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Degenerative Brain Disease Found In Nearly All Donated NFL Player Brains, Says Study (npr.org)

A new study published Tuesday in the journal American Medical Association found that 110 out of 111 brains of those who played in the NFL had degenerative brain disease chronic traumatic encephalopathy (CTE). NPR reports: In the study, researchers examined the brains of 202 deceased former football players at all levels. Nearly 88 percent of all the brains, 177, had CTE. Three of 14 who had played only in high school had CTE, 48 of 53 college players, 9 of 14 semiprofessional players, and 7 of 8 Canadian Football League players. CTE was not found in the brains of two who played football before high school. According to the study's senior author, Dr. Ann McKee, "this is by far the largest [study] of individuals who developed CTE that has ever been described. And it only includes individuals who are exposed to head trauma by participation in football." A CTE study several years ago by McKee and her colleagues included football players and athletes from other collision sports such as hockey, soccer and rugby. It also examined the brains of military veterans who had suffered head injuries. The study released Tuesday is the continuation of a study that began eight years ago. In 2015, McKee and fellow researchers at the Department of Veterans Affairs and Boston University published study results revealing 87 of 91 former NFL players had CTE.

213 comments

  1. Sample bias by Anonymous Coward · · Score: 2, Insightful

    Why would someone donate their brain if they didn't think they had damage?

    1. Re: Sample bias by Anonymous Coward · · Score: 0

      But don't expect the media to be able to understand that.

    2. Re:Sample bias by ShanghaiBill · · Score: 3, Insightful

      Why would someone donate their brain if they didn't think they had damage?

      Why not? Why do you need to keep your brain if you're dead?

      I am an organ donor, and they are welcome to use any parts they can for anything useful. It may help someone, and it is less that my family has to pay to cremate.

      Disclaimer: I don't play or watch football.

    3. Re:Sample bias by FrankHaynes · · Score: 1

      They should analyze Trump's "brain" next.

      --
      slashdot: A failed experiment.
    4. Re: Sample bias by Anonymous Coward · · Score: 0

      I got dibs on your penis. I always wanted one.

    5. Re:Sample bias by arth1 · · Score: 2

      Why not? Why do you need to keep your brain if you're dead?

      Conversely, why do you need to donate anything when you're dead?
      You won't get a warm fuzzy feeling from it, because you're dead.

      And they don't give a discount on cremation for missing organs.

    6. Re: Sample bias by JoeRobe · · Score: 5, Informative

      The BBC version of this story actually discusses the sample bias, and the director of the CTE center is quoted fully acknowledging that there's enormous bias.

      http://www.bbc.com/news/world-...

      --
      The best way to predict the future is to invent it.
    7. Re:Sample bias by Anonymous Coward · · Score: 3, Insightful

      Because it gives you a warm fuzzy feeling whilst you're alive.

      It is satisfying to me to know that when I die, there is a possibility someone else might be able to benefit from that. Rather than it just being an entire waste.

    8. Re: Sample bias by BarbaraHudson · · Score: 4, Insightful

      The media understand it here - they literally used the term self-selection bias on the news this evening. Then again, Canadian news tends to cater to a more literate crowd, not those with an attention span of 140 characters.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    9. Re: Sample bias by BarbaraHudson · · Score: 1

      I got dibs on your penis. I always wanted one.

      Why wait. We have the technology to fix that now. Both ways - an addadicktome or a lopitoffofme.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    10. Re:Sample bias by Anonymous Coward · · Score: 0

      To vindicate the sport they loved.

    11. Re:Sample bias by ShanghaiBill · · Score: 1

      You won't get a warm fuzzy feeling from it, because you're dead.

      You get a warm and fuzzy feeling when you sign up. Try it.

      And they don't give a discount on cremation for missing organs.

      Yes they do. Many cremation facilities will vary fees based on the weight of the corpse.

    12. Re:Sample bias by fluffernutter · · Score: 4, Insightful

      Oh my lord, I think you just nailed all that is wrong with America in that one statement.

      --
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    13. Re:Sample bias by sjames · · Score: 2

      Because they believe they're fine and want to defend their beloved sport.

    14. Re:Sample bias by TechyImmigrant · · Score: 3, Funny

      >Why not? Why do you need to keep your brain if you're dead?

      Why do you need a brain if you are an NFL player?

      --
      I should use this sig to advertise my book ISBN-13 : 978-1501515132.
    15. Re:Sample bias by fredrated · · Score: 1

      For research? Plenty of people do that sort of thing. I will leave my body to science even though I don't think they will find anything interesting.

    16. Re:Sample bias by careysub · · Score: 1

      While this sample is going to have a much higher ratio of injured brains to non-injured brains than the general NFL population due to selection, the extremely high ratio of 110-to-1 (and 10-1 in a broader population that was studied), makes it unlikely that there are not a lot of former players out there with less severe brain trauma that are not getting flagged as brain damaged.

      --
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    17. Re: Sample bias by 93+Escort+Wagon · · Score: 2

      And a separate study came to a significantly different conclusion - that chronic traumatic encephalopathy is a leading cause of organ donation.

      --
      #DeleteChrome
    18. Re: Sample bias by interkin3tic · · Score: 5, Interesting
      The journal article itself can be found online, open access here.

      The methods section (emphasis mine)

      Study Recruitment In 2008, as a collaboration among the VA Boston Healthcare System, Bedford VA, Boston University (BU) School of Medicine, and Sports Legacy Institute (now the Concussion Legacy Foundation [CLF]), a brain bank was created to better understand the long-term effects of repetitive head trauma experienced through contact sport participation and military-related exposure. The purpose of the brain bank was to comprehensively examine the neuropathology and clinical presentation of brain donors considered at risk of development of CTE. The institutional review board at Boston University Medical Campus approved all research activities. The next of kin or legally authorized representative of each brain donor provided written informed consent. No stipend for participation was provided. Inclusion criteria were based entirely on exposure to repetitive head trauma (eg, contact sports, military service, or domestic violence), regardless of whether symptoms manifested during life. Playing American football was sufficient for inclusion. Because of limited resources, more strict inclusion criteria were implemented in 2014 and required that football players who died after age 35 years have at least 2 years of college-level play. Donors were excluded if postmortem interval exceeded 72 hours or if fixed tissue fragments representing less than half the total brain volume were received (eFigure in the Supplement).

      It sounds like they selected from donated cadavers for people who had played football. This is quite different from football players who suspected they had brain damage from football donating their brains. There would still be bias, as families who were convinced their loved ones were suffering from brain damage would be more likely to say yes to being in the study. But that's likely NOT NEARLY as big a bias as what GP is suggesting.

    19. Re: Sample bias by Bartles · · Score: 1

      No. We can only create a rough approximation of a penis. It would fool no one.

    20. Re:Sample bias by Anonymous Coward · · Score: 0

      Sorry - Such a small sample would be statistical insignificant.

    21. Re:Sample bias by Anonymous Coward · · Score: 0

      So, did the brain-damage cause them to play football?

    22. Re: Sample bias by Zontar+The+Mindless · · Score: 1
      --
      Il n'y a pas de Planet B.
    23. Re: Sample bias by tlhIngan · · Score: 5, Interesting

      The problem with CTE is it's cumulative. The more trauma, the more damage. Some of the more aggressive players have unfortunately succumbed with devastating results. Basically, who was once a family man suddenly has behavioral changes which include sudden outbursts of anger and violence that are unprovoked. Who if they weren't football players, we may have normally had jailed or committed.

      Some are even suicidal, which is a shame because most take a bullet to the head, which destroys any evidence. (Some do have enough presence of mind left to avoid damaging the head and thus allowing researchers to diagnose CTE).

      The only reason for doubt is because the NFL is rather self-interested in not promoting tackle football causes CTE. Two reasons. First, they are worried - yes, scared sh*tless - that if the association is made, parents will withdraw their kids from football programs. This may lead to lowered interest in football, which means the millions of dollars it brings in could dry up.

      The second reason is the players associations - they have successfully sued the NFL over hiding or discounting the medical issue which is more than career ending, it's life changing.

      Before CTE was even discovered, it was thought brain damage happened as a result of a major event - it was thought the brain could handle getting hit and recover, when instead it recovers irregularly. CTE is the result of repeated minor brain damage caused by the brain banging against the skull causing scarring and bruising, and which builds up over time.

      The sports associations are heavily into discounting CTE because it really affects their bottom lines. It's also why there's a ton of research going into smart helmets that can indicate when a potentially damaging event occurs, and why at least at the college level and below, the threshold for benching someone has gone from knockout or concussion to a blow that exceeds 75Gs or so, even if the player is still conscious and lucid. And after a concussion, the bench time has a fixed minimum - no longer you wake up and you're in the next game, it's minimum 4-6 weeks benched, and only the doctor can clear you. Heck, some teams have even banned tackling during practice to avoid causing more damage than necessary.

