Delayed Fatherhood May Be Linked To Certain Congenital and Mental Disorders

New submitter optimus_phil writes "New Scientist magazine reports on findings that suggest that delaying fatherhood may increase the risk of fathering children with disorders such as Apert syndrome, autism and schizophrenia. The article reports that 'although there is a big increase in risk for many disorders, it's a big increase in a very small risk. A 40-year-old is about 50 per cent more likely to father an autistic child than a 20-year-old is, for instance, but the overall risk is only about 1 per cent to start with.'"

Comments

"Just" 1% ?

[cellocgw]

Personally I view a significant cogitative or social defect that has a one-percent chance of ocurring to be unacceptably high. That's several kids in each class year in any medium-sized elementary school.

So, yes, I would consider an increase from 1% to 1.5% to be important. Granted, reducing the base probability would be far more useful than dealing with the age-related increase, but either way, these are large numbers compared with, say the usual "cancer risk increases by 5x" headlines which ignore the base risk being maybe 1E-6.