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WHO Issues a List of 12 Most Worrying Drug-Resistant Bacteria (medicalxpress.com)

Artem Tashkinov quotes a report from Medical Xpress: The World Health Organization has issued a list of the top dozen bacteria most dangerous to humans, warning that doctors are fast running out of treatment options. WHO said the most-needed drugs are for germs that threaten hospitals, nursing homes and among patients who need ventilators or catheters. The agency said the dozen listed resistant bacteria are increasingly untreatable and can cause fatal infections; most typically strike people with weakened immune systems. At the top of WHO's list is Acinetobacter baumannii, a group of bacteria that cause a range of diseases from pneumonia to blood or wound infections. In recent years, health officials have detected a few patients resistant to colistin, the antibiotic of last resort. So far, doctors have been able to treat them with other drugs. But experts worry that the colistin-resistant bacteria will spread their properties to other bacteria already resistant to more commonly used antibiotics, creating germs that can't be killed by any known drugs.

91 comments

  1. Bacteria that worries by turkeydance · · Score: 0

    oy vey

    1. Re:Bacteria that worries by Anonymous Coward · · Score: 0

      In the meantime, wash your hands.

    2. Re:Bacteria that worries by slashrio · · Score: 5, Informative

      And please bring back the copper clads in the hospital, door plates, stairs, door knobs, bedsides, chairs etc.
      Copper kills bacteria, including the antibiotic-resistant ones, everybody knows that, except apparently the hospital staffs.
      Silver also, but that might be a bit too expensive.
      Dead bacteria can not be transferred to other people...

      --
      "Trump!!", the new Godwin.
    3. Re: Bacteria that worries by dougdonovan · · Score: 1

      just a thought to maybe call the bill and melinda gates foundation.

    4. Re:Bacteria that worries by Anonymous Coward · · Score: 0

      WHO Issues a List of 12 Most Worrying Drug-Resistant Bacteria

      I give up; who?

    5. Re: Bacteria that worries by gzuckier · · Score: 1

      Dr. Who, that's WHO.

      --
      Star Trek transporters are just 3d printers.
  2. 23,000 Die from Bacteria 250k Die from Malpractice by ZippyTheChicken · · Score: 0

    According to the U.S. Centers for Disease Control and Prevention, at least 23,000 people die each year in the U.S. from infections caused by resistant bacteria. The real problem is not bacteria... its incompetent medical practitioners Malpractice is now the 3rd leading cause of Death about 300,000 people die every year.. thats like someone nuked Miami and killed every man woman and child.. "People don't just die from heart attacks and bacteria, they die from system-wide failings and poorly coordinated care," says the study's lead author, Dr. Martin Makary, a professor of surgery and health policy at Johns Hopkins University School of Medicine. "It's medical care gone awry." The magnitude of the death toll – roughly 10 percent of U.S. deaths annually – is striking....

  3. This planet needs an enema by Anonymous Coward · · Score: 0

    Good ol fashioned war or disease should do it. That will help climate change.

  4. Re:23,000 Die from Bacteria 250k Die from Malpract by Anonymous Coward · · Score: 0

    I'd like to see the trendlines of these two statistics. Most probably, malpractice will exhibit some sort of linear or flat growth, whereas deaths attributed to resistant bacteria will exhibit an exponential growth.

  5. Re:Poor people in the US now have coverage.. by Anonymous Coward · · Score: 1

    The state of Washington is even more communist than California. It approaches European level.

  6. anti-bacteria hand sanitizes are bad by Anonymous Coward · · Score: 0

    anti-bacteria hand sanitizes will cause bacteria to morph into these super-bacteria which will kill us all.

    1. Re:anti-bacteria hand sanitizes are bad by slashrio · · Score: 1

      That's why I proposed copper.

      --
      "Trump!!", the new Godwin.
    2. Re:anti-bacteria hand sanitizes are bad by Michael+Woodhams · · Score: 2

      If they kill bacteria with antibiotics, yes. If they kill bacteria with alcohol (which is usually the case), then no, they are not bad and will not breed super-bacteria.

      --
      Quattuor res in hoc mundo sanctae sunt: libri, liberi, libertas et liberalitas.
  7. Drug of last resort by Anonymous Coward · · Score: 0

    If the drug of last resort didn't work, and then doctors used other drugs to fix the problem, sounds like "last resort" doesn't mean what they think it did.

    1. Re:Drug of last resort by Anonymous Coward · · Score: 0

      They used colistin before the other antibiotics. Colistin is an old drug that has some problematic side effects. This caused it to fall out of favor and it was rarely used, so the bacteria didn't develop resistance. My wife recently had an infection and the hospital cultured the bacteria before deciding on an antibiotic to treat the infection. Except they forgot to submit the sample in a timely fashion and she had to spend an extra day in the hospital before the antibiotic prescription was determined. They apparently felt that the cost extra day in the hospital was less than the consequences of the use of an ineffective antibiotic for a day. A little more complicated than that, but it's basically the story.

