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Ebola Lurked In Cured Patient's Eye

An anonymous reader writes: During the Ebola outbreak last year, Dr. Ian Crozier was infected. He was eventually airlifted to Emory University for treatment, and a couple months later he was cured of the disease — or so physicians thought. Not long after he was released, his left eye began bothering him. His sight faded, and he felt intense pressure and pain in his eye. Examination of the eye found it teeming with Ebola. His doctors were surprised. Cured patients frequently deal with health issues long after the virus is gone, but this adds a new dimension to the course of the disease.

Doctors say Crozier posed no threat to others through casual contact; the virus did not exist in his tears or on the surface of his eye. But in addition to the new symptoms, his eye turned from blue to green. And doctors had to rush to disinfect the exam area used for what they thought was an Ebola-free patient. Research is ongoing to determine whether and how to protect from this lingering ebola infection. One theory suggests the virus survived, but was damaged somehow. Crozier was treated with antiviral drugs, and his eye improved, but doctors aren't sure whether the drug actually helped. Either way, it's made the medical community realize this is a longer battle than they had thought.

65 comments

  1. Coming soon by Anonymous Coward · · Score: 0

    Soon to be released as a movie: Attack of the Killer Eyeballs.

    1. Re:Coming soon by MobileTatsu-NJG · · Score: 1

      Soon to be released as a movie: Attack of the Killer Eyeballs.

      Not to nitpick, but it's actually "Attack of the The Killer Eyeballs".

      --

      "I like to lick butts!" by MobileTatsu-NJG (#32700246) (Score:5, Informative)

    2. Re:Coming soon by davester666 · · Score: 0

      Fools.

      It's "Attack of the The Killer Eyeball"

      --
      Sleep your way to a whiter smile...date a dentist!
  2. already done... by turkeydance · · Score: 2

    28 Days

    1. Re: already done... by Anonymous Coward · · Score: 0

      Correction, 28 weeks later.

  3. New cursing (like a curse, not swearing) by Anonymous Coward · · Score: 0

    Dissatisfied with "Die in a fire!" or "Eat a bag of dicks!"? Try "Get Ebola in your eye!" It's such lovely news. I probably won't sleep this month, looking at every little floaty thing in my vision as possibly being ebola.

    1. Re:New cursing (like a curse, not swearing) by Anonymous Coward · · Score: 3, Insightful

      There are worse things out there...

      (link is not for the squeamish...)

    2. Re:New cursing (like a curse, not swearing) by demonlapin · · Score: 1

      Haha. When I was in med school, we got a lecture on arthropod-borne diseases from the state entomologist. The botfly is not the only fly that does this, just the only one that does it commonly in humans. Wild animals at certain times of year have very high parasite loads.

  4. The more we learn about viruses... by tomhath · · Score: 4, Insightful

    All the research related to HIV taught us a lot, but this kind of thing makes it obvious that we don't know nearly as much about viruses as we thought.

    1. Re:The more we learn about viruses... by Anonymous Coward · · Score: 1

      Or at least that a lot of people make too many assumptions about [deoxy]ribonucleic acids. I think it's well understood that viruses can mutate, and can be vectors of all types of malady. Evolution itself is the issue in question, and the reason it's not better understood is mainly because there are zealots making sure it stays that way. (And always have been)

    2. Re:The more we learn about viruses... by Anonymous Coward · · Score: 5, Informative

      Huh? It was already known that the eye is a potential reservoir for viruses. The inner eye has what's called "immune privilege". That is, to protect against damaging inflammation in the eye, the inner eye has a protective membrane impermeable to normal immune cells. If a virus manages to make it into the eyeball, it's more-or-less protected from the body's normal immune system.

      See http://en.wikipedia.org/wiki/Immune_privilege

      Doubtless there's a ton we don't know about our biology and the biology of viruses, but this wasn't one of them. The only gap in knowledge here was knowing whether the suspicions were correct--that Ebola could persist in the eye. It was long suspected, but because most Ebola patients die, and outbreaks were so quickly contained, there were never enough survivors to study. But now there are thousands of survivors.

      You know, all of this is very well discussed in the news articles.

    3. Re:The more we learn about viruses... by Anonymous Coward · · Score: 0

      Actually, what's it's revealed is that you're much more susceptible to propaganda than you thought.

      You really believe this cockamamie, bullshit story about Ebola?

      Isn't it funny how all the news coverage of this "massive outbreak" died immediately after the elections? With only the occasion news story popping up to continue certain parts of the storyline (that's what it is--a dramatic story.)

