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Scientists Say the Future Looks Bleak For Our Bones

HughPickens.com writes Nicholas St. Fluer reports at The Atlantic that according to researchers, our convenient, sedentary way of life is making our bones weak foretelling a future with increasing fractures, breaks, and osteoporosis. For thousands of years, hunter-gatherers trekked on strenuous ventures for food with dense skeletons supporting their movements and a new study pinpoints the origin of weaker bones at the beginning of the Holocene epoch roughly 12,000 years ago, when humans began adopting agriculture. "Modern human skeletons have shifted quite recently towards lighter—more fragile, if you like—bodies. It started when we adopted agriculture. Our diets changed. Our levels of activity changed," says Habiba Chirchir. A second study attributes joint bone weakness to different levels of physical activity in ancient human societies, also related to hunting versus farming.

The team scanned circular cross-sections of seven bones in the upper and lower limb joints in chimpanzees, Bornean orangutans and baboons. They also scanned the same bones in modern and early modern humans as well as Neanderthals, Paranthropus robustus, Australopithecus africanus and other Australopithecines. They then measured the amount of white bone in the scans against the total area to find the trabecular bone density. Crunching the numbers confirmed their visual suspicions. Modern humans had 50 to 75 percent less dense trabecular bone than chimpanzees, and some hominins had bones that were twice as dense compared to those in modern humans. Both studies have implications for modern human health and the importance of physical activity to bone strength. "The lightly-built skeleton of modern humans has a direct and important impact on bone strength and stiffness," says Tim Ryan. That's because lightness can translate to weakness—more broken bones and a higher incidence of osteoporosis and age-related bone loss. The researchers warn that with the deskbound lives that many people lead today, our bones may have become even more brittle than ever before. "We are not challenging our bones with enough loading," says Colin Shaw, "predisposing us to have weaker bones so that, as we age, situations arise where bones are breaking when, previously, they would not have."

6 of 115 comments (clear)

  1. Evolutionary tradeoffs... by Anonymous Coward · · Score: 4, Interesting

    ... what we get in weaker bones, we get in more refined minds (aka sitting and reading, researching, etc). Now some may laugh at this idea in the modern era, but you have to remember you only have so much time and energy as an organism. It'd be interesting to know whether bones needing lower maintenance/energy has some pro's instead of just cons.

  2. Density vs fractures by manu0601 · · Score: 3, Interesting

    It is amazing how researchers are able to ignore results from other fields. We know that bone density is not a good predictor for fractures. On the other hand, we know that dairy product consumption is correlated with higher density and fractures.

    There is no consensus on how to explain that, but one interesting theory is that dairy products promote bone metabolism (hence the higher density) up to renewal exhaustion (hence the fractures).

    1. Re:Density vs fractures by Anonymous Coward · · Score: 2, Interesting

      What fields claim that bone density doesn't predict risk of fractures? There's a reason we do bone densitometry studies for people at risk of osteoporosis. Obviously they won't tell an individual whether or not they're going to have a bone break in the next 6 months, but for a population they're great for picking out who needs to pay more attention to their step and gait, and who could benefit from a bit of a bisphosphonate to sturdy up dem bones.

      Read any reputable meta-analysis since the 80's and you'll find evidence supporting this. I found a few studies correlating fractures with decreased trabecular bone as well, especially with spinal compression fx's. About the only controversy you'll find on this point is on which groups should have densitometry performed.

      Anyway, looking at the study results, if our trabecular bone really is weak and pasty compared to our ancestors', then yea, we're probably likely to suffer more breaks. Lots of possible confounders, as others have pointed out.

      Some references, though I'm not at work so I can't access the premium shit.
      http://www.ncbi.nlm.nih.gov/pubmed/8634613
      http://link.springer.com/article/10.1007/BF02554913
      http://www.cof.org.cn/pdf/2009/1/International%20Society%20for%20Clinical%20Densitometry%202007%20Adult.PDF (potentially biased guideline article)

  3. Re: just do strength training by bill_mcgonigle · · Score: 4, Interesting

    Classic nerds vs. geeks. Nerds are happy to be sacks of goo because exercise is not interesting to them. For geeks, everything is an optimization problem - the meatsuit gets no pass.

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  4. Re: Lazy farmer by MemeRot · · Score: 4, Interesting

    "pinpoints the origin of weaker bones at the beginning of the Holocene epoch roughly 12,000 years ago, when humans began adopting agriculture". This doesn't have anything to do with tractor farming.

  5. Re: Lazy farmer by Rei · · Score: 4, Interesting

    But it does raise a serious issue - they're studying changes that don't necessarily reflect the selective pressures of present-day life.

    Think about it: what are the leading causes of death for people in the prime breeding age (15-34)? Car accidents - by a good margin. So isn't this significant selective pressure to beef up the neck against whiplash, the skull against forehead impact, survival during significant blood loss, etc?

    #2 is suicide. I don't know how this rate has changed over time or whether the methods modern humans choose for attempts are more effective than would have been chosen in the past. For example, while men commonly turn to firearms, which are a very effective way to commit suicide, women more often turn to prescription medication overdoses as a method, which overwhelmingly fails.

    #3 is poisoning. While humans have always been around poisons, the sheer number that we keep in our houses, most of types that we didn't evolve to, suggests that this may be a stronger selective factor now than it was during our agrarian days, perhaps comparable to that when we were hunter-gatherers or worse.

    #4 is homicide. We've definitely gotten a lot better at that, a person is far more likely to die from an intentional gunshot wound than a beating or stabbing. Selective pressures: surviving blood loss, mainly. Stronger, thicker bones may help in against low velocity penetrations.

    #5 is other injuries. Again, we're not as likely to suffer from, say "crushed by a mastodon" as an injury, but we've developed plenty of new ways to get killed or maimed in our modern lives.

    Then it gets more complicated on the basis that the issue isn't just about survival of the individual, but their social group as a whole, so even nonbreeding members can have a major impact...

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