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Why We Can't Have the Male Pill (bloomberg.com)

Reader joshtops shares a report: For years, headlines have promised an imminent breakthrough in male contraception. Time and again, these efforts have fallen short. Last October, for instance, researchers reported that a hormone cocktail they'd been testing curbed sperm production and prevented pregnancies. But they'd had to halt the study early because men were reporting troubling side effects, including mood changes and depression. "The joke in the field is that the male contraceptive has been five years away for the last 40 years," says John Amory, a research physician at the University of Washington School of Medicine who has been working on the challenge for two decades. A new form of male birth control would be a public-health triumph and could snag a significant piece of the contraceptive market -- which is expected to surpass $33 billion by 2023, according to research firm Global Market Insights Inc -- or possibly expand it further. In a 2002 German survey of 9,000 men in nine countries, including Brazil, France, Germany, Mexico, and the U.S., more than 55 percent of the respondents said they'd be willing to use a new form of male birth control. A later study by Johns Hopkins University estimated that the demand could yield 44 million customers in those nine countries alone. And yet major pharmaceutical companies have mostly abandoned the chase.

33 of 347 comments (clear)

  1. Hormones are nasty things to screw with... by Penguinisto · · Score: 5, Informative

    The Pill generally works for most women (and in some cases helps them stay 'regular'), a not-insubstantial number cannot go near the things without causing massive problems (irritability, fertility issues later down the road, etc). That said, it's fairly predictable, and you're not introducing anything more than just more hormones at the right times.

    It's tougher with men, since we don't have predictable cycles to monkey with (sperm production is more or less constant until the guy is well past old age), unlike eggs (which are already present at birth), sperm is made on-demand, and various hormonal interdependencies with brain chemistry is likely way more complex.

    --
    Quo usque tandem abutere, Nimbus, patientia nostra?
    1. Re:Hormones are nasty things to screw with... by Anonymous Coward · · Score: 5, Funny

      We don't really need a pill that blocks sperm, we just need a pill that alters your DNA enough to make you fail a paternity test.

    2. Re:Hormones are nasty things to screw with... by penandpaper · · Score: 4, Interesting

      Funny that, you don't have to be the biological father to pay child support. http://clementlaw.com/child-su...

      Even if the woman lies about birth control you are still liable. http://www.kidspot.com.au/birt...?

    3. Re:Hormones are nasty things to screw with... by AutodidactLabrat · · Score: 2, Informative

      Yeah, our gynocentric society is really keeping all the womens down despite our entire civilization being built around "Women are Wonderful"...

      Get fucked.

      Says no one who has ever been in a corporate board meeting and noticed the centers of power are all under MALE control!

    4. Re:Hormones are nasty things to screw with... by drinkypoo · · Score: 5, Insightful

      Even if the woman lies about birth control you are still liable.

      Yeah - it's called being responsible. Why trust what someone else tells you?

      So if not being fooled is the fool's responsibility, why do we have laws against fraud?

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
    5. Re:Hormones are nasty things to screw with... by shaitand · · Score: 3, Insightful

      And ruin sex, which is then with a rubber sex toy rather than a person. Besides that isn't responsibility it is due diligence or self-defense.

      We have birth control, morning after pills, and abortion. The argument that we can't require women to take the absolutely minimal risk associated with the morning after pill or an abortion or even carry to term if the father doesn't consent to an abortion is a weak one when we require individuals to risk death just to determine if their blood alcohol level is too high. The current system of treating a pregnant woman as the patient rather than the fetus which is 50% part of the fathers body is unjustifiable. Keeping paternity testing as taboo rather than standard and automatic procedure during pregnancy to establish fatherhood as soon as possible is unjustifiable now that it can be done early and as simply as establishing gender with a 99.9% reliable bloodtest from the mother.

