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Photosynthesizing Sea Slugs Steal Genes From Algae

An anonymous reader writes For decades, scientists have puzzled over how a certain sea slug acquires the ability to photosynthesize after ingesting algae. An advanced imaging technique now confirms that the slugs are literally stealing genes from the algae. It's considered the first example of horizontal gene transfer in a multicellular organism.

74 comments

  1. GMO by Anonymous Coward · · Score: 5, Funny

    Holy crap, they're GMO! I demand they be labeled as such right now!

    1. Re:GMO by Anonymous Coward · · Score: 0

      Holy crap, they're GMO! I demand they be labeled as such right now!

      And they also contain DNA!

      And dihydrogen monoxyde!

    2. Re:GMO by Anonymous Coward · · Score: 0

      HOLY FUCK, we are all doomed. Call Faux News!

    3. Re:GMO by Applehu+Akbar · · Score: 0

      This is not the first example of gene transfer in nature, either:
      http://en.wikipedia.org/wiki/H...
        But it's the latest example we can wave in the Luddites' faces.

    4. Re:GMO by dryeo · · Score: 1

      To quote from your link,

      Horizontal gene transfer is the primary reason for bacterial antibiotic resistance

      So it looks like it is a good comparison, the Luddites were right about industrialization making things worse for them, their children and their grandchildren and now the same can be said about horizontal gene transfer.
      Of course the thing with GMO is that it is neutral and can be used for good reasons such as making food more nutritious or bad reasons such as making food keep better even if it means the food is less nutritious or reasons that end up bad like encouraging more pesticide resistance through evolution by horizontal gene transfer.

      --
      https://en.wikipedia.org/wiki/Inverted_totalitarianism
  2. It's not stealing... by sacrilicious · · Score: 4, Funny

    ... it's copyright infringement.

    --
    - First they ignore you, then they laugh at you, then ???, then profit.
  3. Maybe not on slashdot by wbr1 · · Score: 4, Funny

    But I know many multicellular intelligent organisms that have engaged in horizontal gene transfer. Many of them probably shouldn't have.

    --
    Silence is a state of mime.
    1. Re:Maybe not on slashdot by theVarangian · · Score: 0

      But I know many multicellular intelligent organisms that have engaged in horizontal gene transfer. Many of them probably shouldn't have.

      Yes, even humans. It may be a little know example of horizontal gene transfer but if you stay vegan for long enough you start to grow grass on your head instead of hair, thus acquiring the ability to photo synthesize.

  4. Ancient News by Anonymous Coward · · Score: 1

    This has been known for years. I even remember watching a nature doco back in the 90s which went into detail about the creatures.

  5. OMG by anzha · · Score: 2

    Note: all WH40K cosplayers better suit up...

    --
    Do you know why the road less traveled by is littered with the bones of the unwary?
  6. The ol' "horizontal gene transfer" by by+(1706743) · · Score: 2

    Sounds like some sort of euphemism...

    1. Re:The ol' "horizontal gene transfer" by wonkey_monkey · · Score: 1

      Giggidy.

      That word should appear in more scientific papers than it does.

      --
      systemd is Roko's Basilisk.
  7. Re:Oh, my God. by Anonymous Coward · · Score: 0

    They're Democrats!

    Nope! Paparalge

  8. Aha! by Anonymous Coward · · Score: 0

    So this is how they got the ability to produce Adam.

    1. Re:Aha! by Anonymous Coward · · Score: 0

      It's also how I FUCKED YOUR MOTHER! Right up in her vaginal vagina. It was not very tight but it was soooo wet and dripping when she saw my massive schlong! It was most cum worthy! I think she came too, really I don't give a fuck, I got mine.

      One of the glorious things about Rapture is that each man is self-made... so it's clear that you won't get very far ;)

  9. All your base are belong to us by Chikungunya · · Score: 4, Insightful

    I may be too optimistic but this could become a really nice laboratory tool once the exact mechanism of genetic transfer is known and replicated, gene cloning independent from plasmid or simplified transfection would be very useful for genetic engineering. Imagine easily cultured cells that not only can accept various genetic materials but actively incorporate them into their genome, "gene cloning for dummies" kits for one-step protein expression.

