Obama Administration Seeks $58M To Put (Partly) Toward Fighting Ebola

The Associated Press reports (here, as carried by the Washington Times) that The White House is asking Congress for $58 million above current levels to speed the production of promising drugs to fight Ebola and additional flexibility for the Department of Homeland Security to cope with the thousands of unaccompanied Central American children still arriving at the southern border. ... [T]he $58 million request for the Centers for Disease Control would help the agency ramp up production and testing of the experimental drug called ZMapp, which has shown promise in fighting the Ebola epidemic in western Africa. It would also help keep the development and manufacturing of two Ebola vaccines on track. The White House request also seeks to use $10 million in unused balances at the Department of Health and Human Services to help with the Ebola outbreak in Africa. The scarcity of ZMapp, the most promising treatment known for Ebola, is such that the third U.S. doctor to have been returned after being infected by the disease will be treated without it.

Comments

cost-benefit

[supernova87a]

When you compare against all the other assinine things that $58 M have been spent on (to the tune of being merely a drop of the bucket in larger spending bills) within pork programs, we should be jumping to take advantage of helping in this situation. The level of waste in this kind of spending is close to zero.

Re:Nice

[Artifakt]

Fast mutation does not equal fast evolution. RNA based viruses mutate a lot faster than DNA based organisms because single helix RNA has less error correction than DNA. Single celled organisns mutate more than multicelled organisms that can protect their reproductive cells inside their outher layers, cells with nuclei have lower mutation rates than un-nucleated cells, and there are several other changes in organisms that reduce the mutation rate further which I won't bother to go into. But that doesn't translate to the organisms evolving faster. Any organism that survives to reproduce is pretty close to being a perfect fit for its environment. That's why evolution isn't about big, sudden jumps, A big change positions an organism so that it is much farther from perfectly adapted, and only a small change has any chance of positioning the organism closer to perfectly adapted for its local conditions, without overshooting. Viruses are so simple that just about any change is a big change. If, just for the sake of argument, we say that only 1 in 100 mutations in an 'advanced' organism (i.e. flounder, oak trees or us) is an improvement, then only 1 in 100,000 or 1 in a Million or an even lower ratio of changes is similarly beneficial to a virus.
        Imagine a giraffe, that is within a couple of inches of being the perfect height to reach the highest branches it needs to eat from. Figure that if a single mutation made a difference of 12 feet to that giraffe's height, the mutants would all have tremendous problems with pumping blood up to their brains, and be very unsuccessful. but a girraffe may have 20 different genes that each affect height in a small way, so a mutation can occur that gets that giraffe's descendents those couple of inches that actually count as an improvement, without overshooting wildly. A virus, on the other hand, may have one short gene for making a simple repeating structure that tiles to make its whole outer shell, and any change makes a structure that won't tile at all. The virus can mutate a lot, but every single time it gets any possible mutation on that gene, it dies without reproducing at all. Huge amounts of mutation are possible ,where maybe 20% of each generation dies of that one mutation before final assembly, but no evolution happens at all.

I do like the idea of people choosing to donate for various projects, if they can be confident the government won't transfer the donations to other areas. I think even a system where people have to pay a given amount of taxes, but get to decide how much they want to go to what government projects would be an improvement.