      The reason his eyes changed from blue to green is because he took out his eye color changing contact lenses.

      He's an actor. A paid actor....just like the "clipboard guy." (Look it up.)

      You've been duped.

  5. I have mod points by Cafe+Alpha · · Score: 1, Offtopic

    but there's no "Oh God, no!" mod.

  6. ebola stigma by phorm · · Score: 2

    This isn't going to do well for the stigma already suffered by ebola survivors. I believe that the survivors are generally thought to be immune to further infection as well, so it's a bit scary that the virus can still find repositories in the body where it can hang out for longer periods of time.

    1. Re:ebola stigma by NormalVisual · · Score: 4, Insightful

      I believe that the survivors are generally thought to be immune to further infection as well, so it's a bit scary that the virus can still find repositories in the body where it can hang out for longer periods of time.

      It's not anything particularly new - we've known for decades that anyone that's had chicken pox still has the dormant virus in a number of nerve ganglia near the spine, and sometimes it reactivates and causes shingles.

      --
      Please stand clear of the doors, por favor mantenganse alejado de las puertas
    2. Re:ebola stigma by cookiej · · Score: 1

      Well, a stigma deserved, it would seem. I wonder where that Nurse is that refused to isolate herself because she was "cured".

    3. Re:ebola stigma by Anonymous Coward · · Score: 3, Informative

      She wasn't "cured", because she never had Ebola to begin with. She tested negative for the virus and was asymptomatic. It was the stupid politicians that overrided the doctors' conclusion that she wasn't infected.

    4. Re:ebola stigma by CrimsonAvenger · · Score: 5, Interesting

      It's not anything particularly new - we've known for decades that anyone that's had chicken pox still has the dormant virus in a number of nerve ganglia near the spine, and sometimes it reactivates and causes shingles.

      And speak of the devil. My chicken pox virus was apparently hiding in the nerves associated with my left hip. Two weeks ago, I woke up with my left hip hurting. Later that day when I bitched about it, the wife looked at my behind and said "you've got shingles". Doctor agreed.

      It's almost done. Left hip only hurts a little, most of the pox is scabbed over or gone. Should be fine Real Soon Now.

      And as soon as I'm over this, have to get shingles vaccine. Which they only give to people at high risk for same. Having gotten it at a relatively young age (young by Shingles standards), I now qualify as being "at high risk for Shingles" according to the Doc....

      A bit more on-topic, Ebola has now established that it can establish a reservoir in a survivor, so ANY of the people who survived the latest round is a potential carrier.

      Plus Ebola has now established that it can transmit sexually (ebola is now a VD), if only rarely.

      So does this mean all ebola survivors need to be extremely careful about who they screw, and likewise anyone who might feel the urge to bang an ebola survivor?

      --

      "I do not agree with what you say, but I will defend to the death your right to say it"
    5. Re:ebola stigma by currently_awake · · Score: 1

      The virus appears to be good at hiding in non-blood body fluids. That might include spinal fluid, brain fluid, and several internal organs. Maybe this is how HIV survives so well.

    6. Re:ebola stigma by NormalVisual · · Score: 2

      Shingles sucks, that's for sure. I had it make a visit via my trigeminal nerve when I was 29. The eye doctor was freaking out for a little while, but fortunately it ran its course without any eye complications.

      --
      Please stand clear of the doors, por favor mantenganse alejado de las puertas
    7. Re:ebola stigma by Anonymous Coward · · Score: 1

      it's a bit scary that the virus can still find repositories in the body where it can hang out for longer periods of time.

      The eye has something like the blood/brain barrier to isolate it from the rest of the body and keep infectious agents out. Unfortunately, if something gets through that barrier, it can also hide out there from medications and some elements of the immune system.

    8. Re:ebola stigma by dbIII · · Score: 1

      It was the stupid politicians that overrided the doctors' conclusion that she wasn't infected.

      Correct me if I'm wrong, but wasn't it the prick who shut down the tollbridge up to stupid games again?

    9. Re:ebola stigma by Chris+Mattern · · Score: 1

      Apparently you skipped over the part where the patient was described as "not contagious".

    10. Re:ebola stigma by cookiej · · Score: 1

      Apparently you skipped over the part where he was declared "ebola free" by the same group who are declaring him not contagious.

      My issue is that this "cure" appeared recently and from my (admittedly layman's) perspective, it hasn't had enough time to prove it's completely effective. And given the risks involved if someone is wrong, it seems foolhardy to just trust that it will work.

