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B Vitamins Reduce Schizophrenia Symptoms, Study Finds (newsmax.com)

A new study published in the journal Psychological Medicine finds that high doses of B vitamins reduce the symptoms of schizophrenia. Researchers found that using B vitamins, including B6, inositol, and B12 as an adjunctive with antipsychotics significantly improved symptoms of the debilitating condition. Newsmax reports: For the new study, researchers identified 18 clinical trials with a combined total of 832 patients receiving antipsychotic treatment for schizophrenia. They found that B-vitamin interventions which used higher dosages or combined several vitamins were consistently effective for reducing psychiatric symptoms, whereas those which used lower doses were ineffective. The evidence also suggested that B-vitamin supplements were most beneficial when they were added to medicine regimens early after diagnosis.

90 comments

  1. Ray Kurzweil by Anonymous Coward · · Score: 0

    That didn't seem to have worked for Mr Kurzweil, though.

    1. Re:Ray Kurzweil by Anonymous Coward · · Score: 0

      He was vegan.

    2. Re:Ray Kurzweil by Rei · · Score: 5, Interesting

      Funny, the only schizophrenic I've ever known was also vegan.

      I'm a vegetarian, and have strong sympathy for the motives behind being vegan. But take your B-12, my vegan friends. Unless you eat large amounts of soil, feces, or bacterial concentrates, or you've had a rumen implanted in your body, you need it. Higher plants don't make it. Every "vegetarian" mammal has to get it from somewhere, and those not lucky enough to have rumens (or other organs filling equivalent "cultivate lots of bacteria" roles) either get it through eating soil, feces, insects (accidentally or on purpose), or other such sources. Even our "strict" vegetarian gorilla relatives eat grubs. Heck, even though I consume dairy, I still take a B-12 supplement, just to ensure that I get enough.

      Also, B-12 shortage doesn't hit you immediately. The body stores about 5 years of B-12. So it'll catch up with you sooner or later.

      --
      I spent the evening flickering into your darkness.
    3. Re:Ray Kurzweil by Anonymous Coward · · Score: 0

      I hate taking vitamins. And so do I.

    4. Re:Ray Kurzweil by hawkinspeter · · Score: 1

      How about Silken Tofu - that's typically fortified with B-12

      --
      You're a temporary arrangement of matter sliding towards oblivion in a cold, uncaring universe
    5. Re:Ray Kurzweil by Anonymous Coward · · Score: 0

      All kinds of foods are fortified with all kinds of vitamins, so I'm not sure the whole B-12 vegan thing is an issue, practically speaking. You'd have to eat a much more restricted diet than just "vegan" for this to cause any problem.

      The number of reports of bona-fide B-12 deficiency in vegans that don't *also* accompany malnutrition seems to be virtually non-existent.

    6. Re:Ray Kurzweil by Anonymous Coward · · Score: 0

      I hate taking vitamins. And so do I.

      That's MPD dumbass.

    7. Re:Ray Kurzweil by hawkinspeter · · Score: 1

      It can be an issue as pretty much all sources of B-12 are meat and fish based, so a vegan is unlikely to get enough of it unless they make a special effort. Most foods aren't fortified with B-12 as B-12 deficiency is rare (unless you're a vegan). Also, as the body stores B-12 for about a year or so, it'll take a while for any deficiency to take effect.

      Isn't a B-12 deficient diet an example of malnutrition?

      --
      You're a temporary arrangement of matter sliding towards oblivion in a cold, uncaring universe
    8. Re:Ray Kurzweil by Mikkeles · · Score: 1

      He can still drink (unfiltred) beer.

      --
      Great minds think alike; fools seldom differ.
    9. Re:Ray Kurzweil by Anonymous Coward · · Score: 2, Funny

      Zymurgy is slavery! #YeastLivesMatter

    10. Re: Ray Kurzweil by Anonymous Coward · · Score: 0

      So, vegans are on pills. And those who aren't - either eat insects or become schizophrenic psychos. Good to know.

    11. Re:Ray Kurzweil by Anonymous Coward · · Score: 0

      meat and fish is redundant.

    12. Re:Ray Kurzweil by Khashishi · · Score: 1

      Those B-12 supplements usually have something like 36666% of the RDA per pill. So I just take them like once a week, and I figure I'm still getting plenty. I know I won't absorb all of the B12, but even if I absorb a couple percent, I'm good.

