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Study: Mice Gain Weight In Cold Temperatures Due To Gut Changes (economist.com)

Beeftopia writes with the results of a study described in The Economist: Mice were separated into two groups, one temperature maintained at 6C, the other at 22C. Researchers expected the cold mice to lose weight as they burned stored fat to stay warm. And for the first few days they did. But after five to ten days, in spite of their rations not increasing, the cold mice begain to put on weight. When scientists examined the gut microbiome of the previously identical mice, they found they were radically different. Additionally, the intestine had grown villi 50% larger than those of the warm temperature mice. Finally, after transplanting the gut microflora into a new batch of aseptic mice kept at warm temperatures, those mice showed the increased insulin sensitivity, cold tolerance, and villi length of the cold mice.

2 of 132 comments (clear)

  1. Re:Gained weight despite unchanged diet by Beeftopia · · Score: 3, Insightful

    It's also paradoxical. Cold weather should speed up the metabolism, and thus, on the same diet, the organism should lose weight, not gain it. Yet the adaptation to gain fat to likely protect body temperature kicks in, generating changes in the digestive subsystem to achieve that end.

  2. Re:Gained weight despite unchanged diet by Anonymous Coward · · Score: 4, Insightful

    What IS it about fat people where they get enraged when someone points out they're fat?

    What IS it about skinny people that they appoint themselves as self-righteous pricks by offering unsolicited, and often inappropriate, advice to fat people? A friend insisted that I run seven miles a day even though it would blow out my knees. A coworker insisted that I drink water all the time even though I drink more water than him. Another coworker insisted in front of other coworkers at a meeting that I get lap-band surgery even though we weren't talking about my weight.

    Everyone can not only see, but see exactly how fat you are as well.

    I don't have a problem with being fat. I'm on a low carb diet, work out at the gym and drink plenty of water. I'm doing what I can do without killing myself in the process. Seems like skinny people are insecure around me because I'm not insecure or ashamed of being fat. I put that nonsense behind me years ago.

    I get the same type of self righteous crap from people about my diabetes, which I have had for about 18 years, and I usually let them tell me all the shit about what I should and shouldn't eat, and how it is all my fault.. and I wait about a beat and smile and tell them that I have type 1 diabetes not the type that you get from insulin resistance and the non alcoholic fatty liver syndrome effects.

    People are dicks, unless they work not to be. It is more about them and their insecurities and inferiority complexes and confirmation biases than it is about you. Pay those idiots no mind is my advice. The lady that suggested lap-band surgery out of the blue needs to be complimented on her lack of people skills and have an HR complaint filed it sounds like. I would have just laughed and said something like "I can get on a treadmill, what can you do about just being ugly? Bag over the head much?"

    Not everyone is the same, has the same habits or conditioning or gut flora and all of it matters to one degree or another. I have a fucked up mean immune system is my problem and it is no ones fault. It just happened. This does not stop idiots who don't have a problem ascribing to their skill or moral superiority, something that has happened by chance. This is a cognitive bias on their part and nothing to do with you, let them be morons.. rest assured that people around within earshot don't think those people are smart or witty or anything but ugly bags of mostly water.

    Carry on with your exercise and build some muscle .. and someday kick their ass when they mouth off.. :)

    And most importantly, be happy!