U.K. Researcher Receives Permission To Edit Genes In Human Embryos (sciencemag.org)
sciencehabit writes: Developmental biologist Kathy Niakan has received permission from U.K. authorities to modify human embryos using the CRISPR/Cas9 gene-editing technology. Niakan, who works at the Francis Crick Institute in London, applied for permission to use the technique in studies to better understand the role of key genes during the first few days of human embryo development.
The Human Fertilisation and Embryology Authority (HFEA), which grants licenses for work with human embryos, sperm, and eggs in the United Kingdom, approved Niakan's application at a meeting of HFEA's license committee on 14 January. The minutes of that meeting state that, '[o]n balance, the proposed use of CRISPR/Cas9 was considered by the Committee to offer better potential for success, and was a justified technical approach to obtaining research data about gene function from the embryos used.'
The Human Fertilisation and Embryology Authority (HFEA), which grants licenses for work with human embryos, sperm, and eggs in the United Kingdom, approved Niakan's application at a meeting of HFEA's license committee on 14 January. The minutes of that meeting state that, '[o]n balance, the proposed use of CRISPR/Cas9 was considered by the Committee to offer better potential for success, and was a justified technical approach to obtaining research data about gene function from the embryos used.'
KHAAAAAAAAAAAAAAAN!
(and some filler to make sure Slashdot doesn't block this because of excessive capitalization)
& other stuff we aloofians just do not do? little miss dna cannot be wrong bit she can be wronged? yikes almighty... in our own image again no doubt?
welcome our new crispy overlords...
Aside: Anyone else think of a drawer in the refrigerator or apples when anyone mentions CRISPR?
My eyes reflect the stars and a smile lights up my face.
this clone war has!
So this is news because it was announced in the UK? Haven't other countries (like israel) been doing these experiments for awhile now?
wind gusts of 50mph+ to add to the adventure..... truth+mercy=justice... free the innocent stem cells.. no bomb us more mom us...
Welcome to the new owners of /.
congtrats, I hope the new ORG understands the true purpose of this website..
News for nerds..
I wil admit, at times I got great pleasure berrating your former collegues (DHI) for their lack of understanding and intelligence on their own subject matter, but I am now glad that chapter of our lives is over..
Now on to bigger and better things..
I am writing this because it seems this article about embryo experments seems more along the lines of "nature.com, or yahoo news" naught necessarily newz 4 nerdz.
My hope is that this is a fluke, or a misunderstanding on either side of the fence. /. is trying to portray..
But if not, pls take a moment to realize the perspective of what
Thanks
Oi Mate, is that a third arm you got down there or are you just happy to see me.
CRISPR(tm): More appendages for more people. Join the Revolution.
...how the babies feel about the Drs Frankenstein modifying their DNA?
You can't be allowed to do wrong things because others are already doing it. That's not possible.
Now, I suppose UKians can decide what they do with their own country and people.
IMHO, 'the proposed use of CRISPR/Cas9 was considered by the Committee to offer better potential for success, and was a justified technical approach to obtaining research data about gene function from the embryos used' is not enough of a justification.
But I rejoice I don't have any English relative; OTOH, aren't we all human? (despite what they're doing...)
Gimme some glow-in-the-dark embryos.
Three boobs.
"you'll wish you had three hands" and now you actually can.
chmod -R 777 /embryo/human/DNA
or...
Open C:\embryo\human and right-click on folder "DNA". Click on the "Security" tab and then click the "Edit..." button. In the "Permissions for DNA" window, click the "Add..." button.
Now, in the "Select Users, Computers, Service Accounts, or Groups", click in the "Enter the object names to select (examples):" text box and type, "UK\Users" then click "OK".
Assure that the checkbox "Full control" is selected in the "Permissions for Users" area.
Finally click "OK".
Please call support if you have any problems or further questions.
...of civilisation:
The term ‘eugenics’ was first used by Francis Galton in 1883 when examining the “comparative worth” of different races, to describe the improvement of man through “better breeding“. Other terms that evolved included:
Dysgenic: Elements believed to increase the occurrence of undesirable genes.
Negative eugenics: Those classified as the ‘genetically unfit.’
V.S.
Eugenic: Elements believed to increase the occurrence of desirable genes.
Positive eugenics: Those classified as the ‘genetically fit’.
Eugenic campaigns began in earnest in several nations including the UK, USA and Germany, with the establishment of the British Eugenics Education Society (1907), American Eugenics Society (1923) and the Society for Racial Hygiene (1905) respectively.
Eugenicists came to believe that the goal of ‘better breeding’ could be achieved through the sterilisation of dysgenic individuals and the promotion of breeding amongst the genetically fit.
Involuntary sterilisation was never passed as law in the UK, despite the campaigning of British eugenicists. In the USA and Germany however, the practice became widespread. Whilst less publicised than its German equivalent, the eugenics movement in the USA, resulted in the forced sterilisation of 65,000 individuals up to the program’s eventual end in the early 1970s.
