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New Test Could Reveal Every Virus That's Ever Infected You

sciencehabit writes: A new blood test can find almost every virus you ever caught—in a single drop of blood. Called VirScan, the test surveys the antibodies present in the bloodstream to reveal a history of the viruses you've been infected with throughout your life. Besides diagnosing current illnesses, the new test could be an important tool in developing vaccines and studying links between viruses and chronic disease.

38 of 74 comments (clear)

  1. Great tool for insurance companies, too by Anonymous Coward · · Score: 2, Interesting

    Insurance companies could use this to determine the pattern of risk in your behavior throughout your life. Someone with antibodies for a bunch of diseases related to risky behavior could be charged a higher premium to represent that tendency for greater risk-taking.

    For example, someone with antibodies for 50 different flu strains is clearly taking more risk than someone who has only, say, 10. Maybe they don't wash their hands well enough, or maybe they expose themselves to sick people more. Either way, they are riskier people and should pay more.

    1. Re:Great tool for insurance companies, too by alzoron · · Score: 2

      The flu isn't really a great example for "risky behavior." I would be surprised if I've been exposed to less than 50 strains of the flu virus and I go 3-5 years between being sick with the flu or similar on average. The flu is mostly just a symptom of a life-style that involves being around other people.

    2. Re:Great tool for insurance companies, too by camperdave · · Score: 1, Offtopic

      For example, someone with antibodies for 50 different flu strains is clearly taking more risk than someone who has only, say, 10.

      Yeah... Or maybe they've had 50 different flu shots.

      --
      When our name is on the back of your car, we're behind you all the way!
    3. Re:Great tool for insurance companies, too by rmdingler · · Score: 3, Interesting

      The flu isn't really a great example for "risky behavior." I would be surprised if I've been exposed to less than 50 strains of the flu virus and I go 3-5 years between being sick with the flu or similar on average. The flu is mostly just a symptom of a life-style that involves being around other people.

      A mega-flora of flu antibodies might actually be good for an applicant for insurance, as it generally represents greater future immunity to evolving flu strains.

      Positives for hepatitis, HIV, etc. would definitely encourage the insurance company to attempt to opt you out.

      wink wink If your maths are correct, I would be interested in getting your Doc's name and a reference.

      --
      Happiness in intelligent people is the rarest thing I know.

      Ernest Hemingway

    4. Re:Great tool for insurance companies, too by Anonymous Coward · · Score: 1

      Insurance companies could use this to determine the pattern of risk in your behavior throughout your life. Someone with antibodies for a bunch of diseases related to risky behavior could be charged a higher premium to represent that tendency for greater risk-taking.

      Well, I guess now the ACA is going to do some good for everybody then, since they can't do that.

    5. Re:Great tool for insurance companies, too by gatkinso · · Score: 1

      >> For example, someone with antibodies for 50 different flu strains is clearly taking more risk than someone who has only, say, 10

      Explain the line of reasoning behind this.

      --
      I am very small, utmostly microscopic.
    6. Re:Great tool for insurance companies, too by Paradise+Pete · · Score: 2

      Nor is being 23 and male.

      Statistically, yes it is. 23 year old males are total idiots when it comes to their safety.

    7. Re:Great tool for insurance companies, too by DarkOx · · Score: 3

      If you show positive for HIV the insurance company already has a problem. I think it would work more like this. You show positive for having once had the clap or have HPV. Now you are marked as someone who has/had risky sex, ie outside a monogmous relationship where your partners health status is known or unprotected sex with anyone else. Your risk of contracting something expensive to treat like herpes or HIV went from very low to reasonably possible. Now the insurance company has a good reason to get you off their books.

      That is probably the most likely example I can think of.

      --
      Repeal the 17th Amendment TODAY! Also Please Read http://www.gnu.org/philosophy/right-to-read.html
    8. Re:Great tool for insurance companies, too by DarkOx · · Score: 2

      Actually being in ones early 20s and male is highly correlated with auto accidents that is why the actuaries tell them to do that. Just like being in ones early 20s and female is highly correlated with requiring more frequent and more expensive medical care for a number of conditions including pregnancy.

      For some reason though charging more for one is a prudent insurance practice and discrimination blocked by the ACA for another.

      --
      Repeal the 17th Amendment TODAY! Also Please Read http://www.gnu.org/philosophy/right-to-read.html
    9. Re:Great tool for insurance companies, too by Delwin · · Score: 1

      Except for the part where it only detects families - so norovirus would come up only once no matter how many variants of the flu you have.

