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SpaceX's Next Launch Carries Colonies Of A Drug-Resistant Superbug (businessinsider.com.au)

An anonymous reader quotes Business Insider: SpaceX is preparing to launch a lethal, antibiotic-resistant superbug into orbit...to live its days in the microgravity environment of the International Space Station. The idea is not to weaponize space with MRSA -- a bacterium that kills more Americans every year than HIV/AIDS, Parkinson's disease, emphysema, and homicide combined -- but to send its mutation rates into hyperdrive, allowing scientists to see the pathogen's next moves well before they appear on Earth. The NASA-funded study will see SpaceX's Falcon 9 rocket launch colonies of MRSA into space, to be cultivated in the US National Laboratory on the International Space Station.

"We will leverage the microgravity environment on the ISS to accelerate the Precision Medicine revolution here on Earth," lead researcher Anita Goel, CEO of biotech company Nanobiosym, told Yahoo News... "Our ability to anticipate drug-resistant mutations with Gene-RADAR will lead to next generation antibiotics that are more precisely tailored to stop the spread of the world's most dangerous pathogens," says Goel.

That launch was scheduled for today, but SpaceX postponed it to "take a closer look at positioning of the second stage engine nozzle." [UPDATE: The launch was completed successfully on Sunday.] Two more externally-mounted payloads will conduct other experiments, with one monitoring lightning strikes on earth and the other measuring chemicals in the earth's atmosphere. In addition, there's also 21 science experiments that were submitted by high school students

Meanwhile, Slashdot reader tomhath brings news that researchers have discovered the red berries of a U.S. weed can help fight superbugs. The researchers found "extracts from the Brazilian peppertree, which traditional healers in the Amazon have used for hundreds of years to treat skin and soft-tissue infections, have the power to stop methicillin-resistant MRSA infections in mice." One of the researchers said the extract "weakens the bacteria so the mouse's own defenses work better."

56 comments

  1. Oh, God, I saw this show by Ken_g6 · · Score: 1

    ...in reruns. "Kill Zone", an episode of the original MacGyver. Although I wouldn't recommend the episode to anyone.

    Simply put, it ends up like this episode of Star Trek TNG, but without a transporter to fix things in the end.

    --
    (T>t && O(n)--) == sqrt(666)
    1. Re:Oh, God, I saw this show by lobiusmoop · · Score: 4, Funny

      I'm more 'old school' so was thinking Andromeda Strain

      --
      "I bless every day that I continue to live, for every day is pure profit."
    2. Re:Oh, God, I saw this show by Gription · · Score: 1

      Yeah it is important to seed new planets with the worst thing you can think of. We need to make sure they have as bad of horror movies as we do!

    3. Re:Oh, God, I saw this show by rholtzjr · · Score: 1

      Yea, I read this and said to myself, "Now what could ever go wrong with this?".

    4. Re: Oh, God, I saw this show by Anonymous Coward · · Score: 0

      whats an indo-chimp? am i one? can I be one? if I am one, how can I stop being one?

    5. Re:Oh, God, I saw this show by Nostalgia4Infinity · · Score: 1

      Or like this (The Expanse) https://www.youtube.com/watch?...

  2. Efficient Distribution Mechanism by Anonymous Coward · · Score: 1, Funny

    Given SpaceX history of detonating rockets, it seems like the probability of it becoming an efficient mechanism for distributing MRSA over the Earth's surface is not insignificant.

    1. Re:Efficient Distribution Mechanism by Anonymous Coward · · Score: 0

      Wow, didn't know MRSA was resistant to temperatures that cause an instantaneous state change from solid to boiling. We should be researching MSRA in more depth and figure out how we can take advantage of this superstate living organism!

    2. Re:Efficient Distribution Mechanism by murdocj · · Score: 1

      don't you know that even nuclear explosions don't kill these things, it just fuels them? Haven't you read the Andromeda Strain??

    3. Re: Efficient Distribution Mechanism by Anonymous Coward · · Score: 0

      Something like the leidenfrost effect kicks in making a cushion of gas between the explosion and the MRSA expelling it away from the explosion.