    2. Re:Drug of last resort by Imrik · · Score: 1

      They felt that the income from a justifiable extra day in the hospital combined with not having the consequences of ineffective antibiotics was to their benefit.

  8. Re:Poor people in the US now have coverage.. by Anonymous Coward · · Score: 0

    That's not true at all. Washington state only requires for less than 2/3 of vacation time to be paid-out. All of my Asian coworkers get to take two or more contiguous weeks off, since understandably flights to Asia are expensive and take a long time, but American workers aren't even allowed a long weekend. I've lost nine weeks and counting vacation time off since I was born in Tacoma, WA.

  9. Actual List by Anonymous Coward · · Score: 5, Informative

    Since the linked article is still a few clicks away from the actual list, which is then a PDF, here is the actual list:

    Priority 1: CRITICAL
    Acinetobacter baumannii, carbapenem-resistant
    Pseudomonas aeruginosa, carbapenem-resistant
    Enterobacteriaceae, carbapenem-resistant, 3rd generation cephalosporin-resistant

    Priority 2: HIGH
    Enterococcus faecium, vancomycin-resistant
    Staphylococcus aureus, methicillin-resistant, vancomycin intermediate and resistant
    Helicobacter pylori, clarithromycin-resistant
    Campylobacter, fluoroquinolone-resistant
    Salmonella spp., fluoroquinolone-resistant
    Neisseria gonorrhoeae, 3rd generation cephalosporin-resistant, fluoroquinolone-resistant

    Priority 3: MEDIUM
    Streptococcus pneumoniae, penicillin-non-susceptible
    Haemophilus influenzae, ampicillin-resistant
    Shigella spp., fluoroquinolone-resistant

    Source: http://www.who.int/medicines/p...

    1. Re:Actual List by thegarbz · · Score: 2

      This seems like one of those of cases where linking to the source really doesn't benefit the discussion.

      Sometimes abstracting helps understanding rather thanhindering it.

    2. Re:Actual List by david_thornley · · Score: 1

      I've actually had a couple of those. The Pseudomonas aeruginosa was treated successfully by levofloxcillin (sp?), and I went from insufficient blood pressure to keep my eyes functioning properly to feeling great in 10 days. The Staphylococcus aureus was treated with clindomycin (sp?), which works great, in addition to giving my intestines inspiration to try new and innovative things to do something I had already thought worked satisfactorily. So far, so good.

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
  10. Shit by Anonymous Coward · · Score: 0

    I think natural selection is about to kick our ass. Although I guess an upside is in a few generations the remaining humans may have a natural defense for it.

    Crossing my fingers that they can create some kind of bacteriophage to replace all these failing medications and fight off the bacteria that way.... or anything else they can come up with.

  11. Re: Poor people in the US now have coverage.. by Anonymous Coward · · Score: 0

    Doctors don't get paid unless their ratings are high enough. That's why they won't give us antibiotics, but give them out like candy to ObamaCare recipients.

  12. Is resistance built to iodine? by Anonymous Coward · · Score: 0

    It is common knowledge that this was used widely in hospitals for decades, and supposedly(?) resistance is not built up to it.

    1. Re:Is resistance built to iodine? by Anonymous Coward · · Score: 0

      It is common knowledge that this was used widely in hospitals for decades, and supposedly(?) resistance is not built up to it.

      It's a topical antibiotic. It works the same way that Clorox does in killing germs.
      It won't help for pneumonia, strep throat, staph and so on when they get inside your lungs, bold, etc.
      That is, in doses that you could survive.

  13. The story is: we create these bacteria by using an by Anonymous Coward · · Score: 0

    Scientists examine bacterium found 1,000 feet underground Resistant to 18 different antibiotics
    Maybe we aren't the cause of all these terrible things we think we found...
    Human nature. You could sacrificed a goat to the Earth Goddess, do a dance around the fire while beating on a drum... toss in some flaguation and repent your sins; and you will feel fine.

  14. Disabling advertising on Slashdot by Anonymous Coward · · Score: 1

    A long time slashdot user, I have been offered the opportunity to disable ads in the sidebar on the classic.slashdot.org main page, but wanting to support the site I never disabled it.

    Recently however there have been annoying ads that stay "stickied" on top even when you scroll down and it has been driving me nuts, so finally I decided to use the option. Except it has disappeared! What happened? Does the option only appear under certain circumstances? Did the new overlords remove it and I simply missed my chance?

    1. Re:Disabling advertising on Slashdot by Anonymous Coward · · Score: 0

      Oh wow, are you thread-jacking? Are you going off topic? Are you looking for tech support?

    2. Re: Disabling advertising on Slashdot by Anonymous Coward · · Score: 0

      I am looking for tech support. This fucking samsung 4k bluray player isnt working right. Can you help?

