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Studying the Roots of Individuality

An anonymous reader sends an article from Quanta Magazine about research into individuality — how behavior varies (or doesn't) when genetics and environment are as similar as possible. Scientists are taking various strains of fruit fly that are genetically almost identical (the result of extreme inbreeding) and raising them alone in environments that are exact copies of each other. Then they run the fruit flies through a series of decision-making tests to see how varied their responses are. Some fruit fly strains show a high degree of variance for tasks like navigating a maze. Other strains show almost no variance, suggesting there's a genetic component to individuality. The scientists also found that manipulating a certain set of neurons in the fruit flies's brains could increase the variation in choices they make. One theory suggests that evolution tends to select for genes that increase individuality by making it more difficult for predators to predict what the prey will do next.

42 comments

  1. randomness of cosmic rays by turkeydance · · Score: 2

    they dissect the DNA. Good Luck!

  2. Read this article by Anonymous Coward · · Score: 1

    and then tell me the simulation theory isn't a perfectly valid possibility.

    -dk

  3. Study could also prove effects of Drugs on Humans by ZippyTheChicken · · Score: 3, Interesting

    Many people believe that the use of drugs whether legal or illegal have no effect on your thoughts and decisions. This is a common belief among people who use marijuana but consider the millions of children who are on prescribed drugs like Ritalin. Anything that alters the way your mind functions will have an effect on your thought processes. Whether its a glass of wine, crack cocaine or a pharmaceutical. All you have to do is watch the disclosures on almost any pharmaceutical commercial and you will see warnings that are very dramatic but true. One product used to help people quit smoking is known to cause suicides. While it is interesting to watch studies on fruit flies .. we should all understand its application in our lives. Anything that alters your perception of reality whether prescribed or self applied will cause changes in your thought patterns. Most often those changes are negative in promotion of a health and well being but that is not to say that small numbers of people can't be helped by products like anti psychotics.. keep this in mind the next time you have a drink to combat the harsh world out there.. or pop a pill to substitute one addiction for another... or smoke some weed because you just don't want to give a ##### for a while.. because its changing you for the worse.

  4. PNAS and PDFs by Anonymous Coward · · Score: 1

    It is really annoying how PNAS is trying to get everyone to use their Beta Eyeball viewer so you can't get a pdf from the article page. I tried it, didn't care much for the split screen and suspected it would somehow be modified to stop me from downloading and saving for myself. Bring back the pdfs.

    Also, I like this paper. They correctly use p-values in figure 1, there is a real null hypothesis.

  5. Agenda. by Anonymous Coward · · Score: 0

    I hope this isn't going to be swooped down on by scientists with an agenda, like in intelligence - where on the one side you have people who've invested in a lifetime assumption of "g", and see more and more evidence that it correlates with success even as more and more workplaces impose artificial entrance tests which look at "g"; and on the other, we have people who are terrified with the idea that people with different coloured skin might perform slightly differently at stuff, even if that difference means nothing until society wants it to.

    1. Re:Agenda. by Anonymous Coward · · Score: 0

      Everyone educated beyond high school has the most to fear from racism being proven right. This will be a truth that for the sake of society will have to be supressed under pain of summary execution.

  6. Re:Study could also prove effects of Drugs on Huma by Guy+From+V · · Score: 1

    Is it reality that alters perceptions or perceptions that alter reality? Are we lost in the mix or are we a non-sequitur? Do elements sharing outer valence shells determine reality or is it God? :bubbling noise:

  7. On Individuality by causality · · Score: 2

    What I observe with the majority of people: they are fully capable of being free-thinking individuals, but the main way they use this capability is to follow the crowd.

    With herd animals that are prey creatures (i.e. cattle, sheep) this makes sense in terms of survival. There is safety in numbers. Stray from the herd, and you get targeted by ever-present predators.

    With humans, who are at the top of the food chain and generally have no natural predators, it's just a form of cowardice. I'm not sure the DNA of fruit flies is going to provide a satisfying explanation here, at least not one that can be extrapolated to include people, fascinating though it may be.

