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World's First Baby Born With New '3 Parent' Technique (newscientist.com)

A five-month-old baby boy has been revealed as the first kid in the world with three biological parents, reports New Scientist. The baby boy was apparently conceived by a technique that has been legally approved in the UK, and lets parents with genetic disorders have healthy babies. Though, the method used in this particular cases was slightly different from one legalized in the UK. From the report: Zhang (a doctor) took a different approach, called spindle nuclear transfer. He removed the nucleus from one of the mother's eggs and inserted it into a donor egg that had had its own nucleus removed. The resulting egg -- with nuclear DNA from the mother and mitochondrial DNA from a donor -- was then fertilised with the father's sperm. Zhang's team used this approach to create five embryos, only one of which developed normally. This embryo was implanted in the mother and the child was born nine months later. "It's exciting news," says Bert Smeets at Maastricht University in the Netherlands. The team will describe the findings at the American Society for Reproductive Medicine's Scientific Congress in Salt Lake City in October.

6 of 203 comments (clear)

  1. Re:Or they could have just adopted by ShanghaiBill · · Score: 3, Informative

    Hardly fair to call the baby malicious names even if you disapprove of this medical technique.

    The same thing happened back in 1978, when Louise Brown was born. Today everyone accepts IVF as routine. This time will be the same: The first baby is on the front page, the 2nd baby is mentioned on page 6, and the 3rd baby is ignored.

  2. Not meaningfully different from in-vitro by Junta · · Score: 3, Informative

    Yes, a lot of work went in, but ultimately, all of the *significant* genetic material came from two parents. Passing on your mitochondrial DNA doesn't do anything to really shape your offspring (unless your mitochondrial DNA is just *really* messed up). Now if the donor egg somehow had defective Mitocondrial DNA, ok, this is at least somewhat useful.

    But pretending this offspring has three equally biological parents is disingenuous.

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  3. Re:Call me strange but... by Anonymous Coward · · Score: 5, Informative

    Well TBH the summary omits the most major point of the thing. Which is the REASON WHY!
    Here, dear readers, is the reason why they did it:

    - The mom had been pregnant with about five other kids before. They all died early, before three years of age.
    - She has a condition that all her past babies are guaranteed to be born with, and remember they will all die early.
    - So that gene was removed from her eggs and replaced with a stable gene from another.
    - She gives birth to a disease free child.

    That's why it's "good news" to her and the doctors. Any exaggerative thoughts about super-babies, etc is just worrysome fodder.

    TL;DR? read the article.

  4. "First"? This was done in the 1990s. by jeffb+(2.718) · · Score: 5, Informative

    Okay, this may be the world's first baby, but there are apparently 30-50 teenagers with three parents.

    The girl with three biological parents

    The technique was pioneered in the late 1990s, but then the US FDA said "please cut it out", and as far as we know everyone did.

    So, yes, the future looks bright for this new baby, given that several dozen other beneficiaries of this technique seem to be doing quite well in their teenage years...

  5. Re:What selfish bastards by DRJlaw · · Score: 2, Informative

    RTFA. This procedure is illegal in the USA, so the parents went to Mexico. This baby IS an immigrant.

    1. The article says that this is a Jordanian couple who sought treatment from U.S. doctors, and that the U.S. doctors chose to perform their work in Mexico.

    2. The article doesn't suggest that anyone was an immigrant anywhere (def'n: "a person who comes to live permanently in a foreign country.). People appear to have temporarily traveled to do stuff, then returned to their respective homes. So, the baby is an immigrant to where? The parents' home country? Because?

    3. Finally, there's this little thing called citizenship by birth, which the not terribly reliable but readable-by-non-arabic-speaking-me source suggests is automatic for this child. Your own country, by definition, is not a foreign country, which means that you cannot be an immigrant to it. Similarly, for a child born abroad to a U.S. citizen parent in wedlock, odds are pretty good that they're already a U.S. citizen, falling on the "Nationality" side of the Immigration and Nationality Act.

  6. Re:Call me strange but... by MightyMartian · · Score: 3, Informative

    No, there are no such studies. There are studies confirming that a drop in oxygen levels to the brain, often concurrent with someone about to die, will lead to some pretty wild hallucinations, but what you wrote is just pure bullshit. There is nothing to indicate in any research that the mind is anything more than the sum of actions of several different parts of the brain.

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