      Even if you aren't willing to require minimal and reasonable levels of accommodation from women to provide something approaching equitable rights for expecting fathers, given that pro-creation is the least common motive for intercourse the father should at least have the right to waive parental responsibility while an abortion is still possible and later if the mother was negligent and didn't inform him during that time. In the case of rape the attacker should lose all related rights obviously, a man who rapes a woman has no rights to a resulting fetus and the same if a woman rapes a man and gets pregnant, she loses her rights and must go along with whatever decisions.

      Saying it is a woman's body it impacts and so it is all her decision ignores that the fetus is NOT part of her body any more than a piece of stolen jewelry she swallows. It ignores that carrying and birthing or the risks of outpatient abortion are the least of the risks, suffering, and responsibility that comes with a child. Are we really going to say it is okay for a woman to use her innate physical womb to take total control of lifelong decisions that impact another person at least as much as themselves? How can we reconcile that with the way we treat men who are even slightly assertive because women might fear the physical advantages they theoretically could take advantage of?

      Women make up about 60% of the population in the United States. They hold so much power in our society they were able to push through a constitution amendment (prohibition) that men opposed even when they didn't have suffrage. They make up 60% of the potential voters and have an even disproportionately greater representation at the polls. Politically we pretend women are disadvantaged because they have the political and social power to push that standard when in reality they hold almost all of the actual power and our policies and laws are all designed to give them all the advantages while guaranteeing no advantage can ever be given to males.

    6. Re:Hormones are nasty things to screw with... by Serge_Tomiko · · Score: 2

      It is amusing how cuckholds like yourself think. You always have to begin your conflict with another man by proving just how much smarter you are. What the fuck does biology have to do with his argument? It's amazing you wrote multiple paragraphs about condoms, which are only tangentially relevant.

      There is no legitimate reason for women to have total control over a man's life because of sex. None.

    7. Re:Hormones are nasty things to screw with... by drinkypoo · · Score: 3, Interesting

      It is the woman's body, which is why it's her decision. Whether the developing proto-child is her body or not, it has to ride around in her body, and it's therefore her decision. There is plenty of medical legal precedent.

      It seems reasonable to me that the man should bear reduced (or even zero, depending on the case) personal financial burden if he can somehow prove that he was lied to about birth control status for the purpose of conception. But that's about as far as that reasonably goes.

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
    8. Re:Hormones are nasty things to screw with... by rtb61 · · Score: 2

      No way dude. You want 100% guaranteed birth control, you create an inhaler that can simulate orgasm. One snort and you are orgasming long and hard, no muss, no fuss, the end of STDs and rape. Of course getting people to stop using it might be a bit trickier ;D.

      --
      Chaos - everything, everywhere, everywhen
    9. Re:Hormones are nasty things to screw with... by AmiMoJo · · Score: 2

      I agree with you, condoms so significantly reduce feeling and there is nothing wrong with enjoying that feeling for what it is...

      But all that I posted was said in the context of what the GP posted. If you want to enjoy sex but also don't want pregnancy or STDs then you can either use a condom or find some other method to avoid those things, such as finding someone you trust to do it with or doing stuff other than just penetration to heighten the enjoyment.

      What you can't do is what this person wants, which is to have responsibility free sex and walk away from any offspring that might be produced because you think abortions are no big deal or that fertility is the sole responsibility of the woman. If they really cared about the foetus they would not want one parent to be able to abandon it before it was even born.

      This idea is from the red pill camp, who basically want to go back to the 1950s.

      --
      const int one = 65536; (Silvermoon, Texture.cs)
      SJW, n: "Someone I don't like, and by the way I'm a fuckwit" - AC
    10. Re:Hormones are nasty things to screw with... by shaitand · · Score: 2

      "It is the woman's body, which is why it's her decision. "

      It IS my body, which iS why it's my decision whether I risk it by allowing them to take my blood to determine if I'm intoxicated... Oh wait, no, no I actually it has been determined that my right to the sanctity of my body is outweighed by the rights of others. The fundamental rights of 40% of our population with regard to the single most important thing in any parents life is a pretty damn huge thing to weigh against the risks of carrying a baby or having an abortion. Those risks were not always so low and there are still high risk situations and I would never suggest a doctor should not be able to object if one is a factor but by and large pregnancy and abortion are routine and safe medical practices.