    --
    It is a miracle that curiosity survives formal education. - Einstein
    1. Re:On Individuality by slew · · Score: 4, Interesting

      I don't know if simply following the crowd is a form of cowardice, more often an expression of human make as social beings.

      You may argue that humans are at the top of the food chain, but more often than not, it takes a village to assure long term survival and being social beings is one behavior designed to gain acceptance in a village.

      On the other hand, we tend to detest what is too similar to ourselves, so in a sense humans are like skyrmion (bosons that sometimes exhibit fermion exclusion statistics). At least that's one way to look at it if you extrapolate things from the behavior of sub-atomic particles ;^)

    2. Re:On Individuality by Anonymous Coward · · Score: 1

      With herd animals that are prey creatures (i.e. cattle, sheep) this makes sense in terms of survival. There is safety in numbers. Stray from the herd, and you get targeted by ever-present predators.

      That may have something to do with this work. They saw that while on average a group of flies is equally likely to turn right or left, different individuals were biased to turn one way more often than the other (eg right 75% of the time). So in a large group of flies there would be ~50% turning one way or the other at any given time, this would result in the swarm appearance that we see (imagine seeing a cloud of flies all circling in the same direction, which does not happen).

      The question is, what makes one fly get biased towards turning right vs left? At first I would think it was some kind of learning, the flies were rewarded somehow for turning right early on so they formed that habit, others for turning left so they formed that habit (This is old, old-school psychology before they started doing weird stuff: https://en.wikipedia.org/wiki/Law_of_effect). However, there does not seem to be any reward or punishment involved here. On the other hand, maybe this learning occurred earlier since the flies were already 4-8 years old at the time of the experiments. They should watch newly hatched flies to see what they do. Also a good summary chart would be to create a string of RLLLRRRL from the data, then associate red and blue with the two directions. This can then be used to show the pattern of turns via colored boxes for each fly.

      From the learning perspective, we should also ask why these flies keep exploring the y-mazes used in the experiments at all? After a few times it seems they should realize nothing is there and simply conserve energy.

      This is the best bioscience I've seen posted to slashdot in a long time. Thanks Soulskill, even though you are wrong in the summary when you write "Other strains show almost no variance". One strain showed less variance than the others, but this was still much more than expected if there was no bias.

    3. Re:On Individuality by Anonymous Coward · · Score: 0

      Someone needs to conduct a study to determine the exact ratio between crowd size and the collective IQ of the particular crowd.in question. From just observing the phenomenon it seems like the larger the crowd the stupider they become.

    4. Re:On Individuality by Immerman · · Score: 2, Insightful

      You forget though that humans spent most of our evolutionary history as prey animals. It's only in the last few hundred millenia that we've begun to ascend to "dominant predator" status, and much of that ascension has been due directly to our much enhanced ability to cooperate and share knowledge within our tribal groups. We are very much a herd animal, and as such a predilection to herd-animal instincts is entirely reasonable.

      --
      --- Most topics have many sides worth arguing, allow me to take one opposite you.
    5. Re:On Individuality by Anonymous Coward · · Score: 0

      Flies live for years now?

    6. Re:On Individuality by Anonymous Coward · · Score: 0

      It has been known how to genetically alter flies so that they live 100x longer than usual for awhile now, just mutate only nucleotide 359823 from T->C without changing anything else.

    7. Re:On Individuality by Oligonicella · · Score: 1

      Provide a cite or you're talking out your ass. Best they've done that I can find is 3x.

    8. Re:On Individuality by Anonymous Coward · · Score: 0

      It was a joke because I accidentally wrote years instead of days. I doubt anyone could manage to mutate only one basepair without messing up something else at this point.

    9. Re:On Individuality by Anonymous Coward · · Score: 0

      Same AC. Building on the psych perspective more, lets say there is some obstacle to observing the turning behavior of flies starting at birth and in their home housing, etc. While that would be ideal, instead I think they should set up an experiment where they are rewarded eg 75% of the time for turning right and 25% for turning left, then see if the biased turning can be recapitulated. This may be a case of probability matching (https://en.wikipedia.org/wiki/Probability_matching).

