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Researchers Report Largest DNA Origami To Date

MTorrice (2611475) writes Bioengineers can harness DNA's remarkable ability to self-assemble to build two- and three-dimensional nanostructures through DNA origami. Until now, researchers using this approach have been limited to building structures that are tens of square nanometers in size. Now a team reports the largest individual DNA origami structures to date, which reach sizes of hundreds of square nanometers. What's more, they have developed a less expensive way to synthesize the DNA strands needed, overcoming a tremendous obstacle to scaling up the technology.

15 of 36 comments (clear)

  1. Re:"Self-Assembling?" by rmdingler · · Score: 1
    No... what in the Universe could have assembled itself?

    Ah.

    --
    Happiness in intelligent people is the rarest thing I know.

    Ernest Hemingway

  2. Re: Eh, anyone here? by dreamchaser · · Score: 3, Interesting

    If you would bother to read before shooting off your mouth you'd see that there are plenty of potential applications. It's not just being done for the 'cool' factor.

  3. Re:Tens of square nanometers... by Anonymous Coward · · Score: 1

    Funny then how so many left wingers are so quick to spout ad hominem, vitriolic attacks. They must have small penises too! Maybe BOTH sides do! Perhaps it's time for a third party without all the hidebound rigid quasi-religious dogma and hatred!

  4. Re: Eh, anyone here? by dreamchaser · · Score: 2

    Technology doesn't just magically appear. It is worthwhile research that if it pans out could have some really wide ranging medical applications.

  5. Re:"Self-Assembling?" by Anonymous Coward · · Score: 2, Insightful

    If you're going to claim that 'DNA has been shown to be magnetoresponsive', you might consider offering links that have at least something to do with DNA. It might also help to not post utter crap about Earth's magnetosphere having a 'magnetic harmonic', let alone 'at the same frequency as the resonance demonstrated by DNA'.

  6. Re:"Self-Assembling?" by Anonymous Coward · · Score: 2, Insightful

    It doesn't self-assemble by magnetism, it self-assembles by hybridizing, Basically complementary bits of DNA pair up, and they like pairing up with complementary bits more then they like having the traditional double helix shape, so you can sort of weave with them.

  7. Re:Addendum by Anonymous Coward · · Score: 1

    No - much like your earlier claims, that work is utter idiocy. You might consider reviewing some criticism regarding it here:
    http://slashdot.org/story/11/01/13/0017256/nobel-prize-winner-says-dna-performs-quantum-teleportation

  8. Re:"Self-Assembling?" by Anonymous Coward · · Score: 2, Insightful

    Given that the Schumann resonances have peak amplitudes of a few picoteslas, it seems highly unlikely that they affect DNA assembly.

  9. Re:"Self-Assembling?" by K.+S.+Kyosuke · · Score: 2

    "Magnetic harmonic?" "DNA resonance frequency?" Nice try. You know, people here aren't stupid.

    --
    Ezekiel 23:20
  10. Re:"Self-Assembling?" by K.+S.+Kyosuke · · Score: 1

    1. There's no mention of either Earth's magnetic field or DNA in the Nature article, demonstrating that you can bullshit people twice for the price of one. Neat!

    2. The fact that Earth's magnetic field has a documented history of significant changes, reversals, and even almost-disappearances for time periods way beyond the lifetime of any single multicellular organism demonstrates at least that the function of DNA isn't significantly disrupted by absence or presence of weak magnetic fields.

    --
    Ezekiel 23:20
  11. Re:"Self-Assembling?" by Hex4def6 · · Score: 1

    I think any magnetic forces will pale in comparison to chemical forces at that scale.

  12. like a virus drill by doug141 · · Score: 2
  13. Re:Addendum by cinnamon+colbert · · Score: 1

    is this the same montagnier who claimed he could do immunology over the telephone ? (twisted pair, back in the day)'
    if you are a troll, congrats , you have gotten a lot of people riled up about your nonsense; if you are serious, politely, let me say that you are barking up the wrong tree here
    the nature article is about neuronal membranes, nothing to do with DNAassembly

    you might consider that people spend hours inside MRIs, where the magnetic field is ~~ 10,000 times that of the earth
    (oh, wait, now you have MRI magnetoresponsive DNA induced tumorigenisis....)

  14. Re:"Self-Assembling?" by cinnamon+colbert · · Score: 1

    uh, aren't these usually bp conserved, so they are iso energetic ?
    if the net number of bp is reduced, where is the deltaG to make this go ?

  15. Re:I work on DNA by RockDoctor · · Score: 1
    I see your points, but I'm also seeing a wet chemistry (if not exactly "bucket" chemistry) process that is producing what looks like pretty flat (nanometre level of flatness)surfaces in quite substantial areas. And the electrical properties of that substrate can be controlled to a significant degree. There's potential there for micro-mechanical systems, or chip substrates. Quite a lot of interesting potential there.

    Hypothesizing that you could use this to produce low-power electronics for, say a wireless environmental sensor of some sort, how does the idea of environmental sensors that are inherently biodegradable on a months-to-years time scale grab you?

    --
    Birds are not dinosaur descendants;birds are dinosaurs, for all useful meanings of "birds", "are" and "dinosaurs"