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States Allowing Medical Marijuana Have Fewer Painkiller Deaths

An anonymous reader writes: Narcotic painkillers aren't one of the biggest killers in the U.S., but overdoses do claim over 15,000 lives per year and send hundreds of thousands to the emergency room. Because of this, it's interesting that a new study (abstract) has found states that allow the use of medical marijuana have seen a dramatic reduction in opioid overdose fatalities. "Previous studies hint at why marijuana use might help reduce reliance on opioid painkillers. Many drugs with abuse potential such as nicotine and opiates, as well as marijuana, pump up the brain's dopamine levels, which can induce feelings of euphoria. The biological reasons that people might use marijuana instead of opioids aren't exactly clear, because marijuana doesn't replace the pain relief of opiates. However, it does seem to distract from the pain by making it less bothersome." This research comes at a time when the country is furiously debating the costs and benefits of marijuana use, and opponents of the idea are paying researchers to paint it in an unfavorable light.

13 of 217 comments (clear)

  1. Congressional Pharmaceutical Complex by Anonymous Coward · · Score: 5, Insightful

    You mean the War on Drugs was a complete waste of time and money and ruined millions of peoples' lives for no reason, while funneling billions of dollars a year to ruthless criminal warlords in South America?

    1. Re:Congressional Pharmaceutical Complex by flyingsquid · · Score: 4, Insightful
      The War on Drugs has been a failure- it's put millions of people in prison, cost our society billions of dollars, and fueled honest-to-God warfare in South America and Mexico- and Americans are slowly starting to realize this. That being said, I think we're running the risk of having things swing too far in the other direction. There seems to be this attitude out there that pot is harmless, and that's just not the case in my experience. In moderation, it's probably safe. But chronic use- long term use at high doses- seems to really fuck people up. I know people from high school who used to smoke once in a while, and they're fine- productive members of society, good spouses, good parents, etc. I also know people who went on to smoke weed daily for many years... and they're just not all there anymore. They're always in a pretty good mood, but it seems disconnected from what's going around. They're hard to connect to, they can't seem to empathize with other human beings, they seem scattered and their thought processes tend to run wild; there's a lot of creativity but they lack the focus to do anything with it. The PSAs were right: drugs DO fry your brain.

      I think alcohol and Prohibition are a good parallel here. Prohibition was clearly a disaster, and when used in moderation, alcohol is harmless and probably even beneficial. But long-term, daily use of alcohol in high volumes can really screw you up. All things in moderation. Just because you can't OD on pot doesn't mean it's safe to take as much as you want as long as you want.

    2. Re:Congressional Pharmaceutical Complex by The+Good+Reverend · · Score: 4, Informative

      Given legalization is extremely new, the conclusion of the article and study is grossly premature. Making matters worse in my opinion, is that the study only looks at a single element of drugs, and not the complete impact.

      California legalized marijuana 18 years ago, in 1996. http://en.wikipedia.org/wiki/C...

    3. Re:Congressional Pharmaceutical Complex by LoRdTAW · · Score: 5, Insightful

      " There seems to be this attitude out there that pot is harmless, and that's just not the case in my experience. In moderation, it's probably safe. But chronic use- long term use at high doses- seems to really fuck people up."

      Replace pot with Alcohol, cigarettes, HFC's, video games, etc. and its pretty much the same thing. How far can it swing in the other direction? You mentioned alcohol has bad long term effects. But despite this people still drink themselves to death, drive drunk and kill others or get killed, or become a raging ass holes causing mayhem. People still smoke cigarettes despite the exorbitant cost and adverse health effects including cancer. People still drink gallons of soda and sugar crap until their pancreas packs it in and shuts down. People play video games until they loose their jobs, wives, kids and home or in some cases, until they drop dead. There is nothing the government can do at that point other than prohibit it these things and we all know how that works out. It's either all with some restrictions (don't drive and you must be 18 years old).

      The people have to be the ones to use judgement. If someone smokes so much weed and they fry their brains then that is their fault. Just like the old 65yo blue collar retiree who spends every night at the bar downing 6+ pints until his liver fails (know a guy who this just happened to. sad). People have to be educated and they have to be smart.