      And I, for one, welcome our new multi resistant bacteria overlords.

    4. Re: Efficient Distribution Mechanism by Anonymous Coward · · Score: 0

      Most chemical and biological weapons use a (small) explosive charge called a burster charge to spread the agent.

    5. Re:Efficient Distribution Mechanism by edxwelch · · Score: 1

      No, no, it's perfectly safe - now that they got rid of those pesky "roof snipers"

    6. Re: Efficient Distribution Mechanism by ColdWetDog · · Score: 1

      A ballistic missile seems a bit overkill (so to speak) for that mission.

      --
      Faster! Faster! Faster would be better!
  3. Waiting for the hypocrites by quonset · · Score: 1, Funny

    "extracts from the Brazilian peppertree, which traditional healers in the Amazon have used for hundreds of years to treat skin and soft-tissue infections, have the power to stop methicillin-resistant MRSA infections in mice."

    There will be those who will cheer this by saying we should look at more plants (or weeds in this case) and do more extracts to try and find ways to help people, but on the other hand will vehemently oppose trying to extract anything from marijuana which might help people because then that's someone trying to make a profit off a plant.

    1. Re:Waiting for the hypocrites by swell · · Score: 3, Insightful

      Well we do look at more plants. On every part of earth and under the sea. Aspirin was derived from a plant, and a fine example of how a natural substance can be patented and earn millions of dollars. It's a gold rush. Anthropologists inquire about native medicines worldwide. All in the interest of corporate greed.

      You see, natural substances can't be patented. They are worthless. If dandelions could cure cancer, no advanced corporation would take an interest. But they would analyze every molecule of the plant to find a specific one that did the job--and patent that. Once they have a product to sell at a great profit, they will spread FUD to prevent people from using real dandelions to cure their disease.

      --
      ...omphaloskepsis often...
    2. Re:Waiting for the hypocrites by quonset · · Score: 1

      Once they have a product to sell at a great profit, they will spread FUD to prevent people from using real dandelions to cure their disease.

      Like they do with aspirin so people won't use willow bark?

    3. Re:Waiting for the hypocrites by swell · · Score: 2

      Don't be an ass. There is no patent on aspirin at this time.

      --
      ...omphaloskepsis often...
    4. Re:Waiting for the hypocrites by quonset · · Score: 1

      Don't be an ass. There is no patent on aspirin at this time.

      But there was, wasn't there? Big Pharma patented an extract from a plant and made people pay for it during which time they spread FUD so people wouldn't use real willow bark to cure their headaches, didn't they?

    5. Re:Waiting for the hypocrites by Anonymous Coward · · Score: 0

      We used to say, "Solar energy will become popular when Exxon owns the sun".

      There are plenty of plants out there known to cure most everything that makes you sick, cancer included,>br>
      but Monsanto and big Pharma don't own those plants, so you won't see any pill to kill their awesome special super-secret superbug anytime soon.

    6. Re:Waiting for the hypocrites by Namarrgon · · Score: 1

      Not so much. For one, willow bark contains salicin, and though it has been used since Egyptian times, is less potent and causes side effects like gastric distress and potentially heart issues. Salicylic acid is a more potent extract, but still causes side effects. Aspirin is a derivation of this - acetylsalicylic acid, which eliminated most of the side effects but wasn't medically tested until nearly 1900.

      ASA was ineligible for patenting in its country of discovery (Germany), but was patented in the UK and US. I'm unaware of any FUD or other efforts to discourage the use of willow bark though, and it's unlikely that anyone would bother, due to aspirin's much greater effectiveness, lower side effects, and the intense bitterness of willow.

      --
      Why would anyone engrave "Elbereth"?
    7. Re: Waiting for the hypocrites by Anonymous Coward · · Score: 0

      Yeah, because it's absolutely worthless to spend hundreds of millions to isolate the compound that actually does the work and synthesize it at industrial scales, rather than deforesting the amazon for the "natural" version that is less effective.

      You may not be a fan of pharmaceutical companies, and god knows they've given plenty of reasons to piss people off, but they have saved countless lives, and developed drugs that have made massively expensive surgeries unnecessary. Yeah, I know, evil corporations and evil patents. Tell that to people that are alive due to these drug advances.

