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E-cigarettes 'Potentially As Harmful As Tobacco Cigarettes' (uconn.edu)

An anonymous reader shares a report: A study by chemists at the University of Connecticut offers new evidence that electronic cigarettes, or e-cigarettes, are potentially as harmful as tobacco cigarettes. Using a new low-cost, 3-D printed testing device, UConn researchers found that e-cigarettes loaded with a nicotine-based liquid are potentially as harmful as unfiltered cigarettes when it comes to causing DNA damage. The researchers also found that vapor from non-nicotine e-cigarettes caused as much DNA damage as filtered cigarettes, possibly due to the many chemical additives present in e-cigarette vapors. Cellular mutations caused by DNA damage can lead to cancer.

30 of 362 comments (clear)

  1. I don't believe that but... by Chris+Mattern · · Score: 3, Interesting

    E-Cigarettes don't have any tar, which is truly nasty stuff, and that makes them better than tobacco. But I am willing to believe that they are bad for you. Nicotine is fairly nasty (and highly addictive) on its own.

    1. Re:I don't believe that but... by Talderas · · Score: 5, Insightful

      The study was only looking at cancer risks so drawing conclusions that vaping is just as bad as smoking from this article is ill informed. As you allude to there are other respiratory illnesses, like COPD, where the tar from smoking is a major factor. If vaping has equivalent odds of causing cancer as smoking but reduces risk of other illnesses it seems rather obvious that we should encourage people to move from smoking to vaping in order to reduce the amount of respiratory illness. Getting them off smoking/vaping entirely would be the best but addictions are what they are.

      --
      "Lack of speed can be overcome. In the worst case by patience." --Znork
    2. Re:I don't believe that but... by UnknowingFool · · Score: 4, Interesting

      I would say the conclusion would be that just because there is no tar does not mean that e-cigs are not harmful. There are dangers with e-cigs. They happen to be different dangers than cigarettes.

      --
      Well, there's spam egg sausage and spam, that's not got much spam in it.
  2. What about... by irving47 · · Score: 4, Funny

    I have to wonder if the simpler non-nicotine versions are anywhere near as harmful. Food-grade vegetable glycerine and peppermint oil just don't scream, "I am chemical death" to me, but what do I know.

    --
    I had a sucky sig.
  3. It's not easy to quit by Lucas123 · · Score: 3, Insightful

    But it's the best thing you'll ever do for your health, and to not be beholden to a drug is a remarkably freeing feeling.

    1. Re:It's not easy to quit by ArchieBunker · · Score: 4, Insightful

      I work with a woman who smoked for 20 years. She told me quitting cold turkey was fine and people are babies about it.

      --
      Only the State obtains its revenue by coercion. - Murray Rothbard
    2. Re:It's not easy to quit by Lucas123 · · Score: 4, Interesting

      For some it is easy, for others it's harder than quitting an addiction like alcohol or opioids. (Source: I've worked in homeless shelters and talked to addicts about it).

      For me, it was easy the first time to go cold turkey. I was 17 and I'd been smoking for three years. When I started smoking again 18 years later and then quit three years after that, it was really difficult. The nicotine had really taken hold for some reason the second time. I finally turned to Nicorette gum, and in that moment when I popped that little cube in my mouth and the craving just dissipated, I realized I'd been a drug addict.

      Been smoke free for nearly 20 years, and it's definitely the best decision from a health standpoint I've ever made.

  4. Re: Drug delivery device by slazzy · · Score: 5, Informative

    While nicotine is a dangerous chemical poison (and useful insecticide) I was always under the impression it was other chemicals in cigarettes that were even more harmful.

    --
    Website Just Down For Me? Find out
  5. Re:Drug delivery device by GLMDesigns · · Score: 4, Insightful

    First of all banning is not a solution.

    Have you not seen how well that's worked on alcohol and weed and other drugs?

