Slashdot Mirror


A Search For Insomnia Genes Involving 1.3 Million People is the Largest Genetic Study Ever (technologyreview.com)

In a genetic study of unprecedented size, scientists have searched for inherited causes of insomnia in the DNA 1,310,010 people. From a report: They found 956 different genes linked to the sleep disorder, drawing closer to an explanation of what causes it and, perhaps, to new ways to treat it. The study appears to be the first gene search to involve DNA collected from more than one million people. "It's amazingly massive," says Stuart Ritchie, a psychologist involved with genetics research at the University of Edinburgh. On Twitter, scientists let loose with superlatives: "Holy cr*p," "mammoth," and "Wow!" The project involved crunching genetic and medical information collected from the UK Biobank and the consumer DNA testing company 23andMe. It was led by Danielle Posthuma, a neuroscientist specializing in statistical genetics at Vrije University, in Amsterdam.

13 of 37 comments (clear)

  1. Re:23andme? by TechyImmigrant · · Score: 2

    They ask for consent individually for each study.

    --
    I should use this sig to advertise my book ISBN-13 : 978-1501515132.
  2. Re:Disorder? by Anonymous Coward · · Score: 5, Insightful

    Yes, it is *absolutely* a disorder.

    It is horrible. Fucking horrible. People who have never been afflicted have no concept of how shitty you feel all the time, and the overwhelming frustration of laying in bed, completely exhausted, and uncompromisingly wide awake.

    The strong medications are either tolerance-building, or cause problematic symptoms like sleep-walking, or both. And of course the weak medications are weak.

    And you are surrounded by people who know nothing about fucking anything giving you stupid and thoughtless advice as if they have just cured you.

  3. Chosen because you can call at any time by mykepredko · · Score: 1

    Makes sense - if you're doing a study, you should pick a group of people you can ask questions of at any time.

  4. This article makes me tired. by xxxJonBoyxxx · · Score: 1

    Time for a nap.

  5. Evolution in action by nospam007 · · Score: 1

    Younger people sleep well at night, because they need to be alert during the day for hunting mammoths and stuff.
    Older people sleep lightly or hardly at night, so to be able to hear predators, enemies and sick young ones. Since they don't participate in hunts anymore, they can do naps during the day.

  6. Re:Disorder? by subk · · Score: 1

    You're obviously either too dumb or too square to try weed... Nature solved this problem for us eons ago.

    --
    Now, if you'll excuse me, I have backups to corrupt.
  7. Re:Disorder? by asackett · · Score: 1

    I've Delayed Sleep Phase Disorder which I don't suffer because I'm self employed, but I get whacked by wicked insomnia every now and then that makes life pure shit. A week of sleeping zero to two of every 24 hours knocks me out of work, and at two weeks I can't follow idle chit-chat any more and have switched off the telephone ringers. At a month in, it's just a complete bummer and death seems an acceptable, though not preferable, resolution. (I'm not suicidal; don't need a hotline.)

    On the up side, being self employed means that I can better control the trigger conditions of the insomnia and don't have to worry about the DSPD getting me fired for being habitually late to work.

    --

    Warning: This signature may offend some viewers.

  8. Re: Disorder? by gweilo8888 · · Score: 1

    Oh, get over yourselves with the flamebait moderation on this post. I have suffered with chronic insomnia for between three and four decades, but you know what? I can still tell a joke when I see one. Parent post didn't deserve the downvote, just s quiet chuckle or a roll of the eyes.

  9. Re:Disorder? by asackett · · Score: 1

    In my experience, weed reduces the frequency of it but once an episode begins all I get for smoking myself into a stupor is redundancy -- I'm already stupefied by the absence of sleep.

    --

    Warning: This signature may offend some viewers.

  10. Re:Disorder? by subk · · Score: 1

    Yes, good question. I have found CBD-rich Indica strains work well. THC doesn't hurt, but Sativa is usually counter-productiive. The best is straight CBD oil dropped sublingually.

    --
    Now, if you'll excuse me, I have backups to corrupt.
  11. Re: Disorder? by subk · · Score: 1

    Put a few drops of CBD oil under your tongue and thank me when you wake up 15 hours later. :P

    --
    Now, if you'll excuse me, I have backups to corrupt.
  12. Re: Disorder? by asackett · · Score: 1

    Don't tell me, let me guess: You're a budtender.

    --

    Warning: This signature may offend some viewers.

  13. Physical exertion by iamacat · · Score: 1

    Seriously, if you can't sleep, maybe that's because you are not tired. Of course if you do a one off work out, sore muscles will keep you awake. But else, do what nature intended and take a sufficiently challenging hike to be TIRED. You'll sleep like you probably don't remember. Seeing that people sit on their butts these days, I am not surprised they can't sleep at night.