    8. Re:Waiting for the hypocrites by swell · · Score: 1

      Bayer established themselves as a powerhouse in pharmaceuticals with aspirin. Much in Bayer's history is controversial.

      None of this is directly related to my point that patents are critical for funding in corporations and for research and ultimate acceptance by government and the medical establishment. Items that are unpatentable (vitamins, etc) do not get major research funding and rarely get the publicity of patented drugs.

      --
      ...omphaloskepsis often...
    9. Re:Waiting for the hypocrites by Anonymous Coward · · Score: 0

      Nope - can't patent a molecule. Simply not an option.

      Big Pharma tends to patent a particular way to synthesize such a molecule instead. Being a technical process, the synthesis can be protected. But that generally requires significant work. Aspirin is pretty trivial (heck, I did that in high school) but other molecules are far harder to make.

    10. Re:Waiting for the hypocrites by Anonymous Coward · · Score: 0

      Well, at least the mice are now safe.

  4. No need for microgravity to accelerate mutation by coldandcalculating · · Score: 3, Informative

    Strains of bacteria defective for DNA repair enzymes have been used for years to accelerate lab studies of antibiotic resistance. There are even mutator strains of staph aureus that have been used for studies like this.

    1. Re:No need for microgravity to accelerate mutation by Anonymous Coward · · Score: 0

      More sensationalistic nonsense. A trip to space for MRSA makes a nice attention-grabbing headline but none of this is necessary as you point out.

    2. Re:No need for microgravity to accelerate mutation by lazy+genes · · Score: 0

      They only need to take a look at the local grade school. I had to attend a meeting at one and could see viruses the size of mosquitoes.

    3. Re:No need for microgravity to accelerate mutation by Anonymous Coward · · Score: 0

      Additionally, changing its environment is going to lead to different paths for evolution than if it had stayed on earth.

      I can't see any good reason for this study, other than to kill astronauts.

  5. This just sounds like a bad idea. by mmell · · Score: 1

    I mean, wasn't this the plot of numerous bad sci-fi movies back in the sixties and seventies? Oh, and at least one really good one.

    1. Re:This just sounds like a bad idea. by PPH · · Score: 1

      Someone forgot the tag: whatcouldpossiblygowrong

      --
      Have gnu, will travel.
  6. And I'm going to leverage... by Godwin+O'Hitler · · Score: 2

    ...the sandwich on my plate to decelerate my hunger. After that I'm going to leverage the lever on my handlebar to leverage the deceleration of my bike.

    --
    No, your children are not the special ones. Nor are your pets.
    1. Re:And I'm going to leverage... by Anonymous Coward · · Score: 0

      "...the sandwich on my plate to decelerate my hunger."
      After that, you're going to leverage the handle on your toilet to accelerate your poo. FTFY.

  7. I'm literally shaken, not stirred. by Anonymous Coward · · Score: 1

    AI, robot cars, and now space irradiate deadly bacteria?! Elon musk is a god damned Bond villain.

    1. Re:I'm literally shaken, not stirred. by murdocj · · Score: 1

      He's laughing in his secret underground lair in the Brazilian jungle right now

    2. Re:I'm literally shaken, not stirred. by Anonymous Coward · · Score: 0

      Which he's got to settle for for a few years yet, because finding just the right volcano for the lair is hard, and it just won't do to have any less than Olympus Mons.

    3. Re:I'm literally shaken, not stirred. by SuperDre · · Score: 1

      This is not Musk his project, all Musk does is deliver the cargo, the actual project is by NASA..

  8. Next into space by Anonymous Coward · · Score: 0

    ....Jock Itch

    The galaxy will thank us in a million years when its decendants conquer the universe ..

  9. Before the loons get to it. by caferace · · Score: 1

    Trump conspires with Musk up to have the rocket explode over the Soviet Union.

    1. Re:Before the loons get to it. by Spaham · · Score: 1

      The heat would probably destroy any living organism...

    2. Re:Before the loons get to it. by Dog-Cow · · Score: 1

      It's a time machine, too?

