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Urgent Needs To Prepare For Manmade Virus Attacks, Says US Government Report (theguardian.com)

A major U.S. government report warns that advances in synthetic biology now allow scientists to have the capability to recreate dangerous viruses from scratch; make harmful bacteria more deadly; and modify common microbes so that they churn out lethal toxins once they enter the body. The Guardian reports: In the report, the scientists describe how synthetic biology, which gives researchers precision tools to manipulate living organisms, "enhances and expands" opportunities to create bioweapons. "As the power of the technology increases, that brings a general need to scrutinize where harms could come from," said Peter Carr, a senior scientist at MIT's Synthetic Biology Center in Cambridge, Massachusetts.

The report calls on the U.S. government to rethink how it conducts disease surveillance, so it can better detect novel bioweapons, and to look at ways to bolster defenses, for example by finding ways to make and deploy vaccines far more rapidly. For every bioweapon the scientists consider, the report sets out key hurdles that, once cleared, will make the weapons more feasible.
The Guardian references a case 20 years ago where geneticist Eckard Wimmer recreated the poliovirus in a test tube. Earlier this year, a team at the University of Alberta built an infectious horse pox virus. "The virus is a close relative of smallpox, which may have claimed half a billion lives in the 20th century," reports The Guardian. "Today, the genetic code of almost any mammalian virus can be found online and synthesized."

179 comments

  1. Creating human malware by Applehu+Akbar · · Score: 1

    CRISPR makes it easier for ISIS to create a doomsday virus, but at the same time the tech makes it easier for us to respond to threats like this. If the No GMO activists force us to recuse from using CRISPR because of this potential use, all it does is prevent us from fighting back. Could this perhaps be their original motivation?

    1. Re: Creating human malware by Anonymous Coward · · Score: 0

      Seems more likely that the CIA or Mossad would make the virus and give it to ISIS than ISIS making it themselves.

    2. Re:Creating human malware by WindBourne · · Score: 1

      It DOES make it easier to create new solutions against it. What CRISPR does not do, is improve detection of such. A virus could be let lose in an area and allowed to infect a population. Imagine a simple rhino virus that renders a woman infertile. Then release it in 'enemy' territory. Within 10 years, the population is already showing a downturn. And nobody would be the wiser.
      Without ability to detect strains of virus, this will end up being used sooner, not later.

      --
      I prefer the "u" in honour as it seems to be missing these days.
    3. Re:Creating human malware by Anonymous Coward · · Score: 0

      Idiot, simple rhino virus spreads around the globe easily, only a fool like you would think it would stay in the one place for 10 years.
      And that no one would notice all the women becoming infertile is just laughable.

    4. Re:Creating human malware by crimson+tsunami · · Score: 1

      We have had the ability to detect strains of virus for a long long time.

    5. Re:Creating human malware by WindBourne · · Score: 1

      Porky/Red tide, the idiot is you. Rhino virus does NOT spread around the globe. Various strains do, but the same strain does not. ANd the strains die out rather quickly.
      And it would take about 1-3 years for a nation to figure out that infertility is a problem and then another 3-10 years to isolate the reason.

      --
      I prefer the "u" in honour as it seems to be missing these days.
    6. Re:Creating human malware by WindBourne · · Score: 1

      No idiot. You have to be able to isolate them and then know what oyu are looking for. What we have the ability to do is titers for antibodies of KNOWN virus.
      Back in 1981 when I worked at CDC and we had NO IDEA what was causing AIDS, there was a HUGE dash to figure it out. It took over a decade. And the tech has not changed a whole lot. Why? Because you have to sample it, grow it, isolate it, and then fingerprint it. None of these are easy. Likewise, throw in Prions and your search space is even bigger.

      --
      I prefer the "u" in honour as it seems to be missing these days.
    7. Re:Creating human malware by crimson+tsunami · · Score: 1

      The tech hasn't changed much since 1981? LOL

    8. Re:Creating human malware by terrycarlino · · Score: 1

      Then a year or so to isolate who cause the infection, and about 30 minutes to turn them into a green glass sheet, because when you screw with a nations ability to survive they pretty much don't care if people get mad at them because nuke you.

    9. Re:Creating human malware by WindBourne · · Score: 1

      sure it has. BUT, the current approach is still fairly similar. You obviously have not a single clue.

      --
      I prefer the "u" in honour as it seems to be missing these days.
    10. Re:Creating human malware by WindBourne · · Score: 1

      pretty much. I suspect that is why talibahn has not done a bio attack like this. They are far to located in single location. AQ will not do it because of religious reasons. BUT, a goup like ISIS or possibly a renegade in China, Russia, or the west, could do it and not think twice.

      Basically, we DO live in interesting times.

      --
      I prefer the "u" in honour as it seems to be missing these days.
  2. First to isolate race wins... by Anonymous Coward · · Score: 0

    Reality is there are quite a lot of racial differences in DNA (unique identifiers) .. First nation/peoples who learn to target race(and use it) will rule the world and all the empty buildings.

    My money is on the Asians.

    1. Re:First to isolate race wins... by Anonymous Coward · · Score: 1

      Too many different types of Asians.

      It'll be the Han Chinese.

    2. Re:First to isolate race wins... by Anonymous Coward · · Score: 0

      Inherit the world.

    3. Re: First to isolate race wins... by Anonymous Coward · · Score: 0

      America has too diverse a population for that to be effective against. It's the homogenous racial populations (like Asian and African) that that would ostensibly be more vulnerable.

    4. Re:First to isolate race wins... by AHuxley · · Score: 1

      Switzerland would be my winner in that.
      How to stop the EU from invading Switzerland?
      Switzerland would need a solution to stop the EU from keeping an invading EU army supported.

      --
      Domestic spying is now "Benign Information Gathering"
  3. Re:Solution to overpopulation? by Archtech · · Score: 3, Funny

    Hello, Adolf! Is that really you after all these years?

    --
    I am sure that there are many other solipsists out there.
  4. Translation by Archtech · · Score: 0, Troll

    "A major U.S. government report warns that advances in synthetic biology now allow scientists to have the capability to recreate dangerous viruses from scratch; make harmful bacteria more deadly; and modify common microbes so that they churn out lethal toxins once they enter the body".

    Translation:

    For many years the US government has been pursuing research into biological warfare, which it believes would help it to overcome adversaries (like Russia and China) that cannot be defeated by brute force. It is now achieving some success, and realizes that as volumes are ramped up and large-scale manufacture gets underway, some leakage is inevitable.

    Therefore it makes sense to lay the basis for blaming any such leakage on "terrorists". Which is, of course, absurd as ISIS actually works for the US government. (They are cheap, expendable, and can commit atrocities without any risk of blowback against the USA).

    --
    I am sure that there are many other solipsists out there.
    1. Re:Translation by Anonymous Coward · · Score: 0

      And what's most important is that we are doing all this alone without any international collaboration and built the most beautiful, airtight, level 4 virus impenetrable dome around the country and make the international community pay for it.

    2. Re:Translation by Anonymous Coward · · Score: 0

      Interesting. Please provide a few references.

    3. Re:Translation by Anonymous Coward · · Score: 0

      Mod parent down please. This is simply another Russian or Chinese troll.

    4. Re:Translation by Archtech · · Score: 1

      https://www.sott.net/article/3...

      https://joninews.wordpress.com...

      https://orientalreview.org/201...

      For a really funny treatment of this rather serious topic, see https://en.wikipedia.org/wiki/... where it is alleged that, having run a biological weapons research program from 1918 until 1973, the Pentagon then decided to end it. Cold. Yeah, sure.

      --
      I am sure that there are many other solipsists out there.
    5. Re:Translation by Archtech · · Score: 1

      Please provide a few references for your statement. I am not a troll of any kind, but a concerned British citizen pointing out massive and flagrant breaches of international law.

      --
      I am sure that there are many other solipsists out there.
  5. Limitations of deadly viruses / deadly bacteria by DrYak · · Score: 5, Informative

    and modify common microbes so that they churn out lethal toxins once they enter the body

    In the specific case of viruses, it's counter productive. As some hyper dangerous viruses have shown like Ebola, it you kill your host, you won't have a host into which to reproduce anymore.
    Viruses aren't full autonomous life forms, their just simple genetic code (recipes that need an actual host's cell with cellular machinery to interpret the code and produce more viruses).
    The "evolutionary target" that most viruses aspire to become (i.e.: the fittest mutant that are selected by natural selection) isn't ebola, it's the common cold : a virus that is relatively benign and doesn't harm the host too much, so it can safely keep replicating in a still-alive host, and can have the time to find other alive hosts to which to transmit (while leaving as much alive hosts as possible for a potential future new round of infection by a new variant)

    If some mad scientist create some lab monster that produces lots of lethal toxins, that synthetic virus is at a high risk of killing the host without having had any chance to spread.

    With bacteria, the problem is similar but in reverse : bacteria are autonomous life forms - cells that multiply on their own. They basically don't need us (beyond a few disease-inducing bacteria that rely on bodies for environment (relative warmth) and food).
    Whatever weird dangerous gene the mad scientist sticks into them, that poison isn't necessary to achieve what it basically wants (to multiply).
    So, unless these poison-producing genes are somewhat linked to some critical biochemistry needed by the bacteria, there will be no evolutionary pressure to keep producing the poison (quite the opposite : due to the way they replicate their genome (=single origin) bacteria tend to lose useless gene. Less bullshit genes = less times spent in replicating that bullshit)

    (also, if the bacteria needs some environment for potential victim (say, again warmth) the same logic as with virus applies (a dead host won't be producing any warmth anymore).
    The first infected victim with a synthetic bug will die, but over lots of generation, the bacteria will eventually lose the poison-producing gene because it will be able to replicate faster (and thus over take the slower replicating bacteria that have more bullshit gene) (*).

