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New Research Suggests the Appendix Has a Purpose After All (qz.com)

The appendix is an organ thought to have gone the way of our wisdom teeth and body hair: At one point we all needed them, now people can get by just fine without them. However, it turns out, at least the appendix has some purpose in the body. From a report: Scientists, though, have never been certain what the appendix used to do -- and if it is still, in fact, useless. On Jan. 9, a team of researchers led by scientists at Midwestern University Arizona College of Osteopathic Medicine published a review study proposing an answer: the appendix is a secondary immune function that both catalyzes immune cell responses and floods your gut with beneficial bacteria when they've been depleted. And it still plays that role, in a limited fashion, in human body function."We can function okay without it, but the appendix does provide some degree of immunity and beneficial bacteria,â Heather Smith, an anatomist and lead author of the paper said.

5 of 133 comments (clear)

  1. "News" by ledow · · Score: 5, Informative

    Not news.

    The appendix has MANY subtle jobs rather than one obvious one, that's why you can do without it.

    I've been telling people for 20+ years after reading it online that the appendix is PARTLY a store of stomach bacteria etc. to help reseed the stomach in the case of it being flushed during illness.

    People with appendices recover better from a bout of stomach flu and are less likely to get knock-on infections that those without. It's been in the medical literature for decades, at least, and been on this site at least twice I'm sure.

    It's also not the appendix's only job.

    This is not "news" at all.

    1. Re:"News" by ledow · · Score: 4, Informative

      Yep. Wikipedia has citations going back to 1989 for that.

  2. How is this news? by argStyopa · · Score: 5, Informative

    I've read about this role for the appendix for at least 5 years? At LEAST.

    Here's an early article I found on the subject https://blogs.scientificameric... - and if SciAm had it in 2012, it had to be relatively established information, they're not anywhere near cutting-edge reportage.

    And here's a Discover magazine thing saying the same thing in 2008: http://discovermagazine.com/20...

    --
    -Styopa
  3. White Blood Cells, part of the Immune System by CrashNBrn · · Score: 5, Informative
    The Appendix: Slimy But Not Worthless (2006)

    The appendix is a slimy, dead-end sac that hangs between the small and large intestines. It's about a half inch in diameter and three inches long. As quickly as 11 weeks after conception, the appendix starts making endocrine cells for the developing fetus. Endocrine cells secrete useful chemicals, such as hormones, and the appendix endocrine cells secrete amines and peptide hormones that help with biological checks and balances as the fetus grows.

    After birth, the appendix mainly helps the body stave off disease by serving as a lymphoid organ. Lymphoid organs, with their lymphoid tissue, make white blood cells and antibodies.

    The appendix, by virtue of its lymphoid tissue, is part of a complicated chain that makes B lymphocytes (one variety of white blood cell) and a class of antibodies known as immunoglobulin A antibodies. The appendix also produces certain chemicals that help direct the white blood cells to the parts of the body where they are needed the most.

    The dirty gut is a good training ground for young white blood cells. The appendix, with its sac routinely collecting and expelling foodstuffs, exposes the white blood cells to myriad bacteria, viruses and drugs passing through the gastrointestinal tract. This way, the white blood cells learn to fight potentially deadly bacteria, such as E.coli.

    The appendix's contribution to the body's white blood cell and antibody production reaches its peak when you are about 20 or 30 years old, then production falls off sharply. By age 60, the appendix serves very little active purpose. ...

    Emphasis mIne.

  4. Consider the source by tomhath · · Score: 3, Informative

    Midwestern University Arizona College of Osteopathic Medicine