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Researchers Direct Growth of Neurons With Silicon Nitride Microtubes

MTorrice writes: Bioengineers want to connect electronics and neurons to make devices such as new cochlear implants or prosthetic limbs with a seemingly natural sense of touch. They also could build synthetic neural circuitry to use to study how the brain processes information or what goes wrong in neurodegenerative diseases.

As a step toward these applications, a team of researchers has developed a way to direct the growth of axons, the connection-forming arms of neurons. They use transparent silicon nitride microtubes on glass slides to encourage the cells' axons to grow in specific directions. The cultured nerve cells grow aimlessly until they bump into one of the tubes. The axon then enters the tube, and its growth is accelerated 20-fold. Silicon nitride already is used in some orthopedic devices, and could serve as a substrate for electronics to interface with the growing neurons.

1 of 23 comments (clear)

  1. Re:Well, it's a well known fact, by Mr+D+from+63 · · Score: 3, Interesting
    Not discussed in the summary, but possibly one of the most beneficial potential uses states in the source;

    The UW Medical Center’s Shain sees a potential therapeutic application for the tubes: helping axons grow across long distances to repair injuries. In the body, neurons typically won’t grow past a scar. With further development, these microtubes could be used to rebuild severed nerve bundles, he says.

    BTW, cool video in the source.