    So yeah, a few mad scientist could try to CRIPR their way in clandestine lab to build super-bugs with ultra-killing genes, but if these monsters kill too fast, they won't stand a long term chance.
    It will suck for the first few patients who get sick, but the bugs will have a hard time taking over the world.

    ---

    (*) - conversely, that's why antibiotic resistance started to become "a thing" only recently when antibiotics started to get used on large scale (by the agricultural industry, by over prescription, etc.). Before that large scale antibiotics use, there's any pressure to justifiy the bacteria keeping the extra genetic material coding for the resistance (e.g.: the plasmid carrying beta-lactamases).

    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
    1. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      If some mad scientist create some lab monster that produces lots of lethal toxins, that synthetic virus is at a high risk of killing the host without having had any chance to spread.

      So instead of straight away pumping out lethal toxins, the bacteria first produces something thats not found in human body but isn't dangerous however when the concentration rises high enough it start producing the toxins .. after the host has had days to weeks to spread the infection before showing any symptoms?

    2. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      A highly infectious virus that kills its host after 7 days without too unpleasant symptoms may not have an effective long-term strategy, but it doesn't need one: Survival of the fittest is only a thing when survival is a goal. An "intelligently-designed" virus may have other objectives. Besides, man-made viruses don't need to be so indiscriminate: The digital world has Stuxnet, which was designed to spread far and wide, but only "kill" in a highly specific environment, that of the Iranian uranium enrichment facilities. Now think of the biological equivalent.

    3. Re:Limitations of deadly viruses / deadly bacteria by rmdingler · · Score: 4, Insightful

      Appreciate your sane, well-reasoned argument.

      Natural phenomena and happenstance have been mutating viruses and bacteria for billions of years, selecting for favorable survival traits. Mammals have been evolving for +/- 160 million years, with some of that focus on disease-resistance.

      Despite many plagues prior to antibiotics, and the mass transit in use today that can spread a threat worldwide like no other time in history, humans have proved difficult to drive to extinction.

      --
      Happiness in intelligent people is the rarest thing I know.

      Ernest Hemingway

    4. Re:Limitations of deadly viruses / deadly bacteria by phantomfive · · Score: 5, Insightful

      The obvious counter-argument is to create a virus that spreads easily, waits a few months, then kills people as quickly as ebola.

      --
      "First they came for the slanderers and i said nothing."
    5. Re:Limitations of deadly viruses / deadly bacteria by fish_sauce · · Score: 2

      The common cold have already been concentrated into a deadly form in labs but it is only used for research. At least currently. There are several ways you can weaponize it and we can in fact do that today. We have been able to for some years now. Oh and common cold should be considered a group name. There are hundreds of viruses that can cause a cold.

      One of the main issues is infecting one country, it can easily spread to your home country.
      Another issue is mutation risk. Biology is imperfect. The weapon could mutate which could render the vaccine protection ineffective.

    6. Re:Limitations of deadly viruses / deadly bacteria by GuB-42 · · Score: 1

      This is a good argument for natural viruses/bacteria, not for bioweapons.
      An attacker probably doesn't want to destroy humanity, or create a stable life form. They want to weaken their enemy, and even a short lived virus can wreck havoc on the economy of a country, as well as create mass panic.

    7. Re:Limitations of deadly viruses / deadly bacteria by rjdriver · · Score: 1

      No need to wait for a mad scientist to recreate an animal virus in a lab, the semi mad ones have been doing it since the 1930s by using mouse brains and other animal tissues to grow or weaken the viruses used in vaccines. And in the process, transferring animal viruses into the human population causing various new diseases that our immune systems don't know how to handle.

    8. Re:Limitations of deadly viruses / deadly bacteria by EvilSS · · Score: 1

      Actually a fast-burning virus like that is ideal for a bio-weapon. Disperse and infect the people exposed to it immediately, they die in a gruesome way to scare the shit out of the populous, then die out so it (hopefully*) doesn't spread out of control.

      *because "hope" will save us all! or something like that.

      --
      I browse on +1 so AC's need not respond, I won't see it.
    9. Re:Limitations of deadly viruses / deadly bacteria by mjwx · · Score: 1

      In the specific case of viruses, it's counter productive. As some hyper dangerous viruses have shown like Ebola, it you kill your host, you won't have a host into which to reproduce anymore. Viruses aren't full autonomous life forms, their just simple genetic code (recipes that need an actual host's cell with cellular machinery to interpret the code and produce more viruses).

      In addition to that excellent post, with viruses (as well as parasites and bacteria) there is an inverse relationship between complexity and transmissibility. A more complex a virus the larger and heavier it needs to be. This limits its transmission vectors. A virus that spreads easily like flu or the common cold is rarely fatal. It transmits easily because it is airborne and it can only be airborne because it is simple and light enough to be carried by air. As viruses get heavier and more complex, the transmission vectors must become equally complex, becoming waterborne or foodborne. Ebola requires direct contact with infected blood and to do so, causes its victims to bleed and haemorrhage which ultimately causes their death.

      Because the transmission vector is easily stopped by basic hygiene, complex viruses tend to be difficult to spread. Ebola has a shocking mortality rate, some strains up to 100%, but the number of infected are relatively few compared to the total population and with quarantines, can be completely isolated. Yellow Fever, which is often transmitted by mosquito, has a 20% mortality rate if untreated and a 5% mortality rate if treated... And we consider Yellow Fever to be pretty F-ing serious.

      So using adapted viruses as a weapon isn't effective. Not simply because for a virus complicated enough to have a high mortality rate, you need a very complex method of dissemination. Its not simply a matter of dumping a vial of virus into a seedy corner of the city, in order to defeat the inevitable quarantine you need to infect all people within a short amount of time before the virus is discovered. Its also not a case of just make Ebola lighter so it can be airborne, doing that would make it significantly less potent.

      Which leads me to my last point... the Human body is pretty damn good at defending itself. The immune system can adapt and fight off new viruses, especially if they aren't complex. Given a bit of help with modern medicine, it can do a sensational job.

      I'm less concerned about adapted viruses because they're not very effective weapons. There's a reason dictators still prefer chemical weapons, Sarin, VX, Novichok, literally pick your poison is that they're easy to disperse and near 100% effective. Not to mention less dangerous to the handlers and easier to store. Given that viruses are hard to spread, the notion of one suicide patient zero infecting themselves with some form of super-ebola being able to wipe out entire cities is laughable, we've already got procedures on how to handle mass outbreaks of deadly natural diseases, these can apply artificial ones.

      --
      Calling someone a "hater" only means you can not rationally rebut their argument.
    10. Re:Limitations of deadly viruses / deadly bacteria by mikael · · Score: 1

      The longer it hangs out in the human body, the more change there is of the immune system detecting it and mounting a response. So like a cold virus, it's important to start replicating and spreading as fast as possible by getting the host to sneeze and cough.

      --
      Vintage computer adverts: http://www.vintageadbrowser.com/computers-and-software-ads
    11. Re:Limitations of deadly viruses / deadly bacteria by mjwx · · Score: 1

      The obvious counter-argument is to create a virus that spreads easily, waits a few months, then kills people as quickly as ebola.

      How do you propose to control the mutation? Anything with a life cycle as short as a virus will undergo mutations at a rapid rate.

      Also, Ebola does not kill quickly. Two to twenty one days for incubation, death six to sixteen days after symptoms appear, even then some strains of Ebola only have a 25% mortality rate. OK, that's fast for a virus, but incredibly slow in human terms.

      Anything remotely like Ebola needs to be extremely complex. Ebola requires direct contact with bodily fluids to be transmitted. So how would you propose to infect an entire city's worth of people with a complex virus without it being detected? In order to be infectious, you need noticeable symptoms (well thats kind of backwards, the whole idea of looking for infections is to look for the symptoms they produce).

      Surely it would be easier to build a missile and load it with nerve gas, not only will it be cheaper, but cause considerably more deaths and carries less risk of failure.

      --
      Calling someone a "hater" only means you can not rationally rebut their argument.
    12. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      How do you propose to control the mutation?

      Who knows? Trial and error is how we find a lot of shit out.

    13. Re:Limitations of deadly viruses / deadly bacteria by phantomfive · · Score: 2

      So how would you propose to infect an entire city's worth of people with a complex virus without it being detected? In order to be infectious, you need noticeable symptoms

      Make it spread through the air.

      --
      "First they came for the slanderers and i said nothing."
    14. Re:Limitations of deadly viruses / deadly bacteria by mr.mctibbs · · Score: 2

      Why are you focusing on the viruses that make headlines, and not the ones that are actually dangerous? All we need is for somebody to take a historical plague for which we all have immunity and tweak it so our antibodies don't recognize it -- say, do a repeat of the Spanish Flu. That be enough of a disaster to slow civilization to a halt.

    15. Re:Limitations of deadly viruses / deadly bacteria by parkinglot777 · · Score: 1

      Some thing like this already happen in 1984 in the U.S. Even though it was not very serious issue, it is shown the potential of seriousness...

    16. Re:Limitations of deadly viruses / deadly bacteria by mjwx · · Score: 4, Interesting

      So how would you propose to infect an entire city's worth of people with a complex virus without it being detected? In order to be infectious, you need noticeable symptoms

      Make it spread through the air.

      Have you ever wondered why Ebola has never become airborne.

      The reason I said "complex" is because a complex virus like Ebola is far to heavy to be airborne. To be airborne a virus needs to be light and there is an inverse relationship between complexity and lightness. Also to be airborne, the virus needs to grow on the inside of the lung or throat, which significantly decreases it's effectiveness as the lung is the most advanced particulate filter known to man.

      There's a reason few people die from the flu or common cold... and most of them die from complications exacerbated by the virus, not the virus itself.

      You also didn't mention how you'd control the mutation.

