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Scientists Sequence Coffee Genome, Ponder Genetic Modification

nbauman sends word that researchers have completed a project to sequence the genome of Coffea canephora, a species of plant responsible for roughly 30% of the world's coffee production. In the course of their genetic mapping, the researchers "pinpointed genetic attributes that could help in the development of new coffee varieties better able to endure drought, disease and pests, with the added benefit of enhancing flavor and caffeine levels." They also discovered a broad range of genes that contribute to the production of flavor-related compounds and caffeine. Plant genomist Victor Albert said, "For any agricultural plant, having a genome is a prerequisite for any sort of high technology breeding or molecular modification. Without a genome, we couldn't do any real advanced research on coffee that would allow us to improve it — not in this day and age."

30 of 167 comments (clear)

  1. But by rossdee · · Score: 2

    I don't drink coffee

  2. Please Add THC by Anonymous Coward · · Score: 3, Funny

    Add THC to the coffee bean, sell it at Starbucks. You'll make billions.

    1. Re:Please Add THC by rmdingler · · Score: 4, Funny

      With regards to THC, I believe the acronym GMO mostly still means grow my own.

      --
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  3. Le sigh.... by wbr1 · · Score: 5, Interesting
    I am not some anti-GMO freak, although I think it is hubris to assume that we can tinker with genomes without unintended consequences. This quote:

    Without a genome, we couldn't do any real advanced research on coffee that would allow us to improve it — not in this day and age.

    Is pure shite. It is called selective breeding, and it has been done for centuries. While that may not be advanced enough for you tastes, it works, and it improves plant varietals. You do not have to splice DNA to make improvements.

    One day we may just go to far and drop like honeybees in a Monsanto cornfield.

    --
    Silence is a state of mime.
    1. Re:Le sigh.... by mod+prime · · Score: 2

      We've been tinkering with the genetic makeup of our crops for thousands of years, you called it selective breeding. It basically means growing lots of crops and waiting for the DNA to be mutated in ways that appear on the face of it to be really cool and aggressively breeding that strain. We don't know where the mutation happened, what pleitropic effects it might have, and whether it will cause us all to 'drop like honeybees'. Then we repeat the genetic crapshoot over and over again. The difference with GMO is that we're not doing it completely blind.

    2. Re:Le sigh.... by mellon · · Score: 2

      And yet, ironically, does not taste like chicken!

    3. Re:Le sigh.... by Charliemopps · · Score: 5, Interesting

      I am not some anti-GMO freak, although I think it is hubris to assume that we can tinker with genomes without unintended consequences. This quote:

      Without a genome, we couldn't do any real advanced research on coffee that would allow us to improve it — not in this day and age.

      Is pure shite. It is called selective breeding, and it has been done for centuries. While that may not be advanced enough for you tastes, it works, and it improves plant varietals. You do not have to splice DNA to make improvements.

      One day we may just go to far and drop like honeybees in a Monsanto cornfield.

      Don't you think selective breeding would be a tad easier if you knew what you were breeding for? Not all GMO is done by chemically modifying the genome. You can identify your target gene, select seeds that contain the desired genes, pollinate them with plants that contain only those genes.

      I know there's a lot of movies that demonize this process, but in reality what they are doing is not any different than what happens in nature. It's just that instead of getting random mutations over and over until we get what we want, we just go strait to the goal. If anything it's probably safer. When doing it with selective breeding we get tens of thousands of undesired variants before we get the plant we want. How many of those could have been the plague bringer? When we chemically modify the gene, we're only rolling the dice a single time.

      And for the record, no man made GM food has ever harmed a bee. Quite to the contrary, many GM plants were designed to need less pesticides and fertilizers, which definitely do harm bees. The one downside of GM plants in regards to bees is that they allow farmers to plant large monocultures with less of a chance of disease killing those plants. Bees are healthier in more diverse environments, so it would be better if they diversified their crops rather than just plant what has the highest price this year.

    4. Re:Le sigh.... by jabuzz · · Score: 3, Interesting

      Clearly you have never heard of proteomics then. The idea that GMO is completely blind as to the possible effects is uneducated nonsense. Given that traditional selective breading requires no proteomic testing for unintended side effects, any sane rational person looking at the facts would conclude that GMO is in fact safer.

  4. Truly priority one. by nimbius · · Score: 4, Funny

    knowing the threat to our vital supply of hot black ichor was in peril, scientists of all fields have clearly exhibited a remarkable drive to solve this problem. Cancer, supercomputing, and most modern breakthrough technologies would have ground to a halt without some means of ensuring a steady supply of our dark glory bean. In honor of these brave scientists, I propose a toast of the finest coffee this mornings breakroom has to offer.

    --
    Good people go to bed earlier.
  5. News flash by invictusvoyd · · Score: 2

    A potent skunk variety of coffee has been recently banned !! . Reports suggest the so called "lunar launcher" could be 20-40% more potent than regular coffee. Some states are pushing for a legislation to allow it for medical use.
    _________________
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  6. Re:More caffeine? Better flavor? Higher crop yield by NoNonAlphaCharsHere · · Score: 5, Funny

    Coming soon to a Monsantobucks near you!