    1. Re:All your base are belong to us by __aaltlg1547 · · Score: 2

      There's a well documented case of horizontal inter-species gene transfer from a radioactive spider to a human.

      Another less known case involves a fly and Jeff Goldblum.

    2. Re:All your base are belong to us by Gavin+Scott · · Score: 1

      We have that now. Google CRISPR/Cas9. Like all our cool tools for recombinant DNA, we stole it from existing life forms (bacteria usually).

      G.

    3. Re:All your base are belong to us by Anonymous Coward · · Score: 0

      Article and slashdot abused the study. The horizontal transfer of genes happened in the past, the slug passes those stolen genes on their offspring. They only "steal" the chloroplasts from the algae now as they are unable to make their own.

    4. Re:All your base are belong to us by Tough+Love · · Score: 1

      More to the point, this gets us one step closer to true gillyweed

      --
      When all you have is a hammer, every problem starts to look like a thumb.
    5. Re:All your base are belong to us by Coren22 · · Score: 1

      I can't wait till we can take a pill to do this!

      http://en.wikipedia.org/wiki/L...

      --
      APK likes to ask for responses to the same things over and over. Maybe he just likes the responses?
  10. Re:This Proves GMOs are Safe! by Anonymous Coward · · Score: 3, Insightful

    > It's considered the first example of horizontal gene transfer in a multicellular organism.

    Now that we know horizontal gene transfer happens in nature, that should lay to rest any arguments that GMOs are unsafe, after all it is exactly the same thing just man-made in a lab where it can be tested.

    Because transferring food-making genes into an inedible organism is just the same as transferring poison-making genes into your food.

  11. So if they Ate? by wisnoskij · · Score: 1

    How does that make sense? So if they ate a pig they would turn into a pig-slug? Likely not, I am assuming, then why not just be born with the photosynthesis genes instead of the exact gene needed to copy them and only them from plants? I have heard of similar animals who ingested plankton, and then held the plankton in special translucent "stomachs" that leched the energy out as it was being photosynthesized. Sounds far easier than this method.

    --
    Troll is not a replacement for I disagree.
    1. Re:So if they Ate? by blue+trane · · Score: 1

      Nature laughs at your naive realism. The universe is not only stranger than you imagine, but stranger than you can imagine.

    2. Re:So if they Ate? by jc42 · · Score: 4, Informative

      It might be pointed out that plants' chloroplasts and our mitochondria are now well-understood to have originated as "ingested" bacteria that, rather than being broken down and digested, ended up first as internal symbionts, and were over time transformed into the cells' internal organs. What these slugs are doing is somewhat similar to this, though on a somewhat smaller scale. The slugs apparently only nab a few chromosomes from the algae, and transfer them into their own digestive-system cells.

      But the "first" in the article is a bit different from this: They describe it as the first-known such transfer between two multi-cellular species. Our mitochondria seem to have originated in a single-cell ancestor similar to an amoeba, which incorporated an entire living bacterium as an internal resident. Similarly, plant chloroplasts are believed to have originated as photosynthetic bacteria that were incorporated whole into early algae. In both of these cases, there has been gene transfer from the internal bacteria into the eukaryotic cell's nucleus, leaving the mitochondria and chloroplasts with mostly just the genes needed to do their job, and unable to survive outside their host cell.

      But the slugs took a different route, of separating out the photosynthesis genes from their food's cells, moving the DNA into the slugs' cells, and digesting the rest of the algal cells as food.

      It could be interesting to stick around and see how this works out. Eventually, they might be able to incorporate the photosynthetic mechanism into their own genome, so that when a slug cell divides, it'll get copies of of these genes and won't have to steal them from algae. Plants never never did this, because they maintained their chloroplasts' ability to divide within the plant cell (with a bit of help from the host cell). The slug's approach might turn out better than the plants'. Or maybe it won't. Or maybe it'll just be two different approaches to photosynthesis that both work well enough.

      But we might not know about this for a few more millennia ...