      --
      Calling someone a "hater" only means you can not rationally rebut their argument.
    17. Re:Limitations of deadly viruses / deadly bacteria by mjwx · · Score: 1

      Why are you focusing on the viruses that make headlines, and not the ones that are actually dangerous? All we need is for somebody to take a historical plague for which we all have immunity and tweak it so our antibodies don't recognize it -- say, do a repeat of the Spanish Flu. That be enough of a disaster to slow civilization to a halt.

      Because these are the viruses that actually kill people and Ebola is the one that most mouth breathers may have heard of. Yellow Fever is one of my other favourite examples but a lot of people don't realise its a real disease, many people think it's just a white guy with a penchant for Asian ladies.

      Ebola and other hemorrhagic diseases tend to be the biggest killer, Ebola has a mortality rate of 25-90%, Yellow fever has a mortality rate of 20% if left untreated or 5% if treated... I believe, but have no evidence that this is reduced to 1% if treated at a modern facility... However we treat the disease very seriously, If I haven't got my immunisation card coming back from South America, I'll find it very hard to get back into Australia or Europe.

      Spanish flu had a mortality rate of 10-20%... And most of those died due to complications combined with the disease. In fact the main reason it spread so far is because of World War 1 and the fact Influenza was not understood by the average person. So we had troops stacked into rooms like cordwood, no wonder it spread and we had limited resources to treat it. Influenza rarely kills on its own, the vast majority of influenza deaths are from complications or secondary infections like Pneumonia. We now now how to treat influenza outbreaks so that very few die from them, even in developing nations there is enough common knowledge about isolating sick people to limit infections, knowledge most educated westerners didn't have in 1918.

      Diseases and viruses are simply not effective ways to kill people. A home made rocket full of home made mustard gas will kill more people.

      --
      Calling someone a "hater" only means you can not rationally rebut their argument.
    18. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      What about a bird flu virus like the H1-Nx variety?
      Yes, I know, these aren't manmade(except for Asian urbanites who live with their livestock...) but this is the real threat as I understand it.

    19. Re:Limitations of deadly viruses / deadly bacteria by Gilgaron · · Score: 1

      If your goal was terrorism, you wouldn't care about creating a persistent threat, just a big splash of 'airborne ebola/HIV' or whatever that burns out quickly would be just fine. If you're a nationstate looking to wipe out enemies and then move in, it'd be even preferable. That the mutating population would regress to a less virulent form or wouldn't spread far beyond those initially exposed wouldn't matter. Unfortunately I'm not sure how you could propose countermeasures. Even for plenty of regular pathogens, once you're showing symptoms (and the problem is identified) you may already be a goner.

    20. Re:Limitations of deadly viruses / deadly bacteria by angel'o'sphere · · Score: 1

      It will suck for the first few patients who get sick, but the bugs will have a hard time taking over the world.
      Depends how infecting they are and how they get deployed, and then again we have this thing called air planes ...

      --
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    21. Re:Limitations of deadly viruses / deadly bacteria by chill · · Score: 1

      The Atlantic has a good article in their current issue that talks about this. However, their angle is not synthetic viruses, but rather just the natural terrors that have arisen from places like The Congo and how the world is horribly unprepared for a repeat of the 1918 Flu Epidemic.

      It is a very good read.

      --
      Learning HOW to think is more important than learning WHAT to think.
    22. Re:Limitations of deadly viruses / deadly bacteria by Gilgaron · · Score: 1

      It needn't be complex, the virus co-opts host cell behavior anyway. Over-express a few select host cytokines in addition to the normal viral protein manufacture.

    23. Re:Limitations of deadly viruses / deadly bacteria by angel'o'sphere · · Score: 1

      We had that, it is called HIV. Thanks to modern medicine (which means since roughly 1995) it does not kill quickly anymore, or people can actually live long with it. It did not kill as rapidly as Ebola, though.

      Other viruses like SARS or chicken influenza spread really rapidly, can kill quickly, depending on strand, but have a relatively short incubation time.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    24. Re:Limitations of deadly viruses / deadly bacteria by eth1 · · Score: 1

      If some mad scientist create some lab monster that produces lots of lethal toxins, that synthetic virus is at a high risk of killing the host without having had any chance to spread.

      Wouldn't that kind of depend on the toxin? Take something lie acetaminophen: very safe until a threshold is passed, and then it suddenly becomes very deadly (a few hours to get an antidote, or you need a liver transplant to survive). The virus could have plenty of time with no symptoms to spread itself. Probably very hard to pull of something that specific, though, and not very likely to happen.

    25. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      the fittest mutant that are selected by natural selection) isn't ebola, it's the common cold : a virus that is relatively benign and doesn't harm the host too much, so it can safely keep replicating in a still-alive host, and can have the time to find other alive hosts to which to transmit (while leaving as much alive hosts as possible for a potential future new round of infection by a new variant)

      Ebola's only weakness is it kills too quickly, almost the opposite of HIV which is transmissible for years before symptoms reveal themselves and when untreated have much higher mortality rates than the common cold.

    26. Re:Limitations of deadly viruses / deadly bacteria by hey! · · Score: 1

      Right, so natural pathogens like influenza, polio, diptheria, tuberculosis and measles cold have never been a public health problem.

      There are a number of problems with your reasoning. First, it assumes the most simple minded genetic engineering target: make this pathogen kill everyone as immediately and spectacularly fatal as possible. You would engineer your pathogen for the maximum political and economic impact in the target population. For example you could engineer something like tuberculosis, which before anti-TB drugs often caused recurring bouts of debilitating acute illness over a person's lifetime before ultimately killing him.

      Ultimately a pathogen like polio which causes neurological damage inflicts a bigger burden on your enemy than a disease that causes death. Some encephalitis strains are fabulously expensive to survive, because they can require lifetime institutionalization. Or here's an idea: what about a diseases which disfigured people?

      Second, your reasoning ignores the actual mechanisms of contagion. Some pathogenic diseases like the common cold or HIV are infectious in the incubation period, before symptoms emerge. Others, like Ebola or measles, aren't infectious until some symptoms emerge, but can spread while the symptoms are still too mild to cause alarm. Still other pathogens can be transported with no contact at all with an infected person, via contaminated objects, food or waste.

      Third, you also ignore the ecology of human pathogens. Many epidemics are of "zoonotic" pathogens -- pathogens whose natural ecological focus are wild animals and livestock. Influenza is a zoonosis whose original focus was wild bird populations but spreads to humans via livestock. The pathogens' behavior in the "enzootic reservoir" runs the gamut from completely asymptomatic (hantavirus) to often fatal (West Nile Virus) -- they all can work to keep the pathogen alive until it can reach people. Human-only pathogens like the common cold also manage to maintain themselves in the human population indefinitely producing countless variant strains, many of which produce few or no symptoms, until the circumstances are right to explode, like a time bomb.

      Engineering an effective bioweapon is a multidisciplinary exercise. There's genetics and medicine, of course, but to make the engineered pathogen effective as a weapon you need knowledge of public health and possibly ecology.

      --
      Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
    27. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      The obvious counter-argument is to create a virus that spreads easily, waits a few months, then kills people as quickly as ebola.

      Or something that spreads easily, has no symptoms whatsoever, and causes sterility. That would be 100% effective in 1 generation.

      But I'd prefer something that turns people in zombies, so I can get a crossbow and a bad attitude and take over the world.

    28. Re:Limitations of deadly viruses / deadly bacteria by WindBourne · · Score: 1

      Any virus developed by a major nation for attacking any enemy, will likely be such that it will something like a rhino virus that makes men or women infertile. At the same time, you give a vaccine against it to your own ppl. IOW, rather than attack them directly, you instead go after the long shot.
      OTOH, somebody like ISIS or AQ, would simply make an avian flu strain merge with human flu, so that it can be easily spread amongst humans. Then release it in the enemy nations.

      --
      I prefer the "u" in honour as it seems to be missing these days.
    29. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      When I was in NBC school we were taught some misinformation* but for what its worth the view in the school was that biological warfare was useless, at least from a military point of view. Things I remember include:

      1) biological agents have a tendency to die off when exposed to normal UV radiation as in sunlight

      2) the results are unreliable making planning difficult

      3) getting useful dispersion is also difficult

      4) delay for effect is too long and too variable

      5) getting rid of biological contamination is pretty easy

      Since chemical weapons don't have these difficulties there just isn't much use in biological warfare. For non-military use (e.g., in terrorism) these issues may not be so detrimental, but we already have pretty well established ability to deal with biological threats.

      * such as the official army radiation poisoning tables essentially having all effect levels having the associated dosage increased by an order of magnitude so what is effectively a lethal dose looks like it will only cause mild symptoms

    30. Re:Limitations of deadly viruses / deadly bacteria by WindBourne · · Score: 1

      First off, we shed MANY MANY virus that has absolutely NO symptoms. The only reason we go after diseases is because their symptom is a side effect of the virus that harms the host. So, going after say Ebola as your base model would be a foolish mistake.
      HiV can be used, but way to slow. Rhino Virus and/or flu are the correct ones to have. A smart disease would be to develop a rhino virus that either makes somebody infertile (slow way to destroy the enemy), OR you do a 2 part attack. Basically, create a rhino virus that CAN manufacture a poison, but is not triggered to do so. Then spread it amongst your enemy territory. Then later on, release another virus that will trigger the poison slowly.

      Bear in mind that AQ/Talibahn has had access to one of the best forms of bio-chem attacks. In particular, all they had to do was obtain an avian flu bug from china, and then modify it to jump to humans. How to do that? Infect multiple ppl with human and avian flu. Then put them with other humans. The flu strains WILL combine. The question is, which parts? You might lose 100 ppl, but then again, AQ/talibahn do not value human life (conservative all the way through). Once you have a variant that kills and spreads to humans, simple send ppl to enemy territory to get sick and spread it.