    3. Re:Disabling advertising on Slashdot by Anonymous Coward · · Score: 0

      Sure, not like anything more interesting is going on here

    4. Re: Disabling advertising on Slashdot by Anonymous Coward · · Score: 0
  15. Re: 23,000 Die from Bacteria 250k Die from Malprac by Anonymous Coward · · Score: 0

    I support efforts to nuke every man, woman and child in Miami.

    And just to prove chilvalry isnt dead... i hope the women and children die first.

  16. So-called "drug-resistant bacteria" by PopeRatzo · · Score: 3, Funny

    The president says he's going to get us out of WHO, so problem solved.

    --
    You are welcome on my lawn.
  17. So what's the answer? by easyTree · · Score: 1

    Maybe genetically engineering a meta-virus which will modify those in the wild?

  18. Re: 23,000 Die from Bacteria 250k Die from Malprac by ZippyTheChicken · · Score: 0

    Bad Spring Break Experience? heh

  19. WTF ads over whole screen??? by Anonymous Coward · · Score: 1

    Hi I've never flamed on Slashdot but about 60% of my browser screen is ads. The top 40% and the right 20%. This is intolerable, so even though my "karma" is excellent and my signup number is low seven figures, I'm outtahere.

  20. But iodine is restricted due to the drug war. by Ungrounded+Lightning · · Score: 1

    It is common knowledge that [iodine] was used widely in hospitals for decades, and supposedly(?) resistance is not built up to it.

    But iodine, and most iodine-containing medical preparations, are heavily restricted, due to the drug war.

    Seems they're used in one step of turning pseudephedrine into meth. So, though they're not actually BANNED, the drug warriors put so much red tape on them that most chain-store drug stores just dropped them as unprofitable.

    (I found this out when the fallout from Fukishima was approaching the US west coast, and I tried to find some iodine supplements for my family to dose up on, to reduce the risk from radioiodine, before it got here. Surprise! None to be had.)

    If anybody knows of a chain store in California or Nevada where I can buy potassium iodide supplements or tincture of iodine, over the counter, please let me know.

    --
    Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
  21. Re: Poor people in the US now have coverage.. by Anonymous Coward · · Score: 0

    I have a high deductible plan. My deductible for prescriptions is $1300. Most newer antibiotics arent even covered. If you need more than penicillin you are pretty much fucked unless you have a lot of cash on hand. Between the doctor and Rx costs, if i need anything prescribed I order it from mexico. Its cheaper.

    Likewise i have some friends on medicaid. They use the emergency room as a primary care provider and are in and out like a revolving door. Every time their kids get the sniffles its off to the ER for another z pack. One girl in particular, with two normal healthy kids... she probably goes to the ER at least 200 times a year. Never pays a cent.

  22. Re: The poor in the US get ObamaCare... by easyTree · · Score: 1

    Welcome to healthcare as practiced in civilised countries. It's probably quite a shock.

    Meta-comment: stating uncomfortable truths != trolling.

  23. Re:23,000 Die from Bacteria 250k Die from Malpract by XXongo · · Score: 5, Insightful
    Uh, what the fuck does your libertarian rant have to do with Obamacare?

    A properly administered free-market system that allows insurers to cross state lines and removes a lot of the useless regulatory BS that makes practitioners hesitant to treat people will save tens, possibly hundreds of thousands of people who will otherwise die thanks to the Obamacare act.

    Bullshit. Pure, unmitigated bullshit. America has the most expensive healthcare system in the world. Here's a clue for the clueless: it's not because of government regulation, and it was the most expensive in the world (and one of the worst) even before Obama was elected. The "socialist" healthcare systems of Europe are both cheaper and also better. Yeah, libertarianism works great --when you've never been outside your basement.

    Here's what laissez-faire capitalist healthcare really looks like: the health care conglomerates soak sick people for all they can take, because sick people don't have the resources to bargain. Then, when they run out of money, you let them die. For the conglomerates, it's like a money spigot.

    For the sick people, of course, it's a death trap with the added feature that it bankrupts you, too.

  24. Re: The poor in the US get ObamaCare... by Anonymous Coward · · Score: 0

    I had a couple illegals run a red light and tbone me. And theyre suing me for $5 million. No injuries. But they get medicaid and went to the doctor 108 times since the accident, and counting. Pulled up the court records and they get into these "accidents" every 2 years. It is so nice when the system works. I wish i had that kind of coverage.

  25. Time to restart using antisera. by Ungrounded+Lightning · · Score: 2

    Before antibiotics one could get an antiserum against each of many nasty infections. The rise of antibiotics displaced these drugs - even for some things (such as some forms of meningitis) where an antiserum against the particular organism, did a better job.

    This actually made some sense. Antibiotics were broader spectrum, so (even after drug resistant bugs became common) you were likely to find one that worked in time to save the patient. Antisera, on the other hand, were very bug-specific.

    If multiple drug resistance makes antibiotics nearly useless, perhaps it's time to revive antiserum use.

