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Another Neurodegenerative Disease Linked To a Prion

MTorrice writes: A new study concludes that a brain protein causes the rare, Parkinson's-like disease called multiple systems atrophy (MSA) by acting like a prion, the misbehaving type of protein infamously linked to mad cow disease. The researchers say the results are the most definitive demonstration to date that proteins involved in many neurodegenerative disorders, such as Alzheimer's and Parkinson's, exhibit prion-like behavior: They can misfold into shapes that then coax others to do the same, leading to protein aggregation that forms neurotoxic clumps. If these other diseases are caused by prion-like proteins, then scientists could develop treatments that slow or stop disease progression by designing molecules that block prion propagation.

2 of 53 comments (clear)

  1. Re:Folding@Home by PopeRatzo · · Score: 2, Insightful

    Zero. It was 100% funded by big bad Pharma that you guys all claim to hate.

    Wrong. It was funded by the customers of big bad Pharma.

    Remember, all corporate research is ultimately funded by customers. Before you go giving them some humanitarian award. don't forget it's always the customers that pay the bill.

    --
    You are welcome on my lawn.
  2. Stanley Pruisner by SecurityGuy · · Score: 4, Insightful

    It's interesting for me to see this guy's name come up. I remember reading a fairly derogatory article about him in Scientific American in the 80s, all but calling him a fraud. Sometimes the "fraud" is proven right. Worth remembering.