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First 3D Printed Liver Expected In 2014

Posted by samzenpus on from the drink-up dept.

Lucas123 writes "After 3D printing has produced ears, skin grafts and even retina cells that could be built up and eventually used to replace defective eye tissue, researchers expect to be able to produce the first functioning organ next year. The organ, a liver, would not be for the purpose of human implant — that will take years to complete clinical trials and pass FDA review. Instead, the liver would initially be for development and testing of pharmaceuticals. The field of 3D printing known as organs on a chip, will greatly increase the accuracy and speed of drug development and testing, researchers say. The company producing the liver, Organovo, has overcome a major stumbling block that faces the creation of any organ: printing the vascular system needed to provide it with life-sustaining oxygen and nutrients. Typically, 3D printed tissue dies in the petri dish before it can even be used because of that. 'We have achieved thicknesses of greater than 500 microns, and have maintained liver tissue in a fully functional state with native phenotypic behavior for at least 40 days,' said Mike Renard, Organovo's executive vice president of commercial operations."

8 of 67 comments (clear)

  1. Good by Hamsterdan · · Score: 4, Funny

    Now, how long we /.ers can print a wife?

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    I've got better things to do tonight than die.
    1. Re:Good by Thanshin · · Score: 3, Informative

      Because Preview.

    2. Re:Good by Jawnn · · Score: 3, Funny

      Why would you print out the whole thing?

  2. Fantastic! by adolf · · Score: 5, Funny

    3D printed livers?

    Bottoms up, mates!

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    Kid-proof tablet..
    1. Re:Fantastic! by MrLizard · · Score: 3, Informative

      It's possible each layer printed can seamlessly connect to the next layer, given appropriate nutrients/conditions. I believe (bio class was a long time ago; I think it was when they were still teaching about the humours) that cells can communicate chemically and tell other cells, "hey, join up here". If all the correct cell types are in the mix, each layer should link up to form the necessary structures, especially if the focus is replacing damaged portions of an organ and not building the whole thing as one big lump.

      It's too soon to say "Cirrhosis, shmirrohsis, I'll just buy a new liver at Wal-Mart[1]", but this step forward seems far from impractical.

      [1]More socially-conscious types may prefer to shop at neighborhood businesses that produce locally-sourced organs printed using fair labor practices. But you'll pay more, and they're not open at 2 AM when you really NEED a new liver.

  3. Re:News of the World by wonkey_monkey · · Score: 4, Funny

    Yes, the News of the World was renowned for its stories on 3D printing and cutting-edge medicine. Why, barely a day would go by without finding the words "native phenotypic behavior" on practically every page.

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    systemd is Roko's Basilisk.
  4. nearly there. by clickclickdrone · · Score: 3, Insightful

    Just need to print the bacon and you'll have a fine meal in no time.

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    I want a list of atrocities done in your name - Recoil
  5. Re:What about skin? by Lairdykinsmcgee · · Score: 3, Informative

    Great video. Not exactly what you're speaking about, but quite similar in effect. http://www.youtube.com/watch?v=eXO_ApjKPaI