    10. Re:Great tool for insurance companies, too by mr_mischief · · Score: 1

      There are generally three or four *main* strains going around each year, and a bunch of other less common ones. That's why flu shots are way less effective than would be hoped. This year the US is saying about 19% effective because they picked the strains they thought would be the most common threats.

    11. Re: Great tool for insurance companies, too by Type44Q · · Score: 2

      And... neither of those are viruses... but thanks for playing!

    12. Re:Great tool for insurance companies, too by Trax3001BBS · · Score: 1

      There are generally three or four *main* strains going around each year, and a bunch of other less common ones. That's why flu shots are way less effective than would be hoped. This year the US is saying about 19% effective because they picked the strains they thought would be the most common threats.

      And why I've always refused a flu shot or other frivolous concoctions. When Regan made the older folks take the shots he weeded out the weak ones; I've read many articles where a "harmless" vaccine has caused unbelievable problems for some. I'm fairly healthy less my post below so don't feel it worth the risk.

      Living in Washington State I won't even get my dog a rabies shot as the chances are so rare he would become effected, and so great it could take him out. This statement even agreed to by a veterinarian, mentioning the lack of rabies in this area and carried only by bats which in 40 years here seeing only one, and it stuck inside a tree limb that was cut down.

    13. Re:Great tool for insurance companies, too by Trax3001BBS · · Score: 1

      Insurance companies could use this to determine the pattern of risk in your behavior throughout your life. Someone with antibodies for a bunch of diseases related to risky behavior could be charged a higher premium to represent that tendency for greater risk-taking.

      For example, someone with antibodies for 50 different flu strains is clearly taking more risk than someone who has only, say, 10. Maybe they don't wash their hands well enough, or maybe they expose themselves to sick people more. Either way, they are riskier people and should pay more.

      That concern is over, it was a reality awhile back but now days, bragging where you are on a social site can have a cruise missile sent your way. The Internet is all about collecting info, cause it can be sold to Flurry.com who in turn sales it to others for personalized ads (lots of money involved), if you've ever posted of a medical problem you've had, it's public domain. Your private medical records available on demand by just about anybody. Read the next privacy policy you sign over a medical condition, which you authorize anybody having a medical interest in you to request and be sent your records.

      I don't think insurance companies are as big of a concern as they once were when it comes to info on you (more so as your no longer able to keep pertinent info from them). Most of the time just getting the correct key words into Google will do the trick. Why I was always from Uganda and a 35 year old male - Yet don't use a proxie and Google knows all of my accounts, the list to choose from is getter rather troublesome. - I could easily rant over this subject, /. was all about warnings of such activity, now it's old hat.

    14. Re:Great tool for insurance companies, too by Trax3001BBS · · Score: 1

      Positives for hepatitis can also mean you have had the hepatitis vaccine. They can currently test for hepatitis antibodies to check whether you need a booster....

      Sorry, that's not true. I've posted below over my dealings with hepatitis, as far as I'm aware (been out of the medical field for a long time) gamma globulin is what one is given as quickly as possible if hepatitis is a possibility -preventing one from acquiring it; a vaccine I've never used. Once one has hepatitis they have it, there is no cure (it has to leave on it's own unless type C), again a long time since I've been in the medical field (Pharmacist).

      A copy and paste:
      "I've always claimed I had hepatitis, twice in fact the first time when I was 5 years old, yet no clue which "strain", last year I had blood work done to test for hepatitis, it came back I had had A and B, not a carrier and I haven't had hepatitis in quite sometime, as told by the antibodies." In this case the antibodies just showed I had had hepatitis at one time, and only a marker. Will admit that the antibodies were so few that the test barely picked them up, being in fact almost non-existent.

      And in all fairness wikipedia does mention a booster vaccine for type B hepatitis.

  2. Metadata only? by mschaffer · · Score: 5, Funny

    Next they will be saying that the test only looks at the Virus' metadata. They will only be logging the numbers of those who infected you, but not look at the actual antibodies.

    1. Re:Metadata only? by srussia · · Score: 1

      Next they will be saying that the test only looks at the Virus' metadata. They will only be logging the numbers of those who infected you, but not look at the actual antibodies.

      Cute, but antibodies are metadata .

