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Stanford Bioengineer Develops a 50-cent Paper Microscope

An anonymous reader writes "Scope: A Stanford bioengineer has developed an ultra-low-cost print-and-fold microscope and is now showing others how to make one themselves. The 50-cent lightweight, paper 'Foldscope' — which 'can be assembled in minutes, [and] includes no mechanical moving parts' — was designed to aid disease diagnosis in developing regions." The paper describing the design is on arXiv, and a video demoing the microscope is attached below.

15 of 83 comments (clear)

  1. Also a recent TED talk by canadiannomad · · Score: 4, Informative

    Also a recent TED talk on the topic

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    Hmm, the humour and sarcasm seem to have been be lost on you.
  2. Not entirely made out of paper, of course. by Rhymoid · · Score: 4, Informative
    FTA:

    The Foldscope design accommodates different optical configurations, including spherical ball lenses, spherical micro-lens doublets (such as a Wollaston doublet), and more complex assemblies of aspheric micro-lenses.

  3. Summary of Thread by The+Cat · · Score: 4, Funny

    1. It will never work.
    2. Big fuckin deal. Made one myself over breakfast last week.
    3. Biology is a worthless major.
    4. At least 68 replies starting with the word "Actually"
    5. This is proof there's no God.
    6. Shut up teabagger
    7. Fuck beta
    8. I'm competing to be the world's biggest talking penis
    9. Four PhDs? No wonder you're a dumbfuck
    10. Someone dropped a bulldozer on your car? The problem is you.

    1. Re:Summary of Thread by bob_super · · Score: 4, Funny

      11. Useless because I can't use it to do heart surgery or Si lithography
      12. Will be destroyed by a patent from Big Optics
      13. How many bitcoins?

    2. Re:Summary of Thread by drkim · · Score: 4, Funny

      17. Oblig. XKCD:
      http://xkcd.com/860/

  4. Re:Lenses too? by beelsebob · · Score: 4, Informative

    The one shown in the video uses pinhole projection.

  5. Re:How to get the lenses by pz · · Score: 5, Insightful

    If you read the article (I know, I know) you'll learn that he uses industrial grit, also known as glass beads, which are tiny bits of glass that are reasonably spherical and ridiculously cheap. The quoted lens cost in the article is $0.17, but unless I'm misunderstanding something, like how special the grit is that he's using, or what kind of secondary selection process is required to pick out beads that will make good lenses, that should be closer to 0.17 cents, not 0.17 dollars.

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    Put my fist through my alarm clock with its ding-dong death inside my ear. - The Blackjacks.
  6. http://www.foldscope.com/ by steveha · · Score: 4, Informative

    They have a website devoted to this:

    http://www.foldscope.com/

    And the news on the web site is that they will give away 10,000 of these to people who volunteer to test them. If you think you could do a good job of testing, maybe you should sign up.

    http://www.foldscope.com/#/10ksignup/

    To me, the most impressive part is that he claims they have very accurate focusing. I believe he said "micron" focusing. I'm not sure how that works, but the paper is cut to a very accurate shape (the video showed some sort of computer-controlled cutter, it might even have been a laser cutter). By moving a tab I guess the paper can be made to flex predictably to focus the lens?

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    lf(1): it's like ls(1) but sorts filenames by extension, tersely
  7. A tip of the hat to Leeuwenhoek. by dpbsmith · · Score: 4, Interesting

    This is EXTREMELY cool. But it seems to me they might have given a tip of the hat to Antony van Leeuwenhoek, who developed spherical glass microscope lenses in the late 1600s. Well, I see their paper does: "Although the use of high-curvature miniature lenses traces back to Antony van Leeuwenhoek's seminal discovery of microbial life forms (8), manufacturing micro-lenses in bulk was not possible until recently."

  8. Why not put them out in schools ? by slincolne · · Score: 4, Interesting
    The developing world chant always gets sympathy, but what about the potential benefit in schools ?

    I can remember in school the problem getting accessed (more students than microscopes) and with these schools could give them to students.

    Not only are they useful in class, but potentially they might get students interested in looking a the wider world!

    It would also potentially drive someone to mass market them - laser cut them in school and fix in the lense (or worst case outsource the manufacturing to China)

    1. Re:Why not put them out in schools ? by esten · · Score: 5, Informative

      but what about the potential benefit in schools ?

      The kids do love them. And can assemble them by themselves.

      I'm a Stanford PhD student and for an outreach organization Science Bus we actually worked with 2-5th graders locally to each build their own microscope to keep. The Foldscope works well and actually found the projection ability great in the classroom so that multiple students can see the same thing at once.

  9. Re:Thank you come again by Anonymous Coward · · Score: 3, Funny

    No, indians are from India, the country on the Asian continent, making them indians. Your lack of geographical knowledge pegs you as USian.

    FTFY.

  10. 50 cents, per use.... by danknight48 · · Score: 2

    “I wanted to make the best possible disease-detection instrument that we could almost distribute for free,”

    And without any doubt.
    Unless "3rd world" countries spend 50 cents to create a new one each time, those diseases will be distributed for free.

  11. Re:How to get the lenses by TeknoHog · · Score: 2

    If you read the article (I know, I know) you'll learn that he uses industrial grit

    I think the questions on every Slashdotter's mind now are:

    1. Are the grits hot?
    2. Can I pour them down my pants?
    3. Where is Natalie Portman when you need her?
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    Escher was the first MC and Giger invented the HR department.
  12. Image of it in use by Verdatum · · Score: 2

    I had to do far too much wandering about to find a simple image of the thing as it is to be used. Hope this helps someone: http://imgur.com/RzvY6nf