    13. Re:Ray Kurzweil by Rei · · Score: 1

      All kinds of foods are fortified with all kinds of vitamins

      The fact that a particular tofu manufacturer may fortify their product with B12 is only because they know that a lot of their market is vegan. Not all vegans eat tofu, or will pay attention to whether their brand does or does not fortify. Not all eat cereal either (the main "multivitamin-fortified" food that people consume), and a serving of a typical fortified cereal only provides about a quarter of your RDA anyway. Lots of other foods are fortified by specific nutrients, but rarely B12.

      --
      I spent the evening flickering into your darkness.
    14. Re:Ray Kurzweil by Rei · · Score: 1

      Yeah, it's crazy how much they put in them. The human body requires utterly miniscule amounts of B12. But the difference between "miniscule" and "none" has a big impact :)

      --
      I spent the evening flickering into your darkness.
    15. Re: Ray Kurzweil by Anonymous Coward · · Score: 0

      They say schizophrenia is actually 4 separate illnesses. I believe at least one of those four illnesses are caused by consuming soy, soy lecithin, wheat, dairy. Soy lecithin is found in everything, it's an emulsifier found in candy,most breads, vegetable oil, most processed foods. Also accompanying these brain allergies(which are related to the digestive system and its bacteria) is allergies to peanuts and nuts in general, egg yolks, whole grains, cilliac disease and lastly vitamin b deficiencies. I believe eliminating the problem by an avoidance diet can help a tremendous number of people. Throwing in vitamin b and fish oils can only help. Countries that consume the most fish and have the smallest inclusion of soy in there diet are correlative to low rates of schizophrenia, while the opposite is true in cultures consuming the most. Asian countries process soy before eating it, skewing correlation attempts. There is generally a lack of data on the subject, and there is a rapidly growing industry with soy making a strong pro soy advocacy and skewing studies toward short term benefits of soy consumption. Hospitals avoiding soy, wheat, and dairy released mental patients in half the length of stay.

    16. Re:Ray Kurzweil by elcor · · Score: 1

      I didn't know soil include B12, does that include eating clay?

    17. Re:Ray Kurzweil by Rei · · Score: 1

      I've not seen any reports on clay, but I wouldn't expect as much. It's soil bacteria that produce the B12, so you're looking for organic-rich soils.

      Animals that eat clay often do so to help neutralize toxic alkaloids and to get various mineral supplements.

      --
      I spent the evening flickering into your darkness.
    18. Re:Ray Kurzweil by Anonymous Coward · · Score: 0

      How much soil would you have to eat to get a day's or week's worth of B-12?

    19. Re:Ray Kurzweil by Rei · · Score: 1

      On the order of 15 micrograms per kilogram. Adult humans need 2.4 micrograms per day.

      --
      I spent the evening flickering into your darkness.
    20. Re:Ray Kurzweil by Coren22 · · Score: 1

      Last summer my doctor diagnosed me as being vitamin B (and D) deficient. I wasn't aware of the source of B-12 previously, but it makes me wonder how I could be B-12 deficient as I am an omnivore, and not on a restricted diet. But as you say below, I am American, and so don't eat very healthily to begin with.

      --
      APK likes to ask for responses to the same things over and over. Maybe he just likes the responses?
  2. Re:'Schizophrenia' is a normal reaction... by Anonymous Coward · · Score: 0

    Cool story bro.

  3. megavitamins by harvey+the+nerd · · Score: 2

    Megavitamins and orthomolecular medicine have a scientific basis that is more targetable than this indicates. Merely they've been under "fake news" attacks since at least the 1960s, when the psychiatric establishment of that time attacked with rigged results. Then the severely iatrogenic oncologists of the 70s and 80s attacked.

    Both of these self anointed establishments' actions and statements then, when viewed by today's information, to me look like quacks with criminal intent

    1. Re:megavitamins by Anonymous Coward · · Score: 0

      Megavitamins are all you need to make expensive urine.

    2. Re:megavitamins by Ambassador+Kosh · · Score: 1

      Very large doses of some vitamins can actually make you very sick or significantly increase your cancer risk. The most common thing is people that think that LOTS of antioxidants are good for them. The problem is that if you take too many your body can no longer destroy cancer cells with free radicals generated by macrophages. If you take antioxidants too far you significantly increase your risk of cancer and your risk for bacterial infection.

