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Schizophrenia Is Not a Single Disease

An anonymous reader writes: New research from Washington University has found that the condition known as schizophrenia is not just a single disease, but instead a collection of eight different disorders. For years, researchers struggled to understand the genetic basis of schizophrenia. This new method was able to isolate and identify the different conditions (each with its own symptoms) currently classified under the same heading (abstract, full text). "In some patients with hallucinations or delusions, for example, the researchers matched distinct genetic features to patients' symptoms, demonstrating that specific genetic variations interacted to create a 95 percent certainty of schizophrenia. In another group, they found that disorganized speech and behavior were specifically associated with a set of DNA variations that carried a 100 percent risk of schizophrenia." According to one of the study's authors, "By identifying groups of genetic variations and matching them to symptoms in individual patients, it soon may be possible to target treatments to specific pathways that cause problems."

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  1. Re:5 Ridiculous Myths You Probably Believe by mod+prime · · Score: 5, Interesting

    Well - they make you feel a little sluggish, and quite drowsy for about 8 hours (more at higher doses) after they kick in (so don't take them for breakfast if you have plans), but not depressed. It is possible to feel despair because of your chronic condition and the prospect of long term sluggishness I suppose but

    Schizophrenics who seek help often do so for anxiety and depression rather than psychosis. There is often a history of these issues predating medication, but not always.

    It's not just Hollywood, it's everywhere. The psychotic=violent myth is in every media that has discussed the issue. Newspapers only mention schizophrenia if someone was hurt, furthering the association in people's minds. My current employer refused to let me work without supervision because I had advised them I have had psychotic episodes and am undergoing treatment until I gave them a psych's letter telling them they were being morons (small and new business, so I forgave and educated instead).