    We now have the technology to rapidly identify the target organism(s) in a disease process, so we can rapidly select the correct magic bullets. And we also have the technology to make specific antisera by the bucketful.

    And without the side-effects of making it by exposing an animal (like a "serum horse") to a pathogen and then (once it's developed an immunity) extracting the (horse-type) antibodies to this - and to everything else its immune system doesn't like - to make the drug. Instead we can make human monoclonal antibodies to just one target.

    We can also engineer an immunization by chopping out the DNA for some conserved region snippet of some pathogen's accessible surface markers, splicing it with neighboring coding that will make the immune system take note and building it into an otherwise (and still) harmless bug - either to make an active ingredient for an immunization cocktail or a variola/polio style live-virus challenge. The bug has a very hard time evolving resistance because a conserved region of some component of its molecular machinery is usually conserved because has to be the way it is for it to work.

    This is already being done to some extent. Seems to me it's time to stop crying about the end of antibiotics and focus on this set of approaches - which should be very lasting.

    --
    Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
    1. Re:Time to restart using antisera. by del_diablo · · Score: 1

      Maybe. But that just begs the question, that a layman would ask: How is antiserum different from vaccination?

    2. Re:Time to restart using antisera. by Ungrounded+Lightning · · Score: 1

      How is antiserum different from vaccination?

      Four things:
      - Immunization
      - Innoculation
      - Vaccination
      - Antiserum

      An immunization is a challenge to the immune system that looks to it like the target pathogen - often with an adjuvant to do enough minor mischief to convince the immune system that this is a really bad guy that needs a SWAT team response. It might be made out of:
      - pieces of killed pathogen,
      - pieces of killed related pathogen,
      - engineered molecules similar to a target site on the ,
      - live related pathogen (enough like the bad guy to provoke a cross-reaction to the bad guy, but not enough like the bad guy to cause the disease),
      - live attenuated pathogen (an artificially weakened version of the actual disease - essentially an engineered "live related pathogen"
      - the actual, full-bore, pathogen itself - but administered in a way that leads to a less severe (i.e. survivable) case of the disease,
      etc.

      The immune system has an enormous number of small clones (just a handful of cells) that each produce a different antibody (and can produce one or more of several types of response against a pathogen), and essentially any that produce antibodies against the body itself have already been killed off. When the body signals "I'm being attacked", by either a disease or an imunization (which mimic a disease) those that recognize the antigen go into rapid reproduction, and a fraction differentiate into active forms. This takes about three days - but after that you have a LARGE number of mature immune cells that attack that pathogen, along with a boosted number of not-yet-matured "memory cells". This doesn't stop an original infection. But it cleans up after it, and blocks (or mitigates) future infections by attacking the pathogen as soon as it shows up. If you get another case of the disease - or a booster shot - the memory cells will repeat the process, making the immunity much stronger.

      Vaccination is a particular case of a "live related pathogen": One of the (closely related) cowpox or vaccinia viruses, somewhat more distant relatives of smallpox, is used to create a minor infection (generally one scarring pimple, unless you scratch and spread it). This activates the person's immune system against both the vaccine's virus and its relatives, including smallpox.

      The Sabin "live virus" polio vaccine works the same way, using a weaker, mutated, version of the polio virus. (Its predecessor, the Salk vaccine, uses the outer coat of killed polio virus.) A live virus actually produces a disease process lasting several days, until the immune system clears it up. This creates a stronger and longer lasting immunity than a simple challenge with dead virus pieces. (It also is contagious: Some people who weren't administered the immunization "catch" the "fake disease" from those who recently were immunized.)

      Inoculation consists of deliberately administering the pathogen. In the case of a disease, it means causing the disease, in a way that can be treated or is otherwise is survivable, leaving the recovered person immune. Before vaccination, inoculation was used for Smallpox. If you catch smallpox by inhaling the virus, you're likely to have a severe case, either dying or maybe being horribly scarred. If you catch it by having some pus from an infected person get into a cut in your skin, you're likely to have a mild case, with only localized scarring, and then (as a survivor) be immune. (Unfortunately, while you have the case, you're infectious with the disease, so others can catch it the bad way. That's the biggest reason that vaccination was such a drastic improvement.)

      Unfortunately, immunizations are usually too late to protect you against a disease you already have. (A notable exception is rabies, which works its way slowly up the nerves to the brain, giving time to immunize before it becomes acute, incurable, and fatal.) An antiserum works imm

      --
      Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
  26. We did it! by Gravis+Zero · · Score: 1

    Despite all the pesky warning and regulations preventing this very situation, we managed to get around all of it and create the most dangerous bacteria that human-kind has ever seen! Everyone, give yourselves a pat on the back because we earned this. I hope you all got biohazard suits so you can safely watch humanity get ravaged by our new little "friends"! ;)

    --
    Anons need not reply. Questions end with a question mark.
  27. Sodium Chlorite by Anonymous Coward · · Score: 0

    How does MMS fair against these bacteria?

