Researchers Develop DNA GPS Tool To Accurately Trace Geographical Ancestry
Zothecula (1870348) writes "An international team of scientists has developed a process that allows them to pinpoint a person's geographical origin going back 1,000 years. Known as the Geographic Population Structure (GPS) tool, the method is accurate enough to locate the village from which the subject's ancestors came, and has significant implications for personalized medical treatment."
So, what if you parents came from two different parts of the world? How does that help at all in personalized medical treatment?
This seems kind of useless.
Just to be clear, they only did this for two populations of people: Sardinia and polynesia, both of which have the nice property that they are isolated and thus would not mix very much with the rest of the human population.
A fool and his hard drive are soon parted.
"Known as the Geographic Population Structure (GPS) tool, the method is accurate enough to locate the village from which the subject's ancestors came"
Short answer: No it isn't.
Long answer: No it isn't.
That is an astoundingly facile thing to claim. I'm British, heritage Scottish, English, some Irish -- for whatever that means (practically fuck all, genetically, given that the Scots, English and Irish have been interbreeding for millennia, and please spare me the "But the English came across in 500AD!!!!!!" stuff because while there was definite interbreeding with people from Germany and Denmark back then for one thing the majority of the genes are pretty stable and for another they bred with everyone and everyone bred with each other, because that's what humans do. The idea that the "English" came along and committed genocide on a massive scale and that there is somehow some mystical intrinsic difference between "Celtic" peoples (who were never "Celtic" in the first place; the Atlantic Celts are also a myth; common language does not imply either common culture or common genetics) and "Saxon" peoples is a myth perpetrated by the ill educated and the politically motivated). Unless they've somehow got accurate DNA maps of every village not only in Europe but, given we're talking *1000 years* here, every village this side of Mongolia and quite a few beyond, too -- which they haven't, because they do not exist -- they can't make this claim. Unless they're banking on the sheer weight of ancestors meaning we can all be placed in every fucking village in the whole of Eurasia. 1000 years is roughly 300 generations, working on a crude dead reckoning of 30 odd years per generation. Pep quiz: what's 2^300? Answer: a first guess at the number of ancestors you had in 1014AD! That's a fucking big number. Obviously we have to cut it down to account for inbreeding etc., but even 2^100 is a hell of a lot of people, and some of them will be from entertainingly distant places.
The conclusion is either these people are selling snake oil (likely); the summary is bullshit misrepresenting what they actually said (near certainty); the answers they'll give are so general as to be meaningless (likely); or they'll actually perform some heavy filtering on their data so they can blithely say "your ancestors were from Denmark and we know that many were from the village of Aalsgard!!!!!!" and somehow keep a straight face (likely).
Proviso: I haven't read the article, because this is /.
How did they obtain a record of which genes were in which village at which time?
I have a DNA sequence from 23andme. I'd like to see the first service do any kind of analysis where I can upload my genome sequence and see the results of the analysis.
GPS is already taken by something else. This could cause some confusion.
If I can be modded down for being a troll, can I be modded up for being an orc, or a balrog?
Don't read the moronic gizmag article. (yeah I know, /., as if)
See this:
http://www.nature.com/ncomms/2...
It's pretty cool stuff.
Enough said.
Seastead this.
That's exactly what the politically correct retards behind this said! Even though the article summary clearly states " has significant implications for personalized medical treatment."
But wait a minute - they claim there's no such thing as 'race' - by which they really mean "White people aren't allowed to have their own countries, or they'll rise up against the Jews AGAIN and finally take their countries back for good, and be free of the yoke of Jewish tyranny, money lending, etc." and we can't have that...
Wow, this sounds like a really great idea. Except that 50 generations ago, there were theoretically 2^49 possible contributors to my DNA. Of course that number, 562,949,953,421,312, is far greater than the total number of humans who have ever lived, which implies that most of my ancestors must be "repeats". To put that another way, we are ALL inbred in the grand scheme of things. A familial relationship can be established between any given pair of living humans by going back less than 50 generations. That's right, Malcolm X and the Grand Wizard of the KKK are cousins. You knew that already -- it's not like there's anywhere else for humans to come from than other humans. The implication for this purported study, I think, is that it is nonsense. Pick any living human, and any 1000-year-old town. Yes, that person "came from" that town.
My mom emigrated from japan and my dad is from czech republic. How on earth could you trace my ancestors to a village? Going back 1000 years there are potentially several hundred villages to choose from.
PS: People with fair skin and red or blond hair have some genetic information from Neanderthal ancestors.