      --
      I prefer the "u" in honour as it seems to be missing these days.
    31. Re:Limitations of deadly viruses / deadly bacteria by crimson+tsunami · · Score: 1

      Someone would obviously notice if a country started mass vaccinating its entire population for an unknown mystery virus. It wouldn't be hard to get a sample and see whats going on. On the plus side though all the anti-vaxxers would be rendered infertile, so it's not all bad.

    32. Re:Limitations of deadly viruses / deadly bacteria by Sumus+Semper+Una · · Score: 1

      Unless it's something like HIV which attacks the immune system directly, in a few months the host will have already killed the virus off and developed immunity to it. And if it's like HIV, people are going to notice its existence pretty fast.

      It seems to me that the biological expertise and knowledge required to make a planet- or country-devastating biological weapon isn't yet the sort of thing a small group of individuals could carry out successfully. Now, something developed by a country or organization that can be used as a terror weapon that causes hundreds to thousands of horrifying deaths but doesn't spread far is another matter. I'd actually be surprised if those don't already exist. The scary part about those is the threshold to access their methods of creation becoming lower and lower.

    33. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      How do you propose to control the mutation? Anything with a life cycle....

      You were given a hypothetical scenario where a properly designed biological weapon wipes out substantial portion of the world. Did you want exact instructions on how to assemble virus with toothpick and duck tape in a multi-cooker?

    34. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      *bullshit* show evidence of a single virus that infects humans and has no symptoms.
      Why do you think no one would notice such an experiment?

    35. Re:Limitations of deadly viruses / deadly bacteria by Gilgaron · · Score: 1

      What? You're fighting off viruses (and bacteria, and protists, maybe some microanimals if you've been swimming in natural water bodies) as you type this, asymptomatically. It's kind of why AIDS is a big deal.

    36. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      My concern isn't so much that there could be a super fast killer bug, but a bug that kills over 2 months or so, transmits with nearly no symptoms for the first month and then wreaks havoc.
      One that you could now you could replicate it, aerosolize it and seed across a large area.
      It may turn into a common cold after a while, but it might wipe out a large geographical regions of humanity in the process.

    37. Re:Limitations of deadly viruses / deadly bacteria by terrycarlino · · Score: 2

      That wasn't misinformation. The military only cares about military effectiveness. If a radiation dose doesn't make you immediately militarily ineffective it's not considered a lethal dose.

      So any dose rate that results in you still being militarily effective for the next 24 hours isn't lethal as far as they're concerned. You can die after you win the battle.

    38. Re:Limitations of deadly viruses / deadly bacteria by DigiShaman · · Score: 1

      Mutations don't matter when the casualty count is as high as a thermonuclear exchange.

      --
      Life is not for the lazy.
    39. Re:Limitations of deadly viruses / deadly bacteria by allawalla · · Score: 1

      What's the difference (in terms of weapon development) between engineering a virus that kills people vs. engineering an super anti-viral? It seems like there are enough bugs in the world that a country that could develop a cheap (relatively speaking) and effective anti-viral to even something as innocuous as the flu/cold could gain a huge economic advantage over everyone else in the world. There are reasonable theories that many of the issues associated with economic development in Africa come down to the plethora of tropical diseases on the continent. I guess you could even say that anti-malarials and mosquito control already fall into this category. It doesn't sound nearly as scary, but has almost the same net effect.

    40. Re:Limitations of deadly viruses / deadly bacteria by jeff4747 · · Score: 1

      So yeah, a few mad scientist could try to CRIPR their way in clandestine lab to build super-bugs with ultra-killing genes, but if these monsters kill too fast, they won't stand a long term chance

      That's probably a perk.

      Let's say you're in your volcano lair in Elbonia, and you're wanting to harm, say, the US. The fact that your pathogen will likely burn itself out in the US and not get back to Elbonia is a good thing from your perspective.

    41. Re:Limitations of deadly viruses / deadly bacteria by jeff4747 · · Score: 1

      The way a virus spreads is to cause disease - our symptoms are the effects of the virus replicating itself so that it can spread.

      If it lays dormant for a while, it can't spread naturally until it becomes active.

    42. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      I don't know if you're being creative enough. Imagine an engineered virus with mild flu symptoms that also, say, caused increasing blindness over the course of weeks. Or interfered with kidney function to some small but nontrivial percentage, causing a slow onset of jaundice? Sure those aren't immediately lethal, but they're more than capable of crippling a society. With the add-on benefit that once release and discovered, there would be a mass panic as everyone with an actual cold either floods the healthcare system or refuses to leave their homes. We're talking societal collapse scenarios unless there's a mitigation plan in place.

      What I'd be even more concerned about would be a retrovirus engineered to splice lethal DNA into people with certain genetic markers, while only reproducing or staying dormant in people without the markers. You know, like if you only wanted to kill a single ethnic population. The virus would spread easily through the larger population, it wouldn't even have to spread quickly. By the time you realized what was happening, it could be so out of control that the only solution is to physically isolate the susceptible population.

      Granted, both scenarios require more advanced skill in genetic engineering. But the way the technology is moving... would it be out of the question for a disgruntled lab scientist to cook something like this up? I doubt it, given a few more years at the rate of current advancement. People worry about nuclear proliferation... but we're allowing a technology to spread freely and unchecked that has far, far more potential for an extinction level event.

    43. Re:Limitations of deadly viruses / deadly bacteria by WindBourne · · Score: 1

      Hey, porky/red tide. You are fucking LOADED with Virus. A large chunk of our DNA is nothing BUT VIRUS. The only reason that we know a number of the other virus is that they produce symptoms, such as sneezing, or death, so then we look for these virus.
      Chances are good that you have Herpes and simply do not show it. Just like Genital warts. Heck, the vast majority of STI were asymptomatic (Im sure new ones have been discovered but they are likely asymptomatic, otherwise, you would hear about it in the press).

      --
      I prefer the "u" in honour as it seems to be missing these days.
    44. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      Yes, we are lucky that Ebola is too heavy to be airborne. That's all it is, luck. There's no particular correlation between the physical size of a virus and how deadly it is. The "Spanish Flu" was not much different from any other H1N1 influenza virus, but it killed 10-20% of the people infected - tens of millions of people. If a strain of flu were genetically engineered to kill people, it could be much worse. Naturally occurring viruses are subject to evolution, so they generally won't be very lethal because killing the host kills the virus. This would not be a limitation with a bioweapon - an aggressor would not want the virus to linger in the environment after the attack anyway.

    45. Re:Limitations of deadly viruses / deadly bacteria by CaffeinatedBacon · · Score: 1

      Fuck off again Windy. Stop blaming me every time you fall for a troll. Cut back on the lies too while you're at it.

    46. Re:Limitations of deadly viruses / deadly bacteria by crimson+tsunami · · Score: 1

      Do you just reply to yourself with obvious nonsense, just so you can blame it on me?
      Doesn't seem very honourable of you.

    47. Re:Limitations of deadly viruses / deadly bacteria by Anonymous Coward · · Score: 0

      The only mutations that count, are those that don't kill the host while still bestowing immunity.

      Why do you feel so compelled to control mutations. If it is already a kill all humanity virus, what worse could go wrong?

      Or to answer your question more directly, if you want to control mutation, remove as much non-coding space in the genes as possible and design it so it requires many of its genes to be functioning to reproduce.

      Or to answer your question in a different way. Make your virus so it can mutate as much and quickly as possible. Being adaptive will make it much better at ending humanity.

      You argue nerve gas is much cheaper. I could argue nukes are cheaper than nerve gas. But biologics have an advantage in that you don't have to send a missile that can be tracked back to you. Just infect someone over there. Tainted potato chips maybe. Wipe them out without them ever knowing who did it. Much less costly (in collateral damage).

  6. Nature is bad enough by Anonymous Coward · · Score: 0

    Iâ(TM)m more scared of nature to be honest. Especially Chinese people sleeping with birds seems to spread many new flus

  7. sums up this article with 4 words : by Anonymous Coward · · Score: 0

    WE are all dead.

  8. The Sky is Falling, and ... by vtcodger · · Score: 1

    The Sky Is Falling, and we must ... we must ... we must ... Honestly, We don't have the slightest idea what to do about this even at the conceptual level. Much less the practical level.

    If we are lucky, the threat will be ignored. If not, we'll do something stupid, absurd, and counterproductive that provides no actual security. Anti-viral theater.

    --
    You can't see ANYTHING from a car, You've got to get out of the goddamned contraption and walk...Edward Abbey
    1. Re:The Sky is Falling, and ... by Gilgaron · · Score: 1

      Yeah unfortunately, even without regulatory hurdles, those exposed to an artificial plague would be long dead before you even figured out what it was or how it worked.

    2. Re:The Sky is Falling, and ... by jeff4747 · · Score: 1

      Yeah, basically the only way to deal with this is "Don't shut down the CDC".

    3. Re:The Sky is Falling, and ... by 1ucius · · Score: 1

      Presumably, they can stockpile antiviral meds, DARPA better antivirals, run quarantine drills, upgrade continuity of government plans, etc.

      Just having a plan to execute will save lives vs doing nothing.

  9. Virus Attacks by phantomfive · · Score: 1

    It's really not a problem, just use OpenBSD, they're invulnerable to Spectre now, and the put security as a top priority (only two remote holes in the default install in a long time!), so you're probably safe.

    Oh, what? Like human viruses? What is the bs doing on Slashdot I'm going to write a nastly letter to Logan.

    --
    "First they came for the slanderers and i said nothing."
  10. There's a comic about this by lucasnate1 · · Score: 1

    There's a comic called "Genocide man" about a world where open source extended to biology as well, which brought many changes, including deadly man made plagues. It is a rare known gem that I highly recommend.

    http://www.genocideman.com/?ca...