      --
      Set your phasers on "funky"!
  3. Great application by Anonymous Coward · · Score: 1

    A great application would be to find people who have developed antibodies for deadly diseases that we as yet don't have a cure for.

    1. Re:Great application by Z00L00K · · Score: 2

      Antibodies do exist for viruses that the body has had to take down, but what if the body is already resilient against a virus because it lacks the "handle" the virus needs?

      --
      If builders built buildings the way programmers wrote programs, then the first woodpecker would destroy civilization.
    2. Re:Great application by Gilgaron · · Score: 3, Interesting

      Sure, if you were immune do to mutated cell receptors you'd be unlikely to have gotten enough virus to trigger an antibody response. Likewise this would probably only look back 10 years or so, as last I'd heard that was how long memory B cells are thought to live.

    3. Re:Great application by Gilgaron · · Score: 1

      The AC who responded to you makes a good point I hadn't considered in my initial post. While 10 years is about as long as B cells are thought to live, detectable titers could persist for longer from whatever percentage live longer than that. Booster shots make sure you have a sufficient number of said B cells to make antibodies quickly enough to remain healthy, and the annual pet vaccines are often akin to flu shots where they chase the current strains.

  4. Tainted mission statements. by geekmux · · Score: 4, Insightful

    The sad part about reading about yet another mission to capture Big Data is not how it can be used for us, but how it can be used against us.

    I hate having to think that way, and yet I'm forced to now. Every time.

    I also struggle who to blame more. A society that demands everything for free, or the corporations that gladly subsidize those demands by selling your online soul in exchange.

    1. Re:Tainted mission statements. by Anonymous Coward · · Score: 2, Insightful

      The sad part about reading about yet another mission to capture Big Data is not how it can be used for us, but how it can be used against us.

      I hate having to think that way, and yet I'm forced to now. Every time.

      You're in good company. Nearly every man who helped frame the US constitution was forced to think that way to prevent future abuses of power.

  5. Don't vote GOP if you don't like it then! by Joe_Dragon · · Score: 1

    Don't vote GOP if you don't like it then! Even more so with the end of job based health insurance.

    As under the old system the only plans that will cover you will be some type of Medicaid plan (if you qualify) and Medicare (if you qualify) In the past some people where on Disability just for the healthcare and had to cut hours on the job as mini wage went up.

    Other then there the ER that will cover some stuff and try to bill you for it. All at a higher cost of Medicare for all.

    Bearing that the jail / prison system will pick up the slack at a much higher cost the then ER.

  6. I would LOVE to see it ran against me! by wwphx · · Score: 2, Interesting

    I have a condition called hypogammaglobulinemia. My body doesn't produce immuneglobin. I do weekly infusions of immuneglobin and have done so for six years now. The med is made from the donations of 10,000 people.

    What virus have I NOT had under this test?

    --
    When you sympathize with stupidity, you start thinking like an idiot.
    1. Re:I would LOVE to see it ran against me! by del_diablo · · Score: 1

      Black Death?

  7. Please tell me. . . by Idou · · Score: 4, Insightful

    that I can get this test so that next time I get sick they can check the difference and have an explicit idea of what I have. . .

    Now, every time I go to the doctor, they are like "we will put you on these antibiotics and if you don't get better, you have a virus." It feels like the freaking middle ages. . .

    --
    Sdelat' Ameriku velikoy Snova!
    1. Re:Please tell me. . . by Dripdry · · Score: 1

      I apologize for being blunt, but:
      If the doc is giving you antibiotics for every little thing, he's an idiot (or probably just giving you placebo).

      --
      -
    2. Re:Please tell me. . . by Idou · · Score: 1

      Not sure if it is my writing style or just the average /.er's reading comprehension but "every time I go to the doctor" does not indicate the actual frequency of doctor visits nor the severity of a given visit. It could apply to an average visit of once every 4 years due to symptoms serious enough that official advice is "go see a doctor if you have symptoms like this" (which describes my case) .

      Yes, since the tools to economically diagnose viral vs bacterial infections does not exist, doctors do tend to push antibiotics like complete idiots, just incase you have bacterial infection (that is kind of the whole point of my earlier post. . .).

      --
      Sdelat' Ameriku velikoy Snova!
  8. Works only if ... by 140Mandak262Jamuna · · Score: 2

    Your body is still producing those anti bodies, and they have cataloged that substance in the data base and weeded out anti-bodies produced by auto-immune diseases, to reduce false positives. But still it is a major advancement.