  7. Nothing is ever good enough by LookIntoTheFuture · · Score: 2

    Don't fuck with my coffee!!!

    --
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  8. This is robusta coffee they're talking about by Zontar_Thing_From_Ve · · Score: 5, Interesting

    I was not familiar with the name coffea canephora so I looked it up. This is what I have heard in the past called coffea robusta. Maybe the name got changed to disguise what it is. A lot of people know what robusta coffee is. For those who don't know, robusta is considered an inferior species of coffee. Ever heard of coffees that say that they are 100% arabica? This is because just about everybody considers arabica to be superior to robusta. Robusta is used in blends because it is is very bitter. Robusta is more disease resistant and has higher crop yields than arabica, but I've never heard of it being used in concentrations of more than maybe 1o to 15% in blends. Usually the amount used is less than 10%. This is great, I guess, and I suppose if there were 100% robusta blends some crazy people would love it. Currently in the USA there's a big interest in making craft beers as bitter as possible. Those kind of people, who are in the minority, would probably love large robusta blends. But until they sequence and maybe talk about doing things to protect arabica from disease, this is mildly interesting and no more.

    1. Re:This is robusta coffee they're talking about by Demonantis · · Score: 2

      Starbucks is a fairly dark roast arabica for the regular coffee. The Pike Place is a medium roast so ask for that if you don't like the default. Robusta is popular in Sweden(?), I think. They switched over to it in the early 1900s(?) and everyone just grew accustomed to the taste. Its all about different strokes for different folks.

    2. Re:This is robusta coffee they're talking about by omems · · Score: 2

      Good catch.
      They go on to, "present a draft genome of the diploid Coffea canephora, one of the two founder species of the tetraploid crop Coffea arabica." Which is to say, in the course of evolving, the genome was duplicated. Then, with a redundant set of genes, there was greater opportunity for mutations to either inactivate one copy, or have novel functions arise--like new flavonoids and alkaloids. Compared with most animal species, plants as a whole are particularly amenable to genome duplications, for reasons I don't know.

    3. Re:This is robusta coffee they're talking about by brianerst · · Score: 2

      So, then theoretically they could also sequence the arabica bean and figure out which alleles cause the "better flavor" of arabica and breed and/or modify versions of robusta that contain those flavor-positive alleles. Arabica flavor in a more robust(a) plant. (Robusta plants are more disease resistant - perhaps the tetraploid nature of arabica make them more vulnerable).

      I've got no dog in this hunt - I hate coffee. But figuring out how to get better flavored coffee from the higher producing, more robust plant seems like a good thing.

  9. Motherfuckers by gatkinso · · Score: 2

    Coffee is already perfect. Mess with it at your peril.

    --
    I am very small, utmostly microscopic.
    1. Re:Motherfuckers by PopeRatzo · · Score: 3, Interesting

      If you think coffee is bitter, try making it in a cold press. You can still warm it up if you like the idea of hot coffee, but you won't get a bit of bitterness. Plus it brings out all the caffeine so you'll feel like you've just taken a cocaine suppository, which are also kind of bitter, by the way, which is why you should not eat them.

      --
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    2. Re:Motherfuckers by mellon · · Score: 5, Interesting

      I recommend that you try cold brew with a medium roast of good-quality arabica beans. Not *$$: go to your local co-op and get some good shade-grown beans. I've had good success doing a 12-hour cold brew: you take about a cup and a half of course ground coffee and add it to two quarts of water (I use a two-quart mason jar) and put it in the fridge overnight. After it's sat twelve hours, filter it through paper into another container. This is kind of an annoying process, and there are devices that you can get to simplify it, but I would start off just using a regular filter so that you can try it.

      The coffee this produces is much mellower than the equivalent coffee brewed hot. If you want it hot, it's okay to heat it: the reason you don't re-heat hot coffee is that the transition from hot to cold causes chemical changes that wreck the flavor, but the transition from cold to hot doesn't have this effect.

  10. Glow in the dark coffee by sideslash · · Score: 3, Insightful

    Let's do it for science.

  11. The important thing by robstout · · Score: 2

    Isolate out the caffiene genes, and start adding it to other plants. There are times I'm eating breakfast, and I'm thinking "Why am I only getting caffiene from the coffee? Buzz up them hashbrowns! Perk up that toast! If we can introduce it into animals, think about caffinated eggs, or butter, or cheese. We can finally jitter up the world.

  12. Re: Coffea canephora = robusta = less important by Anonymous Coward · · Score: 2, Insightful

    I have a feeling that they will try. There is something troubling about all the world's good coffee being a genetic monoculture, especially given that Arabica is a rather sensitive plant. Robusta gets its name not for the kind of coffee it produces, but because it's just hardier and less fussy to grow. If I could help direct the research, I would say that they figure out what is responsible for the pleasing flavor of Arabica, and get Robusta to taste like that.

