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Studies Find Genetic Signature of Native Australians In the Americas
Applehu Akbar writes: Two new research papers claim to have found an Australo-Melanesian DNA signal in the genetic makeup of Native Americans, dating to about the time of the last glacial maximum. This may move the speculation around the Clovis people and Kennewick man to an entirely new level. Let's hope that it at least shakes loose some more funding for North American archaeology. Ars reports: "The exact process by which humanity introduced itself to the Americas has always been controversial. While there's general agreement on the most important migration—across the Bering land bridge at the end of the last ice age—there's a lot of arguing over the details. Now, two new papers clarify some of the bigger picture but also introduce a new wrinkle: there's DNA from the distant Pacific floating around in the genomes of Native Americans. And the two groups disagree about how it got there."
Scientific progress thrives in a diverse climate of research projects. Also, direct utility is in genetic disposition to disease showing patterns in existing populations.
My understanding is not that an Austro-Melanesian population contributed to American Indian DNA, but rather that some progenitor population in Asia bequeathed their DNA to both groups. This puts a somewhat different hide on the cat, underlining that the Paleo-Indians were not a homogeneous Siberian population, but rather themselves were descended from a patchwork of groups in Asia who entered and likely interbred for centuries in Beringia.
The world's burning. Moped Jesus spotted on I50. Details at 11.
That you're imagination is so limited should not reflect on science's need for basic research. Unless you have a crystal ball that accurately reports what basic research taking place now is going to blossom into value further down the road, all you have is a pretty goddamned mindless anti-intellectual rant.
The world's burning. Moped Jesus spotted on I50. Details at 11.
Also, direct utility is in genetic disposition to disease showing patterns in existing populations.
Yes, but massive understatement.
It's now possible to get your entire genome sequenced for only $1,000 - by sending (e.g. FedEx) a small tube of saliva to a sequencing facility (e.g. Macrogen in Korea). In another few years, millions of people are going to have had their genomes sequenced. And people are going to be using their genome sequences to understand everything from rare genetic disorders (i.e. inherited birth defects) to the most effective treatment for their cancer.
In most cases, you're going to want to compare your own genome to a reference genome. And this comparison will be more informative if you can choose a reference that matches your whatever ancestral population(s) you are descended from.
And you're also going to want to know about pathogenic variants that may cause disease for you or your descendants. So, let's say your have an A at position 12,143,021 on chromosome 15 where most people have a T. In fact, let's say that 10 million genomes have been sequenced at that point and only 100 people share that variant. Well, maybe all those people are a little bit sick with the same symptoms that you have. But suppose you know more about the populations. Suppose you know that all those 100 people are members of a larger population of 10 million people - and that this variant is likely to occur in most of the 10 million people in that population. In that case, you can be pretty sure that the variant is benign - that it's not the cause of your symptoms.
Clinical genome sequencing is going to be one of the biggest revolutions in the history of medicine - right up there with aseptic surgery and antibiotics. And understanding how human genetic variation is distributed across populations is going to be key to interpreting these genomes.
More likely, there was a lot more going on during the last ice age period than is currently known because the evidence was buried by rising sea waters as well as inland glacial melt flooding.
Chaos - everything, everywhere, everywhen