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Doctors Tried To Lower $148K Cancer Drug Cost; Makers Tripled Its Price (arstechnica.com)

Slashdot reader Applehu Akbar writes: Imbruvica, a compound that treats white blood cell cancers, has until now been a bargain at $148,000 per year. Until now, doctors have been able to optimize dosage for each patient by prescribing up to four small-dose pills of it per day.

But after results from a recent small pilot trial indicated that smaller doses would for most patients work as well as the large ones, its manufacturer, Janssen and Pharmacyclics, has decided on the basis of the doctors' interest in smaller dosages to reprice all sizes of the drug to the price of the largest size. This has the effect of tripling the price for patients, and doctors have now put off any plans for further testing of lower dosages.

The researchers are retaliating by urging clinical investigators to test whether the expensive pill could be safely given every other day -- and by calling on America's public health regulators to investigate the drug's pricing.

17 of 384 comments (clear)

  1. Crimes against humanity by Anonymous Coward · · Score: 5, Insightful

    Hang them

    1. Re:Crimes against humanity by www.goatse.ru · · Score: 3, Insightful

      Martin Shkreli got off scot-free in my book. These people should be hanged for all the deaths they cause to people who can't afford their drugs.

      Big Pharma is JUST LIKE big insurance, folks. They write the laws in their own favor.

    2. Re:Crimes against humanity by b0s0z0ku · · Score: 1, Insightful

      No: it can mean the same amount of taxes if the money is spent intelligently.

      Start cutting:
      (1) The military. Our Minuteman and nuclear sub force is enough to deter invasion. Both are cheap to maintain. Not so about the constant homicide campaigns with boots on the ground. Withdraw from the Middle East, Korea, and Latin America.
      (2) The "war on some drugs." Focus on treatment, not punishment. And see above about Latin America and our military/DEA.
      (3) Mass incarceration. See above. Then make sentences realistic and focus on rehabilitation.
      (4) Subsidies for coal/oil industries.

      Right, then we should have a few trillion with which to fund research that actually SAVES human lives without raising taxes much, if at all. The dividends paid by a healthier population may actually be revenue-positive.

    3. Re:Crimes against humanity by Type44Q · · Score: 3, Insightful

      Our Minuteman and nuclear sub force is enough to deter invasion.

      Right, keep the nuclear deterrents but get rid of any and all defensive weapons. Boats? Bullets? Rifles, tanks, attack aircraft? "We don't need 'em anymore; we've got nukes."

    4. Re:Crimes against humanity by b0s0z0ku · · Score: 1, Insightful

      There's a middle ground you know. Keep the nuclear deterrent against invasion. Keep a military organized primarily as a self-defense force against invasion. Withdraw from countries we have no business fighting in.

    5. Re:Crimes against humanity by HornWumpus · · Score: 2, Insightful

      Because that worked so well in the 1930s?

      You're not completely wrong. We should cut back, but let's stay real. Can the Europeans really be trusted to run their business without adult supervision?

      --
      John McAfee 'It was like that time I hired that Bangkok prostitute; to do my taxes, while I fucked my accountant'
    6. Re:Crimes against humanity by PopeRatzo · · Score: 3, Insightful

      Without profits, there is no incentive to do any R&D.

      That's utter horseshit. You've been so brainwashed by the ubiquitous marketing of a late-stage capitalist system that you can't even fathom someone doing research without corporate sponsorship. It's robbed you of imagination.

      https://en.wikipedia.org/wiki/...

      --
      You are welcome on my lawn.
    7. Re:Crimes against humanity by PopeRatzo · · Score: 3, Insightful

      What I cannot fathom is someone paying tens or hundreds of millions for a clinical trial.

      The numbers that get thrown about regarding the cost of conducting clinical trials are inflated by thousands of percent. Profits are disguised as costs. It's a huge scam. Plus, much of the cost of clinical trials in the US is subsidized by the taxpayers.

      --
      You are welcome on my lawn.
  2. Just because you can doesn't mean you should. by Known+Nutter · · Score: 3, Insightful

    Much of what is wrong in the world is represented in this story. I get it.. recovery of R&D costs, profit, all of that. This seems to go far beyond the pale, though.

    --
    Beware of the Leopard.
  3. Public interest by RyanFenton · · Score: 5, Insightful

    Lots of folks here are allergic to the idea of the public interest having any role in public policy. I understand where you're coming from - "if it isn't helping me now..."

    But here's the thing - properly funding public research is WAY cheaper than these ruthless extortion tactics we've turned healthcare into for the past few decades.

    I mean, it's crazy cheaper to prioritize a working public healthcare, and yes, research programs.

    As in, most of the rest of the world would consider how we run things a complete joke.

    But somehow, because it involves some sort of public interest at play... it's somehow seen as a threat(?)