      The link between football (and other contact heavy sports) and CTE has been long proven. There are many well regarded papers behind it. The only question left is what percentage of the football playing population has CTE.

      And finally, this is a VERY recent discovery. Bennet Omalu discovered this in 2002, and the NFL reluctantly acknowledged CTE's existence in 2009, after 7 years of trying to discredit Omalu. It's just like leaded gas, cigarettes, CFCs, and global warming all over again.

    24. Re:Sample bias by Anonymous Coward · · Score: 0

      Why do you need to keep your brain if you're dead?

      so I when I'm dead, I can point at the guy without the brain with, " Ha! you brainless!"

    25. Re:Sample bias by doctorvo · · Score: 1

      Or, for that matter, why would anybody become a professional football player if they didn't have brain damage already?

    26. Re:Sample bias by mwvdlee · · Score: 0

      Why would someone donate their brain if they didn't think they had damage?

      Because they were religious and thought they needed their brains to get to heaven.

      So in essence, this research had a self-selection bias AGAINST brain damage ;)

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    27. Re: Sample bias by Anonymous Coward · · Score: 0

      Or play American football, for that matter.

    28. Re:Sample bias by Ihlosi · · Score: 1
      Because they were religious and thought they needed their brains to get to heaven.

      Sorry, if heaven doesn't include the option of getting a fresh, fully functional, undamaged brain if desired, I'd rather go to that other place.

    29. Re:Sample bias by Lisandro · · Score: 1

      "Even so, the Times notes that, even if the other 1,200 NFL players who’ve died since the project started came up clean, that’d still mean 9 percent of players—a much higher percentage than the general population—developed C.T.E."

    30. Re: Sample bias by Anonymous Coward · · Score: 0

      Just sample republicans that voted for him, then.

    31. Re: Sample bias by F.Ultra · · Score: 1

      Apparently you can fool some with even less: https://www.theguardian.com/uk...

    32. Re: Sample bias by JoeRobe · · Score: 3, Interesting

      But then there's this quote from the BBC article, which makes it sounds like it was from families who suspected that the deceased had CTE

      "Dr Ann McKee, director of Boston University's CTE Center, which led the study, cautioned against drawing any immediate conclusions.
      "There's a tremendous selection bias," she said, explaining how many of the brains were donated specifically by families who had suspected that their loved ones were suffering from CTE, which researchers believe is caused by repeated blows to the head."

      --
      The best way to predict the future is to invent it.
    33. Re:Sample bias by Paradise+Pete · · Score: 1
      They acknowledge that, and it's prominent featured in the article. The researchers specifically refrain from drawing the conclusion that you're assuming they did.

      All the brains studied were donated, she says. "Families don't donate brains of their loved ones unless they're concerned about the person. So all the players in this study, on some level, were symptomatic. That leaves you with a very skewed population." Still, McKee is adamant about one point. "We're seeing this [CTE] in a very large number that participated in football for many years. So while we don't know the exact risk and we don't know the exact number, we know this is a problem in football." Longtime concussion expert Dr. Munro Cullum says the study is helpful for several reasons. "It obviously adds to the cases in the literature," he says. "It has expanded the age range [of those with CTE] beyond just retired NFL players. And [researchers] did find increasing CTE pathology in the cases [of players] who were older. That's all useful information."

    34. Re:Sample bias by Paradise+Pete · · Score: 1

      prominently, of course.

    35. Re:Sample bias by kdn102 · · Score: 1

      Spot on! It's in the original article, but conveniently left out by /.

      "Families don't donate brains of their loved ones unless they're concerned about the person. So all the players in this study, on some level, were symptomatic. That leaves you with a very skewed population."

    36. Re: Sample bias by BarbaraHudson · · Score: 1

      If the choice is an approximation now or a real penis never, well ... ask any of the military who have received artificial dicks.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    37. Re: Sample bias by Trailer+Trash · · Score: 1

      As I've said before, if the NFL were a drug, it would have been banned years ago.

    38. Re:Sample bias by Megol · · Score: 1

      Because they want to further science? That's the main reason that people donate their bodies.

      I assume the paper will mention this and other potential biases as anything other would indicate sloppy research.

    39. Re:Sample bias by TechyImmigrant · · Score: 1

      Well no one was letting them into college on academic grounds.

      --
      I should use this sig to advertise my book ISBN-13 : 978-1501515132.
    40. Re:Sample bias by Anonymous Coward · · Score: 0

      also the sample size is way to small. it's enough to spark some curiosity toward this and further research, but defiantly not enough to make a claim like this.

    41. Re: Sample bias by Zero__Kelvin · · Score: 1

      So in your mind they knew in advance their brain would be used for this particular study? Let me guess ... are you by any chance a former Football player?

      --
      Guns don't kill people; Physics kills people! - John Lithgow as Dick Solomon on Third Rock From The Sun
    42. Re:Sample bias by Anonymous Coward · · Score: 0

      Cos they are so fat? must cost a fortune.

    43. Re:Sample bias by Lord+Kano · · Score: 1

      My fiancè's grandparents have agreed to donate their bodies for scientific research after they die and to the best of my knowledge, neither of them has had and kind of TBE.

      Some people do it because they want to make the world a better place.

      LK

      --
      "Hi. This is my friend, Jack Shit, and you don't know him." - Lord Kano
    44. Re: Sample bias by The+Grim+Reefer · · Score: 1

      Sadly, it would be pretty simple to decrease this by taking away the helmet and pads. No one is going to use the head like a battering ram for long without a helmet, which would reduce head injuries considerably.

      Something similar was looked at with head injuries in the MMA. The recommendation was to get rid of the gloves. No one can continually hit someone in the head as much or as hard without them. But just like the protection in football, removing it would probably make the sport less exciting for the spectators.

    45. Re: Sample bias by Anonymous Coward · · Score: 0

      The next of kin authorized the donation, so yes, they (the person making the donation) knew that it would be used for this particular study.

    46. Re:Sample bias by Anonymous Coward · · Score: 0

      Yep. There is an undeniable correlation between degenerative Brain Disease causing NFL Player to Donate their Brains.
      At least there IS a correlation, which is more than can be said for Global Warming.
      Causality is so 20th century.

    47. Re:Sample bias by cstacy · · Score: 1

      Why would someone donate their brain if they didn't think they had damage?

      Why not? Why do you need to keep your brain if you're dead?

      Some people also don't need it when they are alive, apparently...

      "I knew it was wrong, I shouldn't have done it...
      I should have never reconnected his Internet."

    48. Re:Sample bias by Anonymous Coward · · Score: 0

      NFL players actually have a higher rate of college degrees than the regular population.

    49. Re: Sample bias by Zero__Kelvin · · Score: 1

      I doubt the veracity of your claim, but even then the study wasn't done as you suggest. A bunch of parents didn't seek out the study because they suspected the issue. The people doing the study sought out the brains, and the parents had no greater insight into if the brains had the damage than the researchers prior to the autopsies.

      --
      Guns don't kill people; Physics kills people! - John Lithgow as Dick Solomon on Third Rock From The Sun
    50. Re:Sample bias by hey! · · Score: 2

      While this is true, 87 of 91 is an astonishingly high proportion.

      Under the "no effect/sampling bias" hypothesis, the brains donated for NFL players would be reflective of the general population of people who suffer from dementia. That would mean that Alzheimer's and vascular dementia would account for the vast majority of cases. The chances of a random sampling of 91 dementia brains turning up 87 cases of traumatic injury is vanishingly small, meaning that it is quite reasonable to conclude that playing football professionally had something to do with the rate of CTE in this sample. So given that these results hold up, the next logical question is whether the difference in this sample are due to the obvious hypothesis -- that they resulted from playing football -- or some confounding factor as yet unidentified.

      Real-life data is never perfect, which is why we do laboratory experiments -- where such experiments are feasible and ethical. But "imperfect" is far from useless, and if this study holds up, then I'd say the burden of proof is on the hypothesis that there was some kind of confounding factor.

      That really is the essence of science; it's not about establishing truth, it's about establishing burden of proof.

      --
      Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
    51. Re:Sample bias by Opportunist · · Score: 1

      And how many of them earned it vs. how many of them got it because the made the college football team look great?

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      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    52. Re:Sample bias by Opportunist · · Score: 1

      I'd rather run, especially if you hear him say "Braaaaaaaaaains..."

      --
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    53. Re:Sample bias by Opportunist · · Score: 1

      Heaven better does provide a functional brain for those that enter, pretty much everyone who gets there lacks one.

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    54. Re: Sample bias by Opportunist · · Score: 1

      And as with drugs I can only say that if people do it willingly, why outlaw it? It's not like anyone forces them to play there, every single NFL-player has the option to live a normal life with a normal job, it's trivial for them to do just that.