      There are also some fat soluble vitamins that are toxic if you take too much (like D).

      You do need vitamins and minerals and as our technology advances we can figure out how much you truly need but for now it is still important to use moderation.

      --
      Computer modeling for biotech drug manufacturing is HARD! :)
    3. Re:megavitamins by harvey+the+nerd · · Score: 1

      You look like an intelligent person with some common hearsay opinions contaminating your information base. Because of the structure of how these have been implanted over generations in the medical fields, most PhDs and MDs don't even begin to recognize their problem on accurate megavitamin information. Or where to start with the original scientific and medical papers. ...Very large doses of some vitamins can actually make you very sick or significantly increase your cancer risk Clearly not dealing with preferred forms and regimens of nutrients if that happens. There also is some skill, supervision or basic education missing if that happens. You might look at the old injectable vitamin C papers and the recent failures on vitamin D RDA setting (e.g. 200 iu D2 in 1992 vs 2000-5000 iu in 2017 for saavy arctic living) as a starting point. One clue: When someone speaks to me about "antioxidants" or an indiscriminate vitamin letter rather than the actual molecular entity, their credibility takes a big hit. The particular molecule(s), mixture or regimen can make a huge difference in megadose therapeutic situations.

    4. Re:megavitamins by Anonymous Coward · · Score: 0

      Perhaps you should have provided some concrete details yourself, then.

    5. Re:megavitamins by swell · · Score: 1

      Add to that the fact that vitamins and natural supplements can't be patented. This creates an immediate bias against them when pharmaceuticals become available for similar symptoms. Drug companies are known to influence the Food and Drug Administration (FDA) and the medical community to discourage the public from using natural supplements when there are prescription drugs available.

      Additionally, nobody can afford to invest the millions of dollars to prove the value of a particular vitamin, in the way that money is invested for patentable drugs. The tiny margin of profit for a vitamin can't justify such an investment.

      --
      ...omphaloskepsis often...
    6. Re:megavitamins by Slalomsk8er · · Score: 1

      There are also some fat soluble vitamins that are toxic if you take too much (like D).

      Yes, in general fat soluble vitamins have a higher potential of toxic accumulation. But how toxic is it?

      You can use about 50 000 IU per day for a long time with out symptoms.

      Taking 50,000 international units (IU) a day of vitamin D for several months has been shown to cause toxicity. This level is many times higher than the Recommended Dietary Allowance (RDA) for most adults of 600 IU of vitamin D a day. http://www.mayoclinic.org/heal...

      And even this information is old and the 600 IU RDA seams to be lacking. http://articles.mercola.com/si...

      New recommendations are at about 7 000 to 10 000 IU per Day with no access to sunlight at a UV-Index above 2.

    7. Re:megavitamins by nbritton · · Score: 1

      Perhaps you should have provided some concrete details yourself, then.

      He is right about the antioxidants. Research NRF2, from what I recall it is a negative feedback loop. The more Endogenous antioxidants you take the less exogenous antioxidants you make. This is bad because the bodies naturally produced antioxidants are better, in particular glutathione. Rather than taking endrogenous antioxidants, I recommend taking the prodrugs that your body needs to produce exogenous antioxidants. i.g. Acetylcysteine and Calcitriol (glutathione catalyst).

    8. Re:megavitamins by Anonymous Coward · · Score: 0

      Are you suggesting high doses of vitamins don't cause issues? I'd say you're a quack or don't know a thing about vitamin A. Vitamin A overdose can kill you regardless of what you take it with

    9. Re:megavitamins by harvey+the+nerd · · Score: 1

      There are several things that could be problematic if one is so uninformed, or determined to screw up. But, there are many times more treatments that are still surprising in both their dosage and benefits with a lack of adverse side effects.

      The right doses with the right molecules is the key concept that naysayers are determined to miss. Any moron can skip the instructions and do something silly/stupid.

    10. Re: megavitamins by Anonymous Coward · · Score: 0

      Glutathione is a triPeptide. Not well absorbed. May be broken down by digestion. NAC seems good, I have seen one report on negative affects, many on positive affects... It cancels acetaldehyde, whether from excess ethanol, or paracetamol.

