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How Did the 'Berlin Patient' Rid Himself of HIV?

sciencehabit writes: Researchers are closer to unraveling the mystery of how Timothy Ray Brown, the only human cured of HIV, defeated the virus, according to a new study. Although the work doesn't provide a definitive answer, it rules out one possible explanation. [R]esearchers point to three different factors that could independently or in combination have rid Brown’s body of HIV. The first is the process of conditioning, in which doctors destroyed Brown’s own immune system with chemotherapy and whole body irradiation to prepare him for his bone marrow transplant. His oncologist, Gero Hütter, who was then with the Free University of Berlin, also took an extra step that he thought might not only cure the leukemia but also help rid Brown’s body of HIV. He found a bone marrow donor who had a rare mutation in a gene that cripples a key receptor on white blood cells the virus uses to establish an infection. (For years, researchers referred to Brown as "the Berlin patient.") The third possibility is his new immune system attacked remnants of his old one that held HIV-infected cells, a process known as graft versus host disease.

9 of 107 comments (clear)

  1. Simple. He's Immortal by Anonymous Coward · · Score: 5, Funny

    He can't die, you fool, unless his head comes away from his neck.

    now that he's outed, expect a seven-foot lunatic with a sword to come after him.

    1. Re:Simple. He's Immortal by Dutchmaan · · Score: 1, Funny

      There can be only Juan!!!!

    2. Re:Simple. He's Immortal by pushing-robot · · Score: 1, Funny

      He was not the Juan.

      --
      How can I believe you when you tell me what I don't want to hear?
  2. Not a thorough analysis by pushing-robot · · Score: 5, Funny

    Does the subject possess any mysterious rings, amulets, or lamps?
    Does he make sacrifices to chthonic gods, and if so, which?
    Did he recently undertake a quest to bring together a collection of ancient magic gems?
    Is the hospital frequented by a wizard or a druid cult?

    I appreciate the work they did, but when they don't even consider the patient being swapped with his twin from an alternate dimension it's hard to call it rigorous.

    --
    How can I believe you when you tell me what I don't want to hear?
  3. I am no dr. but come on! by funkymonkjay · · Score: 1, Funny

    there are only 2 things here:
    1. radiation treatment
    2. bone marrow from an x-man

    my money is on #2.

  4. To any fundamentalists who may have stumbled in... by hyades1 · · Score: 2, Funny

    Looks like those curses from god just ain't what they used to be. :-)

    --
    I've calculated my velocity with such exquisite precision that I have no idea where I am.
  5. Re:Host versus graft disease by MillionthMonkey · · Score: 1, Funny

    I think the patient in Berlin now has a Wall to isolate himself from incorporated viral entrepreneurs.

  6. Re:To any fundamentalists who may have stumbled in by sinij · · Score: 3, Funny

    Please, try being a Pastafarian. I get cursed with a terminal disease at least once before my morning coffee. Considering our vengeful god, it is amazing any of us still alive.

    Partially due to above circumstances, on a long enough scale, Pastafarian mortality approaches 100%.

  7. Re:Missing in the Summary by mythosaz · · Score: 3, Funny

    I assume everyone I sleep with has HIV.

    That's why I don't have to tell them about mine.