      Why should the government step in and dictate what people can and cannot do with their life? Yes, that may be dangerous or even self destroying, but if someone wants to do that and does not subject anyone to it that didn't himself agree to be part of the whole deal, I see no reason why they should not be allowed to do just that.

      Fuck the nanny state, let people live and die the way they want!

      --
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    55. Re: Sample bias by Opportunist · · Score: 1

      Erh... have you ever watched a game of Rugby? Or Aussie rules football?

      In short: Nope. It is neither less exciting, nor do people stop using their bodies as battering rams.

      --
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    56. Re:Sample bias by Anonymous Coward · · Score: 0

      NFL players actually have a higher rate of college degrees than the regular population.

      Yes, because they have to be in college to play football, they have degrees in business and basket weaving. Sure there are exceptions to the rule, but they got the paper, but not the life skills to back it up. That's why most athletes go back to being normal folk in their retirement.

    57. Re: Sample bias by Anonymous Coward · · Score: 0

      No, clearly having CTE causes one to play football at a high level.

    58. Re: Sample bias by interkin3tic · · Score: 1

      Yes, like I said, There would still be bias, as families who were convinced their loved ones were suffering from brain damage would be more likely to say yes to being in the study. But that's likely NOT NEARLY as big a bias as what GP is suggesting.

      Put another way, if researchers approached the family of a deceased individual and asked "can we cut their brain out now, within 72 hours of death, so you'll have to have a closed casket," many people would say no. They'd be more likely to say yes if they thought something was going on weird with the deceased person's brain.

      GP was suggesting though the researchers said "Hey, we're looking for brains to study CTE," and then were surprised to find CTE. That's not the case at all.

    59. Re:Sample bias by Anonymous Coward · · Score: 0

      Well, instead of having your body give someone sight, or a new heart.... they could drag your body out into the field and let it rot and have animals partially eat you... to study decomposition of bodies in the environment (that's how those crime investigators know how long a body has been out there in the elements). At that point, most folks would opt for simple cremation.

      Donate doesn't always mean what you think it means.

    60. Re: Sample bias by Anonymous Coward · · Score: 0

      ...or chronic traumatic encephalopathy is the leading cause of NFL's popularity.

    61. Re:Sample bias by BronsCon · · Score: 1

      If my rotting, half-animal-eaten corpse helps catch a murderer, hey, there's my warm fuzzy. That goes double for a serial killer, as my body played a role in helping others stay alive.

      --
      APK quotes people (including myself) without context and should not be trusted. Just thought you should know.
    62. Re: Sample bias by Anonymous Coward · · Score: 0

      Because ultimately it is society in general that pays for it.

      Yes, the NFL players likely have private insurance they can afford (though for how much longer private insurance will be affordable is different question).

      But all those college players who never make pro, or high school players (or other various sports like hockey or even soccer) won't have the backing of the NFL or its contracts and thus will in a lot of cases end up without insurance, thus everyone picks up the tab when they just show up at the ER.

      Then there are the side effect costs, like the cost of police to respond the domestic disturbance calls that result, or the cost (both in the physical response and the mental trauma) of the emergency services when they respond to the suicides or other violence that results.

      In short, the consequences aren't just faced by the participant but by society in general.

    63. Re:Sample bias by Anonymous Coward · · Score: 0

      NFL players actually have a higher rate of college degrees than the regular population.

      Yes, because they have to be in college to play football, they have degrees in business and basket weaving. Sure there are exceptions to the rule, but they got the paper, but not the life skills to back it up. That's why most athletes go back to being normal folk in their retirement.

      I know of a distant relation on my wife's side who was into astrophysics but couldn't afford college and was excellent at sports, so he got into college on the back of his American football abilities with a sports scholarship, then spent his time studying astrophysics, doing just enough sporty stuff to remain on the team for a while. He left college with a PhD in astrophysics and no sporting career.

      Very well played.

    64. Re: Sample bias by Anonymous Coward · · Score: 0

      You are NOT an organ donor unless you already donated it. Like your liver or something.

      If you signed up to be a donor you are just that... future donor..... not a donor yet. Who knows if you will chicken out....

    65. Re: Sample bias by Opportunist · · Score: 1

      This is true for so many things we do, should we outlaw them all? Just look around yourself, how many people lead an unhealthy lifestyle, eating too much and too fatty, sugary, stuffing their face with garbage disguised as food. Should we outlaw everything that might be unhealthy for you? What about hobbies that might lead to you getting hurt or worse? Should we outlaw any sport but, say, golf, where at best some 80 year old geezer might have a heart attack? Should we ban alcohol, too, because it eliminates inhibitions people might have against hurting someone. Not to mention that it makes people careless. Why not ban guns while we are at it, how many people get killed by... no wait, that's unconstitutional. But there's nothing in the constitution about eating, sports and booze, so we can outlaw that.

      So... we'll be a nation of people whose only allowed pastime outside of stamp collecting will be shooting stuff.

      Yes, I exaggerate, but by how much? Which of the things that people do because they consider them exciting, fun or otherwise interesting is not "unhealthy enough" to warrant a ban?

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    66. Re: Sample bias by UnknowingFool · · Score: 1

      Also the researchers acknowledged it too. However, with 110+ samples and a 99% positive rate, it would credence that there is definitely a link. Now another study in the rates of CTE in non-football players as a comparison might bolster the claim. I would suspect that comparison study would find CTE is rare in people who don't play football.

      --
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    67. Re:Sample bias by Anonymous Coward · · Score: 1

      "Heaven better does provide"

      Oh, the irony.

    68. Re:Sample bias by Anonymous Coward · · Score: 0

      He's right, you're wrong, and you're the fucking idiot

    69. Re:Sample bias by Ihlosi · · Score: 1
      Heaven better does provide a functional brain for those that enter, pretty much everyone who gets there lacks one.

      Wait ... so heaven is actually a pretty hellish place for those who enter, as they have been blissfully enjoying their lack of a working brain and suddenly they are provided with one and are forced to use it for eternity?

    70. Re: Sample bias by Trailer+Trash · · Score: 1

      I'm a straight up libertarian - I'm against banning just about anything. But just pointing out the obvious. We supposedly ban drugs because they're harmful to you, but it's clear that football is far worse physiologically than some - if not most - illegal drugs. As I said, if it were a drug it would be banned. I don't agree that it should, just delivering the news.

    71. Re: Sample bias by Anonymous Coward · · Score: 0

      Should we outlaw everything that might be unhealthy for you?

      With great responsibility needs to come great power. Voters keep saying they want us to be our brothers' keepers, so I think, therefore, we should also get to be our brothers' jailers.

    72. Re: Sample bias by superdave80 · · Score: 1

      However, with 110+ samples and a 99% positive rate, it would credence that there is definitely a link.

      That doesn't definitely mean anything. For all we know, these 110 had the most severe neurological issues (hence why they were donated by the family). Remember, thousands of people have played pro football over the last few decades. Taking a truly random sample of another 110 football players might only show a 5% rate. Then you would need to take another sample of non-football players to see if there is any significant difference before you could show a 'definite link'.

    73. Re: Sample bias by Cajun+Hell · · Score: 1

      How are those players' brains holding up? Is it working out for them, relative to American Football?

      --
      "Believe me!" -- Donald Trump
    74. Re:Sample bias by Anonymous Coward · · Score: 0

      Why would someone who slammed their head into hard objects over and over think they don't have damage?

      In theory there is a huge sample bias. In reality everyone knows football causes head injury especially the ones with the pain. So the sample is biased, but the remaining unbiased data points are likely few and far between.

    75. Re: Sample bias by UnknowingFool · · Score: 1

      For all we know, these 110 had the most severe neurological issues (hence why they were donated by the family).

      And what is your evidence behind your assertion that 110 had severe neurological issues? The research seems to suggest otherwise: "Informants reported that 43% of participants had behavior or mood symptoms as their initial presentation. . . Although the criteria for participation were based on exposure to repetitive head trauma rather than on clinical signs of brain trauma, public awareness of a possible link between repetitive head trauma and CTE may have motivated players and their families with symptoms and signs of brain injury to participate in this research."

      Remember, thousands of people have played pro football over the last few decades. Taking a truly random sample of another 110 football players might only show a 5% rate.

      Again show evidence of your assertion. By the way the number is not 110 of all football players. The number is 110 of 111 NFL players. Out of all football players here are the breakdowns:
      0 of 2 pre–high school
      3 of 14 high school (21%)
      48 of 53 college (91%)
      9 of 14 semiprofessional (64%)
      7 of 8 Canadian Football League (88%)
      110 or 111 NFL players

      Then you would need to take another sample of non-football players to see if there is any significant difference before you could show a 'definite link'.

      That was acknowledged by the study that there is no comparative study; however, an average person would not be motivated to donate their body for CTE research. However researchers could look at brains donated in the past not associated with this study and see if they can determine rates. That would require the brain being donated and properly prepared etc.

