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Cells Reprogrammed In Living Mice
sciencehabit writes "Researchers have discovered a surprisingly effective way to 'reprogram' mature mouse cells into an embryolike state, able to become any of the body's cell types (abstract). Their recipe: Let the transformation happen in a living animal instead of a petri dish. The finding could help scientists better understand how reprogramming works and it may one day help breed replacement tissues or organs in the lab—or in living patients."
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Morphing cells, so, this can have the amazing implication of fixing pretty much anything, if not enhancing and/or even modifying your cells.. Can this help with aging?
Their recipe: Let the transformation happen in a living animal instead of a petri dish.
I was under the impression that it is fairly common knowledge that cells from multicellular animals have difficulty surviving (and even more difficulty behaving) when not in such an animal. Maybe I only remembered the cases where attempted cell cultures from [test animal] failed to survive at all in dishes.
I can see why this sort of test is not the first choice, science is cleaner the fewer unknown variables are involved. On the other hand, biochemistry is very complex, and I'm not exactly surprised that some of these experiments work when in the setting of a living animal even if they cannot in a controlled environment.
My conclusion: Good progress, keep testing, and try not to make tumors.
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Could be messy, but ultimately, would a 'rolling regeneration' of our organs conveniently sidestep cellular senescence? Can you hear me now?
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If they can figure out how to reprogram fat cells to be muscle cells, we can eat McD's for an entire month end up looking like Arnold Schwarzenegger.
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true regeneration. It's that simple. If you can literally reprogram your cells, then you can use this for maintenance and/or repairs. Certainly this can mean cutting to the quick when it comes to issues such as aging. This is literally a gold mine. If such knowledge can become applied in a practical way, this can become real preventive medicine. It would have the ability to halt aging. It would also have the ability to regenerate any part of us we have, thus eliminate the need for organ donors. As long as the human brain is well, this could more than likely make us rethink our entire way we deal with medicine. This can become a big deal.
More than meets the eye!