    3. Re:Before the loons get to it. by Anonymous Coward · · Score: 0

      haha, that was pretty funny. If I had modpoints, I would give +1 funny.

      It took me a few seconds to realise what you meant, though. Shows my age, I guess. For a large part of my life, it *was* the USSR. :-o

  10. launching a deadly pathogen into space? by Anonymous Coward · · Score: 0

    what could possibly go wrong?

  11. Stupid by Anonymous Coward · · Score: 0

    You don't need to send it to space to make it strong. Just give it more antibiotics, subject it to radiation, heat, cold, and the kitchen sink. This is why NASA is full of idiots

  12. Andromedae Strain by Anonymous Coward · · Score: 0

    Stupidity happens!

  13. I saw it in a movie, by backslashdot · · Score: 1

    so it must be possible. Movie writers are scientists.

  14. I haven't read the article, but... by wwalker · · Score: 1

    Am I the only one thinking this is pointless, as far as the proposed reasoning for this experiment is concerned? My guess is that this is an experiment just to see what happens (like most other science experiments), but it was sold to the higher-ups responsible for funding this project (and possibly the general public) with easy-to-understand, but completely pointless premise. It's pointless for at least two reasons:

    1) Mutations are *random*. There is no predetermined path that evolution will take place. Otherwise every isolated continent would have had the exact same set of animals/birds/insects/etc., as they all started from the same primordial slime. It's like looking at the previous lottery numbers to decide what to play in the next lottery. Completely pointless, but doesn't stop people from developing "strategies". The only thing you can predict is that the evolved bacteria will be different and will be better/fitter at surviving. How different and for what reason better/fitter -- there is no predicting that as there are literally billions upon billions of ways it can go.

    2) Conditions in space will be quite different from down here. It's called "survival of the fittest". "Fittest" for the specific conditions we have down here. MRSA bacteria lives and survives in and around people. Moreover, it lives and survives in and around people treated with various antibiotics. Whatever will survive up there in space will be "fittest" for those conditions, and will likely be nothing like what we'll see in real hospitals. I mean, they might as well get a petri dish and take an X-ray of it every 10 minutes and see what happens, to get fast mutations. No need to send anything into space. Not for that reason.

    Again, I'm not poopooing the experiment, I'm just saying I hope whoever is running it is not delusional. Or at least smarter than me. Or is it I? As you see, the bar is pretty low, so I'm hopeful. :)

  15. Bacteriophages anyone ? by Anonymous Coward · · Score: 0

    For every single bacteria there are phages which easily would kill them. Instead of investing there which would be clever but less profitable for big pharma, you still go for the now almost completely useless and organs harming antibiotics. If I had the money, I would hugely invest in building up a bacteriophage specialized company.

  16. Wait, what? by Anonymous Coward · · Score: 0

    How does this help anything? Wouldn't the spacefaring MRSA undergo different selection pressures compared to the MRSA living on some nursing home resident, and thereby have a different "next move?"

  17. The worst part by Anonymous Coward · · Score: 0

    Will be when they get out, get dumped to save the crew, and then gain a resistance to re-entry.

    Next thing we know even "kill it with fire" stops working

  18. Security Safety by jraff2 · · Score: 1

    Make damn sure it's in an unbreakable container. Accidents do happen, and you don't want MRSA to get loose on the ISS!

  19. Cosmic Rays? by Anonymous Coward · · Score: 0

    It's already a super bug. Cosmic Ray mutations are redundant.

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  21. we've all seen by sad_ · · Score: 1

    the blob!

    --
    On a long enough timeline, the survival rate for everyone drops to zero.
  22. FUD by Anonymous Coward · · Score: 0

    Nonsense! Name one accident with a rocket in the last 6 months!!

  23. A Windfall for Chemtrail Conspiracy Nuts by Ranbot · · Score: 1

    Speaking of efficient distribution... Now big government and big pharma can create and spread their mind-control chemicals and diseases around the world than from orbit! AMIRITE?!?!? The conspiracy theorist blogs and fake news sites are going to use this stuff for years!