    --
    sed -e 's/Chuck Norris/Rajnikant/g' joke > fact
  9. Really? by Anonymous Coward · · Score: 1

    Even after I format my disk?

  10. Ah yes, now what viruses are associated with cance by aurizon · · Score: 2

    I know some viruses insert into the genome at random places. Some of the places are close to known oncogenes, and may enhance the risk of expressing those oncogenes.
    A virus known to do this may well be otherwise harmless, but if we can identify it, we may be able to vaccinate children against it, thus reducing the later risk of cancer from that cause. There might be dozens of them and we might be able to reduce cancer over-all this way

  11. One Problem with the test is interpretation by Anonymous Coward · · Score: 1

    I am an MD, and I get misinterpretations of this test all the time. Some of my patients with Chemical Sensitivity and/or Chronic Fatigue were poisoned and also have fear/stress/anxiety issues. Both poisoning and fear/stress/anxiety can increase all antibodies even the viral antibodies with no prior viral infections.

    Poison such as pesticide can act as an immune stimulant to provoke the body into producing antibodies to everything. This immune stimulant effect is known as an adjuvant. Adjuvants in immunology provoke and potentiate an immune response. But Adjuvants are non-specific. Whatever is presented to the body, the body ramps up more production of antibodies with an adjuvant. Present a virus to the body with an adjuvant and the body produces more antibodies to the virus. This is why adjuvants are always used in vaccines.

    The problem is that if you bump your elbow while taking an adjuvant, elbow cells are released into the body. The body begins to produce anti-elbow antibodies. I recall there was one vaccine given to dogs that produced a Lupus in the dogs.

    Fear/stress/anxiety releases extra histamine and interleukin-6 into the body potentiating the immune response as well.

    The end result is that either poisoning or fear/stress/anxiety can produce anti-virus antibodies WITHOUT the actual infection.

  12. Antibodies do not last forever. by Khyber · · Score: 1

    Saying this could tell you every virus you had in your life is nonsense. Antibodies do not last forever in the body. If they did, we wouldn't require BOOSTER SHOTS.

    --
    Still waiting on Serviscope_minor to wake up to fucking reality and realize that Jessica Price isn't going to fuck him.
  13. Just viruses? by quenda · · Score: 1

    Don't we have antibodies for bacteria and other pathogens also? Are they somehow less interesting?

  14. Measles by n-carro2 · · Score: 1

    I heard this article in the CBC. http://www.cbc.ca/radio/quirks... Here is a quote: "They found that in animal models, measles provokes a kind of "immune amnesia", in which the immune system forgets how to fight infections it's previously encountered. Further epidemiological work suggested that this amnesia can last more than two years, causing roughly 50% more deaths than would have happened otherwise." This would affect the validity of this test and makes me question if this is the only disease that has this affect.

  15. Whoa, I think this is not true... by Dripdry · · Score: 1

    Antibodies only stay in the body to combat viruses for a certain period of time after that virus was killed, not one's whole life. That is my understanding from a Duke-trained med student.
    Are there certain viruses that show antibodies for one's entire life and ones that don't? or is the headline misleading? I am very curious.

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    -
  16. It's very close to being a reality now. by Trax3001BBS · · Score: 1

    I've always claimed I had hepatitis, twice in fact the first time when I was 5 years old, yet no clue which "strain", last year I had blood work done to test for hepatitis, it came back I had had A and B, not a carrier and I haven't had hepatitis in quite sometime, as told by the antibodies.

    A few weeks ago I proved to my self age is catching up, by dropping to the floor when my Kidneys quit working, a series of unusual events saved my life. A blood test was taken (as expected) but they could measure an enzyme and tell I how long I had been on the floor (a very long time). While kool trying to piece together what happened to me, it was claimed by those living close by I was down for less than the given time (so still a bit of work left) - Kidneys started right back up and not a problem now, but I was told I was the bluest person anyone had ever seen.

    A blood test from me was explained to my sister as I thought I was being treated in North Korea (just out of it), she couldn't believe what they were able to tell with just that one sample (apparently a lot), she was quite impressed as it was being explained to her.

    BTW if interested, I'm retired and the hospital bill less the ambulance ride there came to over $8000, my amount due is $0.00, I've got some great insurance I lucked into just by being older. (and not Obama care).

    But with just those two examples, I can see a tell all blood test in the near future.