Eye Drops Could Dissolve Cataracts

An anonymous reader writes: As Slashdot readers age, more and more will be facing surgery for cataracts. The lack of cataract surgery in much of the world is a major cause of blindness. Researchers at University of California San Diego have identified lanosterol as a key molecule in the prevention of cataract formation that points to a novel strategy for cataract prevention and non-surgical treatment. The abstract is freely available from Nature. If you have cataracts, you might want to purchase a full reprint while you can still read it.

Comments

Effective cataract eye drops are already available

[Eukariote]

N-acetyl carnosine drops have been used with good success for a while. Bought them for my grandmother in law. Over the course of a couple of years it halted and mostly reversed her developing cataracts. Can get them from multiple sources.

Here is a link to a paper describing some of the early research.

Re:Effective cataract eye drops are already availa

[Ungrounded Lightning]

N-acetyl carnosine drops have been used with good success for a while. Bought them for my grandmother in law. Over the course of a couple of years it halted and mostly reversed her developing cataracts. Can get them from multiple sources.

Good information - especially while we're waiting for this stuff to become available.

I note, though, that:
  - This newly-identified material substantially clears cataracts in six days while N-acetyl carnosine takes four months for significant improvement to show.
  - This newly-identintified material appears to be what the eye normally uses in a specific mechanism to prevent/repair cataracts, while N-acetyl carnosine appears to have more generic antioxidant and chelation properties. (It's a modification of carnosine to a form which can penetrate the tissues of the eye and is converted back to carnosine within them. Carnosine is great for retarding several ageing mechanisms but it looks more like a generic helper than a specific repair-mechanism component or trigger for cataracts.)
  - The discovery of this new stuff occurred by identifying what was missing in people with a genetic early-cataract problem. If this is necessary for cataract prevention/repair and its production declines (but doesn't fully stop) with age, N-acetyl carnosine might not work for people who don't make it at all.

So though N-acetyl carnosine looks good, this looks great and specific. (And I don't see any reason to stop the former even if taking the latter. Unless some specific interaction issue shows up I'd expect them to work well together.)