees and the smallest microbes. Basically the megavirus and wasp's sizes are less than three orders of magnitude apart, which is quite incredible since I'm used to thinking of viruses as basically large molecules (IIRC the smallest known viruses are composed of a mere 10,000 atoms).

      --
      And did you exchange a walk on part in the war for a lead role in a cage? - Pink Floyd.
  5. discovered a the worst editing by mirix · · Score: 2

    "Researchers in France have discovered a the worlds largest virus and given it a terrifying name: Pandoravirus.

    We can't even have the first sentence of a submission checked now?

    --
    Sent from my PDP-11
    1. Re:discovered a the worst editing by wonkey_monkey · · Score: 3, Insightful

      Well, you didn't spot the lack of an apostrophe in "worlds." Maybe editing is tougher than it looks ;)

      --
      systemd is Roko's Basilisk.
  6. Hoip! by CuteSteveJobs · · Score: 3, Insightful

    Another example of how great marketing helps get your research funded. The reason this is being widely reported is because they chose a cool name. Pandoravirus. But how does Pandora's box come into this? When it comes to viruses bigger is lamer so size doesn't matter. It is not a threat to people nor anyone else except amoebas. The origins speculation is interesting, but this whole thing is being hyped up by the researchers. And possibly by the amoebas.

  7. Best read with a Thomas Dolby intonation by Empiric · · Score: 5, Funny

    ... one that possibly even started on Mars or somewhere else.

    Science.

    --
    ~ Whence do you come, slayer of men, or where are you going, conqueror of space?
  8. Re:In Soviet Russia... by cold+fjord · · Score: 5, Funny

    Try this one instead: In Soviet Russia, box of Pandoravirus opens you.

    --
    much of left-wing thought is a kind of playing with fire by people who don't even know that fire is hot - George Orwell
  9. Pandoravirus isn't such a terrifying name by Anonymous Coward · · Score: 4, Funny

    I think if you wanted to really terrify people, you'd name it Pandora's Pox.

  10. "Terrifying Name" May Not Be So Intended by cervesaebraciator · · Score: 3, Informative

    Pandora is a Greek compound meaning all gifts (pan, as in pantheon--all the gods + dora, pl., as in Theodore--a gift of God). Just an FYI. I'd give the actual Greek but, alas, unicode support on /. does not have the greatest reputation. I see the term thrown about in literature sometimes, and I the think intent can be missed because folks only know the story from Hesiod. I suspect this is what Cameron had in mind when he thus christened the planetary home of his Lakota, er, Powhatan's Algonquin, ah... no, Na'vi, yeah that's what he called the sympathetic characters in his highly original film.

    1. Re:"Terrifying Name" May Not Be So Intended by gl4ss · · Score: 2

      it's greek gods. they're all sons of bitches and pranksters. they torture whistleblowers and play with human destinies for shits'n'giggles, so gifts from them...

      --
      world was created 5 seconds before this post as it is.
  11. Re:In Soviet Russia... by Anonymous Coward · · Score: 2, Insightful

    I was thinking more of a Soylent Green paraphrasing with preachy environmentalist overtones:

    "It's people. The world's largest virus is people."

  12. Competing theories by Camael · · Score: 4, Insightful

    From TFA. The discoverers:-

    "We believe that those new Pandoraviruses have emerged from a new ancestral cellular type that no longer exists," he says. That life could have even come from another planet, like Mars. "At this point we cannot actually disprove or disregard this type of extreme scenario," he says.

    The naysayers :-

    The virus's size is probably part of its survival strategy. Amoebas and other simple creatures could mistake it for bacteria and try to eat it, opening them up to infection. "The internal environment of the amoeba cell provides a very good playground for acquiring various kinds of genes from different sources," Koonin says. He thinks that the Pandoravirus's unusual genome may be a mishmash of random genetic material it's sucked up from its hosts.

    I cite Occam's Razor -the simplest explanation is usually the correct one. Apologies to the discoverers, but I think its far too early to point to any "ancestral cellular type that no longer exists".

  13. Re:Small threat to people? by cnettel · · Score: 2

    The article, as in scientific paper, is quite clear on this. There is no signs that anything close to vertebrates are infectable.

  14. This is old news by shikaisi · · Score: 4, Funny

    The world's largest virus was discovered a long time ago. It's called Windows 8.

    --
    No left turn unstoned.
    1. Re:This is old news by Anonymous Coward · · Score: 2, Funny

      I found an old Windows ME box in Lake Vostok.

  15. Re:In Soviet Russia... by ubersoldat2k7 · · Score: 3, Funny

    In NSA America world's largest virus discovers YOU!

  16. Re:Mars? by jamesh · · Score: 2

    Most likely this virus has come from the oceans' depths...

    ... of mars.

  17. Mimiviruses, related to what? by __aaltlg1547 · · Score: 2

    Summary is misleading. It's not just one species of virus. The article abstract says they found TWO species of these Pandoraviruses. The "possibly started on Mars" is just hype. There's exactly zero evidence of that.

    I suspect that in the long term, they'll find abundant evidence that they're related (perhaps not closely) to every other kind of life on Earth. Especially since they are viruses. Viruses can only target particular species of cells and would quickly become extinct in the absense of those species. How could they evolve the ability to infect Earth life on Mars? That makes no sense. If something was going to make it here from another planet and establish itself in our ecosphere, it wouldn't be viruses or any other species that depends on the presence of some particular species already being here.

  18. Am I the only smart person on this thread? by betterprimate · · Score: 2

    I was the first one to read this story and point out the real hypothesis.... test it mother fuckers... I dare you.... I am *never* been wrong. You incompetent assholes make careers out my pastimes.
     
    I got down modded twice as redundant because some asshat says exactly the same as me. Fuck off you dumb motherfuckers. No one gave as much insight as I had. You stupid pieces of shit. I'm done dealing with /. Bunch of fucking stupid monkeys in a barrel.