    But somehow, these stories after stories of business people deciding to extort folks, with such calculated corporate smiles on their faces are seen as not a threat.

    Which is rather odd - those same folks would see Andy Griffith as a misty memory ideal don't see how basically that's exactly the kind of cruel selfishness personified that he ranted at in half of the episodes of his show.

    It's just so bizarre to see what passes for debate and morality in discussions on Slashdot these days.

    Ryan Fenton

    1. Re:Public interest by Anonymous Coward · · Score: 2, Insightful

      As in, most of the rest of the world would consider how we run things a complete joke.

      As a Canadian I have to say that most of us *do* consider how you guys run things a complete joke and we have been thinking that for quite a few decades now.

      Your two biggest problems are as follow:

      1. You all seem to fear common good for some reason. The word "communism" doesn't mean "Russian" or "poor" or "dictator". Communism is "the philosophical, social, political, and economic ideology and movement whose ultimate goal is the establishment of the communist society, which is a socioeconomic order structured upon the common ownership of the means of production and the absence of social classes, money and the state." - wikipedia

      For example, a lot of civilized countries have universal healthcare. That's communism.

      Trying to have everyone on the same level doesn't mean making everyone live with the bare minimum, modern society already lets poor people live better than kings that lived centuries ago. Sure, not everyone will drive a Ferrari but that's luxury.

      Another thing is that your way of is similar to a spoiled child. You don't care that others don't have anything as long as you get everything. Or it doesn't matter if laws favour the rich because even though you're poor right now you're going to be rich some day.

      2. You have the most ridiculous system of government on the planet. Only two parties, which areas divided between those two parties and the elected people can still vote however they feel while disregarding what the people who voted for them are asking? That's not democracy.

  4. This is the economic system... by VeryFluffyBunny · · Score: 5, Insightful

    ...that so many Americans identify with and defend patriotically and decry anything else as Socialism/Communism/government overreach. This is the free market and minimal regulation at work, doing what it's supposed to do, regardless of anything except profits and share prices, and you vote for it like true patriots every few years.

    --
    Debate is a form of harassment. Do not question my truth.
    1. Re:This is the economic system... by fahrbot-bot · · Score: 3, Insightful

      ...that so many Americans identify with and defend patriotically and decry anything else as Socialism/Communism/government overreach. This is the free market and minimal regulation at work, doing what it's supposed to do, regardless of anything except profits and share prices, and you vote for it like true patriots every few years.

      "'Money before people', Ted, it's the company motto, written right on the lobby floor. It just looks more heroic in Latin."
      -- Veronica Palmer, Better Off Ted, Season 1, Episode 4.

      --
      It must have been something you assimilated. . . .
  5. In Europe drugs are 1/10-1/20th of USA price by lamer01 · · Score: 4, Insightful

    Everytime I go there and go to a pharmacy to get a prescription refill while abroad, the price charged is usually even lower than my copay in the USA. It is an obscenity against US consumers. We should really be in the streets with pitch forks about this but we are not. The fact that most drugs are covered and only copay is needed obfuscates the real retail prices that would cripple anyone without insurance. I was shocked about the prices in europe. Most americans would not even need prescription coverage for most of those drugs as their street price is ridiculously low compared to what we pay in the USA

  6. et tu by harvey+the+nerd · · Score: 3, Insightful

    His candor doesn't make the foulness of his predatory actions ok.

    His abuses of abusive laws are not ok. An "et tu" defense that others do it doesn't make it ok.

  7. It's the prices, stupid! by mspohr · · Score: 4, Insightful

    The entire US health care system is a scam run by doctors, hospitals, pharma, insurance companies. Prices for health care in the US are four to ten times that of the rest of the world. Other developed countries have universal care and better health indicators than the US and they spend less than half what the US spends to cover just part of the population.
    We have the most expensive, least effective health care in the world.
    No other civilized country would let pharma get away with these obscene prices for drugs. Other countries control prices. However, the US is run by a crony capitalist system where corporations, etc. buy congress to protect their profits.

    --
    I don't read your sig. Why are you reading mine?
  8. Re:Sigh. by BlueStrat · · Score: 1, Insightful

    Dear America,

    Fix your fucking healthcare system.

    Sincerely,

    The civilised world.

    Dear Europe (and much of the rest of the "civilized" West),

    Please start paying for your own national defense, the nuclear arsenals, standing armies, air forces, navies, etc to match Russia and China.

    Then we can talk about us spending that money we currently spend to protect YOUR asses on healthcare instead.

    The US is bankrolling your 'free' healthcare.

    Just say "thank you" and STFU, 'mkay?

    Strat

    --
    Progressivism (aka US 'Liberalism'): Ideas so good they need a police/surveillance-state to enforce.