    1. Re:Sodium Chlorite by Michael+Woodhams · · Score: 2

      If the bacteria are outside of a person, bleach does an excellent job of killing them.
      If a person with bacteria takes bleach, it does an excellent job of killing them.

      --
      Quattuor res in hoc mundo sanctae sunt: libri, liberi, libertas et liberalitas.
    2. Re: Sodium Chlorite by Anonymous Coward · · Score: 0

      The funny thing is...after being infected by an un-named hospital and repeatedly re-admitted for another course of vancomycin IV for a week, then a 2 week course of oral vancomycin; I became frustrated to the point that I would try anything. The MMS protocol, at the proper dilution, using this diluted mixture, one drop activated with one drop of citric acid in a glass of apple juice daily. Each day I increased the dosage by one drop. At the end of 6 weeks my tolerance to the MMS allowed me to take 15 drops of MMS (diluted of course) activated by 15 drops of citric acid. I took 2 doses of this 1 hour apart. This was continued for 2 weeks. Since then, the infection has not returned. I suggest you read Jim Humble's book and / or watch his interview. 100% NaClO2 is used to sterilize operating rooms. The concentration in MMS is around 28% and then only one drop, activated by citric acid and then diluted again in a glass of apple juice is used. The fact that MMS is not profitable to the pharmaceutical industry says a lot about what they think of you, you are a return customer to be used until you are dead. NEXT!

  28. Who issues a list ... by Anonymous Coward · · Score: 0

    I give up who?

  29. Re:23,000 Die from Bacteria 250k Die from Malpract by slashrio · · Score: 1

    As if this wasn't already the case before Obamacare.
    Off-topic!

    --
    "Trump!!", the new Godwin.
  30. Re:23,000 Die from Bacteria 250k Die from Malpract by slashrio · · Score: 2

    For the sick people, of course, it's a death trap...

    And if you're not sick already, then beware!
    Official marketing target of the pharmaceutical companies: Each person on earth 2 medications daily.
    And they're not so ethical as to shun away from committing hidden crimes against humanity to reach that goal.

    --
    "Trump!!", the new Godwin.
  31. Re:23,000 Die from Bacteria 250k Die from Malpract by Anonymous Coward · · Score: 0

    Notice that the only people complaining about the NHS in the UK are their local kleptocratic class and American libertarians who only stop posing long enough to pick up their disability check.

  32. Walgreens lists it as in stock by raymorris · · Score: 1

    > If anybody knows of a chain store in California or Nevada where I can buy potassium iodide supplements or tincture of iodine, over the counter, please let me know.

    The very first place I tried was Walgreens. You didn't say what part of California, so at random I checked availability in San Francisco. Here's one brand:

    https://www.walgreens.com/stor...

    Of course Amazon will deliver it right to your door.

    Your difficulty finding it may indeed have something to do with illegal drugs. Not quite in the way you were thinking, it seems.

  33. mod parent up by Anonymous Coward · · Score: 0

    cutting through the click bait is a community service

  34. Re:23,000 Die from Bacteria 250k Die from Malpract by Anonymous Coward · · Score: 0

    This illustrates numerically the very steep cost of Obamacare in human lives. Too often we get caught up in the dollars and cents arguments, and miss the bigger issue of the fact that the healthcare act is killing people left and right. A properly administered free-market system that allows insurers to cross state lines and removes a lot of the useless regulatory BS that makes practitioners hesitant to treat people will save tens, possibly hundreds of thousands of people who will otherwise die thanks to the Obamacare act.

    Ignoramus. The 250K lost lives number long predates Obamacare.
    Absolutely nothing has changed in American healthcare since Obamacare was implemented.

  35. Re:Poor people in the US now have coverage.. by Anonymous Coward · · Score: 0

    Considering that you can get free or near zero cost antibiotics in the USA without any coverage at all, I'd say your friends are bragging about being morons.

  36. Targeted Alpha Therapy offers a solution by KonoWatakushi · · Score: 2, Informative

    For some time, Targeted alpha therapy has shown promise for treating difficult cancers, but it may also be used to kill antibiotic-resistant bacteria and pathogens like HIV. Once this capability is developed, the antibiotic arms race will end once and for all. The looming threat is very serious, and such promising research should be a high priority.

    Unfortunately, there are artificial barriers that are retarding progress. The most attractive isotopes for use with TAT are Actinium-225 and Bismuth-213, which no longer exist in nature. Looking at the periodic table, one might be inclined to believe that other substitutes exist, but they simply don’t. The neptunium decay chain is unique in that it does not pass through radon or terminate in lead. Born in supernovae long ago, it was extinct in nature until relatively recently, when it was revived in the heart of nuclear reactors.