    11. Re:megavitamins by Anonymous Coward · · Score: 0

      You should always take the D3 (cholecalciferol) vitamin with K2 (as Menaquinone-7) vitamin.
      K2 is the vitamin, that helps the D3 to manage the calcium in blood and bones.

    12. Re:megavitamins by Anonymous Coward · · Score: 0

      Good thing we still have publicly-funded science. For now, at least.

  4. Re:'Schizophrenia' is a normal reaction... by Megol · · Score: 2

    No it isn't. Schizophrenia is a hardware problem (though it can be triggered emotionally and/or with misc. drugs). While psychology is a hard problem to crack in general there are very strong evidence of the above and very little reliable evidence for the OPs idea.

  5. Re: 'Schizophrenia' is a normal reaction... by Anonymous Coward · · Score: 0

    The person should be in a secure hospital treated by professionally qualified doctors. Unfortunately many homeless people suffer from mental illness while others opportune from it as crazy as that is...it is a different pathology.

  6. Re:'Schizophrenia' is a normal reaction... by Anonymous Coward · · Score: 0

    No it is not. The voices told me so.

    Jokes aside - you are simply wrong.

  7. as an adjunctive with antipsychotics... by Anonymous Coward · · Score: 0

    yeah right adjunctive! First find me someone who has used antipsychotics that doesn't relapse into a far worse state within 12 months.

  8. Re:'Schizophrenia' is a normal reaction... by Gravis+Zero · · Score: 5, Informative

    Looks like someone doesn't know the difference between schizophrenia and multiple personality disorder. Also, the normal reaction to traumatic events is to black them out.

    Why are ACs always make such total asses of themselves? ;)

    --
    Anons need not reply. Questions end with a question mark.
  9. No "study find" by hcs_$reboot · · Score: 1

    but a balanced diet reduce many symptoms.

    --
    Slashdot, fix the reply notifications... You won't get away with it...
  10. No by Anonymous Coward · · Score: 0

    They hide the microphones in the pills! Don't do it!

  11. So what is the correct dosage by Anonymous Coward · · Score: 0

    From the article:
    "Researchers found that adding B vitamins, including B6, inositol, and B12 significantly improved symptoms of the debilitating condition."
    "They found that B-vitamin interventions which used higher dosages or combined several vitamins were consistently effective for reducing psychiatric symptoms, whereas those which used lower doses were ineffective."

    So which B Vitamins exactly and in what dosages?
    Are there side effects at those dosages?

    1. Re:So what is the correct dosage by Big+Hairy+Ian · · Score: 1

      So which B Vitamins exactly and in what dosages? Are there side effects at those dosages?

      The articles specify B6, B8 & B12. As for the qty the article only specifies large doses which is clinically fucking useless.

      --

      Build a Man a Fire, and He'll Be Warm for a Day. Set a Man on Fire, and He'll Be Warm for the Rest of His Life.

    2. Re:So what is the correct dosage by Anonymous Coward · · Score: 0

      The scholarly article in THE FIRST FUCKING LINK discusses body weight calibrated dosages, but you'd have to not be the typical Slashdot doofus skinflint and actually pay for access to it to find out.

      Apparently all you are willing to pay attention to is the article from the conservative version of the National Enquirer that follows.

    3. Re:So what is the correct dosage by Anonymous Coward · · Score: 0

      Both links state B vitamins INCLUDING B6, B8, & B12. That implies that there are other unstated B vitamins that also help.
      And no I don't pay for access to Psychological Medicine articles before posting on Slashdot.

  12. Beer by Anonymous Coward · · Score: 0

    Is always the answer regardless the question

    1. Re:Beer by Anonymous Coward · · Score: 0

      Amen to that !

  13. Re:'Schizophrenia' is a normal reaction... by drinkypoo · · Score: 1

    Schizophrenia is a hardware problem (though it can be triggered emotionally and/or with misc. drugs).

    In humans, the line between hardware and software is indelible. Or, you might just say that it's squishy and permeable.

    --
    "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
  14. Confidence Intervals... by RatPh!nk · · Score: 1

    Pooled effects showed that vitamin B supplementation (including B6, B8 and B12) reduced psychiatric symptoms significantly more than control conditions [g = 0.508, 95% confidence interval (CI) 0.01–1.01, p = 0.047, I2 = 72.3%]. Similar effects were observed among vitamin B RCTs which used intention-to-treat analyses (g = 0.734, 95% CI 0.00–1.49, p = 0.051).