    1. Re: There's a comic about this by Anonymous Coward · · Score: 0

      Is it anything like After the Bomb?

    2. Re: There's a comic about this by lucasnate1 · · Score: 1

      There is some similarity, but instead of a world war between states, it becomes a conflict between humans (some of which are legally enhanced) and mutants.

    3. Re: There's a comic about this by Anonymous Coward · · Score: 0

      The TMNT After the Bomb series of RPG books was interesting.

  11. Registered /.ers opinions of the Win64 model by Anonymous Coward · · Score: 0

    Your software is just fine - well written, functional... I'm going to continue using the Host File Engine by mmell February 17, 2017

    (APK's work), I've flat out said it's good by BronsCon February 11 2016

    his hosts program is actually pretty good by xenotransplant August 10 2015

    his hosts tool is actually useful for those cases in which one does indeed want to locally block stuff outright while consuming minimum system resources by alexgieg September 25 2015

    I like your host file system by Karmashock September 09 2015

    I do use APK's host file on all my systems at home by OrangeTide December 01 2017

    I personally use a HOSTS file blocker produced from a genius called APK by 110010001000 October 27 2017

    * See subject: Best part is this Linux 64-bit model is faster & more efficient (does 2x the work in 1/2 the time)

    APK

    P.S.=> Enjoy a faster/safer/more reliable internet... apk

  12. Gibson was right. by dwywit · · Score: 1

    Shades of "Burning Chrome"

    Custom-tailored viruses. I should read that story again.

    --
    They sentenced me to twenty years of boredom
  13. Madame Virus Attack.. by Anonymous Coward · · Score: 0

    ...that is an strange name for a Virus :)

  14. Re: Solution to overpopulation? by Anonymous Coward · · Score: 0

    Of course, you will never include yourself and your kin as the recipients of those "harsh but necessary measures".

  15. I've got a "StRaNgE" theory on viruses... apk by Anonymous Coward · · Score: 0

    Personally (as I think we've blown our civilization(s) up in past millenia/eons) I think they're nano-machine weapon remmants of wars we had AGES ago albeit constructed on genetic machines instead of electro-mechanical ones!

    (Evidence on earth suggests past civilizations in anecdotes from iirc, Aristotle (or was it Socrates or Plato) on "Atlantis" OR in physical form, the "Biminy Road" on the floor of the ocean on the way to Cuba (iirc) + TONS more (Aztec/Mayan/Incan (not sure which) stone glyphics etc. of things that look like MODERN helicopters, guys riding on what looked like "jet cycles", VIMANA from India's legends (along w/ missiles), & even legends like Ragnarok from Norse myth, etc. - et al)

    * ... & like a paper I wrote up in academia, they're a SIMULATION of "full-blown life" in genetic nuclear material that wants to replicate & SURVIVE (what life does) & PROTECTS itself via evolving vs. threats to it also - my paper was about how computer viruses are a "new form of 'life'" (of a sort)... one that I suspect was a weapon that TURNED on us (both 'enemy parties' like mustard gas did on the Germans in WWI), & now we are actually IMPROVED from "fighting that fight" vs. them in the "current version" of humanity & acquired immunity (ala "War of the Worlds" type thought).

    APK

    P.S.=> Take that for what you will, rib on me IF you like, but "there ya are" for what it's worth based on speculation (but evidence that also backs it to a degree)... apk

  16. Guatemala by johnsie · · Score: 1

    The US have been experimenting on these sort of things for quite some time. They recently apologised for injecting Guatemalan detainees with STDs including syphilis https://www.nytimes.com/2010/1... One can only assume that this science has continued, but in a more clandestine manner.

    1. Re:Guatemala by AHuxley · · Score: 1

      A US Project Coast https://en.wikipedia.org/wiki/... ?

      --
      Domestic spying is now "Benign Information Gathering"
  17. Comment removed by account_deleted · · Score: 0

    Comment removed based on user account deletion

  18. Registered /.ers opinions of the Win64 model by Anonymous Coward · · Score: 0

    Your software is just fine - well written, functional... I'm going to continue using the Host File Engine by mmell February 17, 2017

    (APK's work), I've flat out said it's good by BronsCon February 11 2016

    his hosts program is actually pretty good by xenotransplant August 10 2015

    his hosts tool is actually useful for those cases in which one does indeed want to locally block stuff outright while consuming minimum system resources by alexgieg September 25 2015

    I like your host file system by Karmashock September 09 2015

    I do use APK's host file on all my systems at home by OrangeTide December 01 2017

    I personally use a HOSTS file blocker produced from a genius called APK by 110010001000 October 27 2017

    * See subject: Best part's the Linux 64-bit model's faster & more efficient (does 2x the work in 1/2 the time, literally)

    APK

    P.S.=> Enjoy a faster/safer/more reliable internet... apk

  19. Re: Limitations of deadly viruses / deadly bacteri by Anonymous Coward · · Score: 0

    The thing is, armor and sword evolve in lockstep, and in nature, a virus's "goal"- as determined by the virii we get more of and end up "keeping around"- is reproduction, which obviously involves something that is not lunatic levels of lethal.

    We are nowhere close to the lethalality limit of viruses, because viruses spent billiona of years figuring out how to survive, with the death and sickness side effects. We have never seen a virus that is a weapon, and if we are ever so unfortunate, the changes to what is left of society will be massive.

  20. Re:Solution to overpopulation? by Anonymous Coward · · Score: 0

    The planet can probably sustain a lot more, 50 billion perhaps, if we use the land area more thoughtfully, and rethink our whole attitude to consumption, energy efficiency, and waste processing and recycling. With everyone living like the average American schmuck, it will certainly not work.

    New attitudes and policies in all these areas could reduce consumption and production of waste per person to a fraction of what it is now.

  21. Then why bother with bioweapon by DrYak · · Score: 1

    If your point is to directly strike and not count on the weapon's own built-in capability to spread.
    (I.e.: you count on spreading viruses that will kill the host immediately without much chance of spreading further)
    why waste resource making *bio* weapon in the first place?

    Chemical warfare has been a reliable way to kill in scary gruesome ways already known and put to large scale use at least one century ago (yperite in WW1).

    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
    1. Re:Then why bother with bioweapon by angel'o'sphere · · Score: 1

      Chemical weapons usually only work under perfect conditions.
      Of course against civilians they work much better than against prepared soldiers.

      --
      Cost free eBook I read (by iBook/Kobo/Amazon/ObookO/Gutenberg etc.): "The Green Odyssey" by Philip Jose Farmer.
    2. Re:Then why bother with bioweapon by 1ucius · · Score: 1

      Presumably, you go bio because it has a simpler delivery mechanism.

    3. Re:Then why bother with bioweapon by EvilSS · · Score: 1

      It's easier to deploy, and it's more psychologically impactful. Chemical weapons have an immediate effect in a specific area. If you infect people in an area, those people won't immediately fall dead. They will move about and die slowly. People won't know if they are infected too. It would cause chaos. What you don't want is a bioweapon than can spread indefinitely. Those are the kinds of things that can get out of your control quickly and end up turning on your own forces.

      --
      I browse on +1 so AC's need not respond, I won't see it.
  22. Re: Limitations of deadly viruses / deadly bacteri by Anonymous Coward · · Score: 0

    Uh, no. TFA specifically references the total synthesis of poliovirus--and reproduction in the total absence of cell machinery.

    Viruses do not *require* cellular machinery. This was shown back in 2002.

  23. Re: Immigration by Anonymous Coward · · Score: 0

    You mean compared to the two and half billion killed by tobacco, lead in gasoline, vaccination shortages, rampant pollution and artificial food crises under capitalism?

  24. Re:Solution to overpopulation? by Anonymous Coward · · Score: 0

    Another crude understanding of the problem. It does correctly recognize there *IS* a problem.

    The "measures needed" are developments to third world shitholes. Turns out that when you do those, the birth rate plummets. Treat equality, education, human rights, poverty, shit like that, and the rate quickly dips to even, or less still. I'll be first to bat when the sjws lose perspective, but helping women in places that really need it has a significant birth rate effect, less dependency and access to normal careers, egalitarian stuff.

  25. chimera viruses by DrYak · · Score: 3, Informative

    various new diseases that our immune systems don't know how to handle.

    By definition our immune systems doesn't know how to handle disease (be it new or not) with a few exceptions,
    because our immune systems relies on adaptive immunity (with a few exceptions where the innate immunity can wipe a couple of pathogens).

    Our body have evolved not to handle only *known* pathogen (which would have been a pretty stupid strategy : such animal would be only 1 mutation away by a known pathogen to evade the innate immunity and wipe out the innate-only animal. Such animal would have been unfit and would have gone extinct if they ever hapenned to exist).

    Our body have evolved to be able to handle any unknown pathogen as long as they can survive long enough for the adaptive immunity to kick in, actually adapt and come up with a solution to wipe out the attacker.
    Works pretty well most of the time (most of the time, you don't even get sick, a few of the time you get sick but manage to fight off the infection. Only a few pathogen that have evolved ways to fuck up the adaptive immunity - e.g.: HIV fucks up the lymphocyte - or hide away -e.g.: rabbies achieves evasion by burrowing into the hard-to-access nervous system)

    And vaccination is basically just giving a "practice target" to the adaptive system to practice its adaptivity against and come up with an efficien wiping-out solution, before an actual occurrence of a disease.
    Its leveraging the same natural adaptive process that your body does every day against any upcoming as of yet unknown disease it encounters (and on some bad days, while already having caught and being sick from said just-yer-encountered disease).
    Your white blood cells are literally encountering crazy amount of new compounds every days and inventing new anti-bodies against them. Vaccination is just adding yet another compound on the list, because one day, you might encounter a pathogen with said compound on its surface that could make you sick.

    the semi mad ones have been doing it since the 1930s by using mouse brains and other animal tissues to grow or weaken the viruses used in vaccines. And in the process, transferring animal viruses into the human population causing various new diseases

    There is very little scientific research showing actual problems caused by vaccination. (e.g.: the "autism caused by vaccine" paper was retracted due to being actually bullshit).
    There is huge amount of litterature showing the actual benefits of vaccination (you can spend days hunting for meta-analysis about vaccinations on search engines like PubMed).