    10. Re:On Individuality by Anonymous Coward · · Score: 0

      The smarter/smartest individual will always have the possibility to be smarter than the average. Duh.
      The larger population size, the less extreme the average will tend to be. It's so by pure mathematical definition, not by any external observable phenomenon or model of such.

      It's very easy to be blindsided by the illusions created when comparing statistical results from different sampling sizes. You'd need to normalize the scale, and even then you are left with some unresolvable traces of sampling bias that create subtle inconsistencies.

      There's also logistical limitations on crowdsourced group-think. Crowds can become "smarter" by electing smart representatives or even using technology to overcome practical limitations of communications and logic.

      So yes, your perception is probably correct in many cases. Could it be any other way though?

  8. Re: Study could also prove effects of Drugs on Hum by Anonymous Coward · · Score: 0

    Many people believe that the use of drugs whether legal or illegal have no effect on your thoughts and decisions.

    There are? A few, sure, but many? That is surprising. Eating a good or bad meal can have an effect.

    because its changing you for the worse.

    Necessarily worse may be a bit excessive. Though certainly being aware that any drugs, prescribed or not, can alter your mind and in unexpected ways is prudent, I think you may be going a tad too far.

    I would say it is merely a risk. But such is life. You could suffer from reading the wrong books or associating with the wrong people just as easily.

  9. Re:Study could also prove effects of Drugs on Huma by Immerman · · Score: 4, Insightful

    Seriously? Perhaps you meant lingering *long term* effects? I mean the whole point of taking Ritalin, caffeine, marijuana, alcohol, or any other mind-altering substance is to alter your thoughts and decisions. Though of course your brain is a self-reinforcing system, and as such anything that alters it's patterns short-term will tend to cause lingering long-term effects, especially with chronic usage.

    But what makes you so sure those changes will be for the worse? It's not like we're some sort of divine beings created in an initially perfect form - we're animals with extensive symbolic reasoning systems bolted on at the last minute. Our basic natures are as brutish and shortsighted as any other animal.

    --
    --- Most topics have many sides worth arguing, allow me to take one opposite you.
  10. Paging David Suzuki by pipingguy · · Score: 1

    Where is he when you need him?

  11. The Harvard law of Animal Behavior by wherrera · · Score: 1

    Harvard law of animal behavior:

    When stimulations are repeatedly applied under precisely controlled conditions the animal reacts as it damn well pleases

    See here:

    http://en.academic.ru/dic.nsf/...

  12. Re:Study could also prove effects of Drugs on Huma by Anonymous Coward · · Score: 0

    That is a VERY fucked up comment from someone who obviously doesn't know what the fuck they are talking about. Zippy, you need to get out more my friend. I will start with your first sentence.
        >>Many people believe that the use of drugs whether legal or illegal have no effect on your thoughts and decisions
      I guarantee that ALL of the people who use drugs are well aware that the drugs change their thought process. In fact they usually have a really good laugh at someone like yourself that professes to have knowledge on a subject that they have zero experience with.

    Then you say:
    >>Most often those changes are negative in promotion of a health and well being but that is not to say that small numbers of people can't be helped by products like anti psychotics..>>>... or smoke some weed because you just don't want to give a ##### for a while.. because its changing you for the worse.

    This is so full of shit, I don't know where to start. MANY people could be helped by the nature of smoking weed. It cures physical problems such as epilepsy in almost everyone that has ever tried it as therapy including small children. (do a search). It cures depression. It makes ones awareness of their environment much more accute. I will admit that it reduces math skills for a couple of hours after smoking, but this is only temporary. As someone who has been helped immensly by weed while working a high-productivity, well-paid engineering job, I would ask that you quit talking about things that you know nothing about.

  13. Re:Study could also prove effects of Drugs on Huma by Oligonicella · · Score: 1

    Perceptions do not alter reality, otherwise a person hallucinating would affect the reality of others. And if you fall back onto the argument that the others are seeing the person hallucinate, you're stretching the meaning of your query into nonsense.