      --
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    76. Re:Sample bias by jae471 · · Score: 1

      The average career for a third round or later draft pick is only something like 2-3 seasons.

      For every Peyton Manning there are 50 Joe Shmucks in the league. Most of them know it, too.

      I work with a guy who got a degree in CS while playing D-I (Big Ten). He was undrafted, but did receive an offer to be part of a practice squad ( https://en.wikipedia.org/wiki/... ), which he turned down in favor of starting a job related to his degree.

      The idea of the "dumb jock" is largely a myth in today's professional sports climate. A lot of athletes do seem to have problems communicating clearly, but this should not be mistaken for stupidity.

    77. Re: Sample bias by JoeRobe · · Score: 1

      I don't know, donating because you think your loved one suffered from CTE sounds like a pretty major bias to me.

      That's like people donating loves ones' bodies because they think they had a heart attack, and finding that the vast majority did in fact have heart attacks. If the family thought that the person was displaying symptoms of CTE, then the probability of them having CTE is high.

      Don't get me wrong, there's almost certainly a massive causation here. I'm just agreeing with the CTE center's director that drawing a numerical conclusion isn't appropriate here. Almost certainly the CTE rate in the NFL isn't 99%...

      --
      The best way to predict the future is to invent it.
    78. Re:Sample bias by Anonymous Coward · · Score: 0

      Stop stereotyping, it makes you look incredibly ignorant. One (1!) person making a statement equates in any frickin way to America how?

      Stop giving insightful mods for stereotyping, it makes me want to generalize people on this site as ignorant. ;)

      F*ck. You people sometimes....

    79. Re: Sample bias by BarbaraHudson · · Score: 1

      And? It should be self-evident that whacks to the head can cause brain damage - those who are arguing against it have a vested financial interest in it not being true. But that doesn't make the study statistically valid.

      A better study would be to do MRIs on all players in the league both before and after one season, and again at the beginning of the next season (to eliminate the possibility that the brain completely returns to its pre-season state by then).

      It's not like they don't have the money to do it. But they certainly don't have the financial incentive, and a huge disincentive. Willful ignorance, and not just the leageu administration. Players don't want to know because then it would place the liability on them for willingly participating in a sport that would have then been convincingly demonstrated to cause brain damage, freeing the league from any liability.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    80. Re: Sample bias by superdave80 · · Score: 1

      And what is your evidence behind your assertion that 110 had severe neurological issues?

      I made no assertion that they had severe neurological issues, just that it was a possibility. But strangely, your own quote lends support to that possibility :

      Informants reported that 43% of participants had behavior or mood symptoms as their initial presentation. . . public awareness of a possible link between repetitive head trauma and CTE may have motivated players and their families with symptoms and signs of brain injury to participate in this research.""

      So why did you jump all over me for suggesting it in the first place as a possibility?

      Again show evidence of your assertion.

      Again, I made no assertion of anything. I brought up the fact that this is currently an unknown, so more study needs to be done.

      By the way the number is not 110 of all football players

      So? What does that have to do with anything? I why list the whole breakdown of other levels of sport?

    81. Re: Sample bias by Opportunist · · Score: 1

      Ok, that we can agree on. It would. Not that it should.

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    82. Re: Sample bias by Opportunist · · Score: 1

      Watching them play I have to say that mental deficits are probably a prerequisite to wanting to play this professionally.

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
  2. Hmmmm by sit1963nz · · Score: 1

    Correlation does not imply causation.

    1. Re:Hmmmm by PsychoSlashDot · · Score: 4, Insightful

      Correlation does not imply causation.

      Is the implication that playing football causes brain damage, or that having brain damage causes playing football?

      As a lifelong nerd, I've often suspected both are likely, but I suppose you're right that we need to study this more before declaring "I knew it!"

      --
      "Oh no... he found the .sig setting."
    2. Re:Hmmmm by Anonymous Coward · · Score: 1

      Obviously CTE causes football.

    3. Re:Hmmmm by sit1963nz · · Score: 1

      Correct.

    4. Re:Hmmmm by arth1 · · Score: 1

      Having brain damage might increase the chance of being asked to donate your brain.

    5. Re:Hmmmm by rtb61 · · Score: 5, Informative

      Every single concussion comes with an extent of brain damaged aligned to the severity of the concussion, every single one https://www.brainline.org/arti.... The more concussions you suffer and the worse they are, the greater your accumulated brain damage. The reason you are concussed is because, yes you brain suffered sufficient impact to cause it harm, that is why you feel concussed. It's like never damaged, bruised nerves, means in those millions of nerve bundles some where broken, severed, ceased to function, resulting in diminished capacity, as for the brain. As different parts of the brain do different things, the direction of the impact has a significant impact on the outcome, some being much more dangerous than others. What probably saves jock straps from more behaviourally visible reduce cerebral function is smaller brains in thicker skulls, with fewer neuron connections and the types of activity they indulge in, not much mental function is required for the activity, in fact reduced mental function is desirable for repetitive training behaviours.

      --
      Chaos - everything, everywhere, everywhen
    6. Re:Hmmmm by PsychoSlashDot · · Score: 2

      Every single concussion comes with an extent of brain damaged aligned to the severity of the concussion, every single one https://www.brainline.org/arti.... The more concussions you suffer and the worse they are, the greater your accumulated brain damage. The reason you are concussed is because, yes you brain suffered sufficient impact to cause it harm, that is why you feel concussed. It's like never damaged, bruised nerves, means in those millions of nerve bundles some where broken, severed, ceased to function, resulting in diminished capacity, as for the brain. As different parts of the brain do different things, the direction of the impact has a significant impact on the outcome, some being much more dangerous than others. What probably saves jock straps from more behaviourally visible reduce cerebral function is smaller brains in thicker skulls, with fewer neuron connections and the types of activity they indulge in, not much mental function is required for the activity, in fact reduced mental function is desirable for repetitive training behaviours.

      Friend, I have a policy of not shooting for +5 Funny twice in the same discussion, but man... reading your post makes me feel like maybe I've been playing too much football and it's time to donate my brain to science.

      --
      "Oh no... he found the .sig setting."
    7. Re:Hmmmm by Anonymous Coward · · Score: 0

      Read the study and perhaps you'll understand why that was a stupid thing to say.
      If you read the study and still don't understand why what you said was retarded, let us know and we'll explain it.

    8. Re:Hmmmm by Anonymous Coward · · Score: 0

      It's not convinced that playing American Football necessarily causes brain damage with 100% certainty, at least at the high school level. For example, I played high school football for four years in the late 1990s and went on to complete a computer science degree and have worked successfully as a software engineer ever since. That being said, it's probably worse in some positions than others. I played primarily as an offensive guard or tackle and although it might seem strange to somebody who's never played the game, offensive lineman actually don't take all that many big hits compared to defensive or ball-carrying offensive players. If offensive linemen have to tackle a ball carrier it means that the ball was fumbled and picked up by the defense which ideally shouldn't happen at all or at least not very often if the offense is any good. The rest of the time we're either pass blocking at the line of scrimmage (keeping the defensive lineman or linebackers from breaking through and sacking the quarterback) or advancing less than 10 yards downfield to make a block in support of a running play. In either case the contact, while rough, occurs at much slower closing speeds and there isn't as much time or field distance to pick up speed. Also, most linemen, while large and quick off the line, are slow to accelerate downfield and have lower top running speeds than players in the backfield. I very rarely had to make open field tackles in games and I never carried the ball in a game even once in four years of play. At practice (i.e. when training), the hits are generally slower speed so that technique can be evaluated and refined by coaches unless the drill is full contact but that was less common because full contact drills risk injuries that keep players out of games. Finally, offensive players need special skills that defenders don't and vice-versa, so we didn't practice tackling as much beyond how to do it safely. I only ever played on one team, but I would bet that on most teams offensive lineman probably practice tackling least of all because frankly it's not very useful to them in games. In American football, a successful offensive lineman protects the quarterback during pass plays and opens holes in the defensive line for ball carriers and lead blockers. Tackling is basically irrelevant in those situations. A well coached offensive line is not going to waste practice time on techniques that only rarely come up in games and American Football is definitely a game of specialties and specialized players with different skills coming together to make plays and advance the ball downfield or prevent the other team from doing the same.

    9. Re:Hmmmm by mvdwege · · Score: 1

      When, however, there is a possible causative agent (as pointed out below, concussions), then a correlation damn well does imply causation.

      --
      "I know I will be modded down for this": where's the option '-1, Asking for it'?
    10. Re:Hmmmm by Zontar+The+Mindless · · Score: 1

      You shouldn't parrot things that you don't understand.

      --
      Il n'y a pas de Planet B.
    11. Re:Hmmmm by Anonymous Coward · · Score: 0

      Don't forget here is a third option in which something else causes both brain damage and playing football. Maybe some evolutionary pressure on men or something.

    12. Re:Hmmmm by johanw · · Score: 1

      The first statement does not rule out the second. Both can be true.

