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Another Neurodegenerative Disease Linked To a Prion

MTorrice writes: A new study concludes that a brain protein causes the rare, Parkinson's-like disease called multiple systems atrophy (MSA) by acting like a prion, the misbehaving type of protein infamously linked to mad cow disease. The researchers say the results are the most definitive demonstration to date that proteins involved in many neurodegenerative disorders, such as Alzheimer's and Parkinson's, exhibit prion-like behavior: They can misfold into shapes that then coax others to do the same, leading to protein aggregation that forms neurotoxic clumps. If these other diseases are caused by prion-like proteins, then scientists could develop treatments that slow or stop disease progression by designing molecules that block prion propagation.

2 of 53 comments (clear)

  1. Too Tired To Read by Anonymous Coward · · Score: 4, Funny

    For a moment I thought it read "Another Neurodegenerative Disease Linked to Porn". I was very concerned during that moment.

  2. Stanley Pruisner by SecurityGuy · · Score: 4, Insightful

    It's interesting for me to see this guy's name come up. I remember reading a fairly derogatory article about him in Scientific American in the 80s, all but calling him a fraud. Sometimes the "fraud" is proven right. Worth remembering.