    I'm not aware of serious peer-reviewed scientific article showing that vaccine are a vector of animal viruses jumping to human hosts (again, please concentrate on serious scientific journal, that will anounce retraction if an article turns out to be bonker. Not click-baity random websites).

    The documented jump-over-species barrier are usually caused by combination of environmental exposure (e.g.: people working knee-deep in animal excrement) and by chimerisation due to co-infection (e.g.: a pig on a farm with dubious hygiene managing to get infected both by some bird-exclusive influenza and a human-compatile influenza. There's quite some research into this. Again rely on scientific publication from reputable sources.)

    So at that point you have to admit that the "cancers are caused by all the weird mouse-brain-vaccine-hybrids" doesn't sound a very compelling theory.
    Or that absolutely the whole planet is in a conspiration to hide the fact from you personally.

    Vaccines are safe, they are among the most well studied modern medicine.

    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
    1. Re:chimera viruses by rjdriver · · Score: 0

      A little Googling will help you find out more, but a good place to start is this book. https://www.amazon.com/Plague-...

    2. Re:chimera viruses by Anonymous Coward · · Score: 0

      You can vaccinate my cold dead corpse.

    3. Re:chimera viruses by Anonymous Coward · · Score: 0

      When someone says "Vaccines are safe,,," I find it fruitless to debate the issue on an Internet forum. But I invite you to do a little more digging. A book called Plague, by Kent Heckenlively and Judy Mikovits PHD is a good place to start.

      And of course, there is so much more out there if you are willing to look. The traditional sources (such as PubMed) may not show you the whole story. The medical research in this area has not always been controlled by the most ethical people, as Plague will spell out very plainly.

      To set the record straight, I am not anti vaccine. They can be a life saver. But I am very much against the aggressive vaccine schedule today's children in the US endure. I am also against combination vaccines like DTAP, MMR, etc. And I am very much against using animal tissue to grow/weaken vaccines, unless further steps are taken to ensure nothing unintended is being passed on. Extreme environmental exposure to animal viruses is hardly necessary to make the jump to humans when they are being injected directly into the blood stream.

  26. Re: Solution to overpopulation? by stealth_finger · · Score: 1

    Overpopulation consumes more resources and produces more environmental toxins. I asume rates grow exponentially as population grows. Overpopulation is the biggest man made impact on accelerated climate change, over fishing/hunting, and air, water and soil pollution. Reset is needed, sadly only the richest of the rich will be playing after the reset.

    Disease, starvation or war. Overpopulation will sort itself out one way or another.

    --
    Wanna buy a shirt?
    https://www.redbubble.com/people/stealthfinger/shop?asc=u
  27. Re:Solution to overpopulation? by stealth_finger · · Score: 1

    With everyone living like the average American schmuck, it will certainly not work.

    Luckily, it's only really americans that do that.

    --
    Wanna buy a shirt?
    https://www.redbubble.com/people/stealthfinger/shop?asc=u
  28. Just as long as by Anonymous Coward · · Score: 0

    they can target muslims exclusively. What's that - Islam isn't a race - how about you stop calling people who hate Islam racists then

  29. Y'all ever here the story.... by Anonymous Coward · · Score: 0

    Of this one biologist who developed this new strain of bacteria with these cool new genes that made it immune to very powerful antibiotics. A colleague wanted to try some experiments on it, so he wrote and asked for a few cells. "NO", the original developer replied. In a written letter he detailed how it was too dangerous to share this work. Undaunted, the second biologist carefully cut up the response letter, put the fragments in a petri dish with nutrients, grew a culture, and used antibiotics to filter out all but the new strain of bacteria.

    Moral of the story: This stuff gets everywhere. It's worse than a glitter bomb. Your terrorists need nation-state resources and top of the line gear to avoid self-infection.

    Ob reference: Frank Herbert, author of "Dune", also wrote "The White Plague".

  30. *groan* by Anonymous Coward · · Score: 0

    This has been obvious for years, but you do not talk about it, especially in a press release. This is one of those rare cases where security through obscurity matters because while the big players will understand these ideas already, there are plenty of idiots out there who will not start thinking this way on their own. And you don't hand idiots keys to kill lots of people just for your own press or CV.

    1. Re:*groan* by ledow · · Score: 1

      If you can obtain, use and apply the knowledge to create a virus from scratch or from a genetic blueprint, then it's a given that you must already have thought "What if?"

      The barrier here is the tech, the chance to apply it, and access to genetic structures. Not the intent, the capability, or "Oh, I didn't think of that".

      What stops this happening is international agreements to ban chemical/biological weapons, and that to get someone to do this requires a lab full of equipment that tends to cost a lot and arouse suspicion.

      Russia were MAKING their own nerve agents in the 70's and for decades before then. That's just as dangerous, if not more, and they are still using them. The only reason non-state terrorists aren't doing the same is that it's hard to do, needs an awful lot of equipment, is likely to kill you too, and it's just a damn sight cheaper to hijack a plane, drive a car at people, etc.

  31. Re: Solution to overpopulation? by Anonymous Coward · · Score: 0

    Genocide yay duck off

  32. Re: Solution to overpopulation? by Anonymous Coward · · Score: 0

    Last month it was Anonymous Cashews. Then it was Tardeau Lardeau. Last week it was The Fat Bastard. This week it is cre1mer and A Fat Bastard. Next week it will be cdre1mer.

    FatCashewsLoveMe should stick to one login and "polish" that turd as best as he can.

  33. Comment removed by account_deleted · · Score: 0

    Comment removed based on user account deletion

  34. Re:Solution to overpopulation? by Anonymous Coward · · Score: 0

    Unfortunately, when you bring those societies up to the level where their birthrate plummets they are also consuming resources at the same rate as the better off societies are now. And you cannot change that because it's not a societal thing, it's an animal thing. As animals at our core we all want the same thing, plentiful food, a safe warm place to sleep and the opportunity to procreate our brains out. A global pandemic is the short solution to this and the idea of a man-made plague fits that need. Not only would it take out a major part of the population but as a man-mad plague there would ab a vaccine ready for the chosen to have before the plague was released. It's so logical that it seems unreasonable.

  35. Re: Solution to overpopulation? by I+am+Jack's+username · · Score: 1

    > Disease, starvation or war. Overpopulation will sort itself out one way or another.

    Indeed, but human overpopulation is causing the anthropocene mass extinction event, so we're currently taking out most complex species along with us.

    Bioweapons are not the solution to the biosphere destroying problem of human overpopulation, because people will just go quiverfull to not let them there scientists tell them what to do.

    The only solution to human overpopulation I can see is if something like the anthropogenic climate change induced collapse of the West Antarctic Ice Sheet suddenly kills several billion people, which might make people realize that human overpopulation caused problems like anthropogenic climate change, the anthropocene mass extinction event, habitat degradation and destruction, factory farms, industrial fishing, etc. is a real problem, and that massively reducing our unsustainable overpopulation is the only thing that can fix it (except possibly for super general AI, which is more likely to be an existential risk rather than a solution).

  36. If not Nukes then viruses. by Anonymous Coward · · Score: 0

    During the cold war we all worried the world would end due to a nuclear war but I was wrong. Synthetic virus wars will destroy us.

  37. Re: Solution to overpopulation? by Anonymous Coward · · Score: 0

    To what end ? Why more people living worse lives ?

  38. Terrorists won't depend on natural infection by Tulsa_Time · · Score: 1

    Just keep dropping a fresh batch into whatever area you are targeting..

    --
    5 out of 6 people enjoy Russian Roulette & 6 out of 7 Dwarfs are not Happy
  39. Re:Solution to overpopulation? by Anonymous Coward · · Score: 0

    Earth is on its way to 10 billion. All of the growth is in economically, culturally and technologically unproductive areas of the planet. Can a virus be engineered to target those areas?

    Yes, this is harsh and horrible. Worse yet, if these designer viruses can be made to target certain races, then Progressives can finally achieve results the eugenics movement promised in the 1920s. Only this time they'll say its for the environment rather than wanting to get rid of imbeciles.

  40. Re:Immigration by GLMDesigns · · Score: 0, Offtopic

    The millennials are turning out to be libertarian not socialistic; individualistic not conformist. Millennials will sound the death knell to the hysteria among the left now - and the Republicans have been turning Libertarian and away from Social Conservatives. As of 2008 1/2 the Republicans / Conservatives under 30 were OK with gay marriage. Now, ten years later, it's pretty close to half the Republican party.

    That battle has been won. But that's not a good thing to Progressives as one must be outraged at all costs.

    The American Left is going through it's Communist Cultural Revolution (as the Chinese did in the 1960s). They've jumped the shark and millennials are not going to save them. Nope. Millennials are going to bury them.

    --
    If you're scared of your govt then you need to further restrict its powers
    Vote 3rd Party in 2016 and beyond
  41. Genebra Convention sends regards by rodrigoandrade · · Score: 1

    This is all totally FUD. Do you honestly think the left-wing nutjobs at the UN will let this through?

    As much as I support inflicting the most pain and suffering to the enemy (it's a fucking war, not a daycare center), I recognize this won't fly, since all bioweapons are banned already anyway.