      All that leaves is that she doesn't want the hassle or the responsibilities which are consequences of her actions just as much as the father. Women are no more entitled to a get out of jail free card than the father.

      "There is plenty of medical legal precedent."

      Which would only be relevant if we were discussing what the law is rather than it being broken and needing changed. Laws can and do change and precedents go out the window.

      "It seems reasonable to me that the man should bear reduced (or even zero, depending on the case) personal financial burden if he can somehow prove that he was lied to about birth control status for the purpose of conception. But that's about as far as that reasonably goes."

      Once upon a time "I'm pregnant" was final and responsibility for a baby was an automatic consequence both parties shared responsibility for and this would have made sense at that time. Today there are morning after pills, abortion, and adoption. Setting aside the implementation details and ramifications. If we support the ethical right of a woman to prevent a pregnancy she doesn't want for any reason at the very least we should support that father ethically would have the same right. Even if we don't support the rights of fathers to veto a pregnancy physically because of the mother's right to her body, there is no justification for not recognizing the fathers right to legally abort if she refuses to consent to the procedure.

  2. Fundamental problems, both physical and monetarily by IMathGood · · Score: 5, Interesting

    Women have a natural state where they no longer ovulate (pregnant or breast feeding) and female birth control works by tricking their bodies into going into that natural state. The big problem with male birth control is that there is no natural state where men don't produce viable sperm. All hormonal based male birth controls force the male body into some sort of unnatural state, which always leads to unacceptable side effects. Now physical barrier based male birth control might work better but its not as profitable because those methods are typically long lasting and more permanent, so the drug companies don't get a regular kickback as you don't have to buy pills every month.

  3. Or, you know, the working alternative - CONDOMS by Anonymous Coward · · Score: 3, Informative

    A pill doesn't solve all the problems with sex, just birth control.
    A condom isn't perfect, but it's a heck of a lot better than a non-existant pill with the added benefit of preventing STDs.

    I'm disappointed that the male contraceptive that basically glued the vas deferens closed but could be dissolved by another solvent hasn't taken off: https://wired.com/2011/04/ff_vasectomy/

    1. Re:Or, you know, the working alternative - CONDOMS by thewolfkin · · Score: 4, Insightful

      A pill doesn't solve all the problems with sex, just birth control. A condom isn't perfect, but it's a heck of a lot better than a non-existant pill with the added benefit of preventing STDs.

      I'm disappointed that the male contraceptive that basically glued the vas deferens closed but could be dissolved by another solvent hasn't taken off: https://wired.com/2011/04/ff_v...

      Birth control is not just for one night stands. Sometimes wedded couples decide they have enough kids at whatever number they have and would like birth control that doesn't make the wife throw up and allows them to have sex. A LOT of married men would gladly take birth control over expensive constant buying of condoms.

      --
      Just another second banana
    2. Re:Or, you know, the working alternative - CONDOMS by ranton · · Score: 4, Informative

      Birth control is not just for one night stands. Sometimes wedded couples decide they have enough kids at whatever number they have and would like birth control that doesn't make the wife throw up and allows them to have sex. A LOT of married men would gladly take birth control over expensive constant buying of condoms.

      And they all have that option already: a vasectomy.

      --
      -- All that is necessary for the triumph of evil is that good men do nothing. -- Edmund Burke
    3. Re:Or, you know, the working alternative - CONDOMS by William+Baric · · Score: 3, Insightful

      I'm guessing that for a man who is circumcised, and who already lost most of his sensitivity, a condom doesn't make much difference, but for me the condom cuts far too much sexual pleasure. I prefer masturbation (and obviously a blow job) to having sex with a condom.