    13. Re:Hmmmm by Mashiki · · Score: 1

      When you're dead, what do you need your brain for?

      --
      Om, nomnomnom...
    14. Re:Hmmmm by arth1 · · Score: 1

      When you're dead, what do you need your brain for?

      That makes as much sense as saying "when you're a sock, what do you need your brain for?"
      The phrase "when you" does not make sense, because there is no you. For a while, there's a carcass, owned by others. The temerity to think you have any right to decide what they do with it is appalling. Your wishes are as valid as a cow's wishes on how to prepare the steaks, i.e. only useful as a humorous device in fiction.

    15. Re: Hmmmm by Zero__Kelvin · · Score: 1

      Actually it does imply it ... The saying is that it doesn't EQUAL it.

      --
      Guns don't kill people; Physics kills people! - John Lithgow as Dick Solomon on Third Rock From The Sun
  3. 100% of my siblings ... by pedz · · Score: 1

    would have CTE if / when we donate our brains. Who says it has anything to do with sports unless "child rearing" is considered a "sport".

    1. Re:100% of my siblings ... by Anonymous Coward · · Score: 0

      would have CTE if / when we donate our brains. Who says it has anything to do with sports unless "child rearing" is considered a "sport".

      How often did your dad punch you and your siblings in the head?

    2. Re:100% of my siblings ... by Opportunist · · Score: 1

      Never. He used the frying pan, he said it hurts less.

      Thinking back, I think he was right, it sure hurt him less.

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
  4. Well yeah of course by rsilvergun · · Score: 4, Funny

    you think somebody's gonna donate a perfectly good working brain? You can sell those on eBay or Craigslist for, like $30 bucks. I gave up trying to get human brains from thrift stores back in the early '00s. It wasn't worth my time to raise a corpse from the dead only to have the local villagers come round just because I used an "Abby Normal" brain.

    --
    Hi! I make Firefox Plug-ins. Check 'em out @ https://addons.mozilla.org/en-US/firefox/addon/youtube-mp3-podcaster/
    1. Re:Well yeah of course by whoever57 · · Score: 0

      LOL!

      I used the last of my mod points just a few minutes ago.

      Bonus points for the Young Frankenstein reference.

      --
      The real "Libtards" are the Libertarians!
    2. Re:Well yeah of course by BarbaraHudson · · Score: 1

      The price of a brain varies.

      An ordinary brain might go for $30, but Einstein's brain would be worth much more.

      And then there's Trump's brain - almost priceless. Because it's never been used.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
    3. Re:Well yeah of course by Zontar+The+Mindless · · Score: 1

      I'd rather have Spock's Brain or Broca's Brain, myself.

      --
      Il n'y a pas de Planet B.
  5. Old story by no-body · · Score: 1

    known for a long time - let's see who wins now - $$ or common sense for self-preservation..

    1. Re:Old story by Opportunist · · Score: 1

      Oh please, you see what we do to the planet and need to ask that question?

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
  6. Do not assume causation by gurps_npc · · Score: 2, Interesting

    Correlation does not equal causation. Just because all professional NFL players appear to have brain damage, it does not mean that football causes brain damage.

    It could also mean that only a brain damaged person would play tackle football.

    --
    excitingthingstodo.blogspot.com
    1. Re:Do not assume causation by arth1 · · Score: 2

      It could also mean that only a brain damaged person would play tackle football.

      Or that one way of getting through college if you have problems with your brain is through athletics programs.

      But most likely, the major bias here is that players with brain damage are the ones who are asked to donate their brains.

    2. Re:Do not assume causation by UnknowingFool · · Score: 1

      That's kinda like saying 99% of coal miners have black lung disease. Clearly that means only people who have a propensity for getting black lung disease become coal miners. How much evidence would you require?

      --
      Well, there's spam egg sausage and spam, that's not got much spam in it.
    3. Re: Do not assume causation by Anonymous Coward · · Score: 0

      As a coal mine owner, I intend to use you post as an original primary source concluding that pre existing conditions like "black lung propensity" should exclude coal miners from insurance coverage.

    4. Re:Do not assume causation by Anonymous Coward · · Score: 0

      Like how playing basketball makes you tall since they're much taller than the general public? No. Healthy and smart people pick other jobs other than coal mining so that certainly is selection bias.

    5. Re:Do not assume causation by null+etc. · · Score: 1

      Correlation does not equal causation. Just because all professional NFL players appear to have brain damage, it does not mean that football causes brain damage.

      Very true. Maybe all of these football players also had something else in common, which happened to cause the brain damage.

      Oh hey, all of the football players had autopsies performed on them - maybe the autopsies caused the brain damage?

    6. Re:Do not assume causation by Aighearach · · Score: 1

      I just assumed most of them got the brain damage from their fathers. That's why they learned to like being hit in the head in first place, after all, and if your team is good you can even earn your father's love for a few hours a year.

      And some of us got to play baseball, which has different ethics regarding hitting each other.

    7. Re:Do not assume causation by Aighearach · · Score: 1

      Or that one way of getting through college if you have problems with your brain is through athletics programs.

      It seems unlikely that you would find many who turned to athletics late enough for that to make sense actually getting to play on something like a football team. I'm under the assumption that it is well proven that most of the people playing a competitive college-level sport had to begin practicing at a fairly young age. I can't really imagine somebody saying, "Gosh, I'm sure struggling in biology class, I better apply for a football scholarship."

      So what is the causal chain to explain why there are so many comments like yours on slashdot? Is it because kids with brain damage can fit in with nerds if they play enough video games?

    8. Re:Do not assume causation by SlashDread · · Score: 1

      Sure. And lung cancer causes smoking.

    9. Re:Do not assume causation by Gilgaron · · Score: 1

      I know this is Slashdot so we have to point this out every time a correlative study comes out, but as stated above, correlated does imply causation. If there is no correlation you're not going to find causation. You generally have to do some more work after the correlation is elucidated to have conclusive evidence of causation, but if you already have a mechanism (ie, head trauma causes CTE) then you're most of the way there. It'd be a hard thing to get sample size for but it'd be awesome data to see CTE relative to position, too. I'm sure the linemen are more likely to get it than the field goal kicker.

    10. Re: Do not assume causation by Zero__Kelvin · · Score: 1

      Of course one need only realize that plenty get into it out of peer pressure or because dad wants them to and they don't wish to disappoint to realize that theory doesn't fly.

      --
      Guns don't kill people; Physics kills people! - John Lithgow as Dick Solomon on Third Rock From The Sun
    11. Re:Do not assume causation by Opportunist · · Score: 1

      In Soviet Russia, it sure does!

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
  7. Whats that!? by Anonymous Coward · · Score: 0

    Beauhd has a degenerative brain disease called hillary-obsessiveitis. Terminal.

  8. Post hoc, ergo propter hoc. by Anonymous Coward · · Score: 2, Interesting

    Or, perhaps it's just that those with bad brains have a propensity toward football as a career choice. There's a reason for the "dumb jock" stereotype. Which is the cause, which is the effect?

    1. Re: Post hoc, ergo propter hoc. by Anonymous Coward · · Score: 1, Insightful

      You are a moron. Do you understand the complexities of an NFL offense? Your dumbass can read stackexchange for code snippets or look up RFCs at will (which you probably don't do), but these guys have 500+ play playbooks to fully understand where each play has at least 3 and up to 5 variations based on opposing looks and center + qb calls or MLB calls (on defense). Then they have to react to all of this in under 5 seconds of world class athletes trying to fuck up their plan.

      Dumb jock in the NFL? Think again

    2. Re: Post hoc, ergo propter hoc. by Zontar+The+Mindless · · Score: 0

      Butt-hurt sports fan detected.

      --
      Il n'y a pas de Planet B.
    3. Re: Post hoc, ergo propter hoc. by ZeRu · · Score: 1

      Most of those plays are learned in high school, after that it's muscle memory. Sure, you can't play in NFL if you're retarded, but, like with most sports, the ability to stay focused is much more important than intelligence.

      --
      If you post as an AC, don't expect me to spend a mod point on you.
    4. Re: Post hoc, ergo propter hoc. by ravenshrike · · Score: 2

      No, most of the players have vastly reduced complexity in what they have to learn. The smartest player on the team is generally the quarterback. He also has to learn the most plays and variations, as well as read the entire field during each play.

    5. Re: Post hoc, ergo propter hoc. by Anonymous Coward · · Score: 0

      College sports = Easy way out. They're like welfare babies, but with brain damage.

    6. Re: Post hoc, ergo propter hoc. by Megol · · Score: 2

      I'd argue that being focused is more important than intelligence in most line of work. If one can't apply that intelligence it is mostly useless.

    7. Re: Post hoc, ergo propter hoc. by mt2mb4me · · Score: 1

      I guess, but the problem solvers are usually absent minded. Hey look a bird.

