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Prescription Meds Get Trapped In Disturbing Pee-To-Food-To-Pee Loop (arstechnica.com)

An anonymous reader quotes a report from Ars Technica: A study published Tuesday in Environmental Science and Technology is the first to validate the long-held suspicion that pharmaceuticals may get trapped in infinite pee-to-food-to-pee loops, exposing consumers to drug doses with unknown health effects. In a randomized, single-blind pilot study, researchers found that anti-convulsive epilepsy drug carbamazepine, which is released in urine, can accumulate in crops irrigated with recycled water -- treated sewage -- and end up in the urine of produce-eaters not on the drugs. While the amounts of the drug in produce-eater's pee were four orders of magnitude lower than what is seen in the pee of patients purposefully taking the drugs, researchers speculate that the trace amounts could still have health effects in some people, such as those with a genetic sensitivity to the drugs, pregnant women, children, and those who eat a lot of produce, such as vegetarians. And with the growing practice of reclaiming wastewater for crop irrigation -- particularly in places that face water shortages such as California, Israel, and Spain --- the produce contamination could become more common and more potent, the authors argue.

4 of 134 comments (clear)

  1. Re:Vegetarians at risk. by guises · · Score: 3, Insightful

    Bleh. Wish the original paper wasn't paywalled, this vegetarian business doesn't make a lot of sense to me. If you take that produce and feed it to animals, and then eat the animals, you should have at least as much exposure as from eating the produce straight. If the drug in question is one which bioaccumulates, then your exposure should be higher than it would be from eating the produce straight. It would be nice to see what the paper said specifically, rather than getting it second hand.

  2. Re:Vegetarians at risk. by techno-vampire · · Score: 5, Insightful

    If the drug in question is one which bioaccumulates...

    And that's the big question, isn't it? I hope somebody's looking into it, because without knowing how much it accumulates in the animal's bodies we can't judge how much of a concern it is. And, even if it isn't, the animal's waste products are probably being used as fertilizer, sending it right back into whatever crops it's used on. I'm not an alarmist, but we clearly need to know more about this.

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  3. Re:Vegetarians at risk. by PPH · · Score: 4, Insightful

    If the drug in question is one which bioaccumulates

    Then the original patient wouldn't be whizzing so much of it out.

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  4. Re:Vegetarians at risk. by khallow · · Score: 4, Insightful

    and discharges into water

    Which is a strong indication it does not bioaccumulate in humans. Another is that they use this chemical as a drug. A drug which bioaccumulates would quickly become a poison (eg, using mercury to treat syphilis) and would for one shot attempts at fixing illnesses not a long term medication for treating epileptic conditions.

    Now the human body is relatively good at dealing with toxins, so it may be that cows and whatnot might bioaccumulate this while humans do not. But I doubt that's happening.