    The confidence interval indicates the level of uncertainty around the measure of effect (precision of the effect estimate). Confidence intervals are used because a study recruits only a small sample of the overall population so by having an upper and lower confidence limit we can infer that the true population effect lies between these two points. Most studies report the 95% confidence interval (95%CI). If the confidence interval crosses 1 that implies there is no difference between arms of the study. As far as I can remember.

    --
    Argh. The laws of science be a harsh mistress.
    1. Re:Confidence Intervals... by Anonymous Coward · · Score: 0

      Yeap, CI including 1 basically means there is no difference in the two samples.

      Also p-values indicate there is 5% chance the results observed are there, well, by chance (1 in 20 researchers would find that by collecting random data).

      So yeah, nothing to see here.

  15. Re: 'Schizophrenia' is a normal reaction... by drewsup · · Score: 3, Insightful

    I would reverse that statement to read
    "many schizophrenics suffer from homelessness"
    Most have drug problems trying to combat the symptoms, nit the other way around.
    You see the lies propagated in anti marijuana stories that cite " look, he's a schizophrenic because he smokes weed, when the opposite is closer to the truth, they are self medicating.

  16. Re:'Schizophrenia' is a normal reaction... by Maritz · · Score: 2

    Well what have we here. Looks like I must update my mental definition of 'schizophrenia' based on what this AC said. Forget all the stuff about paranoid delusions, scary auditory and visual hallucinations, etc - it's "a description for a set of behaviours that are viewed as abnormal ALL caused by traumatic events during childhood".

    Thanks AC. Can I quote you?

    --
    I do not want your cheap brainburning drugs. They are useless for work. And I am a working man today.
  17. Undecided by Anonymous Coward · · Score: 0

    I've always been in two minds whether to take vitamins or not...

  18. Re:'Schizophrenia' is a normal reaction... by Anonymous Coward · · Score: 0

    "indelible"? Huh?

  19. B-Complex is good generally by RubberDogBone · · Score: 1

    A B-Complex supplement is a good idea anyway, as B vitamins get peed out and don't stay in the body for too long.

    So it is really hard to end up with not enough of them over a very short period of time and minor changes in diet can mean missing out.

    B-12 is also depleted by certain medications like Metformin, one of the main Type 2 Diabetes treatments. If you take Metformin, you are automatically low on B-12 and you will need to take more every day. You cannot eat enough food to reach the level you need.

    Costco's Kirkland B-Complex is a very good one and packs more punch for less cost than other more common grocery store brands. But even with that, you would still need a B-12 standalone. Costco sells that too.

    --
    Sig for hire.
    1. Re:B-Complex is good generally by religionofpeas · · Score: 1

      B vitamins get peed out and don't stay in the body for too long.

      B-12, one of vitamines mentioned, is stored in the liver for years.

  20. Energy Drinks by Anonymous Coward · · Score: 0

    Weirdly, another study showed high niacin in energy drinks was hurting health of people consuming more than 2 in a 2-day period.
    Can lead to hepatitis over longer periods.
    And even killing in excessive levels.

    B vitamins are indeed complex.

    1. Re:Energy Drinks by ChrisMaple · · Score: 1

      My memory is hazy on this point, but IIRC it's the niacinamide form of B3 that is a risk for liver damage (in large doses, over time.) Niacin causes skin flushing (feels like a sunburn) in large doses, which tends to discourage overuse - but flushing varies a lot by individual. The RDA is below 20 mg / day, and most adults can easily take 10 times more.

      --
      Contribute to civilization: ari.aynrand.org/donate
    2. Re:Energy Drinks by Anonymous Coward · · Score: 0

      I started taking B vitamins to increase my energy levels. I started with a 100% recommendation B vitamin complex. After a week or so noticed some improvement and then decided to start taking individual B vitamins to get higher doses.

      I got individual B1, B3, B6 and B12. It was cost effective to buy the 1000mg B3/Niacin mega bottle, but I did end up experiencing the skin flushing and sunburn pins and needles tingling feeling everywhere. I gave up both B1 and B3 and now only take B6 and B12 in the morning.