    The only question for a regulatory body would be to answer: "Do eCigarettes add unstated (or unknown) poisons into your body?"

    A secondary question would be: "Are eCigarettes better than actual cigarettes?"

    On the surface the answer is yes:

    One is not burning paper and leaves. One is primarily ingesting nicotine.

    --
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    Vote 3rd Party in 2016 and beyond
  6. Super misleading headline by phantomfive · · Score: 3, Interesting

    Yeah, a "chain-smoking" sort of addiction to anything is going to be bad for you, but with vapor you don't have all that tar in your lungs. Be careful of the ingredients in your e-juice so you don't get popcorn lung, and you're way better off compared to conventional cigarettes.

    It's better to figure out how to get a natural high, and it's better to wake up in the morning with energy naturally instead of needing coffee, but if you're still smoking tobacco then stop today and switch to e-cigs. Your future self will thank you a million times.

    --
    "First they came for the slanderers and i said nothing."
    1. Re:Super misleading headline by bluefoxlucid · · Score: 4, Informative

      The headline says e-cigarettes are harmful; the actual article says they tested a new device by putting chemicals and DNA in, generating metabolites, and reacting them to the DNA to see if the metabolites damage DNA.

      So they did a little chemical mixing without testing things like dilution in blood, protective environments of the cell, transport across cell membranes, and so forth.

  7. E-cigs don't produce "smoke".... by Ellis+D.+Tripp · · Score: 4, Informative

    which is a byproduct of combustion. They produce a vapor fog that LOOKS like smoke, but isn't.

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  8. Re: Stop it please by Anonymous Coward · · Score: 3, Insightful

    They will not. They will pile higher and deeper. All you need to notice is that every fucking crazy study about blood vessel growth or potential DNA damage gets pushed to the top of national news, but all the studies demonstrating in vivo safety never make it outta journals. It is an organized push to sell a narrative.

  9. Re:Nicotine is poisonous...period by AvitarX · · Score: 5, Insightful

    I'm pretty sure you're only half right.

    1) Nicotine is problematic, it interferes with the body's ability to fight cancer, but it doesn't look like it causes it
    2) There is no "burnt" or whatever we want to call it, "burnt" appears to be a carcinogen in general (for example, diets heavy in blackened and charred food seem to lead to GI cancers)
    3) Vaping seems to be better for the cardiovascular system than smoking.

    But, I do suspect it is not harmless, and may even be quite bad. For one thing, inhaling solvents, even food safe ones, is likely not the healthiest thing, also, It wouldn't shock me to learn that breathing 400 degree air carries with it it's own health effects.

    It still seems to be much healthier than smoking.

    --
    Wow, sent an e-mail as suggested when clicking on "use classic" banner, and got a fast response that addressed my msg
  10. Re:Drug delivery device by Nidi62 · · Score: 5, Insightful

    'E-cigarrettes' are just a blatant drug delivery device (for nicotine, a highly addictive and poisonous substance), plain and simple, and that was blindingly obvious the first time I ever heard about them.

    Tell that to the people I know who went from smoking 1-2 packs a day of cigarettes, to e-cigs/vaping, and now don't even smoke at all.

    --
    The only thing necessary for evil to triumph is for it to be pitted against a slightly greater evil
  11. Re: Drug delivery device by Anonymous Coward · · Score: 5, Informative

    Nicotine is the most dangerous part of a traditional cigarette, per mg. However, much like with coffee and caffeine, nicotine is a very small portion of the traditional delivery method. At the volumes in a normal cigarette, the burnt paper smoke is enough of a lung cancer risk even if it was completely emptied of tobacco products and additives.
    At different times, cigarettes have had different additives with different levels of inhaled toxicity, but the smoke always consists primarily of burnt plant materials, filling the smokers' lungs with carcinogenic ash and some small amount of very addictive, fairly toxic nicotine.