      Oh and I can counter your burn out pot head story with an anecdote of my own: I have a friend who at one point worked two jobs and got a degree at the same time. I asked him how he did it his answer was "Copious amounts of marijuana bro." He smokes in the morning, on his way to work while at work and at home. He is very energetic, driven and lively. Quite the opposite of your theory. So it of course depends on the person.

      I have also known people who smoked a lot and were fucked up because they were fucked up to begin with. You just always assumed they were messed up because of the pot but meanwhile you never really knew them well enough and they were messed up in the head to begin with. I worked with a kid who would go berserk is he didn't smoke and he smoked all the time. If he drank he was VIOLENT. A night out with him meant he was going to get into a fight and usually win because he was a hulk of a man. Turns out his father was exposed to chemical warfare agents while in nam and had a lot of mental issues including PTSD. His father ambushed him and his mother with a knife thinking they were Vietcong which promptly ended that marriage. He also had a very dysfunctional life and had a lot of really fucked up friends (I mean what friend tells you to fuck their own mother because she thinks your cute and lets you actually follow through? Yea, those were his friends. They gave me the heebie jeebies). The smoking was probably medicating him.

      In the end legalizing it will create new problems but they will be far more petty than what we have today. We can rid ourselves of a large amount of violent crime, people in jail and money spent on ruining lives while fattening the wallets of war machine peddlers. I'd rather live in a world full of cheery burnouts than drug gangs chopping peoples heads off with box cutters and chain saws, prisons bursting at the seams with inmates who just become more angry and make plenty of angry new friends they can do business with once they get out and government paramilitary goons wielding surplus military hardware shooting first and asking questions later (oops! no drugs here. Sorry for shooting your dog and father, kids. Have a nice life!). Legalize it, please.

    4. Re:Congressional Pharmaceutical Complex by drinkypoo · · Score: 4, Interesting

      The War on Drugs has been a failure- it's put millions of people in prison, cost our society billions of dollars, and fueled honest-to-God warfare in South America and Mexico-

      The War on Drugs has been a complete success. It's put millions of people in prison (At significant profit to certain sectores), funneled millions of dollars to contractors at a cost to society of billions of dollars (to say nothing of the lost lives) and fueled honest-to-God warfare in South and Central America, ensuring a steady supply of cheap labor and a fairly effective barrier which deters most Norteamericanos from migrating South to more friendly environments like Panama or Costa Rica by car, van, bus, or box truck.

      I think alcohol and Prohibition are a good parallel here.

      Sigh. If you really understood the situation as well as you think you do, you'd know that the people behind the "War on Drugs" were completely aware of the results of prohibition; it doesn't matter if it's of alcohol or marijuana. They knew that it increased demand and literally created a profitable criminal class.

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
    5. Re: Congressional Pharmaceutical Complex by macs4all · · Score: 4, Insightful

      "After alcohol, THC (delta-9-tetrahydrocannabinol), the active ingredient in marijuana, is the substance most commonly found in the blood of impaired drivers, fatally injured drivers, and motor vehicle crash victims. Studies in several localities have found that approximately 4 to 14 percent of drivers who sustained injury or died in traffic accidents tested positive for THC."

      I call Shennanigans.

      1. Tests for THC Metabolites (which are ALL that the drug tests measure (rather than the incorrectly-stated delta-9 THC), have ZERO ability to determine whether a person was "high" at the time of the accident). That is because those Metabolites (but NOT the effects of the drug) stay in a typical human's bloodstream for weeks after the last "dose"; so, a statement regarding their presence in traffic accident "participants" has as much to do with establishing a causal relationship as mentioning their shoe size as a contributing factor.

      2. The anti-marijuana bias of that "study", and that of the person who propounds it, is transparently p, and laughably, evident by including "motor vehicle crash victims" (other than drivers). So what now? We have a new classification of negligence called "RIDING while high"??? Yeah, those people SURELY should be included in a study if impaired DRIVING...

  2. Up is down and hot is cold... by Anonymous Coward · · Score: 5, Insightful

    At least that seems to be US drug policy
    A common painkiller will kill you and a schedule 1 dangerous drug has medical benefits and cannot kill you regardless of dosage

    As far as the legal painkiller goes, Acetaminophen can destroy your liver and most NSAIDs increase your risk of stroke

    Opioids are the biggest culprit tho, what with their tendency to suppress breathing and cause death with relatively small doses. Add in the tendency to cause physical addiction and long term illegal use of stolen pharmaceuticals or heroin

    Are we living in crazy town, or is the will of the people finally being heard?