      And when I read that the doctors are "stumped" as to why the disease wasn't completely eliminated, it scares the hell out of me. This isn't AIDS. It's faster and far more easily and casually contracted. Not to be trifled with. Until people have been truly "Ebola free" and not contagious for years, I think precautions are warranted.

    11. Re:ebola stigma by Anonymous Coward · · Score: 0

      Mine breaks out under heavy stress. Thankfully it has symptoms (a sort of a gripping sensation in the rear right of the lower back) which essentially tell me that I'm under heavy stress, effectively helping me prevent a second burn-out.

    12. Re:ebola stigma by Anonymous Coward · · Score: 0

      Ebola is actually about as hard to get as HIV. Both (probably) need contact with bodily fluids, most likely fluid-on-fluid contact or ingestion. There was one study that said Ebola was transmissible by air in monkeys, but that's never been shown in humans, I'm pretty sure. This outbreak was so bad for two main reasons: the population didn't trust the doctors, and would actively do things they were told not to, and there was really shitty health infrastructure there.

  7. At least it wasn't in his penis or scrotum. by Anonymous Coward · · Score: 0, Insightful

    Having an infected eye is not good at all. But at least most people have two functioning eyes. A much greater risk would be to a singular organ, such as the penis or the scrotum. A diseased penis leaves very few options for treatment. And although most men have two testicles, they only tend to have one scrotum. Testes require a scrotum, so damage or loss to the scrotum itself often means death of one or both of the testicles. There is no fallback when dealing with the penis and the scrotum.

    1. Re:At least it wasn't in his penis or scrotum. by Anonymous Coward · · Score: 0

      There is no fallback when dealing with the penis and the scrotum.

      Not a guaranteed solution, but phalloplasty is option.

  8. So what is the upshot here? by Anonymous Coward · · Score: 0

    I got the impression from TFA's that if Ebola survivors are experiencing ailments due to "post-Ebola" syndrome, then they're not really free of the virus. They're immune systems may be keeping the virus in largely in check, but since they still harbor the virus in their body, they're still contagious, right?

  9. Meanwhile on the loudspeaker by TheCreeep · · Score: 5, Funny

    We have detected ebola in patient's eye.
    Under no circumstances is anyone to make eye contact with the patient
    I repeat, no eye contact.

    1. Re:Meanwhile on the loudspeaker by Mr+D+from+63 · · Score: 2

      And keep your eyes off my wife too!

    2. Re:Meanwhile on the loudspeaker by leathered · · Score: 1

      Do not stare at Ebola patient with remaining eye.

      --
      For all intensive porpoises your a bunch of rediculous loosers
    3. Re:Meanwhile on the loudspeaker by rubycodez · · Score: 1

      well there was that weird fetish couple years back in Japan....let's leave the eyeball licking to geckos eh?

    4. Re:Meanwhile on the loudspeaker by slew · · Score: 1

      We have detected ebola in patient's eye.

      Under no circumstances is anyone to make eye contact with the patient

      I repeat, no eye contact.

      Unless of course you engage in vodka eyeballing for protection ;^)

    5. Re:Meanwhile on the loudspeaker by The+Evil+Atheist · · Score: 1

      No, there wasn't. It was never a fetish. It's an urban myth.

      --
      Those who do not learn from commit history are doomed to regress it.
    6. Re:Meanwhile on the loudspeaker by Anonymous Coward · · Score: 0

      So you'll need to watch EVERYONE who has a "twinkle in their eye" now.

      DAMN. So much for sex tonight. (Wait ... That's just the latest excuse I can use. Who am I fooling?)

    7. Re:Meanwhile on the loudspeaker by rubycodez · · Score: 1

      not an urban myth, posted videos, photos on street and eye infections were in the news at the time in Japan.

    8. Re:Meanwhile on the loudspeaker by The+Evil+Atheist · · Score: 1

      http://www.snopes.com/media/go... No, those posted videos and photos and reports of news in Japan were all fakes. There's a difference between actually seeing it on the news in Japan and hearing that it's on the news in Japan.

      --
      Those who do not learn from commit history are doomed to regress it.
  10. Ebola Zombies with Green Eyes; Film at 11... by Grog6 · · Score: 4, Insightful

    This is the start; a simple mutation that allows it to spread unnoticed throughout the population...

    "I totally got this eye infection, but it made my eyes this really rad color of green! Uh...Do you Smell Brains?!!" :)

    --
    Truth isn't Truth - Guliani
    1. Re:Ebola Zombies with Green Eyes; Film at 11... by Anonymous Coward · · Score: 0

      It should be easy to detect. How many people of African descent have green eyes?