In Germany however, eugenics found its ideal social and political environment in which it could thrive.
With the nation locked in a post- World War 1 economic crisis, eugenicists held the opinion that medical care had interfered with the laws of nature by keeping the weak alive and that “defectives” were reproducing faster than healthy individuals.
Amongst the so-called ‘defectives’ were the hereditary blind and deaf, those with “physical deformities” and the congenitally “feebleminded” (those with learning difficulties).
Fürsorge (care of the individual) was to be condemned whereas Vorsorge (preventative care for the good of the nation) was to become medicine’s priority; with the role of the physician as a “cultivator of the genes” and “biological soldier.”
The resulting eugenic campaign between 1933 included the forced sterilisation of up to 375,000 people between 1933-39; and ultimately the killing of hundreds of thousands of those deemed to be “life unworthy of life”. Doctors involved in the campaign claimed that the Hippocratic oath was a “vestige of ancient times” and that such killing complied with medical ethics since these people were mere “empty shells of human beings” and “effectively already dead.”
These actions by Nazi physicians is well summarised by Christian Pross:
"The search for truth in medicine turned into destruction when medicine abandoned the Hippocratic ‘nil nocere‘and this was done for science’s own “superior” aims."
Shall we even go there with the Aryan breeding programme and Lebensborn, which continues in BRITAIN to this day?
Political debates have me rolling my eyes so much I think I got optical whiplash. I should sue. - Foamy The Squirrel
In soviet russia genes edit you!!?
20 years or so from now, people not genetically "optimized" for a certain sport won't make it into the top ranks.
I don't mind, though, since everyone else can still enjoy sports for the fun of it. It's not like people stopped playing chess just because a PC is better than a grandmaster in that discipline...
i guess your parents could have requested you be genetically engineered to grow a pair and not be frightened of registering yourself on /.
"The hands that help are better far than lips that pray." - Robert Ingersoll (1833-1899)
Have you watched any of the GOP presidential debates?
You are welcome on my lawn.
https://www.youtube.com/watch?v=VB65Hrdq_Sc
Nope, there will be two leagues and people will be registered just like you register your dogs pedigree today, along with the genetic background - i.e. you parents and grandparents, etc. to prove you are a pure bred and not a optimized breed. And the Opti's will be registered also, so they can breed selectively.
Didn't we hear the same thing in the mid-90's, before the biotech industry collapsed the first time. (It's crashing now ... again ... )
Why, yes, it is 20 years later. Still no designer babies.
Required reading for internet skeptics
Why do you think there aren't designer babies? LOL. Look into these technologies: IVF (In-vitro fertilization) and PGD (Preimplantation genetic diagnosis). So basically the way it works is: you grow a few embryos until they are a few cells large. Take one of the cells, sequence the DNA. Do this for a few different embryos. Chose the embryo with the DNA you like the best. (No, this is really "chose the embryo that doesn't have genetic diseases", but can quickly become "I want a male/female child" (this is already a thing), or "I want a child with blue eyes" (this is not yet a thing, but because of ethical reasons, NOT technological ones, we already have the phenotype->genotype mapping for blue eyes.))
So basically - designer babies is ALREADY a thing, scientists are just too chicken (read as: ethical) to use it for anything like "I want only blue eyed blond haired kids".
> Niakan, who works at the Francis Crick Institute in London, applied for permission to use the technique in studies to better understand the role of key genes during the first few days of human embryo development.
Yeah like the Nazi scientists who froze jews to death to better understand what happens when you freeze people to death. Zig Heil, HFEA, das furher is proudst ja ja ja!
Imagine if Galileo had to 'ask permission' from the church to be allowed to use a telescope to look at the sky and 'ask for permission' to take observations that could propose heliocentric theory. We would still think the earth is the center of the universe, absurd.
Real scientists don't ask for permission... they just methodically investigate.
Also, real scientists aren't afraid of being punished by authorities, because their results disagree with popular notions.
We're also terrible at it. With our extremely limited understanding of genetic disorders you could try to get all "Grade A athletic and bright kids" and end up with massively disabled offspring instead. It's like trying to pick out a song you like by looking at the sheet music, and you only know what one musical symbol means.
"Now, would you like your child to have feet, or pods?"
vi or emacs?
Unbelievable. Is even one of you capable of imagining the suffering of another being?
Nazis - forgot to read about animal husbandry... basically just ignorant savages.
Slavery - encouraged the breeding of the large, the strong, and the compliant...
Fiction: the Ira Howard Foundation, Heinlien... bribery used to encourage gene reinforcement...
( I think he read a book on animal husbandry )
DNA Manipulation - probably premature since the science is still in its infancy.
Lotsa mistakes will happen...
But go ahead, get all excited, jimmies rustled, biblically aroused, ethically offended, and politically demostrative about it...
Then as the poodle, dachsund, and greyhounds how they feel about breeding...
And read up on statistics of genetic defects due to inbreeding in various human groups...
I, personally, think that if the scientists can locate the asshole ( not gender-specific ) gene and figure out how to turn it off...