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Belgian Scientists Inhibit Protein Responsible For Allergic Reactions (ugent.be)
lhunath writes: Scientists at the University of Gent exposed the TSLP protein's function in triggering allergic reactions such as asthma and eczema. The team then developed a protein-based inhibitor used to capture TSLP and prevent its bioactivity as it associates with its natural receptors. Using this method, allergic reactions can be inhibited before they are triggered.
The team's results were recently published in Nature, where they share a vision that their work "will guide therapeutic approaches that manipulate human TSLP-mediated signalling to treat allergic diseases."
The team's results were recently published in Nature, where they share a vision that their work "will guide therapeutic approaches that manipulate human TSLP-mediated signalling to treat allergic diseases."
It was discovered by a university, not a commercial drug lab. Either way, this is nothing to sneeze at.
"Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
This doesn't sound like a cure so much as a treatment. That one has to take on a regular basis. For the rest of one's life.
Should a product come to market, most healthplans won't cover it for most cases, only the most severe relevant allergic reactions that have strong chance in resulting in death of the patient would be covered. Expect a rise in the number of Athsma diagnoses.
Do not look into laser with remaining eye.
I'm itching to give it a try.
You are welcome on my lawn.
Nah, it looks like it will be a monoclonal antibody, so only around $10,000 per monthly infusion. That's the going rate for drugs that end in "umab" which is apparently latin for 'expensive'.
Anyway, thanks for the real link, editors.
Faster! Faster! Faster would be better!
Nope. Survival of the fittest will always be the rule. It just happens that, at this point in time, 'fittest' means those humans closely attached to a complex, highly developed society that can make 747's, moon rockets and wildly complex drugs have a distinct advantage over previous humans and those unfortunates that live in New Jersey.
This may change at some point in the future.....
Faster! Faster! Faster would be better!
Efforts to get at the root cause of allergies are exciting, and pose the possibility of treatment with fewer or no side effects (an improvement), more effective treatment (and improvement) or even a cure (massive improvement). Yet most of the comments are inane observations about how "fragile" humans are(so should we just stop researching diseases and disorders then?), "now what?" (there will be more research and hopefully practical results!), or about the massive expense, or another tiresome variation of how "this isn't news or doesn't belong on slashdot". Slashdot's community used to be insightful and fun. Now you're more likely to see knowledgeable comments and wit over on reddit. Slashdot seems to have become a refuge for aging techies with a naive libertarian view of the world, an irrational hatred of "sjw's", and a general cynicism. What a waste of what was once a fun place to get news for nerds and read comments that ADDED to the news.
And you know this how, exactly?
And you know this how, exactly?
"I do not agree with what you say, but I will defend to the death your right to say it"
This won't prevent all allergic responses. We've carried out research that indicates there are at least two types of allergic responses, one TSLP-dependent and another Interferon alpha-dependent:
https://growkudos.com/publicat...
The TSLP response seems to be most associated with chemical-related irritants (e.g. cinnamon oil, SLS), while the IFN-a response seems to be most associated with small organism irritants (e.g. house dust mites, parasites).
Ask me about repetitive DNA
So, the same as Purdue with Oxycontin ... public research and expenses, private profits.
"Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
I am not on this study but it is a close colleague of mine (in the same lab) that has made the TSLP trap. It is NOT an antibody. Basically, he fused the extracellular parts of the receptor and the co-receptor into a single fusion protein, which binds TSLP very efficiently and does not release it for a very long time. This recombinant protein can be produced in large quantities, so the production costs will especially depend on the manufacturing standards for biologicals The "golden standard" benchmark that they compare their fusion protein TSLP trap with is an antibody though.
I hope I'm not making a rash decision by joining this thread.
Escher was the first MC and Giger invented the HR department.