  14. Boys from Brazil by dtynan · · Score: 1

    Probably just the first stage of some mad scientist's research after watching the Boys from Brazil. http://en.wikipedia.org/wiki/T...

  15. I thinks by Anonymous Coward · · Score: 0

    I maintain that we are programmed more than this study could even conclude.

    Many sets of identical twins are strikingly similar in behavior but others have real differences in some aspects of their personality.

    Well just as they don't have identical fingerprints they don't have identical physical folds in their brains. So there is a bit of randomness to how we each turn out.

    And there are cases of identical twins where one is straight and one is gay. Likely attributable to different timing and/or amount of hormones that each received while in the womb.

    We are all programmed to be who we are. I don't see environment as a big influence ultimately (And I would attribute some environmental influences such as the choice to abuse drugs as a genetically influenced inevitablility).

    1. Re:I thinks by Anonymous Coward · · Score: 0

      Sounds like you think that you are genetically better than someone who abuses drugs?

      Do you want to say that you are a fucking nazi trying to promote eugenics?

      > And there are cases of identical twins where one is straight and one is gay. Likely attributable to different timing and/or amount of hormones that each received while in the womb.

      Your environment didn't tell you the so much needed lessons to be able to tolerate other views.

    2. Re:I thinks by king+neckbeard · · Score: 1

      Have you considered the possibility that who someone is programmed to be and the environment may be incompatible to at least some degree? Drug abuse is quite often a coping mechanism.

      --
      This is my signature. There are many like it, but this one is mine.
  16. Re:Study could also prove effects of Drugs on Huma by Hognoxious · · Score: 1

    Are we lost in the mix or are we a non-sequitur?

    I'm pretty sure that I'm not an it does not follow.

    --
    Confucius say, "Find worm in apple - bad. Find half a worm - worse."
  17. Re:Study could also prove effects of Drugs on Huma by Guy+From+V · · Score: 1

    Exactly.

  18. Re:Study could also prove effects of Drugs on Huma by sjames · · Score: 1

    Changing you, certainly. But I see no argument for why it would necessarily be for the worse in all cases.

    Also keep in mind the other things that may be changing your thinking for the worse, such as watching the news, looking at advertising, worrying about the bills, slavish adherence to a work schedule that offers little time off and subtly penalizes actually using even the little that is offered, etc.

  19. Re:Study could also prove effects of Drugs on Huma by sjames · · Score: 1

    But perceptions DO alter reality, just not that overtly. We tend to see what we expect to see and our actions based on what we see affect the state of the world and what other people see.

    Consider how the perception that only an R or a D can win the election keeps people voting for an R or a D making sure that only Rs and Ds win the elections.

  20. Random Choices by Anonymous Coward · · Score: 0

    Individuality is a random number generator. The time of conscious, strong AI is one program module nearer.

  21. Re:Study could also prove effects of Drugs on Huma by king+neckbeard · · Score: 1

    Basically everything does have an effect on you, but defining it as better or worse is not anywhere near as clear as you try to make it. We barely have any kind of a grasp on mental health. Oddly enough, we seem to be stuck on the idea that anything that makes us happy is bad for us, despite happiness being clearly important to our mental well being.

    --
    This is my signature. There are many like it, but this one is mine.
  22. i'm retarded!!! thanks god :D by Anonymous Coward · · Score: 0

    i'm retarded!!! thanks god :D

  23. Fruit flies by Intrepid+imaginaut · · Score: 1

    Please don't attempt to extrapolate human behaviour from the actions of tiny, tiny insects. That is all.

  24. We Are All Individuals! by Anonymous Coward · · Score: 0

    I'm not!

    1. Re:We Are All Individuals! by Anonymous Coward · · Score: 0

      Hmm ... so, your individuality is via not being an individual?

  25. M_RX _R R_ND Pat, I'd like to buy a vowel. by Anonymous Coward · · Score: 0

    The problem is that when one embraces empiricism (reality defined as a closed system), he locks himself into a false choice.