      --
      Those who do study history are doomed to stand helplessly by while everyone else repeats it.
    3. Re:So if they Ate? by jandersen · · Score: 1

      ...originated as "ingested" bacteria that...

      This is probably one of the most exciting, new insights we have achieved in recent decades; but aren't there two equally possible routes for this ingestion? One being that a predatorial cell feeding on these cells at some point stopped completely digesting them, the other being that the mitochondria and chloroplasts were once parasites. I'm not sure which one I think is more likely - perhaps I'd go for the parasite scenario, but it could well be that both routes could have been employed, or that the distinction between predation and parasitism isn't all that clear.

    4. Re:So if they Ate? by jc42 · · Score: 1

      ...originated as "ingested" bacteria that...

      This is probably one of the most exciting, new insights we have achieved in recent decades; but aren't there two equally possible routes for this ingestion? One being that a predatorial cell feeding on these cells at some point stopped completely digesting them, the other being that the mitochondria and chloroplasts were once parasites. I'm not sure which one I think is more likely - perhaps I'd go for the parasite scenario, but it could well be that both routes could have been employed, or that the distinction between predation and parasitism isn't all that clear.

      Indeed. And we have lots of examples in the modern world where such mixed symbioses are visible. We're part of a lot of them. Consider that many of our domesticated species are far more "successful" than their wild relatives, but their price for teaming up with the world's top predator (us) is that we eat most of them. We let enough of them survive and reproduce that, biologically speaking, it's worth the price.

      I wouldn't be at all surprised if it does turn out that our mitochondria started off as both food and parasites for the amoeba-like critters that eventually "domesticated" them and converted them into internal organs. This seems also seems possible for chloroplasts, who could have started as parasites on the larger cells, then eventually adapted to the "you give me minerals and water and hold me up to the sun and I'll give you sugars" role, and had no good reason to ever leave their hosts again.

      But it's possible that we'll never be able to fully sort out how these adaptations happened. There's no natural law saying that they had to leave the evidence behind.

      --
      Those who do study history are doomed to stand helplessly by while everyone else repeats it.
  12. Re:Muh Dick! by Anonymous Coward · · Score: 0

    I'm a 58 year old programmer, my mother will love to have you over for dinner. She's 28 years older than me. When can she expect you for "that special date"?

  13. Re:Muh Dick! by Anonymous Coward · · Score: 0

    I forgot to ask you, do you prefer her teeth in or out? And do you prefer privacy? 'cause she shares a room with a former nun at the nursing home.

  14. Not stealing, stole. by Gavin+Scott · · Score: 5, Informative

    The slugs at some point in their past acquired the genes from algae that are required to maintain/repair the chloroplasts that each one collects from the algae they eat. The horizontal gene transfer is (presumably) not an ongoing process but something that happened in their distant past.

    The baby slugs start eating algae and they digest most of them but they save the chloroplasts from the algae cells and integrate them into their own tissue. Once they accumulate enough of them they basically become solar powered and don't need to eat anymore.

    Normally the chloroplasts would not survive very long without an algae around them to take care of them, but this is where the genes that the slug has that originally came from the algae come into play. The slug is thus able to provide the things that its adopted chloroplasts need to survive for many months.

    Definitely very cool.

    G.

    1. Re:Not stealing, stole. by fraxinus-tree · · Score: 1

      Growing a kid right now. I wish he was at least partially solar-powered. I am OK with the green color.

    2. Re:Not stealing, stole. by Coren22 · · Score: 1

      It could turn you blue...never know.

      http://en.wikipedia.org/wiki/L...

      --
      APK likes to ask for responses to the same things over and over. Maybe he just likes the responses?
    3. Re:Not stealing, stole. by Anonymous Coward · · Score: 0

      Hahahahahaha @ Coren22 http://slashdot.org/comments.p...

  15. Re:This Proves GMOs are Safe! by blue+trane · · Score: 0

    Yes, we should trust Monsanto when they say it's safe, just like we trusted the tobacco companies when they debunked the "smoking causes cancer" myths. Oh wait...