      I ride 9 miles on a bicycle to work everyday that it is above freezing and not raining, and taking the B vitamins decreased my time to work by about a minute. I added Aleve to the two vitamins in the morning so I wouldn't be suffering from too much leg pain that makes it difficult to walk around for the first 30 minutes or more and to my surprise, within 2 weeks of starting Aleve with the vitamins, I had reduced my average time by more than 3 minutes.

      I think it has to do more with the sodium in Aleve than the naproxen pain relief. YMMV but I would suggest if you are active and want to perform better, try the B6, B12, 220mg of Aleve combination.

      captcha: switched

  21. Smoking = nicotine = nicotinic acid? by omnichad · · Score: 1

    And is smoking just a way of getting nicotinic acid as a byproduct (aka Niacin aka Vitamin B3)?

    1. Re:Smoking = nicotine = nicotinic acid? by Anonymous Coward · · Score: 0

      I hope your not also pushing Cal-Mag, we all know that L.Ron Hubbard thought lung cancer was caused by not smoking enough,

  22. Re:'Schizophrenia' is a normal reaction... by wbr1 · · Score: 1

    Why are ACs always make such total asses of themselves? ;)

    Maybe schizophrenia?

    --
    Silence is a state of mime.
  23. Re:'Schizophrenia' is a normal reaction... by drinkypoo · · Score: 1

    "indelible"? Huh?

    Yeah, you're right. That's not the word I wanted. It's vaguely in the right ballpark, and I didn't sleep well. I wanted something about how they were in inseparable, and then a line got involved somehow...

    --
    "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
  24. Re:'Schizophrenia' is a normal reaction... by Anonymous Coward · · Score: 0

    You're the one with multiple personalities. That fake name of yours you use here is on your birth certificate? Who's the nutcase here?? You are with your childish fantasyland name! Grow up, act your age, and be yourself instead, alright?

  25. Usual caveats by Anonymous Coward · · Score: 0

    One is the basic issue that, without proper understanding of how one 'instance' of schizophrenia differs from another, and the degree to which 'what works' differs from both person to person, and depending upon the particular details of the 'instance' of schizophrenia (I use the class/instance analogue, since people on /. are used to it: schizophrenia is kind of an abstract base class, paranoid schizophrenia is an abstract subclass of it, and a particular person's schizophrenia is an instance of some subclass of schizophrenia, possibly inheriting from various 'well known' forms.)

    Doing this is hard, and will generally show mental health research in a far poorer light, and of course is not required of current researchers, which is why it is hardly ever thought of, let alone mentioned. But not doing this is akin to the schoolboy error of omitting experimental error, and ignoring the question of how well the subject of a study fits the assumed theoretical model.

    So far, the degree to which two 'instances' of schizophrenia can be thought of as the 'same thing' has yet to be properly shown (that is, 'same' to a sufficient degree that it makes sense to talk of 'treatments for schizophrenia', rather than 'treatment for a particular schizophrenia'). And almost all research into treatment of schizophrenia effectively already assumes this, together with strong implicit assumptions as to the variability of people and conditions which attract the label 'schizophrenia'. The effect, from the point of view of trials such as mentioned in TFA, is that results are averaged across all instances (and from the point of view of what 'the literature' appears to show, biased according to what is and is not published -- another source of error that must be taken into account when inferring efficacy from surveys of the literature). The 'Emperor's New Clothes' problem in mainstream psychiatry is that nobody wants to see what their 'emperor' is actually wearing (i.e. bugger all).

    Until we get it into our heads that labels like 'schizophrenia' do _not_ tell us what a particular problem is, but merely tell us that certain symptoms have been observed by qualified psychiatric professionals, (and essentially nothing more), and that details as to the variability of one instance of a psychiatric illness to another, and the variability from one person to another, are properly taken into account, trusting current research is a game of Russian Roulette, and, thanks to the antics of Big Pharma, the 'research literature' has been turned into an 'academic medical shopping channel'.

    End rant.

  26. Re:'Schizophrenia' is a normal reaction... by nbritton · · Score: 1

    Schizophrenia is a hardware problem (though it can be triggered emotionally and/or with misc. drugs).

    In humans, the line between hardware and software is indelible. Or, you might just say that it's squishy and permeable.

    It would be better to think of the brain in terms of a FPGA because there is no higher ordered operating system software that is running on the hardware.