    However, conventional reactors don’t produce much, and it is impractical to extract the short-lived isotopes from solid fuel rods sealed in a reactor core. Liquid Fluoride Thorium Reactors however, are the ideal machines for producing these life-saving medical isotopes. Meanwhile, LFTR safely transforms nuclear waste into abundant and inexpensive energy.

    It is worth noting that Flibe Energy is the only company in the west pursuing this technology; others developing molten salt reactors are trying to take shortcuts which miss out on the greatest benefits of the thorium fuel cycle. LFTR is a comprehensive solution, which can finally close the fuel cycle, eliminating the need for uranium mining and enrichment. It is a more challenging design, but it doesn’t kick the can down the road; it fully addresses all rational concerns with nuclear technology, and offers many new opportunities.

    1. Re:Targeted Alpha Therapy offers a solution by david_thornley · · Score: 1

      How do you apply the radioactives to the bacteria without irradiating the patient?

      --
      "When you have eliminated the unacceptable, whatever is left, however improbable, must be the truthiness" - Holmes
    2. Re:Targeted Alpha Therapy offers a solution by Anonymous Coward · · Score: 0

      I am not a biologist and can't go into detail, but the idea is that the isotopes are attached to antibodies, which then seek out the target. This is especially attractive for dispersed cancers which can't be targeted by conventional means, or other difficult to kill pathogens. The alpha particles emitted will destroy the immediate cells, but have very little penetrating power and can be stopped by a sheet of paper. Some will miss the target, but very little material is required, so collateral damage will be limited.

      Humans evolved in a naturally radioactive environment, and there are repair mechanisms constantly fixing radiation damage, and much more common chemical/oxidative damage. The key is not overwhelming those mechanisms, and the large doses used for irradiating solid cancers with traditional therapies give an appreciation for just how effective they are. Unfortunately, the burdensome LNT regulations in place are based on the idea of cumulative dose, which is pure fiction, yet largely responsible for the pervasive fear surrounding radiation.

  37. Re: The poor in the US get ObamaCare... by Anonymous Coward · · Score: 0

    Apparently you can. I suggest cutting the safety belt and installing a harness first.

  38. who by prof_robinson · · Score: 0

    "So WHO issues a list of 12 most worrying drug-resistant bacteria the other day..."
    "Really? Drug resistant bacteria?"
    "Yep."
    "Who released it?"
    "WHO did."
    "That's what I asked, who released it?"
    "The bacteria?"
    "No, the list. Who released it?"
    "Exactly."

    c'mon guys...it writes itself....

  39. Colistin Misuse by Anonymous Coward · · Score: 0

    In some countries, colistin is used in veterinary practice. Better cook your pork and beef properly.

  40. And yet still used as cattle feed by dargaud · · Score: 2

    No matter how many studies about antibiotics resistance, still in the US they keep on feeding antibiotics to cattle to make them grow slightly faster to make slightly more money. All this at the long term risk of killing most of us. No, that's not hyperbole: before the invention of antibiotics, one skin infection out of 9 was deadly. Yes, a bit of pus in a scrape, deadly one time out of 9, let that soak in (the idea, not the pus).

    I remember a discussion about that here on ./ a decade ago where a moron was defending this feeding, saying "no studies have shown any risk". Then a few years later some studies started tracing out the DNA origin of some resistances and pinpointed them to some US industrial farms, I wanted to find our exchange of posts and rub it in "told you so", but ./ message search sucks ass and I could never find them.

    --
    Non-Linux Penguins ?
    1. Re:And yet still used as cattle feed by thegarbz · · Score: 1

      Even if you could find them discussions are archived so it wouldn't allow you to reply.

    2. Re:And yet still used as cattle feed by tomhath · · Score: 1

      The drugs used by livestock feeders aren't the same ones that worry WHO.

      You're spreading fud; these antibiotic resistant bacteria are caused by inappropriate use of antibiotics to treat humans, mostly (but not entirely) in Third World countries.

    3. Re:And yet still used as cattle feed by Pinky's+Brain · · Score: 1

      Any drug formerly effective against any of the bacteria on their list worry the WHO by no longer being effective. Just because they mention only one of the best broad spectrum anti-biotics which they are resistant against doesn't mean those drugs are the only relevant ones. Since someone mentioned colistin was used on animals I did a quick google, Salmonella is on the list and colistin resistance is spreading. By complete coincidence it's used in agriculture for Salmonella infections.

      Even more so though, the drug they do mention for Salmonella, fluoroquinolone, was in fact widely used in agriculture ... and still is, illegally.

      Stop rationalizing the shit you have to do to make your farming economical. Doing it is one thing, but don't lie to yourself and others about it.

    4. Re:And yet still used as cattle feed by starblazer · · Score: 1

      but, uneducated opinion here, wouldn't any hint of antibiotic slightly related to the pathogen strengthen any bacteria against it? you know, that whole theory of "whatever doesn't kill you makes you stronger?"... or does that not apply to the microbiology world?