      Of course, the best solution would be for society to realize that it's women who get pregnant, not men, and that it's obviously their body, their choice, and therefore their responsibility, but society doesn't like the idea that women should be responsible for their body. Society still considers that a man should be responsible for a woman's body. It's sad that in 2017 women are still considered as being unable to be responsible for anything, not even their own body.

    4. Re:Or, you know, the working alternative - CONDOMS by penandpaper · · Score: 2

      For me at least, the ability to change my mind is why I am partial to the idea of male BC. When I am a little older or at least certain on the permanency of no children then a vasectomy makes more sense.

    5. Re:Or, you know, the working alternative - CONDOMS by 914 · · Score: 2

      Vasagel ( https://www.parsemus.org/proje... [parsemus.org] ) is pretty far along, with human trials expected in 2018. It's shown good efficacy and reversibility in animal studies already.

      RISUG, which uses a different polymer, has been in human trials in India for more than a decade, with good results and no serious side effects. It's currently in Phase II trials there, which is the last step before being available by prescription.

      Most of the information on RISUG is either very superficial or very dense, but this archived page has good information with sources cited.
      http://web.archive.org/web/200... [archive.org]

      As has been stated elsewhere, the progress on these options is slow, largely because there's little money to be made in a one-time (or once a decade) shot, as opposed to a daily pill for life. Vasagel is funded entirely by donation.

      Neither of these gels provides any protection from STI, but they are currently the most promising non-permanent male birth control.

      As it stands right now, there are NO male-controlled birth control options besides condoms and vasectomy. Vasagel would allow men to take control of their fertility, notwithstanding impulsive moments when a condom may not be handy.

  4. Let's do the math by Anonymous Coward · · Score: 2, Interesting

    I would think it's far more prudent (and effective) to kill one egg than a gazillion sperm.

  5. not all that different by ArylAkamov · · Score: 3, Insightful

    Sounds about the same as the female pill regarding mood swings and depression, or altered personality. Anyone who has been with someone before and after they started taking birth control will know what I'm talking about.

  6. Google "How Much Do Vasectomies Cost" by Anonymous Coward · · Score: 2, Interesting

    "Vasectomies cost about $350 to $1000 — far less than surgery to sterilize a woman — and many insurance companies will cover the procedure."

    How much profit do they think they'll make off these pills?

    1. Re:Google "How Much Do Vasectomies Cost" by crow · · Score: 2

      Yes, but currently they're not 100% reversible. So they're not a good option for people who aren't done having kids.

  7. I've heard this before by roc97007 · · Score: 4, Insightful

    "The joke in the field is that the male contraceptive has been five years away for the last 40 years"

    Did anyone else immediately think of nuclear fusion?

    --
    Oliver's law of assumed responsibility: If you're seen fixing it, you will be blamed for breaking it.
  8. Female biology has an off switch, males do not. by juancn · · Score: 2
    Contraceptive pills for women piggyback on the existing infertile period: pregnancy and lactation.

    If you already have a basic mechanism to stop fertility in place, it's a lot easier to trigger it on command. Specially when it is designed for external control. It is the fetus that signals the mother's body to switch to pregnancy mode. This makes it a lot easier to find and trigger the chemical pathways that will do the trick.

    Males, on the other hand, do not have such mechanism, which makes this much harder to achieve without serious side-effects,

  9. Hate Facts. by x0ra · · Score: 3, Funny


    This article is pure hate fact. We all know the only reason there is no "male" birth control pill is because of the cis-gendered alt-right white nazi patriarchy. Men and women are the same and any differences only exist because of social constructs.
    </mode>

    :-)

  10. This! by alongley · · Score: 2

    Once you father a child the state OAG has you by the balls, and even if you sign a legally binding contract for child support at x dollars per month, they can come after you every three years for more for no more reason than time has passed. No requirement on the mother to prove she's capable or actually spending the money on the children neither. Staying married is only an option for some. It's cynical as heck but protection, you know, protects. You.