It is a pun on that thing, so no.
Bio questions? Ask me to start a Q&A journal. Computer analogies available for most topics!
But my ancestors were nomadic native Americans, you insensitive clods!
It's a technique with significant problems and that can and will give fairly meaningless results. Go back 1000 years and you don't have one ancestor you could have millions if not billions of ancestors, the vast majority from which you inherit nothing.
Not to mention the dodgy nature of authors declaring they have no financial interests in the paper then set up a company selling the results for a profit.
For proper look at the paper see the comments by one of the original reviewers:
http://jkplab.org/2014/04/30/review-geographic-population-structure-gps-of-worldwide-human-populations-infers-biogeographical-origin/
And a summary of some of the problems in this write up:
http://cruwys.blogspot.co.uk/2014/05/driving-in-wrong-direction-with-dodgy.html
Which Island? It might work on a small island like Mauke (in the Cooks) but it isn't going to work with The North Island.
Yes, I was going to say the same. Going 1000 years or so back, at a rate of 1 grandfather = 50 years, I have roughly a billion ancestors (some of whom will appear many, many times in different branches of my family tree, of course - but that's neither here nor there). I would be really, really impressed by a technique that could tell me where every one of them came from!
To be fair - watch the video, and that's not remotely what the researcher claims; it's much more balanced than that.
There isn't such a thing as "race". Humans are on a continuum of genetic traits. There are no clear boundaries that one could call "races". There are some genetic traits that are more prevalent in people from specified geographic regions, but a) not everyone in that region has the specified trait and b) other genetic traits have different geographic coverages.
PS: People with fair skin and red or blond hair have some genetic information from Neanderthal ancestors.
You are right; Some might call Centaurs a separate Race but other than having a some slightly more prevalent Equine genetic traits they are otherwise just as Human as the rest of us. Same idea goes for mice and all other animals that share most of the same DNA as those of us in the "Human Race".
Hint: even if your chosen phrase is the one that perfectly describes your invention, discovery or whatever, it's best to check that its initialism isn't already in popular use for something else.
(inventor of the individual biometric measurer)
Confucius say, "Find worm in apple - bad. Find half a worm - worse."
For the people that HAVE gotten results, all you get for the money is a point on a Google map. If you are a pure-bred ethnic whatever, that point means something. If you are the child of a parent from Fiji and an aborigonal Australian, the point on your map will be halfway between those locations: useless information. Considering that a lot of us are children of parents from quite different locations these days, the odds of you getting a point on your map that means anything are not high.
If they don't get back to me by this coming Tuesday (2 business days), I'm charging it back via PayPal.
What a bunch of crap.
Honestly, that's not what it does. Rather than tracing your actual ancestry, it's looking at the geographic distribution of the various genes in it. Thus, it can't tell you the names of your ancestors, but it can certainly tell you where they probably came from.
Clear, Dark Skies
There is no such thing as race in conjunction with humans, as this would imply selective breeding. The equality of people do not mean that we are all equal in genes. That would be quite confusing, if everybody would look the same. We are all different and equal in rights.
Actually it appears that the gene for red hair present in Neanderthals is different than the gene causing red hair in Cro Magnons and their descendents. Parallel evolution, apparently. There are other genes though, and they tend to be more prevalent in European populations than elsewhere. Denesovian genes are also present in European and Asian populations, and an influx from another 'unknown' hominid as well is found in several Asian populations. The book 'Children of the Ice Age' brings up some of that, although I think the red hair gene was in a Scientific American article a few months back.
"Think about how stupid the average person is. Now, realise that half of them are dumber than that." - George Carlin
Crap, then I left off the point I wanted to make: The only genetically "pure" human genome, without inclusions from other hominids, is African.
"Think about how stupid the average person is. Now, realise that half of them are dumber than that." - George Carlin
Assuming an average child-bearing age of 20, 1000 years back would span 50 generations. 50 generations of parentage is well over 1 billion people. How could anybody in the modern world's lineage possibly be traced back to one (or even 4) location?
---- I'll take you in a Hunt deathmatch any day.
But with humans, it isn't so, except some remote villages or tribes far away from other humans, which for one or several generations are related only to people within the same group. In any other group of people (of none-sibblings or directly related humans), you always find at least one who has ancestors no other person within that group has.
...We can tell in the United States already if someone is native to America, Asia, Europe, or Africa...
And what does this tell you (and us) about POTUS?
--
Intelligence is realizing that nobody knows what they're talking about. Wisdom is realizing that you don't, either.