    Why can't Monsanto open source everything? So we can get many eyes to make the bugs shallow?

  16. Re:This Proves GMOs are Safe! by Anonymous Coward · · Score: 0

    You gotta ask yourself the hard questions, boy. How did these slugs acquire this advanced genetic engineering capability in the first place? Were some of them working for Monstanto? Did they have unauthorized access to Monstanto's advanced project results? Have they shared it with someone else, who could be our enema? Did those slugs secretly tap into that knowledge to enhance their bodies? Did they properly license the technology? Are they paying Monsanto what they owe? If they did and they don't, what does our great country do about it.

    And, most importantly, how are YOU going to do your part to help.

  17. This FIRST example? by Cyberax · · Score: 1

    If the reporter thinks it's the first example of horizontal gene transfer then they should go and study molecular biology. It's not even the first example of an animal stealing genes from another kingdom! The bacteria-originated genes were even found in https://en.wikipedia.org/wiki/... - a model organism in biology.

    1. Re:This FIRST example? by Anonymous Coward · · Score: 0

      > The bacteria-originated genes

      You seem to be struggling with the definition of multicellular.

    2. Re:This FIRST example? by Cyberax · · Score: 1

      Uhm... Aphids ARE multicellular.

    3. Re:This FIRST example? by Anonymous Coward · · Score: 0

      >> The bacteria-originated genes
      > Aphids ARE multicellular.

      What part of "bacteria" do you fail to comprehend?

      Seriously you are just one of those autistic fuckwads who thinks he's superior for deliberately missing the point. Stop masturbating in public already, no one is impressed which is why no one modded you up for your genius insight.

  18. Re:This Proves GMOs are Safe! by Cyberax · · Score: 4, Informative

    Erm... Monsanto GM modifications are open source. The sequence of nucleotides and the method of their insertion is clearly described in these patents: https://www.google.com/patents... , https://www.google.com/patents... and other related patents. Feel free to use them, they are expired as of the last year.

  19. Fuel for skeptics? by Tablizer · · Score: 1

    A creationist could argue that (apparent) gene transfer means evolution provides no consistent predictions. If things change suddenly or traits hop between category branches, then evolutionists can simply claim "gene transfer". If they change gradually, then they claim traditional natural selection.

    Of course there is more to the net evidence, but the prediction-ability argument is weakened by gene hopping since it can be invoked to "explain away" a wide range of different observations.

    A natural world that provides a wide variety of characteristic transfer options becomes less distinguishable from engineered changes. No camera was there to actually catch the gene hops or mutations in the act. We can only verify that they moved or changed after the fact. Nature is surprisingly flexible.

    1. Re:Fuel for skeptics? by DanielOom · · Score: 1

      The evidence implies that the slugs violate Darwin's laws of Evolution in order to get some advantage in their struggle for survival, but they equally violate the laws that the Creator decreed.

  20. Re:This Proves GMOs are Safe! by Anonymous Coward · · Score: 0

    thats not open source. thats public domain.

  21. Re:This Proves GMOs are Safe! by ChromeAeonium · · Score: 3, Insightful

    The Bt gene is a 'poison making gene' in the same sense that grapes are poison berries; just because a thing harms one organism (in the case of Bt, lepidopterans and coleopterans and in the case of grapes dogs) does not mean it hurts you. The Bt toxin is very well understood; to imply it is dangerous to humans is simply dishonest.

  22. You insensitive clod by Anonymous Coward · · Score: 0

    My mother was killed by a photosynthesizing slug, you insensitive clod!

  23. Re:This Proves GMOs are Safe! by ChromeAeonium · · Score: 2

    So one is saying trust Monsanto (or Syngenta or Pioneer or any of the other seed companies that always get neglected for some reason). I am, however, saying the evidence is overwhelming that genetically engineered crops are safe and effective (and yes, contrary to the conspiracy theories claiming that Monsanto somehow owns the concept of genetic engineering, this includes research that has nothing to do with corporations) and that genetic engineering has been thoroughly demonstrated to be a useful tool for crop improvement. Those are two totally different statements; don't pretend otherwise.