  27. Re:'Schizophrenia' is a normal reaction... by Anonymous Coward · · Score: 0

    Where is the research showing that _every_ case of schizophrenia is definitely a 'hardware problem'? Unlike in maths and physics, it seems nobody in mental health research can point to convincing evidence for critical parts of the reasoning process. First, are two cases of schizophrenia the same? Second, is it safe to neglect differences between people with schizophrenia such that trials of 'treatments for schizophrenia' makes sense? (This second one is equivalent to the 'is your equivalence relation well-defined' question mathematicians are familiar with: check the maths behind the stats used in mental health research, and pick through the logic carefully, and you'll see implicit assumptions of this staring back at you.)

    And third, where is the convincing research that schizophrenia is indeed a 'hardware problem'? (Convincing to someone with a hard science/maths background, not a medicine grad.)

  28. not a real disease by Anonymous Coward · · Score: 0

    its a catchall bullshit thing when doctors dont know. its based solely on pateints self-reported systems which are very easily misinterpreted by psychiatrists

  29. Re:'Schizophrenia' is a normal reaction... by Anonymous Coward · · Score: 0

    It's in our name, when you pronounce AC with a soft C. Duh!

  30. Re:'Schizophrenia' is a normal reaction... by Swave+An+deBwoner · · Score: 1
    Yes indeed, it looks like someone doesn't know the difference.

    https://www.nimh.nih.gov/health/publications/schizophrenia-booklet/index.shtml

    Voices” (auditory hallucinations) are the most common type of hallucination in schizophrenia. Many people with the disorder hear voices. The voices can either be internal, seeming to come from within one’s own mind, or they can be external, in which case they can seem to be as real as another person speaking.

    This post brought to you by the "Department of Pot Kettle Black" :-)

  31. Re:'Schizophrenia' is a normal reaction... by Swave+An+deBwoner · · Score: 1

    Hmmmm. Or was the parent post you were replying to something other than what I thought it was? The thread appears to point to a post that is not relevant to what you wrote. Sorry if I misconstrued your meaning.

  32. Vitamin B12 was recommended as a "rescue" for LSD by Swave+An+deBwoner · · Score: 1

    I recall that many, many years ago vitamin B12 was recommended as a rescue for a bad LSD trip. I don't know of any actual studies that tested its effectiveness though.

  33. NO EFFECTS FROM INOSITOL by Anonymous Coward · · Score: 0

    Here's what the abstract says:

    "There were no overall effects from antioxidant vitamins, inositol or dietary minerals on psychiatric symptoms."

    ====> Never trust a study that hides behind a paywall. ====

  34. Re:'Schizophrenia' is a normal reaction... by drinkypoo · · Score: 1

    It would be better to think of the brain in terms of a FPGA because there is no higher ordered operating system software that is running on the hardware.

    Yes, I like that very much. Then again, what's on an FPGA (or in any other circuit) can be written down in terms of a software program...

    --
    "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
  35. The study shows almost no difference from placebo by Anonymous Coward · · Score: 0

    I just read the study in question.

    It was a meta-analysis of multiple previous studies. Almost all of the studies used the positive and negative PANSS scales, which ranks severity of symptoms on a a 49 point scale. The strong majority of the included studies showed no difference between vitamin supplementation and placebo. A couple of the outliers shows about a 1 point improvement on the 49 point scale with the vitamins.

    Looking at the whole of the paper, it seems that most studies do no support the use of vitamins in the treatment of schizophrenia. There have been a couple of studies which should a small, statistically significant improvement with B vitamins, although it's questionable whether this improvement is clinically significant. Given the many studies which showed no difference from placebo, it's also possible that the positive studies simply represent publication bias.

    While it's unlikely to hurt anyone to take some vitamins, nothing in any of the studies or meta-analysis suggests that vitamins can effectively treat schizophrenia.

  36. Re: 'Schizophrenia' is a normal reaction... by bill_mcgonigle · · Score: 1

    Yes, you can diagnose and even predict with brain imaging. Search Medline.

    If there is another condition that's not visible on imaging then it's a separate disease, even if both are called the same thing clinically.