    8. Re: Post hoc, ergo propter hoc. by Anonymous Coward · · Score: 1

      Some impressive comments.
      The helmets are shit a racing helmet manufactured is making much better helmets but the market is locked down from high school with sponsorship.
      I don't give a shit about pro sports but people dying because of low quality helmets is nuts and it's not just retired pros the brain damage starts in high school or sooner.

      http://motorsports.nbcsports.com/2014/03/24/bill-simpsons-sg-helmets-take-racing-expertise-to-football-helmets/

    9. Re: Post hoc, ergo propter hoc. by LoLobey · · Score: 1

      Actually the smartest tend to be the offensive linemen- https://en.wikipedia.org/wiki/...

      --
      We have nothing to fear but fear itself! And Spiders!
  9. But did they control? by Anonymous Coward · · Score: 0

    Maybe at some point they all read cdreimer's blog posts?

  10. Needs more samples. by Templer421 · · Score: 1

    What about soccer and baseball players?

    How can we tell drugs were not a cause?

    How about Rock Stars who have a similar pattern of drug use?

    1. Re:Needs more samples. by Aighearach · · Score: 2

      Soccer players who frequently use their heads to hit the ball may be at even higher risk than football players. Luckily, heading the ball is not very useful at the teenage level and most of the players are receiving many fewer head strikes than football players. However, some studies have suggested that a minority of players, presumably the most skilled, are already taking a large number of head strikes in high school.

      It is worth doing that sort of study, but because of macho societal stereotypes soccer players are less likely to admit concern. Soccer isn't perceived as being as dangerous, so they'd have to be pretty whiny to worry about it. But football is seen as really dangerous, so it is more accepted by the players and their families to ask those types of questions.

      Very few rock stars take lots of blows to the head. Drug use tends to damage the heart/liver/kidneys primarily. Opiates damage pleasure receptors, but you wouldn't see visible damage like you have in CTE. CTE is physical damage. It is like asking if smoking weed causes blisters. The answer is no. And when rock stars fall down, they're more likely to break an arm or to merely cut their head than to actually get a concussion. It certainly isn't normal to get repeated concussions, because if you party that hard you learn to party that hard, and if you can't even learn not to fall down and split your head open, you almost certainly already OD'd.

    2. Re: Needs more samples. by Zero__Kelvin · · Score: 1

      So you are asking if a lot of Rock Stars get hit in the head with Kilos of cocaine?

      --
      Guns don't kill people; Physics kills people! - John Lithgow as Dick Solomon on Third Rock From The Sun
  11. Proven: science is bad for you by Anonymous Coward · · Score: 0

    I don't want to get brain disease, so my choice is to not donate my brain to science. They probably wouldn't want it anyway.

  12. And then? by Hugh+Jorgen · · Score: 0

    No shit. Though most aren't intellects to start with.

  13. Previous study... by Anonymous Coward · · Score: 0

    By the same authors revealed same pattern in various sports with severe risk of head injury. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624697/

  14. Not Prove, but Yes IMPLY by DumbSwede · · Score: 5, Insightful

    Correlation does not PROVE causation. It can however strongly imply causation, especially as we can plainly see and infer the other mechanisms at play here. Let's not be like the cigarette companies here and turn a blind eye to the likely health dangers with misdirection. As for sample bias, when you are 110 for 111 I don't care what your bias is, the likelihood is that far over half of serious football players suffer brain damage of some sort or severity. Football and boxing are not likely to go away in our generation, but they will have to be modified greatly or they will eventually be considered a sport only us ignorant ancients would engage in.

    1. Re:Not Prove, but Yes IMPLY by TechyImmigrant · · Score: 1

      >Correlation does not PROVE causation. It can however strongly imply causation

      Indeed. We need a properly controlled study of the following form:

      A) Cut the heads of all current NFL players and examine their brains.
      B) Cut the heads of a randomly selected group of people from the general populace and examine their brains.
      C) See if there's a statistically significant different.

      This will both teach us if violent sports cause CTE and free up the airwaves for better quality television than stupid sports.

      --
      I should use this sig to advertise my book ISBN-13 : 978-1501515132.
    2. Re:Not Prove, but Yes IMPLY by qbast · · Score: 1

      Your properly controlled study fails to answer the question if football causes brain damage or if brain damage causes one to play football. So it still does not show any causation.

    3. Re:Not Prove, but Yes IMPLY by TechyImmigrant · · Score: 1

      True.
      We could round up a random selection of people and force half of them to play in the NFL.
      Then chop all their heads off.

      --
      I should use this sig to advertise my book ISBN-13 : 978-1501515132.
  15. Male by dohzer · · Score: 0

    Let me guess: no women were sampled? The world is soooooo sexist.

  16. What about non-NFL players? by Anonymous Coward · · Score: 0

    What is the occurrence of these problems in the general population of people who have never played US football and never suffered a traumatic head injury however caused? If the occurrence is near zero then those who think correlation doesn't mean causation might have pause to think.

    1. Re: What about non-NFL players? by Anonymous Coward · · Score: 1

      The rate of people with CTE is near zero in the general population.

  17. True... but there is other evidence of causation by Roger+W+Moore · · Score: 4, Informative

    While what you say is true but there is considerable evidence showing that the correlation is due to causation. It only occurs in sports where there is repetitive head injury and the effect is apparently similar to those produced when a head is subject to a "blast" and has not been immobilized first according to the Wikipedia page.

  18. Not correlation vs causation by sjbe · · Score: 4, Informative

    Correlation does not equal causation. Just because all professional NFL players appear to have brain damage, it does not mean that football causes brain damage.

    Snark all you want but in this case this isn't mere correlation. The condition in question Chronic Traumatic Encephalopathy. Key word there is traumatic. You get that by being hit in the head and receiving brain damage as a result of being concussed. It's the exact same condition seen in boxers and MMA fighters and hockey players and rugby players and soldiers who get concussed repeatedly. So yes it absolutely does mean that playing football in the NFL is a cause for many players of serious brain injury. The fact that some players manage to avoid such injury does not mean that a cause/effect relationship is not in play. It simply means that some managed to avoid getting concussed during their playing career. Your claim is similar to saying smoking doesn't cause cancer because not every smoker gets cancer.

  19. CTE doesn't come from drug use by sjbe · · Score: 2

    What about soccer and baseball players?

    What about them?

    How can we tell drugs were not a cause?

    Because CTE has a well known and understood cause - namely getting hit in the head. Getting hit in the head happens a LOT in american football. There is no known case in medical science of anyone getting CTE from drug use.

  20. Causation has been proven by sjbe · · Score: 5, Insightful

    Correlation does not PROVE causation.

    It's a distinction without a difference in this case. CTE comes from being hit in the head which demonstrably happens a lot in football. CTE is relatively rare among the general population who do not engage in contact sports or who haven't been violently assaulted. It is quite safe to say that playing football is a common cause of CTE. Causation is not really a question in this instance and the causal chain is well understood. Some players manage to avoid being concussed but that doesn't mean that playing football was not the cause in those who do get CTE. There is no other reasonable explanation for their condition aside from head blows received while playing a violent professional sport.

    1. Re:Causation has been proven by lordmage · · Score: 1

      Please site where CTE is rare among the general population?

      If I suspect a person has had a concussion, could I then get the brain CTE testing? I think its significant that 1 NFL brain, suspected of having CTE, did not. The sample was of NFL brains that were checked because they were thought to have CTE. Where is the control group of samples in the NFL?

      --
      I can program myself out of a Hello World Contest!!
    2. Re:Causation has been proven by Anonymous Coward · · Score: 0

      I think its significant that 1 NFL brain, suspected of having CTE, did not.

      This is easily the dumbest statement I have read this month. Let's hope it stays that way.

      So, for clarity, you're stating that 110/111 is suspicious, but 1/111 is significant? Have you been checked for CTE?

      BTW, the articles linked, and pretty much any result in the search for chronic traumatic encephalopathy will tell you that CTE is very rare. It's not very helpful to ask someone to cite (please note correct spelling) a fact in a reply to an article that contains that fact.

  21. Ask yourself! by s.petry · · Score: 3, Interesting

    If I could be paid millions of dollars a year to exercise for hours every day, travel the country, and play a game a weekend for a few months a year, and I knew the paycheck came with the risk of brain damage, would I? Yeah, probably. Would you? I'm guessing you have would have a price not much different that what NFL players make.

    As long as players are aware of risks, it should be their decision to accept or turn down contracts. I think the problem many have with the current situation is that the NFL and other agencies (allegedly) attempted to hide the risks from players.

    The "allegedly" means that I don't know for fact, and don't care to debate the allegation. If they did, it's wrong but I believe it has been since corrected.

    --

    -The wise argue that there are few absolutes, the fool argues that there are no probabilities.