    --
    How do I edit my sig.
  11. Re:Because men would lie "Yeah baby, I'm on the pi by penandpaper · · Score: 3, Insightful

    Because women don't lie about being on the pill? I got some bad news for you.

  12. Re:Fundamental problems, both physical and monetar by im_thatoneguy · · Score: 2

    Yeah it's also cost/benefit.

    If you get pregnant you're in a risky medical condition. The pill might put you at risk, but you're avoiding a different risk. For the male pill you're taking someone who is in a perfectly safe medical condition and putting them in a risky medical condition with no direct benefit to the individual.

    It's a stickier ethics question than the slam dunk case for female contraceptive pills.

  13. Re:Because men would lie "Yeah baby, I'm on the pi by penandpaper · · Score: 2

    Absolutely agree and that is one reason I hope for a day with male BC so that I don't have to make a permanent decision like a vasectomy to take control of my own birth control.

    or be in a position where the other party could be misleading them.

    This is more difficult because it amounts to; "Trust no one". Being in a relationship, a healthy one at least, is built on some level of trust.

  14. Re:Will most likely cause a massive social turbule by goose-incarnated · · Score: 2

    Hardly a "massive" social turbulence. The number of births where the expected father isn't the real father is somewhere in the neighborhood of 2% (Find your own sources). This wouldn't even be a blip on the radar.

    No. It's been measured from 20% to 35%. There are multiple sources for this, I suggest you start with the CDC.

    --
    I'm a minority race. Save your vitriol for white people.
  15. Re:Fundamental problems, both physical and monetar by Cinnamon+Beige · · Score: 2

    Female hormonal birth control can cause serious and even deadly side effects, however they are acceptable in women because Pregnancy carries far higher health risks for women, especially older ones. For males such side effects are very problematic because men don't face any additional health dangers if they do not use contraceptives

    That's not how it works are all. In fact, it's somewhat worse: When the Pill got through testing, all of the side effects were considered perfectly acceptable in general. Not in a 'because pregnancy is more risky' sense, but in a flat-out 'because we do not actually give two fucks' sense...which should be a hint as to why the rules got tightened, too. (Nearly all the rounds of the FDA's rules getting tightened can be traced back to it being realized that they're fucking people over; the one exception is when it was everybody else being lax getting us a nice global panic while a paper-pusher at the FDA went "Nope!" and refused to allow Thalidomide to get approved in the US...well, for the uses wanted for it at the time. It's actually a very good cancer drug & approved for that particular use.)

    We've since tightened up the rules, but since the Pill got approved before then it stays on the market even though you'd never get it through now.

  16. Re:We're talking about men right? by Pfhorrest · · Score: 2

    It's not about asking women to trust men, it's about not asking men to trust women.

    If each party can see to it on their own that they're not going to make a baby, then nobody has to take anybody's word that they're handling it on their end, and if they're both taking separate precautions the pregnancy prevention is even more effective anyway.

    --
    -Forrest Cameranesi, Geek of all Trades
    "I am Sam. Sam I am. I do not like trolls, flames, or spam."
  17. Re:Will most likely cause a massive social turbule by Cinnamon+Beige · · Score: 2

    Hardly a "massive" social turbulence. The number of births where the expected father isn't the real father is somewhere in the neighborhood of 2% (Find your own sources). This wouldn't even be a blip on the radar.

    No. It's been measured from 20% to 35%. There are multiple sources for this, I suggest you start with the CDC.

    If memory serves, the higher numbers are specifically for those children for whom paternity testing is done--the 2% number is what I've seen given as predicted for what might be expected with a truly random sample, and usually gets brought up to remind people that the 20%-35% number is better understood as the percentage of men who are actually right in suspecting that the child isn't theirs.