  42. The Great Filter by Tablizer · · Score: 1

    This might explain Fermi's Paradox

  43. Pulling numbers from your ass again WindBourne by crimson+tsunami · · Score: 0

    Where did you get your 100+ million Indians? not even close
    Why do you constantly just make shit up? You must know I'll spend the 5 seconds to prove you are wrong...

    1. Re:Pulling numbers from your ass again WindBourne by WindBourne · · Score: 0
      Not even close? You are lying again. RIght from the link that you pulled

      Most scholars writing at the end of the 19th century estimated that the pre-Columbian population was as low as 10 million; by the end of the 20th century most scholars gravitated to a middle estimate of around 50 million, with some historians arguing for an estimate of 100 million or more

      Quit lying. It is all that you do regardless if you are red tide or porky.

      --
      I prefer the "u" in honour as it seems to be missing these days.
  44. Small Pox by Zorro · · Score: 1

    Create it again and release it on an International airplane ride.

    Your immunization is up to date?

  45. Prep & protect vs. manmade computer viruses by Anonymous Coward · · Score: 0

    See subject & via APK Hosts File Engine 2.0++ 64-bit for Linux h t t p : / / a p k . i t - m a t e . c o . u k / A P K H o s t s F i l e E n g i n e F o r L i n u x . z i p (remove spaces between characters & download).

    Yields more security/speed/reliability/anonymity vs. any SINGLE solution (99% of threats = hostnames vs. IP address (that most firewalls use)) more efficiently/FASTER + NATIVELY 4 less!

    (... Vs. "Bolt on 'MoAr' illogic-logic" competitors slowing you, hosts speed you up 2 ways (adblocks + hardcodes u spend most time @) vs. competition loaded w/ bugs (DNS/AntiVir) + their overheads (messagepass ('souled-out' to advertiser addons) + filtering drivers) & their complexity leads to exploitation).

    * Created in FreePascal/Lazarus 1.8.2 using GTK3 on OpenGL 3.1 via KDE Plasma desktop on Kubuntu 18.04 plus patches.

    APK

    P.S.=> Enjoy - it's much better vs. the Windows model on many fronts (speed & efficiency (plus new "merge" feature))... apk

  46. Registered /.ers opinions of the Win64 model by Anonymous Coward · · Score: 0

    Your software is just fine - well written, functional... I'm going to continue using the Host File Engine by mmell February 17, 2017

    (APK's work), I've flat out said it's good by BronsCon February 11 2016

    his hosts program is actually pretty good by xenotransplant August 10 2015

    his hosts tool is actually useful for those cases in which one does indeed want to locally block stuff outright while consuming minimum system resources by alexgieg September 25 2015

    I like your host file system by Karmashock September 09 2015

    I do use APK's host file on all my systems at home by OrangeTide December 01 2017

    I personally use a HOSTS file blocker produced from a genius called APK by 110010001000 October 27 2017

    * See subject: Best part's the Linux 64-bit model's faster/more efficient (does 2x the work in 1/2 the time)

    APK

    P.S.=> Enjoy a faster/safer/more reliable internet... apk

  47. Again with the baseless accusations (and lies) by crimson+tsunami · · Score: 1
    Hahaha, that's the unrealistic estimate for the whole of the America's, North and South, with the vast majority being in the South.

    While it is difficult to determine exactly how many Natives lived in North America before Columbus,[6] estimates range from a low of 2.1 million[7] to 7 million[8] people to a high of 18 million.

    Try again, where did you get your 100+ million native American Indians from?

    1. Re:Again with the baseless accusations (and lies) by WindBourne · · Score: 1
      And my statement was:

      There were 10's of MILLIONS, if not 100+ million, of Indians here,

      Unlike you, mine is accurate.
      So why do you continue to lie?

      --
      I prefer the "u" in honour as it seems to be missing these days.
    2. Re:Again with the baseless accusations (and lies) by crimson+tsunami · · Score: 1
      You couldn't just pretend you made a mistake, but had to double down on your lie?

      I hate sayings like this since no part of USA was EVER owned by Mexico. The New Spaniards/Mexicans were TRYING to take the now USA land from the natives, but they did not. In order to claim a land, you had to be the dominate ppl in there. There were 10's of MILLIONS, if not 100+ million, of Indians here, while the Mexicans never got over 250K in ALL of USA.

      You mentioned USA 3 times...

      While it is difficult to determine exactly how many Natives lived in North America before Columbus,[6] estimates range from a low of 2.1 million[7] to 7 million[8] people to a high of 18 million.

      The upper estimate of 18 million is barely even 10's of millions, it's clearly not 100+million...
      Again you lie at every twist and turn but claim others are lying.

    3. Re:Again with the baseless accusations (and lies) by WindBourne · · Score: 1

      It is 10s of millions asshole. You continue to lie over and over.

      --
      I prefer the "u" in honour as it seems to be missing these days.
    4. Re:Again with the baseless accusations (and lies) by Anonymous Coward · · Score: 0

      The largest estimate was 18 that's only 1 ten, not tens. But then English never was your specialty. Lying is about as close as you come to a specialty, but even that you aren't very good at. Even with all your practice.

  48. Re: Limitations of deadly viruses / deadly bacteri by houghi · · Score: 1

    And as we have seen in many documentaries made in Hollywood, do not spend to much in your underground layer that is a single point of failure. Also do not wait for some melodramic release.

    --
    Don't fight for your country, if your country does not fight for you.
  49. Re:Solution to overpopulation? by gnick · · Score: 1

    Hello, Adolf!

    The nice thing about a final solution is that you only have to use it once. If we could get these libtards to let go of their "the impoverished are people too" nonsense, we'd be in business.

    --
    He's getting rather old, but he's a good mouse.
  50. Re:Solution to overpopulation? by Anonymous Coward · · Score: 0

    Thanos did nothing wrong.

  51. If it's custom made by nehumanuscrede · · Score: 1

    There really isn't any means to " prepare " for it.

    You won't know the signature for it until after it is released. We can combine a payload with any number of existing pathogens altered just enough so the body won't know what it is, until it's too late.

    You can't prepare for this any more than you can prepare for the next computer virus that has yet to be released.

  52. Re:Solution to overpopulation? by terrycarlino · · Score: 1

    Sounds to me like we need to get Rainbow Six in on this. Don't they have experience dealing with eco-terrorists using bioweapons?

  53. Re:Solution to overpopulation? by Anonymous Coward · · Score: 0

    Hitler didn't even try to exterminate the Jews. He was a fucking Jew plant, for God's sake. But the idea of exterminating anyone who has ever benefited directly from Jew nepotism is a good one.

  54. Re: Immigration by Anonymous Coward · · Score: 0

    You mean compared to the two and half billion killed by tobacco, lead in gasoline, vaccination shortages, rampant pollution and artificial food crises under capitalism?

    For many Progressives who think we should cull the overcrowded world population, this would be a feature of capitalism. So stop complaining.

  55. Syphon Filter by Anonymous Coward · · Score: 0

    We already had iterations of this game.

  56. Controlled virus dna? by Anonymous Coward · · Score: 0

    I'm not usually in favor of censorship, but shouldn't virus dna be controlled the same way nuclear secrets are?

  57. Bad healthcare is now a national security risk by sjames · · Score: 1

    We have a resovour of millions of people who can't afford to see a doctor. They won't go unless it is clear that whatever they have is life threatening. Many more who could just afford a doctor won't go because sick days are either unpaid or carry an unwritten penalty come review time.

    If a bioweapon is released in the right areas we could be swamped before we even notice.

  58. Cisgender Attacks by Anonymous Coward · · Score: 0

    Get with the times, can we please be pc about this. :P

  59. Windy just making shit up by Anonymous Coward · · Score: 0

    AQ will not do it because of religious reasons.

    What religious reasons? Are you making up shit again Windy?

  60. not with a bang: It's an AK-47, not an atomic bomb by Anonymous Coward · · Score: 0

    The problem is not that the virus or bacteria is so bad that it will kill everyone anywhere.

    The problem is that pretty soon anyone will be able to make them.

    It will take 1 person hours to days to make something lethal and new to silently kill neighbors or the immigrants or the government official down the road. It will take months for 10's of highly-skilled scientists to figure out what happened, if it's even possible.

    No warlord uses nuclear bombs. They use AK-47's: cheap, available, easy to use, and lethal. Warlords rule most of the developing world.

    It is unstoppable. You can track nuclear materials, but all these materials and technologies are commonly available for good use.

    The only solution will be biological enclaves for the wealthy -- for a short time.

  61. Again with the baseless accusations (and lies) by crimson+tsunami · · Score: 1

    Again with baseless accusations, yet you wonder why I still like to point out your lies...
    Buy a clue WindBourne.

  62. WindBourne cures the common cold by crimson+tsunami · · Score: 1

    Rhino virus does NOT spread around the globe.

    I think WindBourne just discovered the cure for the common cold, just travel to another country and the virus won't be allowed in. I think it's because the virus doesn't have a passport and gets sent home.

    Maybe you can explain exactly how it works if I'm wrong?

  63. FYI pointing out WindBournes lie is never offtopic by crimson+tsunami · · Score: 1

    Pointing out WindBourne's lies isn't offtopic, it fits any topic he lies about, which is just about all of them.

  64. Re:Solution to overpopulation? by Anonymous Coward · · Score: 0

    But there will always be "impoverished" people. If you remove the bottom 10%, there will still be a bottom 10%. Look at the USA. People below the poverty line live in an air conditioned apartments, with a welfare phone, a tv, hot running water, and get fat on sugary foods. Oh that kings 200 years ago had such luxury!

    And don't joke about "only have to use it once." We got to as many people as we have today, because people reproduce. Kill even 99.99% of the worlds population and in a thousand years we will be right back where we are.

    If you really want to limit the population of a species, I think the predator prey relationship is what you're looking for. We need some top level, human hunting predator to keep the population in check. Preferably sharks that are drawn towards low pressure air vortecis acting on the water, with laser beams for eyes.