    2. Re:Ebola Zombies with Green Eyes; Film at 11... by Cafe+Alpha · · Score: 1

      His eyes started out as blue.

    3. Re:Ebola Zombies with Green Eyes; Film at 11... by rubycodez · · Score: 1

      since the whole human race came out of west africa.....

    4. Re:Ebola Zombies with Green Eyes; Film at 11... by Chris+Mattern · · Score: 1

      Actually, they came out of east Africa

    5. Re:Ebola Zombies with Green Eyes; Film at 11... by rubycodez · · Score: 1

      Actually, even by your link it looks like there is mounting evidence North Africa might well be the actual launch point of migrations. Well anyway, I apologize for reverting back to old theory and forgetting "recent" findings like an old fart

  11. Mod parent up (+1 Insightful) by Anonymous Coward · · Score: 0

    nt

  12. it wasn't because she was cured by Anonymous Coward · · Score: 1

    It's because she never had it to start with. She was told to enter quarantine as a precaution, she didn't do so.

    A judge sided with her.

    For what it matters, she was right. She never had it.

  13. Same guy? by Anonymous Coward · · Score: 0

    Is this the same guy, who when he left the hospital, said basically jack about the medical staff and everything was about how prayers and god healed him?

  14. Engineers? by Anonymous Coward · · Score: 0

    Please tell me I wasn't the only one to think of Prometheus.

  15. Cartman would say by Virtucon · · Score: 2

    Don't give me pink eye you goddamn hippies!

    --
    Harrison's Postulate - "For every action there is an equal and opposite criticism"
  16. Why Just The Eye? by Anonymous Coward · · Score: 0

    Ebola can be hiding anywhere in the body!
    In your nose, your mouth, your brain....brains...hmmmm...brains.....

  17. Wow... by Anonymous Coward · · Score: 0

    Wow... I bet he didn't see that coming.

  18. Dear /. by Anonymous Coward · · Score: 0

    Why is there no Score:-2 for posts like this?

    1. Re:Dear /. by FatdogHaiku · · Score: 1

      Why is there no Score:-2 for posts like this?

      Set your account to browse at 0...

      --
      You have the right to remain sentient. If you give up the right to remain sentient, you will be elected to public office
  19. Re:Coming soon: horror aplenty by TheRealHocusLocus · · Score: 2

    You know those awful Hollywood movies, where the needle just has to go into the eye.
    NO Not the EEYEE! Yes, the eye.
    Has to be a needle. Has to go in the eye.
    So eyeballs are the new bat placentas.
    Females give birth upside down, and the goo drops down.
    That's just great. Things are looking up.

    --
    <blink>down the rabbit hole</blink>
  20. that makes it... by Anonymous Coward · · Score: 0

    eyebola

  21. Thanks for this story by nitehawk214 · · Score: 1

    I wasn't planning on sleeping tonight anyhow.

    --
    I'm a good cook. I'm a fantastic eater. - Steven Brust
  22. Wait... by rebelwarlock · · Score: 1

    Research is ongoing to determine whether and how to protect from this lingering ebola infection.

    So they're also considering just fucking off and leaving him be?

    1. Re:Wait... by Anonymous Coward · · Score: 0

      No. I saw Ian Crozier give the final keynote speech at the ophthalmology congress, ARVO on Thursday. He has a great team of medics following him at Emory, and of course (no pun intended) they're going to keep an eye on him. Dr Crozier, the hero, is going back to Africa to continue working as an Ebola medic. Legend.

  23. Not news. by pigwiggle · · Score: 1

    As another commenter has pointed out, this is not news. It is well known that viruses can cause Uveitis. Several are well known for it. Others not. In the absence of a rheumatological disease, unresolved Uveitis is presumed to be viral. A couple of years ago I had what I thought was the flu. It started to go away, I was on the mend, then it destroyed me. Several days in bed, 107 fever, rigors, probable encephalitis. 6 weeks later I developed Uveitis. My doctor has yet to identify a virus. Twice I've had PCR of the fluid in my eye looking for the usual suspects. No luck. So now I'm on a 6 month course of antivirals in the hope of killing whatever it is.

    --
    46 & 2
  24. And it can cause Uveitis. by pigwiggle · · Score: 1

    Which is what Ebola did to this guy.

    --
    46 & 2
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  26. Etox by sacdelta · · Score: 1

    The newest cosmetic treatment coming soon.

    Tired of those drab blue eye? Make them green with Etox.

    --

    Brought to you by: "Al"toids - the curiously weird mint.