  12. It's interesting by Anonymous Coward · · Score: 5, Insightful

    They never seem to promote the stories that are in direct contradiction to this study. The Royal College of Physicians in the U.K. made a determination the e-cigarettes were at least 95% less harmful than cigarettes. No one cared. But every time this type of study, typically with terrible methodology no one pays attention to, is released, the media goes nuts. Saying something is safe isn't click bait worthy.

  13. Depends on intent by sjbe · · Score: 5, Insightful

    First of all banning is not a solution.

    That depends on your goals. If you primary goal is to put a lot of poor people and minorities behind bars for using drugs that seldom result in meaningful harm to others then banning is a terrific solution. Not so much for people with a sense of decency and any amount of practicality though.

  14. Re:Drug delivery device by gmack · · Score: 4, Insightful

    As long as they aren't worse for you than cigarettes they have the following advantages:

    • * They leave a lot less litter than cigarettes.
    • * They stink up the surrounding area less than cigarettes
    • * The smell doesn't get into your clothing the same way cigarettes do.

    In short. Vaping is better for everyone else.

  15. Re:Suuuuuuure, brahs. by hey! · · Score: 5, Insightful

    Most legitimate peer-reviewed journals have a conflict of interest disclosure requirement, so you just have to look at the paper to see.

    The paper isn't available to no-subcribers, but here's the guideline listed by the journal in question:

    A statement describing any financial conflicts of interest or lack thereof is published with each manuscript. During the submission process, the corresponding author must provide this statement on behalf of all authors of the manuscript. The statement should describe all potential sources of bias, including affiliations, funding sources, and financial or management relationships, that may constitute conflicts of interest (please see the ACS Ethical Guidelines). The statement will be published in the final article. If no conflict of interest is declared, the following statement will be published in the article: “The authors declare no competing financial interest.”

    The bigger question is, what is the nature of the paper, and the journal it appears in?

    The gold standard for evidence is a literature review paper published in a relevant journal that has a high impact factor for its field. Even high quality research reported in a relevant legitimate journal isn't something anyone should make any judgments based on. Science deals with evidence, and evidence in any non-trivial question tends to pile up on both sides at the outset.

    ACS Sensors is a relatively new journal published by the American Chemical Society for research in chemical sensor technology. It's not even a health-related journal. This doesn't mean the research is bad, or the conclusions are bad. It just means that they're mainly relevant as to whether this technology could be used to research the health impact of e-cigarettes.

    --
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  16. Re:Are people this stupid? by bluefoxlucid · · Score: 4, Insightful

    Uh, the headline is misleading.

    Nicotine in e-cigarettes found just as harmful as nicotine in regular cigarettes.

    UConn researchers found that e-cigarettes loaded with a nicotine-based liquid are potentially as harmful as unfiltered cigarettes when it comes to causing DNA damage.

    Oh, and it gets even better:

    UConn’s scientists decided to look into whether the chemicals in e-cigarettes could cause damage to human DNA while testing a new electro-optical screening device they developed in their lab. The small 3-D printed device is believed to be the first of its kind capable of quickly detecting DNA damage, or genotoxicity, in environmental samples in the field, the researchers say.

    First test of our new device to detect DNA damage!

    The device is unique in that it converts chemicals into their metabolites during testing, which replicates what happens in the human body, Kadimisetty says.

    Sorry, first test of our new device to simulate biological processes and see if they produce chemicals that can cause DNA.

    ... talk about non-rigorous, unethical journalistic reporting.

    E-cigarettes still don't contain smoke, 676 chemical additives (flame retardants, colorants, preservatives, pesticides, etc.), carbon monoxide, or the like. As well, the chemical additives are generally propylene glycol or vegetable glycerin, which are both generally safe (vegetable glycerin is absorbed as a metabolizable carbohydrate-like food, more of a ketone; propylene glycol is apparently actually less-harmful than that).

  17. Re:Drug delivery device by cbeaudry · · Score: 3, Insightful

    The problem with your statement is that the vaping industry is NOT the tobacco industry.

