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FDA Approves Implantable Vagus Nerve Disruptor For Weight Loss

The L.A. Times reports that for the first time since 2007, the FDA has approved a weight loss device (as opposed to a weight-loss drug), an implantable device called the Maestro Rechargeable System. Using electrical leads implanted just above the stomach and a regulator carried under the skin near the ribcage, the device suppresses signals carried by the vagus nerve. ... The device adopts a variant of a "neuromodulation" technique long used in the treatment of epilepsy: by applying intermittent bursts of electrical current to the vagus nerve, it disrupts the signals that prompt the stomach to relax, expand and prepare for an influx of food. ... The FDA approved the use of the device in adult patients with a body mass index, or BMI, between 35 and 45, who have at least one other obesity-related condition, such as type 2 diabetes.

4 of 168 comments (clear)

  1. Worst idea ever. (Well, one of them). by Anonanonaon · · Score: 5, Interesting

    The vagus nerve does a lot of really cool things which don't get a lot of appreciation.

    Cats purr to self-stimulate it. That's what they're doing when they make that noise. And you can do it also. It orders the mind, creating calm and clarity. When you're affronted with terror or high emotion, "pipe breathe" and within half a minute, you're in the zone, able to think and react with calm precision to high-stress situations. And that's just *one* thing.

    So yeah, let's allow big pharma to cyberman our core nervous apparatus for something as incredibly stupid as a weight loss gimmick.

  2. You gotta be kidding me... by crazybit · · Score: 5, Interesting

    Affecting a nerve to help people regulate their hunger and help them loose weight? There is already a way of doing that and it's called Leptin. Leptin is the hormone that regulates hunger by stimulating receptors in the hypothalamus. When someone suffers from leptin resistance, he will eat all day. The fix? bye bye sugars, bye bye inflammatory foods, bye bye foods with anti-nutrients.

    I lost 100lb resetting my leptin cycle, I stopped eating all day and simply wasn't hungry anymore. No will power, no pills, nothing... the anxiety for food just went away.

    Here is a nice article with 29 scientific references that explains exactly the importance of Leptin Cycle
    And here is a nice video from Stephan Guyenet, Ph.D. explaining it too

    Affecting a whole big nerve instead of changing eating habits is a really really bad idea

    --
    - Human knowledge belongs to the world
    1. Re:You gotta be kidding me... by Cantankerous+Cur · · Score: 5, Informative

      That's bullshit. Obese people have pretty much the same metabolism as skinny people. It's not your "metabolism" that makes you obese, it's how much and what you eat.

      No, it really is quite dependent on biology. There are numerous studies on twins that clearly show that it's governed by far more than just calories in == calories out. http://www.gatsby.ucl.ac.uk/~p... , http://www.nytimes.com/1990/05...

  3. Re:Worst idea ever. (Well, one of them). by Anonymous Coward · · Score: 5, Interesting

    , teenagers jumping off cliffs

    That is an unfortunate side effect of improving someone's condition with severe depression. I've been there, when you're so depressed you don't want to get out of bed or do anything, barely having motivation to eat. Suddenly with an SSRI, and some other alternatives in principle as it isn't just the drug, you have energy and motivation to do things. Some people use that energy and motivation to fix some of the issues and improve their environment to remove things reenforcing their depression, to get their life back in shape. Others who were previous suicidal but too depressed to actually give a damn or motivate themselves to do anything also now have motivation to do what they think they want.