  13. Re:Yeah, because that's a good idea. by mellon · · Score: 2

    The problem with Monsanto modifying the genes of plants is that:

    • they make plants that produce chemicals to kill pests, with possibly unknown health effects (although at this point these effects have been studied pretty thoroughly)
    • they make plants that are resistant to herbicides, which promotes the use of these herbicides, which promotes the development of superweeds
    • they patent everything and engage in licensing schemes that are really harmful to small farmers.

    In my mind, the last item is the one that I care most about, although the superweeds are a close second. Also, as kruach aum says, you appear to be pretty ignorant about how this all works, so your opinion as to what's safe or unsafe or a good idea is not well-informed, and hence not something anybody needs to pay much attention to. I say this not to put you down, but rather to encourage you to become better informed: to actually try to understand the science rather than just making a simplistic mental model of it and then conjecturing on the basis of that model. That way of thinking is extremely damaging to our culture at present, and you really should stop doing it.

  14. Decaffeinated coffee by Anonymous Coward · · Score: 2, Insightful

    Genetic modification is probably the only way to make decaffeinated coffee that's still tasty. Breeding for low caffeine content produces sickly, unproductive strains, and decaffeination ruins the taste. There's a huge market for decaffeinated coffee that tastes less bad:

      http://www.economist.com/node/1858921

    It's a problem. Snobby espresso shops usually refuse to even make decaf. Also decaffeinated coffee isn't really caffeine-free, so this could be improved. It's about 0.1x as much caffeine as regular coffee:

      http://www.webmd.com/diet/news/20061011/decaf-coffee-isnt-caffeine-free

    Breeding methods probably won't do better than that, but proper genetic engineering might.

    I realize you personally may like as much caffeine as possible in your coffee, but that doesn't mean there isn't a huge untapped market for better decaf.

  15. Apoplectic by RogueWarrior65 · · Score: 2

    The coffee world is already deep in bed with the organic, fare-trade, square-deal, jump-through-hoops, still-tastes-the-same movement(s). GMO coffee will make these folks lose their excrement in old testament fashion. Should be amusing to watch.

  16. Re:Dont mess with my coffee!!!! by king+neckbeard · · Score: 2

    There's no logic behind your argument. Selective breeding is by definition not 'natural. Also, you might want to look up 'horizontal gene transfer.' Nature transplants genes too, and in a less controlled way. The technology is not inherently flawed, but there are issues with out usage, including biodiversity.

    If you want to ban patents on GMO, I am 100% with you. That will be a blow to Monsanto but not get in the way of things like golden rice.

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  17. Re:No more GMOs! by Anonymous Coward · · Score: 3, Funny

    spherical sheep vs cubical cow. FIGHT!

  18. Re:Dont mess with my coffee!!!! by omems · · Score: 3

    Assuming you're talking about the Vendômois study, that paper was retracted by the journal.

    The line of rats used are prone to tumors even with normal food. Combine that with a small sample size and one cannot say whether it was the food or their normal bad genes that caused the tumors.

    I'm not saying it's impossible, but to my knowledge there are no well-designed studies that actually demonstrate a causal link between eating GMO foods and disease.

  19. Re:Agreed by cellocgw · · Score: 2

    Um, evolution in most plants is "trying to make them taste BAD", otherwise, they... get eaten.

    You got any idea how / why there is yummy fruit surrounding a seed?

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  20. Re:Yeah, because that's a good idea. by kurzweilfreak · · Score: 2

    they make plants that produce chemicals to kill pests, with possibly unknown health effects (although at this point these effects have been studied pretty thoroughly)

    The effects and method of action of BT genes and their subsequent Cry proteins are well known, understood, and regularly used even in organic agriculture. All plants naturally produce their own chemicals/pesticides, otherwise pests would just be eating the shit out of them and they'd go extinct. Adding one more already naturally occurring pesticide that is demonstrably unharmful to humans is really no sweat.

    they make plants that are resistant to herbicides, which promotes the use of these herbicides, which promotes the development of superweeds

    Herbicides such as glyphosate were in use long before genetic technology came along, and for good reason: it's relatively benign compared to other more harsh and toxic herbicides that it replaced, and it was much more successful because it was broad spectrum and could kill a wide variety of pest plants rather than having to use two or three different herbicides to accomplish the same. It's for all these reasons that it was chosen as the target for resistance engineering, not the other way around. The idea of "superweeds" is a little ridiculous because at worst, weeds become resistant to glyphosate and we're simply right back where we started before. It's not like these weeds are suddenly going to be super hardy and resistant to everything and begin taking over the world. They'll simply be resistant to glyphosate.

    they patent everything and engage in licensing schemes that are really harmful to small farmers.

    When you're spending hundreds of thousands to millions on R&D, you kinda want to protect your investment. Plant patents have been around a lot longer than GMO technology anyway. Farmers are falling over each other trying to buy GMO seeds, and no one is forcing them to sign contracts that they don't want to. Anyone is free to go and buy non-GMO seeds wherever they like. Farmers aren't doing this, of course, because the GMO traits allow them to get better yields with fewer inputs, thus making better profits. GMO crops hurting small farmers is laughable to the farmers using them. Unless you think farmers are stupid hicks who don't know how to math.

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