  3. ruthless criminal by whathappenedtomonday · · Score: 5, Informative

    warlords in South America? Don't forget the pharmaceutical industry, and all those other industries that benefit from prohibiting a natural competitor that needs little cultivation because it basically grows like ... well, weed.

    --
    I hope I didn't brain my damage.
  4. I disagree by msobkow · · Score: 5, Insightful

    ...marijuana doesn't replace the pain relief of opiates.

    No, for many people it's more effective than opiates. I know literally dozens of medical cannabis users who have given up opiate pain killers completely and replaced them with medical cannabis. But it's important to experiment with different strains and find what works for you; all cannabis is not created equal.

    Personally, I use Kush and Afghanistan strains and crosses for migraines. Over the years I've tried literally hundreds of strains, and looked into their breeding history, and came to the conclusion that it was Kush and Afghanistan strains that are the most effective for my migraines.

    Where an opiate pain killer will dull the pain of a migraine, the proper strain will completely eliminate all migraine symptoms for me within 5-10 minutes of consuming a half gram dose. Triptans, on the other hand, only work half the time and take half an hour to have any effect, if any. Opiates only dull pain and actually make the nausea of a migraine worse because they upset my stomach. Add in the addictive nature of opiates, and I think you can understand why I'd much rather use medical cannabis than prescription opiates for what ails me.

    --
    I do not fail; I succeed at finding out what does not work.
  5. Incorrect headline, summary by wmansir · · Score: 4, Informative

    This study has been misreported nearly everywhere. The study didn't find states with legalized medical marijuana had fewer deaths than non-legal states. Legalized states continually had more deaths per capita, and both groups had dramatic increased in opiate OD deaths over the period covered by the study. The researchers found OD death rates in legalized states increased ~25% less than expected.

    I don't have access to the full study, but this chart included in this Washington Post article shows both groups OD death rate increase dramatically over time. It's interesting to note the change from 2009-2010, which significantly narrowed the gap between the groups. Prior to that year both groups seemed to be on similar trend lines. That said, groups moved from the illegal to legalized group over the course of the study and I'm not sure if or how the chart was adjusted for those changes.

  6. Re:Painkillers, HA! by apraetor · · Score: 4, Informative

    Opiates and opioids work on several subtypes of opioid receptors, which are present in locations besides the brain. The mu-opioid receptions in the brain are responsible for the sense of euphoria the drugs produce, but those receptors, along with kappa- and delta- variants, modulate nociception (pain sense). If opioids didn't actually work directly on pain then intrathecal morphine wouldn't work as well as it does.

  7. No by kipling · · Score: 4, Informative

    I don't think so. The JAMA article http://archinte.jamanetwork.co... does look at longitudinal effects but the 25% figure comes from comparing states with and without. From the abstract:
    States with medical cannabis laws had a 24.8% lower mean annual opioid overdose mortality rate (95% CI, 37.5% to 9.5%; P=.003) compared with states without medical cannabis laws.
    The common way to statistically analyse the effect of one variable is to model as many variables as the data allows and run a regression to isolate the effect of the target variable.
    It may be that there are other problems with the study (e.g. correlations between the variables assumed to be independent) but this isn't one of them.

    --
    -- open source? sounds like the real book --
  8. Re:Wouldn't edibles have the same effect by sound+vision · · Score: 4, Interesting

    I'm in the US and have been a daily potsmoker for the last 8 years (barring a few months break). I have never seen tobacco mixed into a joint, not once... it seems to be a European thing. Now, there is the practice of using cigar wraps to roll a "blunt", and sometimes those cigar wraps are made from tobacco pulp, so that could be seen as mixing tobacco with marijuana. I prefer not to smoke blunts, either.

    Scraping the crystals (technically trichromes) off cannabis is how hashish is made. Dissolving it into a solvent, then evaporating the solvent, gives liquid hash oil (also called honey oil, dabs, wax). Dabs are becoming more prevalent within the past few years as they are theoretically healthier, having a better ratio of plant material to THC. A recent issue of High Times featured a method of extracting hash oil using drinking-grade ethanol, instead of butane which was the formerly used process. Not only is it less likely to explode, it also placates people who are arbitrarily afraid of "chemicals", so I see dabs gaining massive popularity within the next few years.