    Sarcasm aside, if you really want there to be less people, you can do your part by offing yourself. But in all honesty, there will tend to be more of the people who reproduce more. And a society that is adverse to the death and killing of its citizens will tend to be stronger than one that does not.

  65. Re:I've got a "StRaNgE" theory on viruses... apk by ebvwfbw · · Score: 1

    Whoa dude, you have been watching too many science fiction or conspiracy theory sites.

    We know where they come from. I remember as a kid it was usually the swine flu. That's because in third world countries they would raise pigs and ducks/fowl together. It would mutate a bit and take off, and come over here. Same thing today. Sometimes stuff remains dormant in people until they become old and weak, then it can infect and escape and start all over again.

    Just mother nature.

  66. Re: Solution to overpopulation? by Anonymous Coward · · Score: 0

    I blame religion for over population.

    I propose a simple rule. You can have kids or religion. If you want one you have to give up the other.

  67. "Perfect" bio-weapon virus by DrYak · · Score: 1

    If you infect people in an area, those people won't immediately fall dead. They will move about and die slowly. People won't know if they are infected too. It would cause chaos.

    So definitely *NOT* a fast-burning virus that infect{s} the people exposed to it immediately {killing them} in a gruesome way" as you proposed above.
    But something that spreads insidiously.

    What you don't want is a bioweapon than can spread indefinitely. Those are the kinds of things that can get out of your control quickly and end up turning on your own forces.

    Which brings us back to the main topic of discussion :

    - increasing the lethality of virus won't help doing that. If people start dying immediately, it won't move slowly, it will kill immediately a couple of people and then to move further due to absence of next victims in the immediate vicinity.
    Basically : you don't want to CRISPR-in some extra deadly stuff into you virus.

    - instead you could take a historically deadly virus that has spread wildly in the past, but was eradicated thank to vaccination, and mutate and/or tweak its surface antigens until it's not recognizable at all by the older antibodies. Then you make a vaccine against this new virus and keep it secret and vaccinate all your soldiers (and your civilians if possible, but at that scale it's going to be hard to keep the vaccine secret). You spread it on your target.
    Basically: you want to do what europeans managed to inflict to amerindian using smallpox (which the indian had never seen before and lacked anti-bodies).

    If you don't have the resources to mutate your own virus, it's even easiers: Do the "underdog influenza" - try to pick one of the minor emerging influenza strains that isn't predicted to go into the upcoming seasonal flue and isn't included in the latest vaccine mix that the WHO recommends and that vaccine maker cover.
    Simply grow that one and make your flu vaccine against that one using usual methods.
    (That regularly happens when WHO and the vaccine makers mis-predict which virus eventually does the seasonal flu. Except you do it on purpose and weaponize the mis-predicted virus strain).

    As a bonus :
    - the disease won't necessarily kill everyone immediately (smallpox might be fatal in adult but flu generally isn't as frequently) you seem more humane, while at the same time overloading the health care network of your adversary who'll have to divest resources from the war effort to handle the overcrowded hospitals.

    - eventually new (non-secret) vaccine can be created against the new virus and/or people will end-up developing an immunity, so by the time the war is over, the new virus won't pose any large-scale world-problem.
    You only need to have enough new viruses and secret vaccine to cover the period of war, while at the same time ramping up your own vaccine production against whatever your enemy throws at you. Basically playing bilateral cat-and-mouse with viruses.

    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
  68. Actually the best bio-weapon is flu by DrYak · · Score: 1

    Actually, flu is indeed the best bio-weapon.

    It's a virus that constantly mutate, new strains coming up constantly (see overcrowded regions with livestock you mention).
    Pick a minor variant that isn't predicted by WHO and vaccine manufacturer to become spread, and isn't thus on the list of variants covered by the upcoming seasonal flu vaccine.

    (e.g.: pick-up a minor variant that was quickly squashed and didn't get beyond a single farm, thanks to quick treatment of the farmer and quick killing of the sick livestock)

    Cultivate that one, and secretely make your vaccine against that one. Vaccinate your troops with your secret vaccine, spread the "alternate-flu" on your adversaries.

    Bonus point, as flu isn't extremely fatal, thus your enemy will have to divert resources away from war effort to take care of the over-flowing hostpitals.

    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
  69. Popular books vs. scientific publications by DrYak · · Score: 1

    Unlike publications in journals :
    - books don't undergo peer review
    - books don't have a mechanism for retraction

    (i.e.: You could publish whatever shit you want, as long as it's not pure libel and/or xenophobic hate-incitement.
    As long as it sells, there will be a publisher ready to print, no matter how close the content of the book is to what is currently considered truth).

    Books done by professional journalist are a good way to attract attention to some problem, but problems needs to investigate using scientific methods.
    i.e.: it's interesting if a journalist mention "that one study about {horrible thing} being caused by vaccines ! that THE BIG PHARMA INDUSTRY don't want you to hear about !"

    But if no other studies has managed to replicate the same result, it's worth shit.

    If a study turns out to have been done shodily (data manipulation) it can be retracted.
    Non-disclosed conflicts of interest can be added at a later point of view.

    In the scientific world, you need replication, multiple studies (all done as peer-reviewed professional publication).
    (Because a fluke can always happen)

    Then you need meta analysis : also peer-reviewed article that take the time to review all the various published studies up to there and look what's the most often found out come.
    You might found out that further studies mostly showed NO such {horrible thing} effect, there was one other result but it was due to the scientist having b0rked the data and got retracted, and only handful had actually the research receiving money from BIG PHARMA, the huge remaining part of studies are actually legit.

    Science's final opinion : it's safe. End of story (or at least until new data comes out and is replicated and is meta-analyzed)
    Publisher's opinion : hey, the books sells ! keep the printing machine working !

    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
  70. Book vs. publications ; Everyday immune system by DrYak · · Score: 1

    When someone says "Vaccines are safe,,," I find it fruitless to debate the issue on an Internet forum.

    Sorry, I'm from medical professional background, I'm aware of the problems that anti-vaxers are causing to population health (herd immunity is what I'm talking about) and thus I tend to over-react.

    But I invite you to do a little more digging. A book called Plague, by Kent Heckenlively and Judy Mikovits PHD is a good place to start.
    And of course, there is so much more out there if you are willing to look.

    Unlike publications in journals :
    - books don't undergo peer review
    - books don't have a mechanism for retraction
    (as long as it sells, it will get printed)

    I'm not saying that this peculiar book is shit (haven't read it), I'm just saying that there's no way to easily know if any book in your hands contains known shit.

    Books can bring attention to some not well enough considered problems, but problems needs to investigate using scientific methods.

    The traditional sources (such as PubMed) may not show you the whole story. The medical research in this area has not always been controlled by the most ethical people, as Plague will spell out very plainly.

    Yes, but did the articles get retracted following proof of result falsification or plain clumsiness b0rking the data analysis ? (as the famous "vaccine causes autism" article got).
    Did the missing conflict of interest got added where due ?

    Did further attempts to replicate the result fail to reproduce them ? (One study's result is interesting, but replication is key point, other wise you might be facing a random fluke without knowing it).

    What did meta-analysis determine is the general trend when reviewing all the published literature about a subject ? (That is the golden standard).

    I'm not saying that science never makes mistake (it does).
    I'm saying that science has methods to eventually self correct mistakes.

    That's why I'll rely more on what I read in scientific publication rather than in best-sellers.

    To set the record straight, I am not anti vaccine. They can be a life saver.

    Not only to you but to people around you who failed to develop immunity (the whole concept behind herd immunity).

    But I am very much against the aggressive vaccine schedule today's children in the US endure. I am also against combination vaccines like DTAP, MMR, etc.

    Keep in mind that your body is constantly exposed to a flux of new pathogens (viruses, bacteria, etc.) or of mutation in your body that needs to get eliminated (thing that would have had become cancer if your immune system didn't keep them in check).
    Even if you're not feeling sick, your body is constantly fighting aggressor, successfully (this success is the reason why you're not constantly sick despite the constant exposure).
    You only get sick once in a while when your body has managed to fight of the pathogens quickly enough.
    (Think of all the time you cut yourself in a non-sterile environment, say while preparing food, while working in your garage, etc. but didn't got an infection, only local redness)

    Even against a single target (a single attacking pathogen, against a single vaccination) your body will produce multiple antibodies. You don't produce a single anti-body against disease X, you produce several different antibodies which will all target various parts (e.g.: different surface glyco-proteins) of the targets. You neighbor with the same vaccine might produce different anti-bodies (but which will also manage to stick on the same target, but maybe at other parts).

    DTAP, MMR might sound scary to you, because it's *multiple target* in the same shot.
    - From the point of view of your body which is used to constantly fight of aggression, it's just business as usual. (Not much different from that other non-infected cut you got a few days ago while garden

    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
  71. Flu indeed by DrYak · · Score: 1

    but rather just the natural terrors that have arisen from places like The Congo and how the world is horribly unprepared for a repeat of the 1918 Flu Epidemic.

    Indeed the flu is a good exemple (well save for the high mortality which was due to europe being post-war).

    All it takes is WHO and the vaccine manufacturer to mis-predict which emerging new virus strains are likely to show up in that year's seasonal flu and produce a vaccine that's thus useless.
    And by random chance that missed strain being sufficiently different from anything else, so very few people happen to still have good antibodies laying around.

    And as the flu isn't destructive, it won't immediately kill the first couple of patient and then stop spreading for lack of finding new victims within sneezing range.
    It will instead spread slowly, taking over the whole population.
    Once people start to get sick and overcrowding doctor's waiting rooms and hospitals, society will be slowed down at a crippling pace and won't work as nicely.
    (Who's gonna save you from your house burning down if all the firefighters are sick at home in their beds ?)

    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]