    They arent the same companies.

  18. Re:Suuuuuuure, brahs. by gnick · · Score: 3, Interesting

    A lot of people still think smoking is cool, but somehow an e-cig is like sucking on a dildo.

    Nobody still thinks smoking is cool. I never thought I'd see the day when smoking marijuana carries less of a social stigma than smoking tobacco.

    Disclaimer: I smoke.

    --
    He's getting rather old, but he's a good mouse.
  19. Re: Drug delivery device by ArmoredDragon · · Score: 3, Insightful

    Sola dosis facit venenum.

    Nicotine isn't necessarily harmful, it just depends on the amount, as with everything else. Certain amounts of it are actually beneficial for certain medicinal applications. Foods we often eat also carry nicotine, such as tomatoes, eggplant, and potatoes (all of which are nightshades, as is tobacco itself.) A whole eggplant carries about half a miligram of nicotine for example.

  20. Due to the many chemical additives ? by alvieboy · · Score: 4, Informative

    Vaper here. For about 3 months now.

    I make my own vaping fluid. It's composed of "pure" VG (VEGETABLE GLYCERIN) and "PG" (PROPYLENE GLYCOL), with added Nicotine and some flavours. PG, VG and nicotine come from reliable, trusted sources, and have no additives whatsoever. Aroma is more complex, but you can live without it if you do not trust its components, although most are at least accepted as food addictives, so should be safe.

    To be honest, the way they put it really looks like they are funded by the Big Guys.

    All I can say is for the last two months or so I feel much more healthy, no more morning coughs, I already reduced my nicotine intake for more than 50%. I tend to vape a lot, though, but as long as my sources do not lie about the base components (VG and PG) I should be way safer.

    There are no such things as "addictives", unless they mean aroma. And again, those, if coming from a reliable, trusted source, should be safe.

    Alvie

  21. Re:Drug delivery device by JackieBrown · · Score: 4, Insightful

    In fact, it's the tobacco companies pushing most of these regulations on e-cigarettes.

  22. Re: Drug delivery device by sl3xd · · Score: 4, Informative

    Nicotine itself is not a useful insecticide, primarily because it's so poisonous to non-target species: Avians & Mammals.

    As Nicotine is absorbed through the skin easily, it's also quite easy for somebody using nicotine as an insecticide to poison themselves, as well as anybody else in the area. 30-60 mg can kill a human adult, though the LD50 is generally 500-1000 mg.

    The neonicotinoids (similar to Nicotine) are extremely useful insecticides - as deadly to insects, but relatively nontoxic to birds & mammals.

    --
    -- Sometimes you have to turn the lights off in order to see.
  23. Re:Drug delivery device by MightyYar · · Score: 5, Insightful

    The alternative to a nanny state is a lot more people injuring and killing themselves, and the rest of us having to pay for it in both monetary and non-monetary ways.

    Sorry to sound snarky, but "citation needed". Seriously - I've been around long enough to see the "War On Drugs" play out, and billions of government dollars and millions of drug possessors in prison has done squat for addiction rates. Meanwhile, usage of the completely legal cigarettes has been drastically curtailed by simply restricting advertising, improving education. restrictions on second-hand smoke, and taxing them to the hairy edge of a black market.

    --
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  24. Re:Suuuuuuure, brahs. by Anonymous Coward · · Score: 5, Informative
    I have subscriber access to the paper through a university, and this is the relevant section:

    Author Contributions
    The manuscript was written through contributions of all authors. All authors have given approval to the final version of the manuscript.
    The authors declare no competing financial interest.

    Acknowledgment
    The authors thank the National Institute of Environmental Health Sciences (NIEHS), NIH, Grant No. ES03154 for financial support. We thank Islam M. Mosa for SEM images.

  25. Re:Stop it please by PlasticMan9 · · Score: 5, Informative