    5. Re:And yet still used as cattle feed by slew · · Score: 1

      but, uneducated opinion here, wouldn't any hint of antibiotic slightly related to the pathogen strengthen any bacteria against it?

      you know, that whole theory of "whatever doesn't kill you makes you stronger?"... or does that not apply to the microbiology world?

      In the microbiology world, whatever doesn't kill you, but weakens or kills your competitors, makes your progeny (and your resistance) more prevalent. So in the metagenetic sense it makes your germ-line stronger, but it doesn't do much for you specifically (except get rid of your competition).

    6. Re:And yet still used as cattle feed by dargaud · · Score: 1

      I know that, but a direct message or, better, a public shaming in a new discussion such as this one. This is too important. Antibiotics shouldn't be given as animal food, and I'm beginning to think that they shouldn't be given to animals at all, period.

      --
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  41. Re: 23,000 Die from Bacteria 250k Die from Malprac by Anonymous Coward · · Score: 5, Interesting

    I'm a Brit (on disability welfare myself actually), and I'm pretty sure I'd be dead without socialised healthcare. Which, also, has fuck all to do with the quality of healthcare available. If you want shorter waiting times for non-critical conditions (the ones that require something fancy like major surgery but that you can easily survive a few months or so waiting for), doctors more willing to try very expensive and not very successful treatments etc, nothing stops you from having private health insurance and seeing private doctors, if you can afford it. The only difference is that if you can't afford it, you still have access to free, high quality healthcare. I've never understood this argument - it's not like having socialised healthcare makes private healthcare illegal.

  42. Re: 23,000 Die from Bacteria 250k Die from Malprac by Anonymous Coward · · Score: 3, Interesting

    Spot on. I'm a Brit too and would be quite happy spending my whole life paying into the NHS without ever having to use it.

    The American system where you can get hit with a disease, or have an accident, and then die because you can't afford the treatment is barbaric and medieval.

  43. Re:23,000 Die from Bacteria 250k Die from Malpract by moeinvt · · Score: 2

    "America has the most expensive healthcare system in the world"
    "Yeah, libertarianism works great ..."

    Libertarianism? In the USA healthcare system? LMFAO.

    Where exactly do Medicare, Medicaid, Obamacare, bans on free trade of prescription drugs and the tons of other government regulations fit into your definition of "libertarianism"?

    In 2016, the federal government spent over $900 BILLION on Medicare, Medicaid, Obamacare subsidies and other socialized healthcare programs. Due to federal government regulation, prescription drug in the USA can cost 5x, 10x, 20x ... as much as the exact same drug in Canada, Mexico or other countries. Removing that federal ban would save us tens of billions of dollars at minimum. Mandates on insurance policies prevent people from buying the exact coverage they want. Medicare & Medicaid price controls force providers to shift costs onto the privately insured & absolutely rape the working uninsured.

    The U.S. Government has been heavily involved in the healthcare system for over 50 years! What are the results of their interventions? Skyrocketing prices, millions unable to afford basic services & quality which, as you noted, lags behind other countries.

    Are there ANY other goods or services which, over that same time period, have experienced such ridiculous price increases for such lackluster quality(except housing and higher ed, which are also big government clusterfucks) Hell no! Even medical-related services like Lasik eye surgery have become better and cheaper.

    Innovation & competition bring down prices. Government intervention has the opposite effect.

  44. Re:23,000 Die from Bacteria 250k Die from Malpract by Anonymous Coward · · Score: 0

    Umm... One of the biggest problems is the use of antibiotics in bio-industry and farming.
    Some antibiotics are known to stimulate growth, and others are used to keep animals in less clean conditions to lower cost.
    Those antibiotics remain resident in the meat, and can cause resistance in people eating that meat.
    In Europe they try to regulate that, but there are criminal cartels that are selling that stuff. Those criminals even threaten and murdered animal doctors whom tried to report that.

    Yes - misuse of antibiotics for curing people is prominent, but misuse in bio-industry and farming is far more serious...

  45. Moderated Troll, really? by KonoWatakushi · · Score: 1

    Someone can't accept new nuclear, even to save their own life. Chances are very good that you or someone close to you will die from cancer someday, which could have been preventable if ideology didn't blind you. If the fools in government weren't more interested in weapons than energy, this technology would be saving countless lives today, and inexpensive carbon-free energy would be the norm. There is a good article detailing the specifics and history of LFTR for those with a mind open to facts.

    The crusade by some to eliminate nuclear above all else will mean missing carbon targets if successful. Respected climate scientists like James Hansen agree that we can't afford to dismiss nuclear. Those working to obstruct nuclear progress also ensure that first generation reactors remain in service far longer than necessary.

  46. Re:23,000 Die from Bacteria 250k Die from Malpract by cyberchondriac · · Score: 1

    And all Obamacare did was put a band-aid over it. Instead of addressing the real issues, like why medicines, surgeries, and hospitals are so damn expensive, and why malpractice is (ostensibly) rampant, it just shifted how the costs are paid. For some people, it was a boon, for others, it made their situation worse. It was rushed into law without proper debate and revision.