    Why can't Monsanto open source everything?

    Why can't they work for free you mean? I can think of a few reasons.

    You know, if you really want more GE crops that are free to use besides the ones going off patent, and I for one sure do, then you should demand that the scientifically unjustified over-regulation of GE crops be reworked to facilitate more publicly funded GE crops. Thus far, only one university developed GE crop has been released: the Rainbow papaya, developed by the University of Hawai'i. There is also Bt eggplant in Bangladesh which is non-corporate. There's plenty of research, but no ability to bring it to the market anymore thanks to over regulation. There's something very wrong when university research cannot be used and only corporations can overcome the regulatory hurdles.

  24. Now imagine all the super power they would get by ruir · · Score: 1

    If eating McShit food and pizzas all day.

  25. Re: This Proves GMOs are Safe! by Anonymous Coward · · Score: 0

    Mod parent and grandparent the fuck down.

  26. If only by sjames · · Score: 0

    If only we could make that work for humans.

  27. Re: This Proves GMOs are Safe! by Anonymous Coward · · Score: 1

    Mod parent, grandparent and grandgrandparent horizontally.

  28. Other Adapting Animals by Anonymous Coward · · Score: 0

    Primal Zerg!!!!

  29. Re:This Proves GMOs are Safe! by smooth+wombat · · Score: 1, Redundant

    So what you want is for someone else to do all the work then hand it over to you? Stop being a leech and do your own research.

    This shit costs money.

    --
    We will bankrupt ourselves in the vain search for absolute security. -- Dwight D. Eisenhower
  30. Re:This Proves GMOs are Safe! by Applehu+Akbar · · Score: 1

    Golden rice is open source and developed in response to a specific humanitarian need, but the lack of any association with Monsanto hasn't stopped the flat-earty lobby from ripping up fields of it out of pure spite.

  31. Oddly enough by azav · · Score: 1

    I was taught this in my college Marine Biology classes in the late 1980s.

    How has it taken this long for it to be discovered again? Were the 1990s the dark ages?

    --
    - Zav - Imagine a Beowulf cluster of insensitive clods...
    1. Re:Oddly enough by Coren22 · · Score: 1

      I believe it is the mechanism they discovered, not that it happened.

      --
      APK likes to ask for responses to the same things over and over. Maybe he just likes the responses?
    2. Re:Oddly enough by Anonymous Coward · · Score: 0

      Hahahahahaha @ Coren22 http://slashdot.org/comments.p...

  32. Re:This Proves GMOs are Safe! by Sique · · Score: 1

    Golden rice solves just the wrong problem. Yes, there are people who don't get enough Vitamine A, but to solve it by increasing the price of the only food they can afford does not exactly solve this problem. There are cheaper rice crops with higher yield than Golden rice.

    --
    .sig: Sique *sigh*
  33. Re:This Proves GMOs are Safe! by Anonymous Coward · · Score: 0

    The Bt gene is a 'poison making gene' in the same sense that grapes are poison berries; just because a thing harms one organism (in the case of Bt, lepidopterans and coleopterans and in the case of grapes dogs) does not mean it hurts you. The Bt toxin is very well understood; to imply it is dangerous to humans is simply dishonest.

    Is the Bt gene dangerous to honeybees? Keep in mind they pollinate in order of about 60% of what we eat ...

  34. Luminescent Biomass by Anonymous Coward · · Score: 0

    Only one question remains: Which one first, Cyclone Trap or Insect Swarm?

  35. Re:This Proves GMOs are Safe! by ChromeAeonium · · Score: 1

    but to solve it by increasing the price of the only food they can afford does not exactly solve this problem

    That's not at all the point of Golden Rice. It is supposed to act as a way to improve the nutritional quality of rice for those who cannot afford anything else, not be a luxury food.

    There are cheaper rice crops with higher yield than Golden rice.

    Golden Rice doesn't have a set yield. The idea is to breed it into locally adapted varieties so that they retain virtually all of the same genes, but produce the extra nutrition.

