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Assembling a Micro-scale Biochemistry Lab Like Snapping LEGOs Together

An anonymous reader writes: Microfluidic systems promise to bring the same level of precision and control seen in the electronics industry to chemistry and the life sciences. Typically, devices are fabricated at substantial cost and using borrowed techniques from the semiconductor industry. Researchers at the USC Viterbi School of Engineering have invented a system of discrete microfluidic elements akin to those found in electronic board design. It was inspired by the ease with which LEGO bricks are assembled into a larger structure, and finally allows for the rapid prototyping of "Lab-on-Chip" devices. The original paper is published in the Proceedings of the National Academy of Science.

26 comments

  1. Re:Hey, NERDS! by rolfwind · · Score: 0

    Are they ipad/iphone friendly unlike this site, whose only progress the last 15 years seems to be continually breaking the default comment threshold controls?

  2. Don't care by viperidaenz · · Score: 1

    I'm waiting for Lego-On-Chip

    1. Re:Don't care by Anonymous Coward · · Score: 0

      I'm waiting for Lego-On-Chip

      Ahem... Minecraft.

  3. Could this be used to create chemical weapons? by Anonymous Coward · · Score: 0

    I foresee something like this being a boon to terrorists who would love to make chemical or biological weapons of mass destruction. I suppose it's just a matter of time.

    1. Re:Could this be used to create chemical weapons? by Anonymous Coward · · Score: 0

      Only because the powers that be have gotten you scared. _everything_ useful to people is also useful to terrorists. If we stopped doing things that the bad guys also do then we are pretty limited.

  4. Ah, fluidics by 50000BTU_barbecue · · Score: 1

    When I was a kid my parents had a collection of very old Britannica supplements from the 1960s. Some sort of yearly book for each year after the main books came out.

    Anyways, when I was a kid I was always impressed by the pictures and the descriptions. One of the articles was about fluidics, the pictures of plates of metal with holes, piled up and bolted together and doing logic operations with boiling liquids and what not.

    I'm just wool gathering, but it seems like the 1960s were unusually fertile in all fields and it's fun to see one of these "anything goes"-type technologies still being useful after so long.

    --
    Mostly random stuff.
    1. Re:Ah, fluidics by ShanghaiBill · · Score: 2

      One of the articles was about fluidics, the pictures of plates of metal with holes, piled up and bolted together and doing logic operations with boiling liquids and what not.

      That is not quite the same, since the goal was logic, rather than chemistry. Fluid/pneumatic logic was used in early embedded ICBM targeting and control systems, because it could withstand a thousand times as much radiation as an electronic circuit of that era.

  5. My unwashed Lego ... by Anonymous Coward · · Score: 0

    ... is already a long-running micro biochemistry experiment..

  6. Re:Hey, NERDS! by Fwipp · · Score: 0

    They're mobile-friendly in that they serve you the desktop site. So it's not mobile-optimized, but hey, at least you can still use it. :)

    That said, it feels like slashdot still. I don't have a compelling reason to use one or the other.

  7. Oh noes! Grammar Nazi's untie! by Anonymous Coward · · Score: 0

    In B4 the Legos doesn't have a plural. Last time I said Legos on this site I got flamed hard!

  8. Re:Hey, NERDS! by rmdingler · · Score: 1

    Ask yourselves but one question... do you see a single thread, such as this, over there, promoting both sides of the argument equally without censure? There is but one true great nerd site. I'm posting on it.

    --
    Happiness in intelligent people is the rarest thing I know.

    Ernest Hemingway

  9. As if by Anonymous Coward · · Score: 0

    As if Slashdot readers don't already have enough experience with "micro-fluidic structures" (nudge, nudge, wink, wink!).

  10. Re: Hey, NERDS! by Fwipp · · Score: 1

    I have no idea what you're trying to say.

  11. "FPGA" chemistry on a chip=Star trek replicator by sg_oneill · · Score: 1

    "Make this drug on a chip" is kind of awesome, but the next step is the "FPGA" equivilent where novel compounds can be downloaded to it and have it assemble them from base compounds up. What might be implausible industrially due to having too many steps becomes plausible on the very small scale. From here we have the ability to have standard chemical inputs generate any given chemical output and we're on the way to 3D printers that can print almost anything. Thinking futuristically here, but thats your first step to a genuine star trek replicator without having to resort to imaginary quantum woo

    --
    Excuse the Unicode crap in my posts. That's an apostrophe, and slashdot is busted.
  12. The grammar of Lego by GrahamCox · · Score: 1

    Lego is the building material as a whole, therefore it's already a collective noun. So there's no such thing as "a lego", it's "a lego brick", and by extension there's no such thing as Legos.

    1. Re:The grammar of Lego by Hognoxious · · Score: 1

      Plus it's not an acronym.

      --
      Confucius say, "Find worm in apple - bad. Find half a worm - worse."
    2. Re:The grammar of Lego by Anonymous Coward · · Score: 0

      It's a mass noun rather than a collective noun. We have two litres of water and two lego bricks, as opposed to two waters and two legos.

    3. Re: The grammar of Lego by Anonymous Coward · · Score: 0

      Ya it is, no idea what the O is though

    4. Re: The grammar of Lego by Anonymous Coward · · Score: 0

      No it is not, it is http://aboutus.lego.com/en-us/lego-group/the_lego_history "The name 'LEGO' is an abbreviation of the two Danish words "leg godt", meaning "play well". It’s our name and it’s our ideal."

      But keep being stupid.

  13. Only sheeps say legos. by Anonymous Coward · · Score: 1

    'nuff said.

  14. Combine with self flowing tubes? by Anonymous Coward · · Score: 0

    I ran into this cool video, could these two techniques be mixed somehow?
    http://www.youtube.com/watch?v=WiRbu6uk_9A

    I am not an engineer, so it's hard to tell what is happening here, but it looks/sounds like an electronic coating of some kind makes the fluid move without a pump.

  15. No it's not by Hognoxious · · Score: 1

    It's more like bolting meccanoes together.

    --
    Confucius say, "Find worm in apple - bad. Find half a worm - worse."
  16. I'm not sure how I feel about this... by jeffb+(2.718) · · Score: 1

    As a chemistry hobbyist, I always wanted one of those big organic-labware sets with pluggable components -- you could build a multi-stage vacuum still, controlled-atmosphere reactor and separator, whatever you wanted -- but true micro- or nano-scale chemistry never seemed as appealing.

    By analogy, I always thought playing with discrete components or small-scale logic chips was a lot more engaging than wiring up a microcontroller and loading it with canned or slightly-modified firmware.

    On the other hand, you can unquestionably get a lot more done with the canned-complex-parts approach. I'll be fascinated to see where this leads.

  17. Re:Hey, NERDS! by Anonymous Coward · · Score: 0

    I see soylent news spammed on slashdot constantly (OP is pure spam - you may just be a blind fanboy). What kind of sad losers are you people, just move and stfu already - we do not care that you found another site, there are thousands after all. Whining about slashdot quality while being one of the people dragging it down is kinda sad.