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New Nicotine Vaccine May Succeed Where Others Have Failed

Zothecula writes: If you're a smoker who's trying to quit, you may recall hearing about vaccines designed to cause the body's immune system to treat nicotine like a foreign invader, producing antibodies that trap and remove it before it's able to reach receptors in the brain. It's a fascinating idea, but according to scientists at California's Scripps Research Institute, a recent high-profile attempt had a major flaw. They claim to have overcome that problem (abstract), and are now developing a vaccine of their own that they believe should be more effective.

2 of 178 comments (clear)

  1. Re:Why would you want this? by morcego · · Score: 5, Informative

    You'd still be an addict, just one who could never satisfy his cravings. This sounds more like some sort of torture that an aid to quitting.

    You will always be an addict. I quit smoking over 3 years ago, and I'm still addicted.
    After trying various ways of quitting, I ended up talking to a doctor and got Champix prescribed to be, which ended up helping a lot and making it possible for me to quit. When I did quit, the days I suffered the most were when my body was flushing the nicotine out. For this part, a vaccine like this would have been wonderful. Instead of having cramps and throwing up for 2 days (yes, this kind of abstinence syndrome can happen even with nicotine), and still suffering for several days afterwards, it would have made it much easier.

    So yeah, I do wish this vaccine existed when I quit, 3 years ago, after smoking 2 packs/day for 20 years.

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    morcego
  2. Re:Why would you want this? by morcego · · Score: 4, Informative

    There is nothing wrong about it. Different people will have different levels of addiction. My case, when you get opioid-like withdraw syndrome (cramps and throwing up) is on the opposite end of the spectrum. My case is certainly not the rule, but neither is yours. I don't doubt for a second what you are describing, because it is known to happen. However, it is far from the norm.

    Nicotine is one of the most addictive substances known to man. The numbers on people who try to quit and fail are scary. The numbers of people who quit and start smoking again within the first 2 years are also telling. I don't have those numbers at hand, but they are so widespread that you shouldn't have trouble finding them, if they interest you.

    But yeah, it seems that, regarding nicotine addiction, I've got the short end of the stick, and you've were extremely lucky.

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    morcego