  36. Re:This Proves GMOs are Safe! by blue+trane · · Score: 1

    Food companies used to use formaldehyde as a preservative. Wasn't it obviously safe and effective, as the research of the day proved? Can you think of any other examples where the research overwhelmingly said something was safe and effective, but it wasn't?

    Are you an anti-vaxer? Doesn't the research overwhelmingly show that vaccines are safe and effective? Why doesn't everyone accept that research?

    Do you think that the research shows overwhelmingly that global climate change is human-caused? How many disagree, and fight tooth and nail against the conclusions of that research?

    "Why can't they work for free you mean? I can think of a few reasons."

    Does Red Hat work for free? Do Google Chrome developers?

    If the research is so overwhelming, why is Monsanto afraid to label foods GMO? If they can prove that their modifications are safe, why not let me know on the label?

    Once again: didn't the research show that tobacco didn't cause cancer at one time? Didn't tobacco companies fight against warning labels? How is the situation with Monsanto now not eerily similar?

  37. Re:This Proves GMOs are Safe! by Bengie · · Score: 2

    Oxygen is toxic, water is toxic, nitrogen is toxic. Please define the safe allowance of such poison and how much is actually ingested.

  38. Makes me wonder if.. by Anonymous Coward · · Score: 0

    It makes me wonder if lateral (horizontal) gene transfer across species is/was much more common than we currently think it is.

    For these current findings, photosynthesis is a fairly easy phenotype to observe (it doesn't require a lot of advanced tools to know it is there). So to show that it occurred, someone would likely do a search across both genomes. If they find a match, then their hypothesis has a positive test. Fortunately they did get a match with enough statistical confidence to show that the genes' matched, but I bet it wasn't an exact match and it was probably aided from other known sequence-to-gene mappings. The problem applying this more generally is that over, many, many generations mutation can make the outcome of a gene match less confident, and thus hard to find.

    Say someone tries to do a search for possible lateral (horizontal) bacterial genes in the human genome, for bacteria genes that evolved after we forked away from our "common ancestor." What would be the likelihood that they would find a match? --it would, however, require that we have sequenced these ancestral genomes that may not exist anymore, or are very hard to physical locate. I somewhat doubt we have this data, as the required quantity we would need would be too vast.

    For example, our current state is that, cell to cell (not body mass to collective mass), we are made up of more bacteria than human. And, each human has a very unique set of bacterial species in them (more unique than a fingerprint). That is way too many species to have know the genomes and topological relationships with all humans.

    So, say we do have genes from bacterial genes seeping into our gene pool. (1) They would be very difficult to gene match to know for sure, and (2) maybe this explains why people react differently to medications? Or why have a wide range of different disease predictors/risks.

  39. Re:This Proves GMOs are Safe! by Sique · · Score: 1
    You don't get me, right? People eat rice, because this is the cheapest food available. Some people can afford only rice and nothing else. Those people thus have a quite unbalanced diet, and Vitamine A is one (but not the only) nutritient that is underrepresented.

    To solve this problem by adding Vitamine A to the rice is misguided. The diet is still unbalanced, and just adding more and more nutritients to rice will just make the crop yield less in general, being thus more expensive, and people will still be poor and not able to afford anything but rice - and in general more of the old fashioned white rice as this one will still be cheaper.

    It would make more sense to empower those people to earn more money to pay for a much more balanced food.

    --
    .sig: Sique *sigh*
  40. Re:This Proves GMOs are Safe! by kurzweilfreak · · Score: 1

    How exactly are they "increasing the price of the only food they can afford" by literally giving Golden Rice away for free?

    --

    kurzweil_freak

    5th Kyu Genbukan Ninpo/KJJR student

    Be the darkness that allows the light to shine.

  41. Re:This Proves GMOs are Safe! by kurzweilfreak · · Score: 1

    It's a lot easier to empower people to earn more money when a large portion of their kids aren't going blind and dying. Just because Golden Rice isn't a magic bullet that solves all of this population's problems doesn't mean that it doesn't help.

    --

    kurzweil_freak

    5th Kyu Genbukan Ninpo/KJJR student

    Be the darkness that allows the light to shine.