    --
    My God, it's Full of Source!
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  37. Re:'Schizophrenia' is a normal reaction... by Anonymous Coward · · Score: 0

    i think they do it so you can delusionally boost your ego on low hanging fruit

  38. Re:'Schizophrenia' is a normal reaction... by Khashishi · · Score: 1

    I thought the whole repressed memory thing was a complete myth. Aren't you way more likely to remember a traumatic memory than a mundane one?

  39. Mark this day in history by Anonymous Coward · · Score: 0

    A vegetarian finally admitted that they still need to take vitamin supplements.

    1. Re:Mark this day in history by Rei · · Score: 1

      Vegans do. Vegetarians can get it from milk and eggs.

      And hey, that can be turned around if you want to play that game. Your typical American eats var too few vegetables and so misses out on a lot of the plant-associated vitamins and minerals.

      --
      I spent the evening flickering into your darkness.
    2. Re:Mark this day in history by Anonymous Coward · · Score: 0

      The B-12 argument is frequently used in an attempt to "debunk" veganism as something "un-natural".

      Veganism is a philosophy which eschews use of animal products to the maxim extent possible. It has nothing to do with "natural" food, non-GMOs, personal health, feminism, social justice, or anything else. It's not a form of religious or personal purity like Kosher or Halal. All of that may be well and good, but is *not* veganism.

      Veganism is about making a *best effort* to take the path of least harm whenever *possible*. It's not about perfection.

      I don't get why this issue gets so much attention. Vegans know they need B-12, and they supplement it with fortified foods or vitamins. -- ie. "nothing to see", and move on.

  40. Re:'Schizophrenia' is a normal reaction... by Anonymous Coward · · Score: 0

    Yeah as our brain systems are linked together. More associations (more emotions) = higher recall and higher chance of continued recall (less forgetting). It's how memory experts do what they do

  41. Re:'Schizophrenia' is a normal reaction... by Antique+Geekmeister · · Score: 1

    > Yes, I like that very much. Then again, what's on an FPGA (or in any other circuit) can be written down in terms of a software program.

    This is demonstrably untrue for brains. Part of the key to a digital circuit, and program, is that it is deterministic. The same program run twice with the same nputs will produce the same output, and most of them can be modeled as Turing machines, so that they can be run on other hardware with sufficient resources.

    I'm afraid that nerves are _analog_, with triggered changes of state that cannot be reliably predicted. And there are indeterminacy issues, where the effect of applying a probe or measuring tool to record one neural pattern actually modifies the neural pattern. Writing that as a software program is quite difficult.

  42. In 1970's Adelle Davis Said and Published This by Anonymous Coward · · Score: 0

    The Dietician Adelle Davis Said This in the 1970's In her books, describing how B vitamins shortage can induce schizophrenia and how to treat it.

  43. Re:'Schizophrenia' is a normal reaction... by Gravis+Zero · · Score: 1

    Nope. It's rare but it's how your brain copes with extreme trauma. You are correct that you are likely to remember traumatic events but that just means that's your brain hasn't reacted to the trauma, it's treating them as normal events. The more intense the experience, the more neural connections, so the more you remember it.

    --
    Anons need not reply. Questions end with a question mark.
  44. Re:'Schizophrenia' is a normal reaction... by indi0144 · · Score: 1

    Tell that to people born schizoprenic : https://www.youtube.com/watch?...

    But judging by the quality of your tap water, yeah most babies are born with PTSD right now. At least now we know this is entirely hereditary, luck of the drawer of sorts, but whats your excuse to don't even fucking know what schizophrenia is? feelings? trauma? These are people hallucinating shit 24/7, this is some brain malfunction where it literally flips the bird to your senses and proceeds to mix shit at random in the buffer before your perception.

    Sound like someone's salty with schizos, takes a special kind of loser to hold any grief against people not completely aware of their self.

  45. Re:'Schizophrenia' is a normal reaction... by Coren22 · · Score: 1

    No, but that fake name is proper security procedure. The people using their real names on the internet are the odd ones.

    https://thecybersafetylady.com...

    Or are you intending to start posting under your own name instead of AC?

    --
    APK likes to ask for responses to the same things over and over. Maybe he just likes the responses?
  46. Re:'Schizophrenia' is a normal reaction... by Coren22 · · Score: 1

    OMG, Nimh exists! Keep the rats away from them or there might be trouble.

    --
    APK likes to ask for responses to the same things over and over. Maybe he just likes the responses?