    --

    Look back up at my post, now look back down, you're on the Internet. Now look back up. I'm a signature.
  47. Brass is likely more practical. by emil · · Score: 2

    It's just as toxic, and it has better corrosion resistance.

    Note to hospitals: the oligodynamic effect is your friend - please start relying upon it!

    1. Re:Brass is likely more practical. by slashrio · · Score: 1

      Ok, brass then, it's even cheaper.

      --
      "Trump!!", the new Godwin.
  48. FUD? FUD?! by Anonymous Coward · · Score: 0

    I see you are a purveyor of so-called "alternative facts".

    Prophylactic use of antibiotics is always a concern. Any microbiologist can tell you that; any infection prevention and control clinician can tell you that. Resistance mechanisms can develop, be shared and swapped, and the exact antibiotic involved is hardly the point.

    Likewise, blaming Third World countries. Even if that's true, so what? People die in the developed world of antibiotic resistance; it doesn't matter where in the world the resistance genes flourished. It only matters that the dying person has an infection their body cannot fight off and doctors cannot help.

    Yet it's still bogus blaming the Third World. There are plenty of intensive agricultural operations on-shore that use or used antibiotics in feed. The justification is that the animals put on weight faster and there are fewer deaths in the herd. Thus, money talks. The motivations for doing this are pretty easy to understand especially when the person paying the price for the fatter, larger herd, is an unrelated dying person hundreds or thousands of kilometers away.

  49. Asian Seafood and antibiotics by FrigBot · · Score: 1

    Bloomberg Businessweek a few months ago did an article based on research that found use of heavy duty antibiotics in seafood (mostly shrimp) farming in China. Drugs like colistin are being used. The article talked about how waste from pig farming is somehow used to feed the farmed shrimp. Improting "food" like this into the States is obviously illegal. To add insult to injury, there are shell companies in China, Thailand, etc. set up for the sole purpose of circumventing those legal controls, and the shrimp ends up in North American grocery stores and restaurants. It speculated that perhaps there are these super bad bacteria coming over with them.

  50. Re:23,000 Die from Bacteria 250k Die from Malpract by Anonymous Coward · · Score: 0

    The U.S. Government has been heavily involved in the healthcare system for over 50 years! What are the results of their interventions? Skyrocketing prices, millions unable to afford basic services & quality which, as you noted, lags behind other countries.

    Well over 50 years. Considering tax incentives to promote employer-paid healthcare (bad idea, ties you to your job, doesn't increase your compensation just shifts it around - can't start a competing business with your salary, got to pay for your healthcare).

    I don't remember when that started but - IIRC - it was because wages were frozen (thanks Obama!) and one loophole was health insurance. So instead of a raise, you got coverage. This one perverse incentive combined with reinforcement (individuals are comparatively penalized to buy their own - after-tax dollars) is a large part of why where here today. This was 1940s or 50s.

    Of greater concern is the drug war which is likely late 1800s/early 1900s stuff. Now we can't import stuff that Brits, Canadians, Mexicans, Chinese or whoelse might take advantage of.

    Of greater concern still is the AMA. This might be early 1800s stuff and more state-government related. They shut down black medical colleges and that practice, limited supply. All with government-gun backed force. A large part of the AMA's rise was the anti-abortion movement. Midwives and moon-tea peddlers were competition that needed to be snuffed out.

    Government has been fucking up healthcare even when ink was practically still wet on the US Constitution. GPPPP poster's rant against libertarianism is simply an indication of either intellectual dishonest or a fucking retard. The liberty option has been off the table for over 200 years.

  51. Re: 23,000 Die from Bacteria 250k Die from Malprac by gzuckier · · Score: 1

    System wide failings and uncoordinated care are not malpractice in the conventional sense, unless you want to consider it malpractice on the part of civilized society. In fact, this rise of drug resistant bacteria can be considered a subset of those system wide failings and uncoordinated care.

    --
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  52. Why dont they get rid of BUILDING??? by syntotic · · Score: 1

    Easy solution, use temporal discardable pavilions for specific patients and treatments. Should be easy to design. Unless, of course, there IS some psychosis strain that gets a kick from thinking people infected and unable to do anything, subject to the elements and State of Nature again, without choices and overwhelmed, entertained in its own gross infections and diseases development and doctors subscribing the ideology for these clients...

  53. Re: 23,000 Die from Bacteria 250k Die from Malprac by gzuckier · · Score: 1

    But Medicare is the part of the US medical system that works best, by objective quantitative measures. Lowest costs, and best outcomes compared to other countries. Not just comparable outcomes; if you make it to Medicare age in the US, your life expectancy becomes highest in the developed world. That's Medicare, you know, the single payer government socialized universal health program.

    --
    Star Trek transporters are just 3d printers.