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New Virus Means Deadlier Flu Season Is Possible

HughPickens.com writes Donald McNeil writes in the NYT that this year's flu season may be deadlier than usual because this year's flu vaccine is a relatively poor match to a new virus that is now circulating. "Flu is unpredictable, but what we've seen thus far is concerning," says Dr. Thomas R. Frieden. According to the CDC, five U.S. children have died from flu-related complications so far this season. Four of them were infected with influenza A viruses, including three cases of H3N2 infections. The new H3 subtype first appeared overseas in March but because it was not found in many samples in the United States until September, it is now too late to change the vaccine. Because of the increased danger from the H3 strain — and because B influenza strains can also cause serious illness — the CDC recommends that patients with asthma, diabetes or lung or heart problems see a doctor at the first sign of a possible flu, and that doctors quickly prescribe antivirals like Tamiflu or Relenza. "H3N2 viruses tend to be associated with more severe seasons," says Frieden. "The rate of hospitalization and death can be twice as high or more in flu seasons when H3 doesn't predominate."

12 of 163 comments (clear)

  1. Re:Meh. by gatkinso · · Score: 3, Informative

    While not nearly as dramatic, my understanding is that flu kills many more people than Ebola does.

    But death rate aside - who wants to be laid up in bed for a week with fever and body aches?

    --
    I am very small, utmostly microscopic.
  2. Re:Meh. by CrimsonAvenger · · Score: 3, Informative

    making it much more important to politicians than tens of thousands of Africans!

    It must be noted that "tens of thousands of Africans" haven't died from ebola. Thousands, yes. Tens of thousands, no.

    --

    "I do not agree with what you say, but I will defend to the death your right to say it"
  3. Re:Meh. by Anonymous Coward · · Score: 2, Informative

    Flu will kill more Americans this year than Ebola will this decade.

  4. Re:Meh. by ranton · · Score: 3, Informative

    Flu will kill more Americans this year than Ebola will this decade.

    I think its safe to say the flu will kill more Americans this year than Ebola will this century, or more likely this millennium.

    --
    -- All that is necessary for the triumph of evil is that good men do nothing. -- Edmund Burke
  5. Re:Boy who cried wolf by bunratty · · Score: 3, Informative

    Where do you get this "end of the world" thing? As for the claim of "alarmism", do you not remember the flu strain several years ago that tended to kill healthy people in the prime of their life, rather than "immunocompromised hosts"?

    It's not that the reports are "alarmist". It's (1) you're not understanding the actual risk, and (2) you're pretending that the reports are predicting the end of the world.

    --
    What a fool believes, he sees, no wise man has the power to reason away.
  6. Boy who cried wolf by Anonymous Coward · · Score: 5, Informative

    Well I love your great anecdotal evidence, you should probably publish it and see how it goes. So, as an actual virologist and epidemiologist, let me try to explain here. First, please understand the difference between correlation and causation. Second, you may truly have a strong immune system helping protect you against seasonal flu or you may simply have very selective memory. Third, a strong immune system has actually been shown to be a detriment as it leads to what some scientists term a cytokine/chemokine storm (yes this specific terminology/pathology still debated) so enjoy that avoidance of a simple, cheap, and safe vaccine if we ever have to deal with such a strain. Fourth, the flu SHOT does not cause the flu, it is killed and will not lead to any type of viral infection directly from the shot. It is, of course, possible for the vaccine to be targeting the wrong strains as the article states the current one may but sorry to say it still is a partial guessing game and they will sometimes guess wrong. This is why good hygiene and health practices are also critical, not just the vaccine. Fifth, someone really has no understanding of herd immunity. One of the most critical aspects of the flu vaccine is it can protect the elderly, young, and immune compromised who themselves can't receive the vaccine or receive no direct benefit. Are you so cold as to avoid a simple and safe shot which could save your own child, or your parents/grand parents? What if your neighbors baby gets dies and we could trace it directly back to you (fairly easy to do through sequencing analysis)? Again, the vaccine is easy and cheap. The economic costs directly related to seasonal flu pay for it by itself, not including the life saving factors. It is simply ignorance, avoidance, and stupidity which can lead to such illogical jumps of "I never get sick so I don't need a vaccine" or "I only get sick when I get vaccinated". If you showed me a daily health report from the last 5 years where you reported your temp and clinical signs twice a day, I may believe you. Otherwise sorry to say I am sticking with selective memory.