    1. Re:Ask yourself! by fluffernutter · · Score: 4, Insightful

      Except the brain damage doesn't start after you sign the contract. It starts just after your dad tells you 'tough kids play football' and you suddenly find yourself on the other side of the scrimmage line from all the freakishly huge kids from the other side of town. Parents are basically volunteering their kids for this in order for their kid to have a change at the big time. That's an awful big risk.

      --
      Laws are rules for the court, but merely a bottom bar to hit for life. Think beyond laws in your actions always.
    2. Re:Ask yourself! by s.petry · · Score: 1

      Risks are, and have been covered, very heavily in all junior level sports for decades. Parents don't need to tell their kids about risk, because everyone involved in the sports organization does. Okay, if you grow up in the bayou without any organized sports parents would be required. Chances are those kids will be eaten by gators or drown noodling before they ever get drafted to college...

      --

      -The wise argue that there are few absolutes, the fool argues that there are no probabilities.

    3. Re: Ask yourself! by Bartles · · Score: 1

      Here's something that may not have occurred to you. There are people that actually like playing football. Some of them are even intelligent.

    4. Re: Ask yourself! by johanw · · Score: 1

      I think the first statement contradicts the second.

    5. Re:Ask yourself! by Anonymous Coward · · Score: 0

      Risks are, and have been covered, very heavily in all junior level sports for decades.

      Nope. Risks are often ignored, and it is difficult to impossible to get them addressed. Some people will still say you need to stop whining, play through the pain, and ignore the medical issues.

      Parents don't need to tell their kids about risk, because everyone involved in the sports organization does.

      Oh, so you don't want parents to be responsible for their children. You want the government to do it. How enlightened of you.

    6. Re: Ask yourself! by Anonymous Coward · · Score: 0

      Then clearly you're small minded. The smartest guy I ever knew was a defensive tackle on our high school football team. Lost track of him after he started working on his PhD in theoretical physics.

    7. Re:Ask yourself! by Anonymous Coward · · Score: 0

      Fun Fact: The average NFL career is about 3 years with earnings around $4M after taxes.

    8. Re: Ask yourself! by Anonymous Coward · · Score: 0

      Screw you.

      I enjoyed playing in high school. Much as I enjoyed being on the math team and taking AP courses. Much as I enjoyed learning computer science and electrical engineering in college.

      Goddamn nerds...

    9. Re:Ask yourself! by Anonymous Coward · · Score: 0

      tell us more about how children can consent to this

    10. Re: Ask yourself! by sexconker · · Score: 1

      PhD in theoretical physics

      So, not an actual science, then?

    11. Re: Ask yourself! by Bartles · · Score: 1

      I think your comment is stupid but incredibly funny.

    12. Re:Ask yourself! by rtb61 · · Score: 1

      To be fair, I fucking hate spectator sports and would accept jock strap douche bags being handed clubs and axes, with or without armour, to whack away at each other, I wouldn't watch but at least there would be less of them ;D. I did find learning about sports interesting but had zero interest in watching them over and over again, thank fuck the internet allows you to pretty much censor spectator sports pretty much out of your own personal existence. I will of course always enjoy trolling them.

      --
      Chaos - everything, everywhere, everywhen
    13. Re:Ask yourself! by toddestan · · Score: 1

      That must be the average salary, I expect the median salary to be much lower. Most players are lucky to get $1 million a year. Of course, there are the exceptions (the players everyone knows about) which pushes the average way up.

  22. Don't be stupid by sjbe · · Score: 4, Informative

    Correlation does not imply causation.

    Getting hit in the head is a proven cause of CTE. Professional football players get hit in the head commonly. Professional football players have CTE commonly. There is no other known cause of CTE aside from getting hit in the head. QED playing professional football is a common cause of CTE. The causal chain is quite intact here. The fact that some players manage to avoid brain injury while playing football does not change that causal chain.

  23. Control group is non-football players by sjbe · · Score: 4, Insightful

    Why would someone donate their brain if they didn't think they had damage?

    Plenty of people donate their brains for research who do not have CTE or other brain damage. This has been studied among the general population quite thoroughly. There is no need for every football player to donate his brain to avoid sample bias. We have a control group in everyone who doesn't play that sport.

    1. Re:Control group is non-football players by phorm · · Score: 1

      Yes, but it doesn't give accurate percentages of those affected.
      Near 100% in those donating their body to science, but that might account for only a small percentage of those involved in the sport (also, what about other sports with high-speed impact, such as hockey)

    2. Re:Control group is non-football players by Anonymous Coward · · Score: 0

      We have a control group in everyone who doesn't play that sport.

      Have we checked it against viewers?
      It isn't necessarily the playing that is the problem, it could be that viewing is just as bad.

    3. Re:Control group is non-football players by guises · · Score: 3, Informative
      It's a minimum of 9%. This problem was, of course, recognized by the researchers. From the NYT article:

      The set of players posthumously tested by Dr. McKee is far from a random sample of N.F.L. retirees. “There’s a tremendous selection bias,” she has cautioned, noting that many families have donated brains specifically because the former player showed symptoms of C.T.E.

      But 110 positives remain significant scientific evidence of an N.F.L. player’s risk of developing C.T.E., which can be diagnosed only after death. About 1,300 former players have died since the B.U. group began examining brains. So even if every one of the other 1,200 players had tested negative — which even the heartiest skeptics would agree could not possibly be the case — the minimum C.T.E. prevalence would be close to 9 percent, vastly higher than in the general population.

    4. Re:Control group is non-football players by Anonymous Coward · · Score: 0

      Read the damn article.

  24. Dain Bramage by tquasar · · Score: 1

    When I was six years old I crashed my bicycle, many more crashes on dirt bikes. I've hit my head so many times and I wonder how much my brain has been injured.

    1. Re:Dain Bramage by Aighearach · · Score: 1

      It is probably just a fruit smoothie by now. Sorry.

  25. The Report Says Exactly This. by robbak · · Score: 4, Informative
    Quote:

    This study had several limitations. First, a major limitation is ascertainment bias associated with participation in this brain donation program. Although the criteria for participation were based on exposure to repetitive head trauma rather than on clinical signs of brain trauma, public awareness of a possible link between repetitive head trauma and CTE may have motivated players and their families with symptoms and signs of brain injury to participate in this research. Therefore, caution must be used in interpreting the high frequency of CTE in this sample, and estimates of prevalence cannot be concluded or implied from this sample.

    --
    Prediction for end of Universe #42: Fencepost error in Quantum_bogosort.cpp
  26. explains... by Anonymous Coward · · Score: 0

    I guess that explains why Americans are also the most religious of all western countries.

    1. Re: explains... by Anonymous Coward · · Score: 0

      Oh rry? Does your Atlas only have two countries?

    2. Re: explains... by Anonymous Coward · · Score: 0

      It does, "America" and "Not America".

  27. Degenerative Brain Disease Found... by grep+-v+'.*'+* · · Score: 1
    Back in High School in the mid-70's, we (the High School bandies) had a saying ... "Duhhh Coach, tie my shoe."

    Of course we had a derogatory saying about drummers as well. My point is: did they check the brains before as well as after? It could just be that damaged brains like football.

    it only includes individuals who are exposed to head trauma by participation in football.

    Ahhh, so they're trying to link one to the other. Just because you've got it now and are literally in a head-banging sport, it would make sense, but are you absolutely sure they weren't damaged originally? My point still stands.

    Besides, they're risking life and limb for their glory and our entertainment, just like hockey, car racing, and just about any other sport. Are you really trying to take their livelihood away from them?

    --
    If the universe is someone's simulation -- does that mean the stars are just stuck pixels?
  28. Glad we didn't give the Chargers a billion bux by Snotnose · · Score: 2

    I have a feeling the NFL is on the way out. Thank god we told Spanos to take his ball and go home, let the saps in LA build his new stadium. Oh wait, it's some billionaire from St Louis who's gonna let Dean camp in his basement.

    Whatever, I'm glad we aren't on the hook for an expensive ego booster to some dinky dicked millionare.

  29. Not only that by Ecuador · · Score: 1

    Not only that. This study may simply indicate that football players tend to develop CTE when they die, which isn't that worrying.

    --
    Violence is the last refuge of the incompetent. Polar Scope Align for iOS
    1. Re:Not only that by Aighearach · · Score: 1

      I doubt there is a single known case of anybody developing CTE when they die. It seems highly unlikely.

      You're going to need a brand new wild guess.

    2. Re:Not only that by Anonymous Coward · · Score: 0

      Nobody has ever developed a sense of humour after death either, so you have to do your best while you're alive...

  30. Correction for primordial brains? by SpaghettiPattern · · Score: 1

    I mean, american football players aren't necessarily rocket scientists or eloquent poets.

    --

    I hadn't the slightest objection to his spending his time planning massacres for the bourgeoisie... (P.G. Wodehouse)
  31. Repeatedly smacking the brain against .... by Ihlosi · · Score: 1

    Repeatedly smacking the brain against the bone structure surrounding it will damage the brain. Brains are soft, bones are hard, if you smash the two together, it doesn't take a genius to figure out which takes more damage.

