Eye Drops Could Dissolve Cataracts

An anonymous reader writes: As Slashdot readers age, more and more will be facing surgery for cataracts. The lack of cataract surgery in much of the world is a major cause of blindness. Researchers at University of California San Diego have identified lanosterol as a key molecule in the prevention of cataract formation that points to a novel strategy for cataract prevention and non-surgical treatment. The abstract is freely available from Nature. If you have cataracts, you might want to purchase a full reprint while you can still read it.

Comments

Secondary Cataracts

[Anonymous Coward]

Pfft, what about those of us with secondary cataracts? I'd like to see an eye drop dissolve that. Fools! Why even waste their time on this trash?

Effective cataract eye drops are already available

[Eukariote]

N-acetyl carnosine drops have been used with good success for a while. Bought them for my grandmother in law. Over the course of a couple of years it halted and mostly reversed her developing cataracts. Can get them from multiple sources.

Here is a link to a paper describing some of the early research.

Re:Effective cataract eye drops are already availa

[Ungrounded Lightning]

N-acetyl carnosine drops have been used with good success for a while. Bought them for my grandmother in law. Over the course of a couple of years it halted and mostly reversed her developing cataracts. Can get them from multiple sources.

Good information - especially while we're waiting for this stuff to become available.

I note, though, that:
  - This newly-identified material substantially clears cataracts in six days while N-acetyl carnosine takes four months for significant improvement to show.
  - This newly-identintified material appears to be what the eye normally uses in a specific mechanism to prevent/repair cataracts, while N-acetyl carnosine appears to have more generic antioxidant and chelation properties. (It's a modification of carnosine to a form which can penetrate the tissues of the eye and is converted back to carnosine within them. Carnosine is great for retarding several ageing mechanisms but it looks more like a generic helper than a specific repair-mechanism component or trigger for cataracts.)
  - The discovery of this new stuff occurred by identifying what was missing in people with a genetic early-cataract problem. If this is necessary for cataract prevention/repair and its production declines (but doesn't fully stop) with age, N-acetyl carnosine might not work for people who don't make it at all.

So though N-acetyl carnosine looks good, this looks great and specific. (And I don't see any reason to stop the former even if taking the latter. Unless some specific interaction issue shows up I'd expect them to work well together.)