  7. Re:Boy who cried wolf by thegarbz · · Score: 5, Informative

    I started paying attention to this crap in the late 90s when I realized 'it seems like every year we're going to have a horrible flu outbreak'

    Then you haven't really being paying much attention. Sure there's usually one or two attention grabbing whores on Fox News, but for the most part the only really alarmist case that was reported was H1N1, and rightfully so as it turned out. Maybe you should actually review how much airtime the CDC dedicated to the flu each year before you claim they are crying wolf.

    And while we're on the subject of the flu ... why is it that I'm the only one in my family that doesn't get a flu shot and I'm also the only one who has managed to not get the flu every year except for the year before last ... when doctors convinced me to get the flu shot because I had a newborn son ... ironic that I GOT THE FLU THAT YEAR.

    Not understanding how the vaccine works is not irony. Your survived a mild strain of the flu, congratulations. In the meantime, I, a healthy 25 year old who plays sports, eats a healthy diet, and hadn't had so much as a sneeze in the years preceding managed to get hospitalised for 2 weeks when I caught the flu. It took most of the year to get back into the shape I was before I caught it, but it's good to know that you think everything is ok and we should all just brush it off. By the way did they tell you which stain of flu you got? There's only about 100 of them, I assume you got a vaccine for each one? No?

    I'm also interested in how your entire family manages to get the flue every year when only about 0.04% of the population is diagnosed with a strain of influenza in the USA in any given year.

    The flu is scary for immunocompromised hosts, which is basically no one other than HIV/AIDS carriers and older people. Even freaking kids have an immune system that does well against it.

    Wow. I didn't realise one could have so much ignorance in one statement but still get out the word immunocompromised. Certainly it's only the million or so AIDS suffers that died in the last flu pandemic right? Right? Wrong. Of note as well is that the H1N1 outbreak in Australia killed people with a median age of 53. Healthy adults fell victim to it. The Hong Kong Flu killed a shitload of people.

    I'll leave you with a lovely little saying:
    "About 10 times a year a person will catch a cold and think they have the flu. About once in every 10 years a person will catch the flu and never again confuse it with a cold."

  8. Re:Meh. by Anonymous Coward · · Score: 4, Informative

    Never heard of herd immunity? Your minor inconvenience could save an immunocompromised person.

  9. Re:Meh. by Anonymous Coward · · Score: 2, Informative

    Everyone who gets the vaccine is guaranteed to feel crappy and be less productive that day

    No. You're wrong, and you're spreading misinformation.

    First, from the flu shot? Your arm might be sore that day, and that's generally about it. The odds of getting even a low-grade fever or being achy are quite low.

    The flu mist, on the other hand, uses weakened but live virus, and causes lots of side effects. They're generally mild, of course, but the mist is the one they often give to children, who you've already admitted probably need it.

    Plus, getting vaccinated isn't just for you, it also helps stop the spread of disease.

  10. Re:Meh. by dywolf · · Score: 4, Informative

    because the flu kills many more people than ebola, and is actually worth worrying abuot?
    because, unlike ebola, the flu doesnt burn itself out.
    ebola kills too easily and spreads with difficulty, which limits its spread and capabilty to harm large numbers.
    the flu, being more contagious and less deadly on an individual basis, is able to infect more people and thus kill more people.

    ebola is still below 10k fatailities for this outbreak.
    the flu ranges between 3k and 49k every year, averaging >20k.

    flu also causes a bigger drain on the world's economies, with lost production, costs spent on treatment, workers staying home, etc, than most other "scary" diseases.

    and this is "average" considerations, where the article is about how this years flu season may be exceptional due to the vaccine being less capable than expected compared to the expected viral strain.

    --
    The guy who said the election was rigged won the presidency with the second-most votes.
  11. Re:Boy who cried wolf by minstrelmike · · Score: 3, Informative

    It's not that the reports are "alarmist". It's (1) you're not understanding the actual risk, and (2) you're pretending that the reports are predicting the end of the world.

    Yup. that applies to most of the comments.
    Viruses mutate and flus occur regularly. Occasionally, one is deadly.
    To get in front of evolution and have 50 million vaccines ready for distribution, you need to make educated guesses.
    This year we guessed wrong. That's the gist of the article.

  12. Re:Looks like the mismatch nailed me by jratcliffe · · Score: 2, Informative

    The Flu vaccine is no more effective than random chance, but it's a huge money maker for the pharmaceutical industry.

    Got any actual evidence for this claim? I see your unsupported assertion, and raise you a page of peer-reviewed studies.

    http://www.cdc.gov/flu/about/q...