  32. Re:How about a control ? by Aighearach · · Score: 2

    I don't where all these dill weeds came from, but this isn't some blue-sky study to try to prove anything.

    It is a study to gather information about a known harm that is affecting people, that has clear and unquestioned causes, but where the extent of damage is not well known.

    Like for example if I neglect to water my tomatoes, and it hasn't rained, and I know there is damage from lack of water, I'm not doing a study to find out why the plants are turning yellow. Instead, I'm looking at how many of them are yellow, how yellow are they, what can recover, etc.

    There is not just one type of study in the world. That is something to consider if you love talking about studies in a way that would imply you read them or otherwise understand them.

  33. Now let's look at hockey by rikkards · · Score: 1

    Not as violent (not including the fighting) but hits to the boards are quite more common per game that it makes me wonder if this is going to be a concern

    1. Re:Now let's look at hockey by rikkards · · Score: 1

      Guess it is already being noticed
      http://www.tsn.ca/four-junior-...

  34. Physics is a bitch. by ledow · · Score: 2

    "People who risk smashing their heads into the floor for a living can have noticeable differences in their brains"

    Not really surprising, is it? All the padding in the world doesn't absorb the shock of decelerations like that and your brain is a squidy thing inside a bit hard thing, with a bit of leeway and fluid.

    No matter how hard the eggshell, you can still break the yolk inside.

  35. Hmmm by John+Allsup · · Score: 2

    Reminds me of a religious conservative taking the age-at-death of a number of porn stars, taking its average, and comparing that with the average age-of-death in the US, totally oblivious to those pornstars who are still alive and the contribution of their ages-at-death, which are presently unknown.

    From an epidemiology perspective, the 99% is, of course, useless. It's like saying that 99% of people who had terminal cancer died of cancer.

    On the other hand, (and why the fuck isn't this angle being spelt out more??), you have a reasonable number of brains to look at, from which you can infer ways to recognise where the brain injuries come from, and use this to better understand how often these problems occur in general. For example the questions that should be asked are about what sort of tests can we come up with to detect this sort of brain injury sooner.

    --
    John_Chalisque
  36. Correlation by SharpFang · · Score: 1

    I wonder how much of "correlation is not causation" is at play here -

    do they get the damage through playing, or do people with that specific sort of brain damage are especially apt at Football?

    --
    45 5F E1 04 22 CA 29 C4 93 3F 95 05 2B 79 2A B2
  37. The rest of the time it's HornWumpus. by Anonymous Coward · · Score: 0

    The rest of the time it's HornWumpus.

    1. Re:The rest of the time it's HornWumpus. by Anonymous Coward · · Score: 0

      PopeRatzo makes up a significant percentage too.

    2. Re:The rest of the time it's HornWumpus. by desdinova+216 · · Score: 1

      I thought the #1 was by this Anonymous Coward character? it seems like he has multiple personalities?

    3. Re:The rest of the time it's HornWumpus. by Anonymous Coward · · Score: 0

      Anonymous Coward is just the name given to everybody you posts without an account. It seems like he/she has multiple personalities because the posts could be written by almost anybody and are typically not the same person.

  38. Academic distinctions by sjbe · · Score: 2

    Yes, but it doesn't give accurate percentages of those affected.

    That's kind of an academic point of interest. Once they develop an in-situ test on a live brain then we'll get accurate counts of percent of players affected but that's not particularly important data. The important fact is that playing american football unambiguously and substantially increases the risk of CTE particularly among professionals. The exact percentage of affected players is academically interesting but not clinically important to those affected. The important fact is that the rate of affected patients is substantially higher than in the general population. The only people that might care about the exact percentages are probably lawyers.

    Near 100% in those donating their body to science, but that might account for only a small percentage of those involved in the sport (also, what about other sports with high-speed impact, such as hockey)

    What about them? It's already known that hockey players get CTE as well and similarly the exact percentages aren't the important fact. Again, whether most football players or just some have CTE the important fact is that substantial percentages of these athletes (well above the general population) are affected. The cause of their injury is no more a mystery than the cause of a torn ACL.

    1. Re:Academic distinctions by Anonymous Coward · · Score: 0

      Of course the test on a live brain matters.

      Assuming these sports don't go away completely (and they probably won't) it is incredibly useful to be able to see what difference rules changes, adjustments to protective gear, better treatment protocols, etc., will have on the players.

      Waiting a generation for a statistically significant percentage of players to start dying before we see if changes are having any effect is ridiculous.

  39. Our County Banned Contact Sports in School by Anonymous Coward · · Score: 0

    Our county banned all full contact sports in K-12 starting this fall citing the risk of CTE and other serious injuries to young and still-maturing brains. No more football, lacrosse, hockey, wrestling, or martial arts.

  40. Obligatory XKCD by jalvarez13 · · Score: 1
    https://xkcd.com/552/

    I don't mean to be rude. I just think that the self-selection bias of this study implies that we should look further into the amount of additionality that this sport brings in for CTE, and be more skeptic about the nature of the causation link.

    1. Re: Obligatory XKCD by Zero__Kelvin · · Score: 1

      Oh the blessed irony! That comic is laughing at all the weanie who deny the obvious because they once learned that correlation doesn't equal causation. Like so many here, you literally went on to do what it is making fun of after posting it. ROTFLMAO

      --
      Guns don't kill people; Physics kills people! - John Lithgow as Dick Solomon on Third Rock From The Sun
  41. CTEs are scary by Anonymous Coward · · Score: 0

    I had a few Creimer Traumatic Experiences, and let me tell you, the dry cleaning bills are no joke!

  42. He's President, you're an asshole on /. by Anonymous Coward · · Score: 0

    Tell me again who is smarter?

    1. Re:He's President, you're an asshole on /. by BarbaraHudson · · Score: 1

      Tell me again who is smarter?

      This is the same guy who, if he had just taken the money from his father and let someone else handle it using market index funds, would have at least double what he has. So tell me again how he's so smart? He's inept, both in business (6 bankruptcies, defrauded at least 3,500 creditors, multiple fines for violating anti-discrimination laws against blacks, and not a single independent thought). This is the guy who just parrots whatever he sees on TV. He could be replaced with a perl script. I can't be.

      --
      "Transparent" is a shit show that trades on every stereotype going. A man in drag is NOT a transsexual.
  43. Who could imagine.... by whitroth · · Score: 1

    That having a lifestyle that almost every day, you have anywhere from a quarter ton to half a ton of people slamming into you at maybe 10 mph, and knocking you to the ground, over, and over, and over, could *possibly* cause damage?

    How many broken bones? How many smashing shocks to your head a day?

    I read a long time ago that the *average* NFL player,, not the superstars, retire after six years with the body of a 59 yr old.

    It's not a sport. It's something suitable for blood sports in the Colliseum.

  44. causes probably from earlier by Anonymous Coward · · Score: 0

    How many NFL players played sandlot, or street football when younger, without wearing any helmets? I can't think of a single person I know who used a helmet every time they played football when not in an organized setting.

    So maybe it has nothing to do with the NFL, but with extracurricular activities. Heck, a friend had a kid who used to bash his head into walls in his house. The kid grew up to become a good football player. Don't blame his head damage on football.

  45. Concussions are a proxy for CTE by sjbe · · Score: 1

    Assuming these sports don't go away completely (and they probably won't) it is incredibly useful to be able to see what difference rules changes, adjustments to protective gear, better treatment protocols, etc., will have on the players.

    You don't need to wait for players to die for that. Concussions are a pretty good proxy for future cases of CTE and we can diagnose those today. And we already know for a fact that football helmets are rather useless in preventing concussions. They keep the skull intact but they do little to prevent your gelatinous brain from sloshing around inside your head during an impact. Frankly I don't see any way to reduce the incidence of CTE in football players without substantial revisions to the rules which probably will not happen in my lifetime.

  46. however by argStyopa · · Score: 1

    While I fully believe that football does lead to increased brain trauma (as a football player myself), let's keep note that:
    - the 'donated' brains were almost all donated specifically because they'd exhibited issues which led people to suspect such trauma.
    - even the cross-sport study again seems to have been on subjects which exhibited symptoms that would suggest brain trauma.

    At this point I haven't seen a cross section of people who DIDN'T exhibit such symptoms; certainly it's possible that *any* people that played athletics intensively in pretty nearly any sport from basketball to soccer to racquetball may also exhibit such trauma even though they don't outwardly display symptoms. I believe it's absolutely likely that ongoing football participation makes such trauma more likely and more likely to be severe, certainly, but it's also possible that most reasonably-athletic-at-one-time adults also have some small levels.

    --
    -Styopa
  47. Flawed Results by Anonymous Coward · · Score: 0

    Donated brains from those who were known to have problems leads to biased results.